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Items: 1 to 50 of 641

1.

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior.

Sathyamurthy A, Johnson KR, Matson KJE, Dobrott CI, Li L, Ryba AR, Bergman TB, Kelly MC, Kelley MW, Levine AJ.

Cell Rep. 2018 Feb 20;22(8):2216-2225. doi: 10.1016/j.celrep.2018.02.003.

PMID:
29466745
2.

Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor Control.

Hayashi M, Hinckley CA, Driscoll SP, Moore NJ, Levine AJ, Hilde KL, Sharma K, Pfaff SL.

Neuron. 2018 Feb 21;97(4):869-884.e5. doi: 10.1016/j.neuron.2018.01.023. Epub 2018 Feb 1.

PMID:
29398364
3.

Membrane insertion of-and membrane potential sensing by-semiconductor voltage nanosensors: Feasibility demonstration.

Park K, Kuo Y, Shvadchak V, Ingargiola A, Dai X, Hsiung L, Kim W, Zhou H, Zou P, Levine AJ, Li J, Weiss S.

Sci Adv. 2018 Jan 12;4(1):e1601453. doi: 10.1126/sciadv.1601453. eCollection 2018 Jan.

4.

Reviewing the future of the P53 field.

Levine AJ.

Cell Death Differ. 2018 Jan;25(1):1-2. doi: 10.1038/cdd.2017.181. No abstract available.

PMID:
29227987
5.

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

Balachandran VP, Łuksza M, Zhao JN, Makarov V, Moral JA, Remark R, Herbst B, Askan G, Bhanot U, Senbabaoglu Y, Wells DK, Cary CIO, Grbovic-Huezo O, Attiyeh M, Medina B, Zhang J, Loo J, Saglimbeni J, Abu-Akeel M, Zappasodi R, Riaz N, Smoragiewicz M, Kelley ZL, Basturk O; Australian Pancreatic Cancer Genome Initiative; Garvan Institute of Medical Research; Prince of Wales Hospital; Royal North Shore Hospital; University of Glasgow; St Vincent’s Hospital; QIMR Berghofer Medical Research Institute; University of Melbourne, Centre for Cancer Research; University of Queensland, Institute for Molecular Bioscience; Bankstown Hospital; Liverpool Hospital; Royal Prince Alfred Hospital, Chris O’Brien Lifehouse; Westmead Hospital; Fremantle Hospital; St John of God Healthcare; Royal Adelaide Hospital; Flinders Medical Centre; Envoi Pathology; Princess Alexandria Hospital; Austin Hospital; Johns Hopkins Medical Institutes; ARC-Net Centre for Applied Research on Cancer, Gönen M, Levine AJ, Allen PJ, Fearon DT, Merad M, Gnjatic S, Iacobuzio-Donahue CA, Wolchok JD, DeMatteo RP, Chan TA, Greenbaum BD, Merghoub T, Leach SD.

Nature. 2017 Nov 23;551(7681):512-516. doi: 10.1038/nature24462. Epub 2017 Nov 8.

PMID:
29132146
6.

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.

Łuksza M, Riaz N, Makarov V, Balachandran VP, Hellmann MD, Solovyov A, Rizvi NA, Merghoub T, Levine AJ, Chan TA, Wolchok JD, Greenbaum BD.

Nature. 2017 Nov 23;551(7681):517-520. doi: 10.1038/nature24473. Epub 2017 Nov 8.

PMID:
29132144
7.

Why are there hotspot mutations in the TP53 gene in human cancers?

Baugh EH, Ke H, Levine AJ, Bonneau RA, Chan CS.

Cell Death Differ. 2018 Jan;25(1):154-160. doi: 10.1038/cdd.2017.180. Epub 2017 Nov 3. Review.

PMID:
29099487
8.

Folding sticky elastica: dynamics and reversibility of folds in Langmuir monolayers.

Foucard LC, Eaton JM, Dennin M, Levine AJ.

Soft Matter. 2017 Oct 4;13(38):6730-6742. doi: 10.1039/c6sm01382a.

PMID:
28819672
9.

The effect of facility-based antiretroviral therapy programs on outpatient services in Kenya and Uganda.

Wollum A, Dansereau E, Fullman N, Achan J, Bannon KA, Burstein R, Conner RO, DeCenso B, Gasasira A, Haakenstad A, Hanlon M, Ikilezi G, Kisia C, Levine AJ, Masters SH, Njuguna P, Okiro EA, Odeny TA, Allen Roberts D, Gakidou E, Duber HC.

BMC Health Serv Res. 2017 Aug 16;17(1):564. doi: 10.1186/s12913-017-2512-9.

