Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19

1.

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.

He X, Riceberg J, Soucy T, Koenig E, Minissale J, Gallery M, Bernard H, Yang X, Liao H, Rabino C, Shah P, Xega K, Yan ZH, Sintchak M, Bradley J, Xu H, Duffey M, England D, Mizutani H, Hu Z, Guo J, Chau R, Dick LR, Brownell JE, Newcomb J, Langston S, Lightcap ES, Bence N, Pulukuri SM.

Nat Chem Biol. 2017 Nov;13(11):1164-1171. doi: 10.1038/nchembio.2463. Epub 2017 Sep 11.

PMID:
28892090
2.

Acoustic Liquid Handling for Rapid siRNA Transfection Optimization.

Xiao AS, Lightcap ES, Bouck DC.

J Biomol Screen. 2015 Sep;20(8):957-64. doi: 10.1177/1087057115583808. Epub 2015 Apr 29.

PMID:
25924619
3.

Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.

Garcia K, Blank JL, Bouck DC, Liu XJ, Sappal DS, Hather G, Cosmopoulos K, Thomas MP, Kuranda M, Pickard MD, Liu R, Bandi S, Smith PG, Lightcap ES.

Mol Cancer Ther. 2014 Jun;13(6):1625-35. doi: 10.1158/1535-7163.MCT-13-0634. Epub 2014 Mar 26.

4.

Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924.

Blank JL, Liu XJ, Cosmopoulos K, Bouck DC, Garcia K, Bernard H, Tayber O, Hather G, Liu R, Narayanan U, Milhollen MA, Lightcap ES.

Cancer Res. 2013 Jan 1;73(1):225-34. doi: 10.1158/0008-5472.CAN-12-1729. Epub 2012 Oct 24.

5.

Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2.

Worster DT, Schmelzle T, Solimini NL, Lightcap ES, Millard B, Mills GB, Brugge JS, Albeck JG.

Sci Signal. 2012 Mar 6;5(214):ra19. doi: 10.1126/scisignal.2001986.

6.

Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.

Liao H, Liu XJ, Blank JL, Bouck DC, Bernard H, Garcia K, Lightcap ES.

Mol Cell Proteomics. 2011 Nov;10(11):M111.009183. doi: 10.1074/mcp.M111.009183. Epub 2011 Aug 26.

7.

Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib.

Chen S, Blank JL, Peters T, Liu XJ, Rappoli DM, Pickard MD, Menon S, Yu J, Driscoll DL, Lingaraj T, Burkhardt AL, Chen W, Garcia K, Sappal DS, Gray J, Hales P, Leroy PJ, Ringeling J, Rabino C, Spelman JJ, Morgenstern JP, Lightcap ES.

Cancer Res. 2010 Jun 1;70(11):4318-26. doi: 10.1158/0008-5472.CAN-09-4428. Epub 2010 May 11.

8.

MYC regulation of a "poor-prognosis" metastatic cancer cell state.

Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, Brugge JS, Ramaswamy S.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3698-703. doi: 10.1073/pnas.0914203107. Epub 2010 Feb 4.

9.

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis.

Schmelzle T, Mailleux AA, Overholtzer M, Carroll JS, Solimini NL, Lightcap ES, Veiby OP, Brugge JS.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3787-92. Epub 2007 Feb 26.

10.

Assays for proteasome inhibition.

Elliott PJ, Soucy TA, Pien CS, Adams J, Lightcap ES.

Methods Mol Med. 2003;85:163-72. Review. No abstract available.

PMID:
12710207
11.

Purification and inactivation of 3-hydroxyanthranilic acid 3,4-dioxygenase from beef liver.

Nandi D, Lightcap ES, Koo YK, Lu X, Quancard J, Silverman RB.

Int J Biochem Cell Biol. 2003 Jul;35(7):1085-97.

PMID:
12672479
12.

Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341.

Fleming JA, Lightcap ES, Sadis S, Thoroddsen V, Bulawa CE, Blackman RK.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1461-6.

13.

Proteasome inhibition measurements: clinical application.

Lightcap ES, McCormack TA, Pien CS, Chau V, Adams J, Elliott PJ.

Clin Chem. 2000 May;46(5):673-83.

14.

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination.

Podust VN, Brownell JE, Gladysheva TB, Luo RS, Wang C, Coggins MB, Pierce JW, Lightcap ES, Chau V.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4579-84.

15.

mu-Monothiopyrophosphate as a substrate for inorganic pyrophosphatase and UDP-glucose pyrophosphorylase.

Lightcap ES, Frey PA.

Arch Biochem Biophys. 1996 Nov 1;335(1):183-90.

PMID:
8914849
16.

Slow-binding inhibition of gamma-aminobutyric acid aminotransferase by hydrazine analogues.

Lightcap ES, Silverman RB.

J Med Chem. 1996 Feb 2;39(3):686-94.

PMID:
8576911
17.

Time-dependent inhibition of gamma-aminobutyric acid aminotransferase, by 3-hydroxybenzylhydrazine.

Lightcap ES, Hopkins MH, Olson GT, Silverman RB.

Bioorg Med Chem. 1995 May;3(5):579-85.

PMID:
7648206
19.

Interactions of metal ions with mu-monothiopyrophosphate.

Lightcap ES, Halkides CJ, Frey PA.

Biochemistry. 1991 Oct 22;30(42):10307-13.

PMID:
1657144

Supplemental Content

Loading ...
Support Center