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CYP3A4 mutation causes vitamin D-dependent rickets type 3.

Roizen JD, Li D, O'Lear L, Javaid MK, Shaw NJ, Ebeling PR, Nguyen HH, Rodda CP, Thummel KE, Thacher TD, Hakonarson H, Levine MA.

J Clin Invest. 2018 Feb 20. pii: 98680. doi: 10.1172/JCI98680. [Epub ahead of print]


Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms.

Negorev D, Beier UH, Zhang T, Quatromoni JG, Bhojnagarwala P, Albelda SM, Singhal S, Eruslanov E, Lohoff FW, Levine MH, Diamond JM, Christie JD, Hancock WW, Akimova T.

Sci Rep. 2018 Feb 16;8(1):3135. doi: 10.1038/s41598-018-21450-6.


Treatment of pancreatic cancer with intravenous vitamin C: a case report.

Drisko JA, Serrano OK, Spruce LR, Chen Q, Levine M.

Anticancer Drugs. 2018 Feb 12. doi: 10.1097/CAD.0000000000000603. [Epub ahead of print]


Liver Paired Exchange: Can the Liver Emulate the Kidney?

Mishra A, Lo A, Lee GS, Samstein B, Yoo PS, Levine MH, Goldberg DS, Shaked A, Olthoff KM, Abt PL.

Liver Transpl. 2018 Feb 10. doi: 10.1002/lt.25030. [Epub ahead of print]


Exploring the characteristics, global distribution and reasons for retraction of published articles involving human research participants: a literature survey.

Li G, Kamel M, Jin Y, Xu MK, Mbuagbaw L, Samaan Z, Levine MA, Thabane L.

J Multidiscip Healthc. 2018 Jan 18;11:39-47. doi: 10.2147/JMDH.S151745. eCollection 2018.


Vaccine failure and serologic response to live attenuated and inactivated influenza vaccines in children during the 2013-2014 season.

King JP, McLean HQ, Meece JK, Levine MZ, Spencer SM, Flannery B, Belongia EA.

Vaccine. 2018 Feb 21;36(9):1214-1219. doi: 10.1016/j.vaccine.2018.01.016.


Pharyngeal manifestations of gastroesophageal reflux disease.

Rubesin SE, Levine MS.

Abdom Radiol (NY). 2018 Feb 1. doi: 10.1007/s00261-018-1471-x. [Epub ahead of print]


GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S.

Nat Commun. 2018 Jan 26;9(1):387. doi: 10.1038/s41467-017-02697-5.


Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry.

Parrow NL, Violet PC, Tu H, Nichols J, Pittman CA, Fitzhugh C, Fleming RE, Mohandas N, Tisdale JF, Levine M.

J Vis Exp. 2018 Jan 12;(131). doi: 10.3791/56910.


Influence of Birth Cohort on Effectiveness of 2015-2016 Influenza Vaccine Against Medically Attended Illness Due to 2009 Pandemic Influenza A(H1N1) Virus in the United States.

Flannery B, Smith C, Garten RJ, Levine MZ, Chung JR, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Gaglani M, Murthy K, Zimmerman R, Nowalk MP, Griffin MR, Keipp Talbot H, Treanor JJ, Wentworth DE, Fry AM.

J Infect Dis. 2018 Jan 18. doi: 10.1093/infdis/jix634. [Epub ahead of print]


Kinetics of serological responses in critically ill patients hospitalized with influenza A(H1N1)pdm09 virus infection in Canada, 2009-2011.

Rolfes MA, Gross FL, Flannery B, Meyers AFA, Luo M, Bastien N, Fowler RA, Katz JM, Levine MZ, Kumar A, Uyeki TM; Canadian Severe Influenza Study (CSIS) and the Randomized, Double-Blinded Controlled Trial Comparing High vs Standard Dose Oseltamivir in Severe, Influenza Infection in ICU (ROSII) Study Groups.

J Infect Dis. 2018 Jan 12. doi: 10.1093/infdis/jiy013. [Epub ahead of print]


A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport.

Terry DS, Kolster RA, Quick M, LeVine MV, Khelashvili G, Zhou Z, Weinstein H, Javitch JA, Blanchard SC.

Nat Commun. 2018 Jan 15;9(1):230. doi: 10.1038/s41467-017-02202-y.


A systematic review of comparisons between protocols or registrations and full reports in primary biomedical research.

Li G, Abbade LPF, Nwosu I, Jin Y, Leenus A, Maaz M, Wang M, Bhatt M, Zielinski L, Sanger N, Bantoto B, Luo C, Shams I, Shahid H, Chang Y, Sun G, Mbuagbaw L, Samaan Z, Levine MAH, Adachi JD, Thabane L.

