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Pan-CDK inhibition augments cisplatin lethality in nasopharyngeal carcinoma cell lines and xenograft models.

Syn NL, Lim PL, Kong LR, Wang L, Wong AL, Lim CM, Loh TKS, Siemeister G, Goh BC, Hsieh WS.

Signal Transduct Target Ther. 2018 Apr 13;3:9. doi: 10.1038/s41392-018-0010-0. eCollection 2018.


Relationship between untimed plasma lopinavir concentrations and virological outcome on second-line antiretroviral therapy.

Mwasakifwa GE, Moore C, Carey D, Amin J, Penteado P, Losso M, Lim PL, Mohapi L, Molina JM, Gazzard B, Cooper DA, Boyd M; SECOND-LINE Study Group.

AIDS. 2018 Jan 28;32(3):357-361. doi: 10.1097/QAD.0000000000001688.


Zika beyond the Americas: Travelers as sentinels of Zika virus transmission. A GeoSentinel analysis, 2012 to 2016.

Leder K, Grobusch MP, Gautret P, Chen LH, Kuhn S, Lim PL, Yates J, McCarthy AE, Rothe C, Kato Y, Bottieau E, Huber K, Schwartz E, Stauffer W, Malvy D, Shaw MTM, Rapp C, Blumberg L, Jensenius M, van Genderen PJJ, Hamer DH; GeoSentinel Surveillance Network.

PLoS One. 2017 Oct 3;12(10):e0185689. doi: 10.1371/journal.pone.0185689. eCollection 2017.


Mapping infectious disease hospital surge threats to lessons learnt in Singapore: a systems analysis and development of a framework to inform how to DECIDE on planning and response strategies.

Singh SR, Coker R, Vrijhoef HJ, Leo YS, Chow A, Lim PL, Tan Q, Chen MI, Hildon ZJ.

BMC Health Serv Res. 2017 Sep 4;17(1):622. doi: 10.1186/s12913-017-2552-1.


Malaria after international travel: a GeoSentinel analysis, 2003-2016.

Angelo KM, Libman M, Caumes E, Hamer DH, Kain KC, Leder K, Grobusch MP, Hagmann SH, Kozarsky P, Lalloo DG, Lim PL, Patimeteeporn C, Gautret P, Odolini S, Chappuis F, Esposito DH; GeoSentinel Network.

Malar J. 2017 Jul 20;16(1):293. doi: 10.1186/s12936-017-1936-3.


Metabolic profiles of individuals switched to second-line antiretroviral therapy after failing standard first-line therapy for treatment of HIV-1 infection in a randomized, controlled trial.

Yao AH, Moore CL, Lim PL, Molina JM, Madero JS, Kerr S, Mallon PW, Emery S, Cooper DA, Boyd MA; SECOND-LINE study group.

Antivir Ther. 2018;23(1):21-32. doi: 10.3851/IMP3171.


Infectious diseases and migrant worker health in Singapore: a receiving country's perspective.

Sadarangani SP, Lim PL, Vasoo S.

J Travel Med. 2017 Jul 1;24(4). doi: 10.1093/jtm/tax014. Review.


Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients.

Leung DT, Lim PL, Cheung TH, Wong RR, Yim SF, Ng MH, Tam FC, Chung TK, Wong YF.

PLoS One. 2016 Aug 5;11(8):e0160412. doi: 10.1371/journal.pone.0160412. eCollection 2016.


Yellow fever cases in Asia: primed for an epidemic.

Wasserman S, Tambyah PA, Lim PL.

Int J Infect Dis. 2016 Jul;48:98-103. doi: 10.1016/j.ijid.2016.04.025. Epub 2016 May 6. Review.


Hepatitis B and C Co-Infection in HIV Patients from the TREAT Asia HIV Observational Database: Analysis of Risk Factors and Survival.

Chen M, Wong WW, Law MG, Kiertiburanakul S, Yunihastuti E, Merati TP, Lim PL, Chaiwarith R, Phanuphak P, Lee MP, Kumarasamy N, Saphonn V, Ditangco R, Sim BL, Nguyen KV, Pujari S, Kamarulzaman A, Zhang F, Pham TT, Choi JY, Oka S, Kantipong P, Mustafa M, Ratanasuwan W, Durier N, Chen YM.