10.

The interplay between epigenetic changes and the p53 protein in stem cells.

Levine AJ, Berger SL.

Genes Dev. 2017 Jun 15;31(12):1195-1201. doi: 10.1101/gad.298984.117. Review.

11.

A systematic review of studies of DNA methylation in the context of a weight loss intervention.

Aronica L, Levine AJ, Brennan K, Mi J, Gardner C, Haile RW, Hitchins MP.

Epigenomics. 2017 May;9(5):769-787. doi: 10.2217/epi-2016-0182. Review.

12.

Spatial distributions of pericellular stiffness in natural extracellular matrices are dependent on cell-mediated proteolysis and contractility.

Keating M, Kurup A, Alvarez-Elizondo M, Levine AJ, Botvinick E.

Acta Biomater. 2017 Jul 15;57:304-312. doi: 10.1016/j.actbio.2017.05.008. Epub 2017 May 5.

PMID:
28483696
13.

Association of long-term patterns of depressive symptoms and attention/executive function among older men with and without human immunodeficiency virus.

Armstrong NM, Surkan PJ, Treisman GJ, Sacktor NC, Irwin MR, Teplin LA, Stall R, Martin EM, Becker JT, Munro C, Levine AJ, Jacobson LP, Abraham AG.

J Neurovirol. 2017 Aug;23(4):558-567. doi: 10.1007/s13365-017-0527-y. Epub 2017 Apr 20.

14.

The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene.

Levine AJ.

Curr Top Microbiol Immunol. 2017;407:205-221. doi: 10.1007/82_2017_5.

PMID:
28349284
15.

Predictors and Impact of Self-Reported Suboptimal Effort on Estimates of Prevalence of HIV-Associated Neurocognitive Disorders.

Levine AJ, Martin E, Sacktor N, Munro C, Becker J; Multicenter AIDS Cohort Study-Neuropsychology Working Group.

J Acquir Immune Defic Syndr. 2017 Jun 1;75(2):203-210. doi: 10.1097/QAI.0000000000001371.

PMID:
28328547
16.

The association between physical activity and cognition in men with and without HIV infection.

Monroe AK, Zhang L, Jacobson LP, Plankey MW, Brown TT, Miller EN, Martin E, Becker JT, Levine AJ, Ragin A, Sacktor NC.

HIV Med. 2017 Sep;18(8):555-563. doi: 10.1111/hiv.12490. Epub 2017 Mar 13.

PMID:
28294530
17.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
18.

Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection.

Bryant AK, Moore DJ, Burdo TH, Lakritz JR, Gouaux B, Soontornniyomkij V, Achim CL, Masliah E, Grant I, Levine AJ, Ellis RJ.

AIDS. 2017 Apr 24;31(7):973-979. doi: 10.1097/QAD.0000000000001425.

PMID:
28244955
19.

Geometric localization of thermal fluctuations in red blood cells.

Evans AA, Bhaduri B, Popescu G, Levine AJ.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2865-2870. doi: 10.1073/pnas.1613204114. Epub 2017 Feb 27.

20.

Insights into immune system development and function from mouse T-cell repertoires.

Sethna Z, Elhanati Y, Dudgeon CS, Callan CG Jr, Levine AJ, Mora T, Walczak AM.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2253-2258. doi: 10.1073/pnas.1700241114. Epub 2017 Feb 14.

21.
22.

Discontinuous bundling transition in semiflexible polymer networks induced by Casimir interactions.

Kachan D, Müller KW, Wall WA, Levine AJ.

Phys Rev E. 2016 Sep;94(3-1):032505. Epub 2016 Sep 19.

PMID:
27739853
23.

Diagnostic utility of the HIV dementia scale and the international HIV dementia scale in screening for HIV-associated neurocognitive disorders among Spanish-speaking adults.

López E, Steiner AJ, Smith K, Thaler NS, Hardy DJ, Levine AJ, Al-Kharafi HT, Yamakawa C, Goodkin K.

Appl Neuropsychol Adult. 2017 Nov-Dec;24(6):512-521. doi: 10.1080/23279095.2016.1214835. Epub 2016 Aug 15.

PMID:
27712132
24.

Lysine methylation represses p53 activity in teratocarcinoma cancer cells.

Zhu J, Dou Z, Sammons MA, Levine AJ, Berger SL.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9822-7. doi: 10.1073/pnas.1610387113. Epub 2016 Aug 17.

25.

Inference of Ancestral Recombination Graphs through Topological Data Analysis.

Cámara PG, Levine AJ, Rabadán R.