BMC Med Res Methodol. 2018 Jan 11;18(1):9. doi: 10.1186/s12874-017-0465-7.


Patterns of Discordance Between Pretransplant Imaging Stage of Hepatocellular Carcinoma and Posttransplant Pathologic Stage: A Contemporary Appraisal of the Milan Criteria.

Ecker BL, Hoteit MA, Forde KA, Hsu CC, Reddy KR, Furth EE, Siegelman ES, Habibollahi P, Ben-Josef E, Porrett PM, Abt PL, Shaked A, Olthoff KM, Levine MH.

Transplantation. 2018 Jan 10. doi: 10.1097/TP.0000000000002056. [Epub ahead of print]


Hypoglycemia and lactic acidosis outperform King's College criteria for predicting death or transplant in acetaminophen toxic patients.

Levine M, Stellpflug SJ, Pizon AF, Peak DA, Villano J, Wiegand T, Dib C, Thomas SH.

Clin Toxicol (Phila). 2018 Jan 5:1-4. doi: 10.1080/15563650.2017.1420193. [Epub ahead of print]


A scoping review of comparisons between abstracts and full reports in primary biomedical research.

Li G, Abbade LPF, Nwosu I, Jin Y, Leenus A, Maaz M, Wang M, Bhatt M, Zielinski L, Sanger N, Bantoto B, Luo C, Shams I, Shahid H, Chang Y, Sun G, Mbuagbaw L, Samaan Z, Levine MAH, Adachi JD, Thabane L.

BMC Med Res Methodol. 2017 Dec 29;17(1):181. doi: 10.1186/s12874-017-0459-5.


Measuring Influenza Neutralizing Antibody Responses to A(H3N2) Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells.

Gross FL, Bai Y, Jefferson S, Holiday C, Levine MZ.

J Vis Exp. 2017 Nov 22;(129). doi: 10.3791/56448.


Utility of IL-2 Complexes in Promoting the Survival of Murine Orthotopic Forelimb Vascularized Composite Allografts.

Xu H, Dahiya S, Wang L, Akimova T, Han R, Zhang T, Zhang Y, Qin L, Levine MH, Hancock WW, Levin LS.

Transplantation. 2018 Jan;102(1):70-78. doi: 10.1097/TP.0000000000001852.


Inflammatory biomarkers of low back pain and disc degeneration: a review.

Khan AN, Jacobsen HE, Khan J, Filippi CG, Levine M, Lehman RA Jr, Riew KD, Lenke LG, Chahine NO.

Ann N Y Acad Sci. 2017 Dec;1410(1):68-84. doi: 10.1111/nyas.13551. Review.


Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.

Reidling JC, Relaño-Ginés A, Holley SM, Ochaba J, Moore C, Fury B, Lau A, Tran AH, Yeung S, Salamati D, Zhu C, Hatami A, Cepeda C, Barry JA, Kamdjou T, King A, Coleal-Bergum D, Franich NR, LaFerla FM, Steffan JS, Blurton-Jones M, Meshul CK, Bauer G, Levine MS, Chesselet MF, Thompson LM.

Stem Cell Reports. 2018 Jan 9;10(1):58-72. doi: 10.1016/j.stemcr.2017.11.005. Epub 2017 Dec 7.


Cost-Effectiveness of Internet-Based Cognitive-Behavioral Treatment for Bulimia Nervosa: Results of a Randomized Controlled Trial.

Watson HJ, McLagan N, Zerwas SC, Crosby RD, Levine MD, Runfola CD, Peat CM, Moessner M, Zimmer B, Hofmeier SM, Hamer RM, Marcus MD, Bulik CM, Crow SJ.

J Clin Psychiatry. 2017 Dec 5;79(1). pii: 16m11314. doi: 10.4088/JCP.16m11314. [Epub ahead of print]


Stenosis of gastric sleeve after laparoscopic sleeve gastrectomy: clinical, radiographic and endoscopic findings.

Levy JL, Levine MS, Rubesin SE, Williams NN, Dumon KR.

Br J Radiol. 2018 Feb 6:20170702. doi: 10.1259/bjr.20170702. [Epub ahead of print]


Combination of Neoadjuvant Transcatheter Arterial Chemoembolization and Orthotopic Liver Transplantation for the Treatment of Cirrhotomimetic Hepatocellular Carcinoma.

Habibollahi P, Shamchi SP, Tondon R, Ecker BL, Gade TP, Hunt S, Soulen MC, Furth EE, Levine MH, Nadolski G.

J Vasc Interv Radiol. 2018 Feb;29(2):237-243. doi: 10.1016/j.jvir.2017.09.008. Epub 2017 Dec 6.