PLoS One. 2016 Mar 2;11(3):e0150512. doi: 10.1371/journal.pone.0150512. eCollection 2016.


Measles in the 21st Century, a Continuing Preventable Risk to Travelers: Data From the GeoSentinel Global Network.

Sotir MJ, Esposito DH, Barnett ED, Leder K, Kozarsky PE, Lim PL, Gkrania-Klotsas E, Hamer DH, Kuhn S, Connor BA, Pradhan R, Caumes E; GeoSentinel Surveillance Network.

Clin Infect Dis. 2016 Jan 15;62(2):210-2. doi: 10.1093/cid/civ839. Epub 2015 Sep 23.


Middle East respiratory syndrome (MERS) in Asia: lessons gleaned from the South Korean outbreak.

Lim PL.

Trans R Soc Trop Med Hyg. 2015 Sep;109(9):541-2. doi: 10.1093/trstmh/trv064. No abstract available.


Differential diagnosis of illness in travelers arriving from Sierra Leone, Liberia, or Guinea: a cross-sectional study from the GeoSentinel Surveillance Network.

Boggild AK, Esposito DH, Kozarsky PE, Ansdell V, Beeching NJ, Campion D, Castelli F, Caumes E, Chappuis F, Cramer JP, Gkrania-Klotsas E, Grobusch MP, Hagmann SH, Hynes NA, Lim PL, López-Vélez R, Malvy DJ, Mendelson M, Parola P, Sotir MJ, Wu HM, Hamer DH; GeoSentinel Surveillance Network.

Ann Intern Med. 2015 Jun 2;162(11):757-64. doi: 10.7326/M15-0074.


CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa.

Geng EH, Neilands TB, Thièbaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, Bangsberg DR, Fox MP, Prozesky H, Hunt PW, Davies MA, Reynolds SJ, Egger M, Yiannoutsos CT, Vittinghoff EV, Deeks SG, Martin JN.

Int J Epidemiol. 2015 Feb;44(1):251-63.


Saccharomyces cerevisiae EC-1118 enhances the survivability of probiotic Lactobacillus rhamnosus HN001 in an acidic environment.

Lim PL, Toh M, Liu SQ.

Appl Microbiol Biotechnol. 2015 Aug;99(16):6803-11. doi: 10.1007/s00253-015-6560-y. Epub 2015 Apr 7.


Animal-associated exposure to rabies virus among travelers, 1997-2012.

Gautret P, Harvey K, Pandey P, Lim PL, Leder K, Piyaphanee W, Shaw M, McDonald SC, Schwartz E, Esposito DH, Parola P; GeoSentinel Surveillance Network.

Emerg Infect Dis. 2015 Apr;21(4):569-77. doi: 10.3201/eid2104.141479.


Impact of Gender on Long-Term Treatment Outcomes of Highly Active Antiretroviral Therapy (HAART) in the TREAT Asia HIV Observational Database.

Lee MP, Zhou J, Messerschmidt L, Honda M, Ditangco R, Sirisanthana T, Kumarasamy N, Phanuphak P, Chen YM, Zhang F, Saphonn V, Kiertiburanakul S, Lee CK, Pujari S, Choi JY, Kamarulzaman A, Yunihastuti E, Merati TP, Lim PL, Li PC; TREAT Asia HIV Observational Database.

AIDS Patient Care STDS. 2015 May;29(5):229-31. doi: 10.1089/apc.2014.0232. Epub 2015 Mar 16. No abstract available.


Avian influenza: recent epidemiology, travel-related risk, and management.

Lazarus R, Lim PL.

Curr Infect Dis Rep. 2015 Jan;17(1):456. doi: 10.1007/s11908-014-0456-3.


Travel and the globalization of emerging infections.

Lim PL.

Trans R Soc Trop Med Hyg. 2014 Jun;108(6):309-10. doi: 10.1093/trstmh/tru051. No abstract available.


DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.

Loh M, Liem N, Vaithilingam A, Lim PL, Sapari NS, Elahi E, Mok ZY, Cheng CL, Yan B, Pang B, Salto-Tellez M, Yong WP, Iacopetta B, Soong R.

BMC Gastroenterol. 2014 Mar 28;14:55. doi: 10.1186/1471-230X-14-55.


Diagnostic and prognostic utility of a DNA hypermethylated gene signature in prostate cancer.

Goh LK, Liem N, Vijayaraghavan A, Chen G, Lim PL, Tay KJ, Chang M, Low JS, Joshi A, Huang HH, Kalaw E, Tan PH, Hsieh WS, Yong WP, Alumkal J, Sim HG.

PLoS One. 2014 Mar 13;9(3):e91666. doi: 10.1371/journal.pone.0091666. eCollection 2014.


The significance of HIV 'blips' in resource-limited settings: is it the same? analysis of the treat Asia HIV Observational Database (TAHOD) and the Australian HIV Observational Database (AHOD).

Kanapathipillai R, McManus H, Kamarulzaman A, Lim PL, Templeton DJ, Law M, Woolley I.

PLoS One. 2014 Feb 7;9(2):e86122. doi: 10.1371/journal.pone.0086122. eCollection 2014.


Response 1 to letter.

Lim PL.

J Travel Med. 2014 Jan-Feb;21(1):73. doi: 10.1111/jtm.12073_2. No abstract available.


Travel-associated diseases, Indian Ocean Islands, 1997-2010.

Savini H, Gautret P, Gaudart J, Field V, Castelli F, López-Vélez R, Lim PL, Shaw M, von Sonnenburg F, Loutan L, Simon F; GeoSentinel Surveillance Network.

Emerg Infect Dis. 2013 Aug;19(8):1297-301. doi: 10.3201/eid1908.121739.


Schistosoma haematobium in China, ex-Africa: new populations at risk?

Lim PL.

J Travel Med. 2013 Jul-Aug;20(4):211-3. doi: 10.1111/jtm.12031. No abstract available.


Middle East Respiratory Syndrome coronavirus (MERS CoV): Update 2013.

Lim PL, Lee TH, Rowe EK.

Curr Infect Dis Rep. 2013 Aug;15(4):295-8. doi: 10.1007/s11908-013-0344-2.


Expatriates: special considerations in pretravel preparation.

Pierre CM, Lim PL, Hamer DH.

Curr Infect Dis Rep. 2013 Aug;15(4):299-306. doi: 10.1007/s11908-013-0342-4.


Rates and predictors for influenza vaccine prescriptions among HIV-infected clinic patients in Singapore.

Lim PL, Tan J, Yusoff Y, Win MK, Chow A.

Ann Acad Med Singapore. 2013 Apr;42(4):173-7.


International travelers as sentinels for sustained influenza transmission during the 2009 influenza A(H1N1)pdm09 pandemic.

Davis XM, Hay KA, Plier DA, Chaves SS, Lim PL, Caumes E, Castelli F, Kozarsky PE, Cetron MS, Freedman DO; GeoSentinel Surveillance Network.

J Travel Med. 2013 May-Jun;20(3):177-84. doi: 10.1111/jtm.12025. Epub 2013 Mar 14.


Effects of once-daily darunavir/ritonavir versus lopinavir/ritonavir on metabolic parameters in treatment-naive HIV-1-infected patients at week 96: ARTEMIS.

Arathoon E, Schneider S, Baraldi E, Lim PL, Opravil M, Van De Casteele T, Lavreys L.

Int J STD AIDS. 2013 Jan;24(1):12-7. doi: 10.1258/ijsa.2012.012120. Epub 2013 May 6.


Predictors of clinical progression in HIV-1-infected adults initiating combination antiretroviral therapy with advanced disease in the Asia-Pacific region: results from the TREAT Asia HIV observational database.