PLoS Comput Biol. 2016 Aug 17;12(8):e1005071. doi: 10.1371/journal.pcbi.1005071. eCollection 2016 Aug.

26.

Rethinking the Regulatory Infrastructure for Human Gene Transfer Clinical Trials.

Jenkins CL, Bagarazzi ML, Kiem HP, Levine AJ, Ando D, June CH, Reid T, Emery DW.

Mol Ther. 2016 Aug;24(7):1173-7. doi: 10.1038/mt.2016.133. No abstract available.

27.

Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position.

Hilde KL, Levine AJ, Hinckley CA, Hayashi M, Montgomery JM, Gullo M, Driscoll SP, Grosschedl R, Kohwi Y, Kohwi-Shigematsu T, Pfaff SL.

Neuron. 2016 Aug 17;91(4):763-776. doi: 10.1016/j.neuron.2016.07.014. Epub 2016 Jul 28.

28.

Corrigendum to "Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer" [Drug Discov. Today 20 (11) (2015) 1391-1397].

Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR.

Drug Discov Today. 2016 Oct;21(10):1728. doi: 10.1016/j.drudis.2016.07.012. Epub 2016 Jul 29. No abstract available.

PMID:
27477875
29.

The potential to expand antiretroviral therapy by improving health facility efficiency: evidence from Kenya, Uganda, and Zambia.

Di Giorgio L, Moses MW, Fullman N, Wollum A, Conner RO, Achan J, Achoki T, Bannon KA, Burstein R, Dansereau E, DeCenso B, Delwiche K, Duber HC, Gakidou E, Gasasira A, Haakenstad A, Hanlon M, Ikilezi G, Kisia C, Levine AJ, Maboshe M, Masiye F, Masters SH, Mphuka C, Njuguna P, Odeny TA, Okiro EA, Roberts DA, Murray CJ, Flaxman AD.

BMC Med. 2016 Jul 20;14(1):108. doi: 10.1186/s12916-016-0653-z.

30.

Calculating the mean time to capture for tethered ligands and its effect on the chemical equilibrium of bound ligand pairs.

Shen L, Decker CG, Maynard HD, Levine AJ.

Data Brief. 2016 May 28;8:506-15. doi: 10.1016/j.dib.2016.05.050. eCollection 2016 Sep.

31.

The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation.

Levine AJ, Puzio-Kuter AM, Chan CS, Hainaut P.

Cold Spring Harb Perspect Med. 2016 Sep 1;6(9). pii: a026153. doi: 10.1101/cshperspect.a026153. Review.

PMID:
27352800
32.

Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination.

Camara PG, Rosenbloom DI, Emmett KJ, Levine AJ, Rabadan R.

Cell Syst. 2016 Jul;3(1):83-94. doi: 10.1016/j.cels.2016.05.008. Epub 2016 Jun 23.

33.

P53 and the defenses against genome instability caused by transposons and repetitive elements.

Levine AJ, Ting DT, Greenbaum BD.

Bioessays. 2016 Jun;38(6):508-13. doi: 10.1002/bies.201600031. Epub 2016 May 13. Review.

34.

Sexual dimorphism of liver metastasis by murine pancreatic neuroendocrine tumors is affected by expression of complement C5.

Contractor T, Kobayashi S, da Silva E, Clausen R, Chan C, Vosburgh E, Tang LH, Levine AJ, Harris CR.

Oncotarget. 2016 May 24;7(21):30585-96. doi: 10.18632/oncotarget.8874.

35.

Structural Evolution and Dynamics of the p53 Proteins.

Chillemi G, Kehrloesser S, Bernassola F, Desideri A, Dötsch V, Levine AJ, Melino G.

Cold Spring Harb Perspect Med. 2017 Apr 3;7(4). pii: a028308. doi: 10.1101/cshperspect.a028308. Review.

PMID:
27091942
36.

Bubble-raft collapse and the nonequilibrium dynamics of two-state elastica.

Kuo CC, Kachan D, Levine AJ, Dennin M.

Phys Rev E. 2016 Mar;93(3):032613. doi: 10.1103/PhysRevE.93.032613. Epub 2016 Mar 30.

PMID:
27078420
37.

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome.

Chau R, Dashti SG, Ait Ouakrim D, Buchanan DD, Clendenning M, Rosty C, Winship IM, Young JP, Giles GG, Macrae FA, Boussioutas A, Parry S, Figueiredo JC, Levine AJ, Ahnen DJ, Casey G, Haile RW, Gallinger S, Le Marchand L, Thibodeau SN, Lindor NM, Newcomb PA, Potter JD, Baron JA, Hopper JL, Jenkins MA, Win AK.