High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study.

Polireddy K, Dong R, Reed G, Yu J, Chen P, Williamson S, Violet PC, Pessetto Z, Godwin AK, Fan F, Levine M, Drisko JA, Chen Q.

Sci Rep. 2017 Dec 7;7(1):17188. doi: 10.1038/s41598-017-17568-8.


Population-Based Study to Determine the Health System Costs of Using the 21-Gene Assay.

Mittmann N, Earle CC, Cheng SY, Julian JA, Rahman F, Seung SJ, Levine MN.

J Clin Oncol. 2018 Jan 20;36(3):238-243. doi: 10.1200/JCO.2017.74.2577. Epub 2017 Dec 1.


Love as a Public Health Intervention.

Levine MJ, Cooney MA.

J Public Health Manag Pract. 2018 Jan/Feb;24(1):87-89. doi: 10.1097/PHH.0000000000000736. No abstract available.


Esophageal abnormalities in gastroesophageal reflux disease.

Levine MS, Carucci LR.

Abdom Radiol (NY). 2017 Nov 28. doi: 10.1007/s00261-017-1412-0. [Epub ahead of print]


Systematic review of the effect of denosumab on children with osteogenesis imperfecta showed inconsistent findings.

Li G, Jin Y, Levine MAH, Hoyer-Kuhn H, Ward L, Adachi JD.

Acta Paediatr. 2018 Mar;107(3):534-537. doi: 10.1111/apa.14154. Epub 2017 Dec 8. No abstract available.


Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter.

LeVine MV, Cuendet MA, Razavi AM, Khelashvili G, Weinstein H.

Biophys J. 2018 Jan 9;114(1):10-14. doi: 10.1016/j.bpj.2017.10.030. Epub 2017 Nov 15.


Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing?

Belsky DW, Moffitt TE, Cohen AA, Corcoran DL, Levine ME, Prinz JA, Schaefer J, Sugden K, Williams B, Poulton R, Caspi A.

Am J Epidemiol. 2017 Nov 15. doi: 10.1093/aje/kwx346. [Epub ahead of print]


State of the Science: Cancer Complementary and Alternative Medicine Therapeutics Research-NCI Strategic Workshop Highlights of Discussion Report.

Xi D, Bao T, Chen Q, Chen S, Cheng YC, Cullen J, Frank DA, Friedberg JW, Kronish I, Lee JE, Levine M, Li P, Li S, Lu W, Mao JJ, O'Keefe S, Rubinstein L, Shah MA, Standish L, Paller CJ, Chu E.

J Natl Cancer Inst Monogr. 2017 Nov 1;2017(52). doi: 10.1093/jncimonographs/lgx003.


Cell cycle proteins moonlight in multiciliogenesis.

Levine M, Holland A.

Science. 2017 Nov 10;358(6364):716-718. doi: 10.1126/science.aaq0770. No abstract available.


Direct Detection of Shigella in Stool Specimens by Use of a Metagenomic Approach.

Liu J, Almeida M, Kabir F, Shakoor S, Qureshi S, Zaidi A, Li S, Tamboura B, Sow SO, Mandomando I, Alonso PL, Ramamurthy T, Sur D, Kotloff K, Nataro J, Levine MM, Stine OC, Houpt E.

J Clin Microbiol. 2018 Jan 24;56(2). pii: e01374-17. doi: 10.1128/JCM.01374-17. Print 2018 Feb.


Complications in the 90-day postoperative period following kidney transplant and the relationship of the Charlson Comorbidity Index.

Levine MA, Schuler T, Gourishankar S.

Can Urol Assoc J. 2017 Dec;11(12):388-393. doi: 10.5489/cuaj.4378. Epub 2017 Nov 1.


Recombinant Human Parathyroid Hormone Effect on Health-Related Quality of Life in Adults With Chronic Hypoparathyroidism.

Vokes TJ, Mannstadt M, Levine MA, Clarke BL, Lakatos P, Chen K, Piccolo R, Krasner A, Shoback DM, Bilezikian JP.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):722-731. doi: 10.1210/jc.2017-01471.


Low quality evidence for treatment approaches for oro-antral communications.

Levine MH, Spivakovsky S.

Evid Based Dent. 2017 Oct 27;18(3):90-91. doi: 10.1038/sj.ebd.6401260.


Disorders of GNAS Inactivation.

Haldeman-Englert CR, Hurst ACE, Levine MA.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2017 Oct 26.


Prevalence of Pre-antiretroviral-Treatment Drug Resistance by Gender, Age, and Other Factors in HIV-Infected Individuals Initiating Therapy in Kenya, 2013-2014.

