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Items: 21

1.

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease.

Begum AN, Jones MR, Lim GP, Morihara T, Kim P, Heath DD, Rock CL, Pruitt MA, Yang F, Hudspeth B, Hu S, Faull KF, Teter B, Cole GM, Frautschy SA.

J Pharmacol Exp Ther. 2008 Jul;326(1):196-208. doi: 10.1124/jpet.108.137455. Epub 2008 Apr 16.

2.

Teleconferencing using multimedia messaging service (MMS) for long-range consultation of patients with neurosurgical problems in an acute situation.

Waran V, Selladurai BM, Bahuri NF, George GJ, Lim GP, Khine M.

J Trauma. 2008 Feb;64(2):362-5; discussion 365. doi: 10.1097/TA.0b013e318070cc88.

PMID:
18301199
3.

Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.

Kotilinek LA, Westerman MA, Wang Q, Panizzon K, Lim GP, Simonyi A, Lesne S, Falinska A, Younkin LH, Younkin SG, Rowan M, Cleary J, Wallis RA, Sun GY, Cole G, Frautschy S, Anwyl R, Ashe KH.

Brain. 2008 Mar;131(Pt 3):651-64. doi: 10.1093/brain/awn008.

4.

Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models.

Ma QL, Harris-White ME, Ubeda OJ, Simmons M, Beech W, Lim GP, Teter B, Frautschy SA, Cole GM.

J Neurochem. 2007 Nov;103(4):1594-607. Epub 2007 Aug 30.

5.

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

Zhao L, Ma QL, Calon F, Harris-White ME, Yang F, Lim GP, Morihara T, Ubeda OJ, Ambegaokar S, Hansen JE, Weisbart RH, Teter B, Frautschy SA, Cole GM.

Nat Neurosci. 2006 Feb;9(2):234-42. Epub 2006 Jan 15.

PMID:
16415866
6.

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

Ma QL, Lim GP, Harris-White ME, Yang F, Ambegaokar SS, Ubeda OJ, Glabe CG, Teter B, Frautschy SA, Cole GM.

J Neurosci Res. 2006 Feb 15;83(3):374-84.

PMID:
16385556
7.

Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions.

Cole GM, Lim GP, Yang F, Teter B, Begum A, Ma Q, Harris-White ME, Frautschy SA.

Neurobiol Aging. 2005 Dec;26 Suppl 1:133-6. Epub 2005 Nov 2. Review.

PMID:
16266772
8.

Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease.

Calon F, Lim GP, Morihara T, Yang F, Ubeda O, Salem N Jr, Frautschy SA, Cole GM.

Eur J Neurosci. 2005 Aug;22(3):617-26.

PMID:
16101743
9.

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

Lim GP, Calon F, Morihara T, Yang F, Teter B, Ubeda O, Salem N Jr, Frautschy SA, Cole GM.

J Neurosci. 2005 Mar 23;25(12):3032-40.

10.

Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models.

Morihara T, Teter B, Yang F, Lim GP, Boudinot S, Boudinot FD, Frautschy SA, Cole GM.

Neuropsychopharmacology. 2005 Jun;30(6):1111-20.

11.

NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models.

Cole GM, Morihara T, Lim GP, Yang F, Begum A, Frautschy SA.

Ann N Y Acad Sci. 2004 Dec;1035:68-84. Review.

PMID:
15681801
12.

Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

Zhao L, Teter B, Morihara T, Lim GP, Ambegaokar SS, Ubeda OJ, Frautschy SA, Cole GM.

J Neurosci. 2004 Dec 8;24(49):11120-6.

13.

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM.

J Biol Chem. 2005 Feb 18;280(7):5892-901. Epub 2004 Dec 7.

14.

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model.

Calon F, Lim GP, Yang F, Morihara T, Teter B, Ubeda O, Rostaing P, Triller A, Salem N Jr, Ashe KH, Frautschy SA, Cole GM.

Neuron. 2004 Sep 2;43(5):633-45.

15.

Role of LRP in TGFbeta2-mediated neuronal uptake of Abeta and effects on memory.

Harris-White ME, Balverde Z, Lim GP, Kim P, Miller SA, Hammer H, Galasko D, Frautschy SA.

J Neurosci Res. 2004 Jul 15;77(2):217-28.

PMID:
15211588
16.

Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice.

Lim GP, Yang F, Chu T, Gahtan E, Ubeda O, Beech W, Overmier JB, Hsiao-Ashec K, Frautschy SA, Cole GM.

Neurobiol Aging. 2001 Nov-Dec;22(6):983-91.

PMID:
11755007
17.

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM.

J Neurosci. 2001 Nov 1;21(21):8370-7.

18.

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

Lim GP, Yang F, Chu T, Chen P, Beech W, Teter B, Tran T, Ubeda O, Ashe KH, Frautschy SA, Cole GM.

J Neurosci. 2000 Aug 1;20(15):5709-14.

19.

Matrix metalloproteinases in dog brains exhibiting Alzheimer-like characteristics.

Lim GP, Russell MJ, Cullen MJ, Tökés ZA.

J Neurochem. 1997 Apr;68(4):1606-11.

20.
21.

Matrix metalloproteinases in the neocortex and spinal cord of amyotrophic lateral sclerosis patients.

Lim GP, Backstrom JR, Cullen MJ, Miller CA, Atkinson RD, Tökés ZA.

J Neurochem. 1996 Jul;67(1):251-9.

PMID:
8666998

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