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Pitfalls in assessing chorioamnionicity: novel observations and literature review.

Lu J, Cheng YKY, Ting YH, Law KM, Leung TY.

Am J Obstet Gynecol. 2018 Feb 17. pii: S0002-9378(18)30154-6. doi: 10.1016/j.ajog.2018.02.010. [Epub ahead of print] Review.


Is it time to move towards non-invasive prenatal screening for Down syndrome and screening for pre-eclampsia?

Wang R, Chien P, Leung TY.

BJOG. 2018 Mar;125(4):397-398. doi: 10.1111/1471-0528.15126. No abstract available.


Noninvasive reconstruction of placental methylome from maternal plasma DNA: Potential for prenatal testing and monitoring.

Sun K, Lun FMF, Leung TY, Chiu RWK, Lo YMD, Sun H.

Prenat Diagn. 2018 Jan 15. doi: 10.1002/pd.5214. [Epub ahead of print]


Body mass index at 11-13 weeks' gestation and pregnancy complications in a Southern Chinese population: a retrospective cohort study.

Chaemsaithong P, Leung TY, Sahota D, Cheng YKY, Leung WC, Lo TK, Poon LCY.

J Matern Fetal Neonatal Med. 2018 Jan 21:1-13. doi: 10.1080/14767058.2018.1424824. [Epub ahead of print]


Uses of FloSeal© in obstetric hemorrhage: Case series and literature review.

Chung JP, Leung TY.

Taiwan J Obstet Gynecol. 2017 Dec;56(6):827-830. doi: 10.1016/j.tjog.2017.10.022.


Maternal height and risk of hypertensive disorders in pregnancy.

Lao TT, Hui ASY, Sahota DS, Leung TY.

J Matern Fetal Neonatal Med. 2017 Dec 17:1-6. doi: 10.1080/14767058.2017.1410786. [Epub ahead of print]


Women's preference for non-invasive prenatal DNA testing versus chromosomal microarray after screening for Down syndrome: a prospective study.

Cheng Y, Leung WC, Leung TY, Choy KW, Chiu R, Lo TK, Kwok KY, Sahota DS.

BJOG. 2018 Mar;125(4):451-459. doi: 10.1111/1471-0528.15022. Epub 2018 Jan 14.


Identification of balanced chromosomal rearrangements previously unknown among participants in the 1000 Genomes Project: implications for interpretation of structural variation in genomes and the future of clinical cytogenetics.

Dong Z, Wang H, Chen H, Jiang H, Yuan J, Yang Z, Wang WJ, Xu F, Guo X, Cao Y, Zhu Z, Geng C, Cheung WC, Kwok YK, Yang H, Leung TY, Morton CC, Cheung SW, Choy KW.

Genet Med. 2017 Nov 2. doi: 10.1038/gim.2017.170. [Epub ahead of print]


Acceptance towards giving birth to a child with beta-thalassemia major - A prospective study.

Chan YM, Chan OK, Cheng YKY, Leung TY, Lao TTH, Sahota DS.

Taiwan J Obstet Gynecol. 2017 Oct;56(5):618-621. doi: 10.1016/j.tjog.2017.08.007.


First trimester screening for pre-eclampsia in Chinese pregnancies: case-control study.

Cheng Y, Leung TY, Law LW, Ting YH, Law KM, Sahota DS.

BJOG. 2018 Mar;125(4):442-449. doi: 10.1111/1471-0528.14970. Epub 2018 Jan 11.


The transverse technique; a complementary approach to the measurement of first-trimester uterine artery Doppler.

Drouin O, Johnson JA, Chaemsaithong P, Metcalfe A, Huber J, Schwarzenberger J, Winters E, Stavness L, Tse AWT, Lu J, Lim WT, Leung TY, Bujold E, Sahota D, Poon LC.

Ultrasound Obstet Gynecol. 2017 Oct 4. doi: 10.1002/uog.18917. [Epub ahead of print]


First Report of a Novel Deletion Due to εγδβ-Thalassemia in a Chinese Family.

Hui ASY, Au PKC, Ting YH, Kan ASY, Cheng YKY, Leung AWK, Chan KYK, Li CK, Tang MHY, Leung TY.