Silverman RA, Beck IA, Kiptinness C, Levine M, Milne R, McGrath CJ, Bii S, Richardson BA, John-Stewart G, Chohan B, Sakr SR, Kiarie JN, Frenkel LM, Chung MH.

J Infect Dis. 2017 Dec 19;216(12):1569-1578. doi: 10.1093/infdis/jix544.


The effect of costs on Kenyan households' demand for medical care: why time and distance matter.

Kukla M, McKay N, Rheingans R, Harman J, Schumacher J, Kotloff KL, Levine MM, Breiman R, Farag T, Walker D, Nasrin D, Omore R, O'Reilly C, Mintz E.

Health Policy Plan. 2017 Dec 1;32(10):1397-1406. doi: 10.1093/heapol/czx120.


Assessing Bleeding Risk in Patients With Intentional Overdoses of Novel Antiplatelet and Anticoagulant Medications.

Levine M, Beuhler MC, Pizon A, Cantrel FL, Spyres MB, LoVecchio F, Skolnik AB, Brooks DE.

Ann Emerg Med. 2018 Mar;71(3):273-278. doi: 10.1016/j.annemergmed.2017.08.046. Epub 2017 Oct 9.


Corrigendum: In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.

Ingle DJ, Valcanis M, Kuzevski A, Tauschek M, Inouye M, Stinear T, Levine MM, Robins-Browne RM, Holt KE.

Microb Genom. 2017 Aug 1;3(7):e000109. doi: 10.1099/mgen.0.000109. eCollection 2017 Jul.


A randomized, placebo-controlled, double-blind Phase 2 trial comparing the reactogenicity and immunogenicity of a single ≥2x108 colony forming units [cfu] standard-dose versus a ≥2x109 cfu high-dose of CVD 103-HgR live attenuated oral cholera vaccine, with Shanchol inactivated oral vaccine as an open label immunologic comparator.

Sow SO, Tapia MD, Chen WH, Haidara FC, Kotloff KL, Pasetti MF, Blackwelder WC, Traoré A, Tamboura B, Doumbia M, Diallo F, Coulibaly F, Onwuchekwa U, Kodio M, Tennant SM, Reymann M, Lam DF, Gurwith M, Lock M, Yonker T, Smith J, Simon JK, Levine MM.

Clin Vaccine Immunol. 2017 Oct 11. pii: CVI.00265-17. doi: 10.1128/CVI.00265-17. [Epub ahead of print]



Fukaya T, Levine M.

Curr Biol. 2017 Oct 9;27(19):R1047-R1049. doi: 10.1016/j.cub.2017.08.001.


Germline Genome Protection on an Evolutionary Treadmill.

Lee YCG, Levine MT.

Dev Cell. 2017 Oct 9;43(1):1-3. doi: 10.1016/j.devcel.2017.09.021. Review.


Outcomes of organ transplants when the donor is a prior recipient.

Lee GS, Goldberg DS, Levine MH, Abt PL.

Am J Transplant. 2018 Feb;18(2):492-503. doi: 10.1111/ajt.14536. Epub 2017 Nov 21.


Ligand modulation of sidechain dynamics in a wild-type human GPCR.

Clark LD, Dikiy I, Chapman K, Rödström KE, Aramini J, LeVine MV, Khelashvili G, Rasmussen SG, Gardner KH, Rosenbaum DM.

Elife. 2017 Oct 6;6. pii: e28505. doi: 10.7554/eLife.28505.


The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease.

Amir Shaghaghi M, Zhouyao H, Tu H, El-Gabalawy H, Crow GH, Levine M, Bernstein CN, Eck P.

Am J Clin Nutr. 2017 Dec;106(6):1508-1513. doi: 10.3945/ajcn.116.147603. Epub 2017 Sep 27.


The premarket assessment of the cost-effectiveness of a predictive technology "Straticyte™" for the early detection of oral cancer: a decision analytic model.

Khoudigian-Sinani S, Blackhouse G, Levine M, Thabane L, O'Reilly D.

Health Econ Rev. 2017 Oct 2;7(1):35. doi: 10.1186/s13561-017-0170-6.


A novel dominant COL11A1 mutation in a child with Stickler syndrome type II is associated with recurrent fractures.

Vogiatzi MG, Li D, Tian L, Garifallou JP, Kim CE, Hakonarson H, Levine MA.

Osteoporos Int. 2018 Jan;29(1):247-251. doi: 10.1007/s00198-017-4229-3. Epub 2017 Oct 3.


Typhoid vaccine development with a human challenge model.

Feasey NA, Levine MM.

Lancet. 2017 Dec 2;390(10111):2419-2421. doi: 10.1016/S0140-6736(17)32407-8. Epub 2017 Sep 28. No abstract available.

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