Int J Epidemiol. 2016 Jun;45(3):940-53. doi: 10.1093/ije/dyw036. Epub 2016 Apr 10.

38.

Role of Particle Focusing in Resistive-Pulse Technique: Direction-Dependent Velocity in Micropores.

Qiu Y, Vlassiouk I, Hinkle P, Toimil-Molares ME, Levine AJ, Siwy ZS.

ACS Nano. 2016 Mar 22;10(3):3509-17. doi: 10.1021/acsnano.5b07709. Epub 2016 Feb 25.

PMID:
26901283
39.

Fibroblast growth factor 2 dimer with superagonist in vitro activity improves granulation tissue formation during wound healing.

Decker CG, Wang Y, Paluck SJ, Shen L, Loo JA, Levine AJ, Miller LS, Maynard HD.

Biomaterials. 2016 Mar;81:157-168. doi: 10.1016/j.biomaterials.2015.12.003. Epub 2015 Dec 15.

40.

Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders.

Levine AJ, Quach A, Moore DJ, Achim CL, Soontornniyomkij V, Masliah E, Singer EJ, Gelman B, Nemanim N, Horvath S.

J Neurovirol. 2016 Jun;22(3):366-75. doi: 10.1007/s13365-015-0406-3. Epub 2015 Dec 21.

41.

The Evolution of Tumors in Mice and Humans with Germline p53 Mutations.

Levine AJ, Chan CS, Dudgeon C, Puzio-Kuter A, Hainaut P.

Cold Spring Harb Symp Quant Biol. 2015;80:139-45. doi: 10.1101/sqb.2015.80.027631. Epub 2015 Dec 7. Review.

PMID:
26642854
42.

Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV.

Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ.

J Neurovirol. 2016 Aug;22(4):431-41. doi: 10.1007/s13365-015-0410-7. Epub 2015 Dec 4.

43.

Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells.

Tanne A, Muniz LR, Puzio-Kuter A, Leonova KI, Gudkov AV, Ting DT, Monasson R, Cocco S, Levine AJ, Bhardwaj N, Greenbaum BD.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15154-9. doi: 10.1073/pnas.1517584112. Epub 2015 Nov 2.

44.

Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors.

Levine AJ, Phipps AI, Baron JA, Buchanan DD, Ahnen DJ, Cohen SA, Lindor NM, Newcomb PA, Rosty C, Haile RW, Laird PW, Weisenberger DJ.

Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):68-75. doi: 10.1158/1055-9965.EPI-15-0935. Epub 2015 Oct 28.

45.

The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain.

D'Abramo M, Bešker N, Desideri A, Levine AJ, Melino G, Chillemi G.

Oncogene. 2016 Jun 23;35(25):3272-81. doi: 10.1038/onc.2015.388. Epub 2015 Oct 19.

46.

DTIE, a novel core promoter element that directs start site selection in TATA-less genes.

Marbach-Bar N, Bahat A, Ashkenazi S, Golan-Mashiach M, Haimov O, Wu SY, Chiang CM, Puzio-Kuter A, Hirshfield KM, Levine AJ, Dikstein R.

Nucleic Acids Res. 2016 Feb 18;44(3):1080-94. doi: 10.1093/nar/gkv1032. Epub 2015 Oct 12.

47.

BK virus capsid antibodies are associated with protection against subsequent development of PML in HIV-infected patients.

Rossi F, Li X, Jacobson L, Levine AJ, Chen Y, Palella FJ, Margolick J, Viscidi R.

Virology. 2015 Nov;485:467-72. doi: 10.1016/j.virol.2015.08.022. Epub 2015 Sep 7.

48.

The role of chemokine C-C motif ligand 2 genotype and cerebrospinal fluid chemokine C-C motif ligand 2 in neurocognition among HIV-infected patients.

Thames AD, Briones MS, Magpantay LI, Martinez-Maza O, Singer EJ, Hinkin CH, Morgello S, Gelman BB, Moore DJ, Heizerling K, Levine AJ.

AIDS. 2015 Jul 31;29(12):1483-91. doi: 10.1097/QAD.0000000000000706.

49.

Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer.

Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR.

Drug Discov Today. 2015 Nov;20(11):1391-7. doi: 10.1016/j.drudis.2015.07.006. Epub 2015 Jul 20. Review. Erratum in: Drug Discov Today. 2016 Oct;21(10 ):1728.

50.

Stem cells, aging and cancers.

Levine AJ.

Aging (Albany NY). 2015 Jul;7(7):457-8. No abstract available.

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