Hemoglobin. 2017 May;41(3):175-179. doi: 10.1080/03630269.2017.1366918.


Expanded newborn metabolic screening programme in Hong Kong: a three-year journey.

Chong SC, Law LK, Hui J, Lai CY, Leung TY, Yuen YP.

Hong Kong Med J. 2017 Oct;23(5):489-96. doi: 10.12809/hkmj176274. Epub 2017 Sep 1.


Prediction of labor outcome using serial transperineal ultrasound in the first stage of labor.

Chor CM, Poon LCY, Leung TY.

J Matern Fetal Neonatal Med. 2017 Oct 3:1-7. doi: 10.1080/14767058.2017.1369946. [Epub ahead of print]


Systematic Selection of Reference Genes for the Normalization of Circulating RNA Transcripts in Pregnant Women Based on RNA-Seq Data.

Chim SSC, Wong KKW, Chung CYL, Lam SKW, Kwok JSL, Lai CY, Cheng YKY, Hui ASY, Meng M, Chan OK, Tsui SKW, Lee KY, Chan TF, Leung TY.

Int J Mol Sci. 2017 Aug 4;18(8). pii: E1709. doi: 10.3390/ijms18081709.


Triplet pregnancy with fetal reduction: experience in Hong Kong.

Tse WT, Law LW, Sahota DS, Leung TY, Cheng YK.

Hong Kong Med J. 2017 Aug;23(4):326-32. doi: 10.12809/hkmj176267. Epub 2017 Jun 23.


Uterine artery pulsatility index in the first trimester: assessment of intersonographer and intersampling site measurement differences.

Chaemsaithong P, Ting YH, Cheng KYY, Poon CYL, Leung TY, Sahota DS.

J Matern Fetal Neonatal Med. 2017 Jul 11:1-8. doi: 10.1080/14767058.2017.1341481. [Epub ahead of print]


Antenatal diagnosis and management of foetal intestinal volvulus.

Yip KW, Cheng YKY, Leung TY.

Med J Malaysia. 2017 Apr;72(2):126-127.


Prospective Assessment of the INTERGROWTH-21 and WHO Estimated Fetal Weight Reference Curve.

Cheng YKY, Lu J, Leung TY, Chan YM, Sahota DS.

Ultrasound Obstet Gynecol. 2017 Apr 28. doi: 10.1002/uog.17514. [Epub ahead of print]


Maternal rubella immunity status and pre-eclampsia.

Lao TT, Sahota DS, Law LW, Leung TY.

Am J Reprod Immunol. 2017 Jul;78(1). doi: 10.1111/aji.12677. Epub 2017 Mar 30.


Single-Stranded DNA Library Preparation Preferentially Enriches Short Maternal DNA in Maternal Plasma.

Vong JSL, Tsang JCH, Jiang P, Lee WS, Leung TY, Chan KCA, Chiu RWK, Lo YMD.

Clin Chem. 2017 May;63(5):1031-1037. doi: 10.1373/clinchem.2016.268656. Epub 2017 Mar 9.


Prenatal Diagnosis of a Retroesophageal Left Brachiocephalic Vein: Two Case Reports.

Cheng YKY, Law KM, Chak PK, To KF, Chan YM, Leung TY.

J Ultrasound Med. 2017 May;36(5):1065-1069. doi: 10.7863/ultra.16.05003. Epub 2017 Mar 4.


Identification of fragile X pre-mutation carriers in the Chinese obstetric population using a robust FMR1 polymerase chain reaction assay: implications for screening and prenatal diagnosis.

Cheng YK, Lin CS, Kwok YK, Chan YM, Lau TK, Leung TY, Choy KW.

Hong Kong Med J. 2017 Apr;23(2):110-6. doi: 10.12809/hkmj164936. Epub 2017 Mar 3.


Establishing Prenatal Surgery for Myelomeningocele in Asia: The Singapore Consensus.

Wataganara T, Seshadri S, Leung TY, Matter C, Ngerncham M, Triyasunant N, Mali PV, Biswas A, Nawapun K, Phithakwatchara N, Flake AW, Johnson MP, Biswas A, Choolani M.

Fetal Diagn Ther. 2017;41(3):161-178. doi: 10.1159/000452218. Epub 2017 Feb 21. Review.


Preface: Issue 39.

