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Items: 1 to 50 of 274

1.

Silencing Stem Cell Factor Gene in Fibroblasts to Regulate Paracrine Factor Productions and Enhance c-Kit Expression in Melanocytes on Melanogenesis.

Li PH, Liu LH, Chang CC, Gao R, Leung CH, Ma DL, David Wang HM.

Int J Mol Sci. 2018 May 16;19(5). pii: E1475. doi: 10.3390/ijms19051475.

2.

Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex.

Vellaisamy K, Li G, Ko CN, Zhong HJ, Fatima S, Kwan HY, Wong CY, Kwong WJ, Tan W, Leung CH, Ma DL.

Chem Sci. 2017 Dec 19;9(5):1119-1125. doi: 10.1039/c7sc04798c. eCollection 2018 Feb 7.

3.

Fracture risk prediction using FRAX in patients following hematopoietic stem cell transplantation.

Pundole X, Murphy WA, Ebede CC, Karim E, Manocha S, Don-Pedro D, Rondon G, Leung CH, Liu S, Du XL, Champlin RE, Lu H.

Arch Osteoporos. 2018 Apr 4;13(1):38. doi: 10.1007/s11657-018-0453-5.

PMID:
29619576
4.

Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients.

Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES.

Mol Cancer Ther. 2018 Mar 28. doi: 10.1158/1535-7163.MCT-17-0901. [Epub ahead of print]

PMID:
29592877
5.

Hemorrhagic Shock/Resuscitation Reduces the M2 Phenotype of Alveolar Macrophages: A Potential Mechanism Contributing to Increased LPS-Induced Lung Injury.

Safavian D, Leung CH, Kapus A, Ailenberg M, Szaszi K, Shani R, Di Ciano-Oliveira C, Ghazerian M, Rotstein O.

Shock. 2018 Feb 27. doi: 10.1097/SHK.0000000000001135. [Epub ahead of print]

PMID:
29489738
6.

Identification of a rhodium(iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells.

Yang GJ, Zhong HJ, Ko CN, Wong SY, Vellaisamy K, Ye M, Ma DL, Leung CH.

Chem Commun (Camb). 2018 Mar 6;54(20):2463-2466. doi: 10.1039/c7cc09384e.

PMID:
29367998
7.

Small Molecule Pin1 Inhibitor Blocking NF-κB Signaling in Prostate Cancer Cells.

Wu KJ, Zhong HJ, Yang G, Wu C, Huang JM, Li G, Ma DL, Leung CH.

Chem Asian J. 2018 Feb 2;13(3):275-279. doi: 10.1002/asia.201701216. Epub 2018 Jan 15.

PMID:
29288531
8.

Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing.

Wu KJ, Zhong HJ, Li G, Liu C, Wang HD, Ma DL, Leung CH.

Eur J Med Chem. 2018 Jan 1;143:1021-1027. doi: 10.1016/j.ejmech.2017.11.101. Epub 2017 Dec 6.

PMID:
29232579
9.

Clinical Activity of Pazopanib in Patients with Advanced Desmoplastic Small Round Cell Tumor.

Menegaz BA, Cuglievan B, Benson J, Camacho P, Lamhamedi-Cherradi SE, Leung CH, Warneke CL, Huh W, Subbiah V, Benjamin RS, Patel S, Daw N, Hayes-Jordan A, Ludwig JA.

Oncologist. 2018 Mar;23(3):360-366. doi: 10.1634/theoncologist.2017-0408. Epub 2017 Dec 6.

PMID:
29212731
10.

Real-time detection of oxalyl chloride based on a long-lived iridium(iii) probe.

Wu C, Li G, Han QB, Pei RJ, Liu JB, Ma DL, Leung CH.

Dalton Trans. 2017 Dec 12;46(48):17074-17079. doi: 10.1039/c7dt04054g.

PMID:
29188252
11.

Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity.

Ng SW, Chung LH, Yeung CF, Lo HS, Shek HL, Kang TS, Leung CH, Ma DL, Wong CY.

Chemistry. 2018 Feb 6;24(8):1779-1783. doi: 10.1002/chem.201705450. Epub 2017 Dec 7.

PMID:
29160601
12.

Ruling out dark matter interpretation of the galactic GeV excess by gamma-ray data of galaxy clusters.