Byakwaga H, Petoumenos K, Ananworanich J, Zhang F, Boyd MA, Sirisanthana T, Li PC, Lee C, Mean CV, Saphonn V, Omar SF, Pujari S, Phanuphak P, Lim PL, Kumarasamy N, Chen YM, Merati TP, Sungkanuparph S, Ditangco R, Oka S, Tau G, Zhou J, Law MG, Emery S.

J Int Assoc Provid AIDS Care. 2013 Jul-Aug;12(4):270-7. doi: 10.1177/1545109712469684. Epub 2013 Feb 19.


Expatriates ill after travel: results from the Geosentinel Surveillance Network.

Lim PL, Han P, Chen LH, MacDonald S, Pandey P, Hale D, Schlagenhauf P, Loutan L, Wilder-Smith A, Davis XM, Freedman DO; GeoSentinel Surveillance Network.

BMC Infect Dis. 2012 Dec 31;12:386. doi: 10.1186/1471-2334-12-386.


Microbiological culture simplified using anti-O12 monoclonal antibody in TUBEX test to detect Salmonella bacteria from blood culture broths of enteric fever patients.

Nugraha J, Marpaung FR, Tam FC, Lim PL.

PLoS One. 2012;7(11):e49586. doi: 10.1371/journal.pone.0049586. Epub 2012 Nov 16.


The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers.

Subramaniam MM, Loh M, Chan JY, Liem N, Lim PL, Peng YW, Lim XY, Yeoh KG, Iacopetta B, Soong R, Salto-Tellez M.

Mol Carcinog. 2014 Feb;53(2):98-108. doi: 10.1002/mc.21951. Epub 2012 Aug 21.


A case of post-vaccination optic neuritis: coincidence or causative?

Sudarshan S, Huang EH, Lim PL, Leo YS, Lim SA.

Eye (Lond). 2012 Nov;26(11):1498. doi: 10.1038/eye.2012.146. Epub 2012 Aug 10. No abstract available.


Travel-associated illness in older adults (>60 y).

Gautret P, Gaudart J, Leder K, Schwartz E, Castelli F, Lim PL, Murphy H, Keystone J, Cramer J, Shaw M, Boddaert J, von Sonnenburg F, Parola P; GeoSentinel Surveillance Network.

J Travel Med. 2012 May-Jun;19(3):169-77. doi: 10.1111/j.1708-8305.2012.00613.x. Erratum in: J Travel Med. 2012 Jul;19(4):276. Cramer, Jacob [corrected to Cramer, Jakob].


Loss to Followup in HIV-Infected Patients from Asia-Pacific Region: Results from TAHOD.

Zhou J, Tanuma J, Chaiwarith R, Lee CK, Law MG, Kumarasamy N, Phanuphak P, Chen YM, Kiertiburanakul S, Zhang F, Vonthanak S, Ditangco R, Pujari S, Choi JY, Parwati Merati T, Yunihastuti E, Li PC, Kamarulzaman A, Nguyen VK, Thuy Pham TT, Lim PL.

AIDS Res Treat. 2012;2012:375217. doi: 10.1155/2012/375217. Epub 2012 Feb 22.


Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database.

Lim PL, Zhou J, Ditangco RA, Law MG, Sirisanthana T, Kumarasamy N, Chen YM, Phanuphak P, Lee CK, Saphonn V, Oka S, Zhang F, Choi JY, Pujari S, Kamarulzaman A, Li PC, Merati TP, Yunihastuti E, Messerschmidt L, Sungkanuparph S; TREAT Asia HIV Observational Database.

J Int AIDS Soc. 2012 Jan 26;15(1):1. doi: 10.1186/1758-2652-15-1.


Influenza and SARS: the impact of viral pandemics on maritime health.

Lim PL.

Int Marit Health. 2011;62(3):170-5.


Latitudinal patterns of travel among returned travelers with influenza: results from the GeoSentinel Surveillance Network, 1997-2007.

Boggild AK, Castelli F, Gautret P, Torresi J, von Sonnenburg F, Barnett ED, Greenaway CA, Lim PL, Schwartz E, Wilder-Smith A, Wilson ME; GeoSentinel Surveillance Network.

J Travel Med. 2012 Jan-Feb;19(1):4-8. doi: 10.1111/j.1708-8305.2011.00579.x. Epub 2011 Dec 8.