Leung TY.

Best Pract Res Clin Obstet Gynaecol. 2017 Feb;39:1-2. doi: 10.1016/j.bpobgyn.2016.11.001. Epub 2016 Nov 20. No abstract available.


Gestational Age Assessment by Methylation and Size Profiling of Maternal Plasma DNA: A Feasibility Study.

Jiang P, Tong YK, Sun K, Cheng SH, Leung TY, Chan KC, Chiu RW, Lo YM.

Clin Chem. 2017 Feb;63(2):606-608. doi: 10.1373/clinchem.2016.265702. Epub 2016 Dec 15. No abstract available.


Combined Count- and Size-Based Analysis of Maternal Plasma DNA for Noninvasive Prenatal Detection of Fetal Subchromosomal Aberrations Facilitates Elucidation of the Fetal and/or Maternal Origin of the Aberrations.

Yu SC, Jiang P, Chan KC, Faas BH, Choy KW, Leung WC, Leung TY, Lo YM, Chiu RW.

Clin Chem. 2017 Feb;63(2):495-502. doi: 10.1373/clinchem.2016.254813. Epub 2016 Dec 14.


The pattern of cervical smear abnormalities in marginalised women in Hong Kong.

Ting YH, Tse HY, Lam WC, Chan KS, Leung TY.

Hong Kong Med J. 2017 Feb;23(1):28-34. doi: 10.12809/hkmj164887. Epub 2016 Dec 14.


Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases.

Hui WW, Jiang P, Tong YK, Lee WS, Cheng YK, New MI, Kadir RA, Chan KC, Leung TY, Lo YM, Chiu RW.

Clin Chem. 2017 Feb;63(2):513-524. doi: 10.1373/clinchem.2016.268375. Epub 2016 Dec 8.


Prenatal detection of 10q22q23 duplications: dilemmas in phenotype prediction.

Kong GW, Cao Y, Huang J, Cheng KY, Pursley AN, Rosenfeld JA, Edwards JG, Chan YM, Cheung SW, Leung TY, Choy KW.

Prenat Diagn. 2016 Dec;36(13):1211-1216. doi: 10.1002/pd.4959. Epub 2016 Nov 29.


Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends.

Chan KC, Jiang P, Sun K, Cheng YK, Tong YK, Cheng SH, Wong AI, Hudecova I, Leung TY, Chiu RW, Lo YM.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8159-E8168. Epub 2016 Oct 31.


Impact of replacing Chinese ethnicity-specific fetal biometry charts with the INTERGROWTH-21(st) standard.

Cheng Y, Leung TY, Lao T, Chan YM, Sahota DS.

BJOG. 2016 Sep;123 Suppl 3:48-55. doi: 10.1111/1471-0528.14008.


Debates on fetal fraction measurement and DNA-based noninvasive prenatal screening: time for standardisation?

Wataganara T, Bui TH, Choy KW, Leung TY.

BJOG. 2016 Sep;123 Suppl 3:31-5. doi: 10.1111/1471-0528.14197. No abstract available.


Cell-free DNA in maternal plasma and serum: A comparison of quantity, quality and tissue origin using genomic and epigenomic approaches.

Wong FC, Sun K, Jiang P, Cheng YK, Chan KC, Leung TY, Chiu RW, Lo YM.

Clin Biochem. 2016 Dec;49(18):1379-1386. doi: 10.1016/j.clinbiochem.2016.09.009. Epub 2016 Sep 9.


Procedure-Related Fetal Loss following Chorionic Villus Sampling after First-Trimester Aneuploidy Screening.

Wah YM, Leung TY, Cheng YKY, Sahota DS.

Fetal Diagn Ther. 2017;41(3):184-190. doi: 10.1159/000447538. Epub 2016 Jul 12.


FetalQuantSD: accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA.

Jiang P, Peng X, Su X, Sun K, Yu SCY, Chu WI, Leung TY, Sun H, Chiu RWK, Lo YMD, Chan KCA.

NPJ Genom Med. 2016 May 11;1:16013. doi: 10.1038/npjgenmed.2016.13. eCollection 2016.


Validation of a robust PCR-based assay for quantifying fragile X CGG repeats.