Chan MH, Leung CH.

Sci Rep. 2017 Nov 2;7(1):14895. doi: 10.1038/s41598-017-14950-4.

13.

Development of a Long-Lived Luminescence Probe for Visualizing β-Galactosidase in Ovarian Carcinoma Cells.

Wang W, Vellaisamy K, Li G, Wu C, Ko CN, Leung CH, Ma DL.

Anal Chem. 2017 Nov 7;89(21):11679-11684. doi: 10.1021/acs.analchem.7b03114. Epub 2017 Oct 12.

PMID:
28969424
14.

Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(iii) metal-based compound.

Liu LJ, Wang W, Huang SY, Hong Y, Li G, Lin S, Tian J, Cai Z, Wang HD, Ma DL, Leung CH.

Chem Sci. 2017 Jul 1;8(7):4756-4763. doi: 10.1039/c7sc00311k. Epub 2017 May 16.

15.

Construction of a Nano Biosensor for Cyanide Anion Detection and Its Application in Environmental and Biological Systems.

Dong ZZ, Yang C, Vellaisamy K, Li G, Leung CH, Ma DL.

ACS Sens. 2017 Oct 27;2(10):1517-1522. doi: 10.1021/acssensors.7b00553. Epub 2017 Oct 5.

PMID:
28948760
16.

Risk factors for falls in older patients with cancer.

Zhang X, Sun M, Liu S, Leung CH, Pang L, Popat UR, Champlin R, Holmes HM, Valero V, Dinney CP, Tripathy D, Edwards BJ.

BMJ Support Palliat Care. 2018 Mar;8(1):34-37. doi: 10.1136/bmjspcare-2017-001388. Epub 2017 Aug 31.

PMID:
28860112
17.

A long-lived ferrocene-conjugated iridium(III) complex for sensitive turn-on luminescence detection of traces of DMSO in water and human serum.

Ko CN, Wu C, Li G, Leung CH, Liu JB, Ma DL.

Anal Chim Acta. 2017 Sep 1;984:193-201. doi: 10.1016/j.aca.2017.06.042. Epub 2017 Jun 30.

PMID:
28843564
18.

Turn-on Luminescent Probe for Hydrogen Peroxide Sensing and Imaging in Living Cells based on an Iridium(III) Complex-Silver Nanoparticle Platform.

Liu J, Dong ZZ, Yang C, Li G, Wu C, Lee FW, Leung CH, Ma DL.

Sci Rep. 2017 Aug 21;7(1):8980. doi: 10.1038/s41598-017-09478-6.

19.

A suspending-droplet mode paper-based microfluidic platform for low-cost, rapid, and convenient detection of lead(II) ions in liquid solution.

Sun H, Li W, Dong ZZ, Hu C, Leung CH, Ma DL, Ren K.

Biosens Bioelectron. 2018 Jan 15;99:361-367. doi: 10.1016/j.bios.2017.07.073. Epub 2017 Aug 1.

PMID:
28800508
20.

Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.

Panse G, Chrisinger JS, Leung CH, Ingram DR, Khan S, Wani K, Lin H, Lazar AJ, Wang WL.

Histopathology. 2018 Jan;72(2):239-247. doi: 10.1111/his.13337. Epub 2017 Oct 19.

PMID:
28796347
21.

Emergence of carbapenem-resistant Acinetobacter baumannii ST787 in clinical isolates from blood in a tertiary teaching hospital in Northern Taiwan.

Hu YF, Hou CJ, Kuo CF, Wang NY, Wu AY, Leung CH, Liu CP, Yeh HI.

J Microbiol Immunol Infect. 2017 Oct;50(5):640-645. doi: 10.1016/j.jmii.2016.08.025. Epub 2017 Jun 22.

22.

Recent development of transition metal complexes with in vivo antitumor activity.

Liang JX, Zhong HJ, Yang G, Vellaisamy K, Ma DL, Leung CH.

J Inorg Biochem. 2017 Dec;177:276-286. doi: 10.1016/j.jinorgbio.2017.06.002. Epub 2017 Jun 16.

PMID:
28641893
23.

Luminescent turn-on detection of Hg(II) via the quenching of an iridium(III) complex by Hg(II)-mediated silver nanoparticles.