Combined rapid (TUBEX) test for typhoid-paratyphoid A fever based on strong anti-O12 response: design and critical assessment of sensitivity.

Yan M, Tam FC, Kan B, Lim PL.

PLoS One. 2011;6(9):e24743. doi: 10.1371/journal.pone.0024743. Epub 2011 Sep 15.


The potential utility of adjuvanted seasonal influenza vaccine for travelers.

Tsai TF, Lim PL, von Sonnenburg F, Clemens R.

J Travel Med. 2011 Jul-Aug;18(4):231-2. doi: 10.1111/j.1708-8305.2011.00527.x. Epub 2011 Jun 15. No abstract available.


Isotopic labeling of the heme cofactor in cytochrome P450 and other heme proteins.

Bryson D, Lim PL, Lawson A, Manjunath S, Raner GM.

Biotechnol Lett. 2011 Oct;33(10):2019-26. doi: 10.1007/s10529-011-0661-1. Epub 2011 Jun 10.


Isolation of the first three cases of Clostridium difficile polymerase chain reaction ribotype 027 in Singapore.

Lim PL, Ling ML, Lee HY, Koh TH, Tan AL, Kuijper EJ, Goh SS, Low BS, Ang LP, Harmanus C, Lin RT, Krishnan P, James L, Lee CE.

Singapore Med J. 2011 May;52(5):361-4.


Surveillance for Clostridium difficile infection: ICD-9 coding has poor sensitivity compared to laboratory diagnosis in hospital patients, Singapore.

Chan M, Lim PL, Chow A, Win MK, Barkham TM.

PLoS One. 2011 Jan 20;6(1):e15603. doi: 10.1371/journal.pone.0015603.


Trends in CD4 counts in HIV-infected patients with HIV viral load monitoring while on combination antiretroviral treatment: results from The TREAT Asia HIV Observational Database.

Zhou J, Sirisanthana T, Kiertiburanakul S, Chen YM, Han N, Lim PL, Kumarasamy N, Choi JY, Merati TP, Yunihastuti E, Oka S, Kamarulzaman A, Phanuphak P, Lee CK, Li PC, Pujari S, Saphonn V, Law MG.

BMC Infect Dis. 2010 Dec 23;10:361. doi: 10.1186/1471-2334-10-361.


Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors.

Petoumenos K, Hui E, Kumarasamy N, Kerr SJ, Choi JY, Chen YM, Merati T, Zhang F, Lim PL, Sungkanuparph S, Pujari S, Ponnampalavanar S, Ditangco R, Lee CK, Grulich A, Law MG; TREAT Asia HIV Observational Database.

J Int AIDS Soc. 2010 Dec 10;13:51. doi: 10.1186/1758-2652-13-51.


Chlorin e6-polyvinylpyrrolidone mediated photodynamic therapy--A potential bladder sparing option for high risk non-muscle invasive bladder cancer.

Lee LS, Thong PS, Olivo M, Chin WW, Ramaswamy B, Kho KW, Lim PL, Lau WK.

Photodiagnosis Photodyn Ther. 2010 Dec;7(4):213-20. doi: 10.1016/j.pdpdt.2010.08.005. Epub 2010 Sep 29.


Impact of sample heterogeneity on methylation analysis.

Loh M, Liem N, Lim PL, Vaithilingam A, Cheng CL, Salto-Tellez M, Yong WP, Soong R.

Diagn Mol Pathol. 2010 Dec;19(4):243-7. doi: 10.1097/PDM.0b013e3181de4396.


Vaccine preventable diseases in returned international travelers: results from the GeoSentinel Surveillance Network.

Boggild AK, Castelli F, Gautret P, Torresi J, von Sonnenburg F, Barnett ED, Greenaway CA, Lim PL, Schwartz E, Wilder-Smith A, Wilson ME; GeoSentinel Surveillance Network.

Vaccine. 2010 Oct 28;28(46):7389-95. doi: 10.1016/j.vaccine.2010.09.009. Epub 2010 Sep 17.


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