Kwok YK, Wong KM, Lo FM, Kong GWS, Moore JK, Wu S, Lam STS, Schermer M, Leung TY, Choy KW.

Clin Chim Acta. 2016 May 1;456:137-143. doi: 10.1016/j.cca.2016.02.027. Epub 2016 Mar 3.


Contribution of genomic copy-number variations in prenatal oral clefts: a multicenter cohort study.

Cao Y, Li Z, Rosenfeld JA, Pursley AN, Patel A, Huang J, Wang H, Chen M, Sun X, Leung TY, Cheung SW, Choy KW.

Genet Med. 2016 Oct;18(10):1052-5. doi: 10.1038/gim.2015.216. Epub 2016 Feb 25.


Effect of pregnancy on the activity and infectivity of hepatitis B virus in women with chronic hepatitis B infection.

Lao TT, Leung TY, Chan HL, Wong VW.

Hong Kong Med J. 2015 Dec;21 Suppl 7:S4-7. No abstract available.


Ultrasound-Guided Percutaneous Embolisation of Placental Chorioangioma Using Cyanoacrylate.

Cheng YK, Yu SC, So PL, Leung TY.

Fetal Diagn Ther. 2017;41(1):76-79. doi: 10.1159/000442586. Epub 2016 Jan 5.


FIGO consensus guidelines on intrapartum fetal monitoring: Adjunctive technologies.

Visser GH, Ayres-de-Campos D; FIGO Intrapartum Fetal Monitoring Expert Consensus Panel.

Int J Gynaecol Obstet. 2015 Oct;131(1):25-9. doi: 10.1016/j.ijgo.2015.06.021. No abstract available.


FIGO consensus guidelines on intrapartum fetal monitoring: Cardiotocography.

Ayres-de-Campos D, Spong CY, Chandraharan E; FIGO Intrapartum Fetal Monitoring Expert Consensus Panel.

Int J Gynaecol Obstet. 2015 Oct;131(1):13-24. doi: 10.1016/j.ijgo.2015.06.020. No abstract available.


FIGO consensus guidelines on intrapartum fetal monitoring: Intermittent auscultation.

Lewis D, Downe S; FIGO Intrapartum Fetal Monitoring Expert Consensus Panel.

Int J Gynaecol Obstet. 2015 Oct;131(1):9-12. doi: 10.1016/j.ijgo.2015.06.019. No abstract available.


FIGO consensus guidelines on intrapartum fetal monitoring: Physiology of fetal oxygenation and the main goals of intrapartum fetal monitoring.

Ayres-de-Campos D, Arulkumaran S; FIGO Intrapartum Fetal Monitoring Expert Consensus Panel.

Int J Gynaecol Obstet. 2015 Oct;131(1):5-8. doi: 10.1016/j.ijgo.2015.06.018. No abstract available.


FIGO consensus guidelines on intrapartum fetal monitoring: Introduction.

Ayres-de-Campos D, Arulkumaran S; FIGO Intrapartum Fetal Monitoring Expert Consensus Panel.

Int J Gynaecol Obstet. 2015 Oct;131(1):3-4. doi: 10.1016/j.ijgo.2015.06.017. No abstract available.


Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

Sun K, Jiang P, Chan KC, Wong J, Cheng YK, Liang RH, Chan WK, Ma ES, Chan SL, Cheng SH, Chan RW, Tong YK, Ng SS, Wong RS, Hui DS, Leung TN, Leung TY, Lai PB, Chiu RW, Lo YM.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5503-12. doi: 10.1073/pnas.1508736112. Epub 2015 Sep 21.


Noninvasive prenatal testing by nanopore sequencing of maternal plasma DNA: feasibility assessment.

Cheng SH, Jiang P, Sun K, Cheng YK, Chan KC, Leung TY, Chiu RW, Lo YM.

Clin Chem. 2015 Oct;61(10):1305-6. doi: 10.1373/clinchem.2015.245076. Epub 2015 Aug 18. No abstract available.


Rubella seronegativity in antenatal screening - Is it influenced by the introduction of universal childhood rubella immunization?

Lao TT, Sahota DS, Law LW, Leung TY.

Vaccine. 2015 Sep 11;33(38):4776-81. doi: 10.1016/j.vaccine.2015.07.105. Epub 2015 Aug 10.


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