Liu J, Vellaisamy K, Yang G, Leung CH, Ma DL.

Sci Rep. 2017 Jun 15;7(1):3620. doi: 10.1038/s41598-017-03952-x.

24.

Dipeptidyl Peptidase IV as a Prognostic Marker and Therapeutic Target in Papillary Thyroid Carcinoma.

Lee JJ, Wang TY, Liu CL, Chien MN, Chen MJ, Hsu YC, Leung CH, Cheng SP.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2930-2940. doi: 10.1210/jc.2017-00346.

PMID:
28575350
25.

Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications.

Ma DL, Lin S, Wang W, Yang C, Leung CH.

Chem Sci. 2017 Feb 1;8(2):878-889. doi: 10.1039/c6sc04175b. Epub 2016 Nov 2.

26.

A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells.

Wu KJ, Huang JM, Zhong HJ, Dong ZZ, Vellaisamy K, Lu JJ, Chen XP, Chiu P, Kwong DWJ, Han QB, Ma DL, Leung CH.

PLoS One. 2017 Jun 1;12(6):e0177123. doi: 10.1371/journal.pone.0177123. eCollection 2017.

27.

A reaction-based luminescent switch-on sensor for the detection of OH- ions in simulated wastewater.

Wu C, Vellaisamy K, Yang G, Dong ZZ, Leung CH, Liu JB, Ma DL.

Dalton Trans. 2017 May 23;46(20):6677-6682. doi: 10.1039/c7dt00633k.

PMID:
28484771
28.

The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances.

Ma DL, Wu C, Dong ZZ, Tam WS, Wong SW, Yang C, Li G, Leung CH.

Chem Asian J. 2017 Aug 4;12(15):1851-1860. doi: 10.1002/asia.201700533. Epub 2017 Jun 19. Review.

PMID:
28470784
29.

Luminescent Strategies for Label-Free G-Quadruplex-Based Enzyme Activity Sensing.

Ma DL, Dong ZZ, Vellaisamy K, Cheung KM, Yang G, Leung CH.

Chem Rec. 2017 Nov;17(11):1135-1145. doi: 10.1002/tcr.201700014. Epub 2017 May 3.

PMID:
28467681
30.

A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation.

Ko CN, Yang C, Lin S, Li S, Dong Z, Liu J, Lee SM, Leung CH, Ma DL.

Biosens Bioelectron. 2017 Aug 15;94:575-583. doi: 10.1016/j.bios.2017.03.050. Epub 2017 Mar 23.

PMID:
28364704
31.

An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB.

Kang TS, Wang W, Zhong HJ, Dong ZZ, Huang Q, Mok SW, Leung CH, Wong VK, Ma DL.

Cancer Lett. 2017 Jun 28;396:76-84. doi: 10.1016/j.canlet.2017.03.016. Epub 2017 Mar 18.

PMID:
28323031
32.

Medical student-led patient education prior to hospital discharge improves 1-month adherence rates.

Leung CH, Chong C, Lim WK.

Intern Med J. 2017 Mar;47(3):328-332. doi: 10.1111/imj.13365.

PMID:
28260252
33.

Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction.

Yang C, Wang W, Li GD, Zhong HJ, Dong ZZ, Wong CY, Kwong DW, Ma DL, Leung CH.

Sci Rep. 2017 Feb 22;7:42860. doi: 10.1038/srep42860.

34.

A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells.

Yang C, Wang W, Liang JX, Li G, Vellaisamy K, Wong CY, Ma DL, Leung CH.

J Med Chem. 2017 Mar 23;60(6):2597-2603. doi: 10.1021/acs.jmedchem.7b00133. Epub 2017 Mar 1.

PMID:
28219005
35.

First Synthesis of an Oridonin-Conjugated Iridium(III) Complex for the Intracellular Tracking of NF-κB in Living Cells.

Wang W, Yang C, Lin S, Vellaisamy K, Li G, Tan W, Leung CH, Ma DL.

Chemistry. 2017 Apr 6;23(20):4929-4935. doi: 10.1002/chem.201700770. Epub 2017 Mar 21.

PMID:
28211965
36.

A cyclometalated iridium(III) complex used as a conductor for the electrochemical sensing of IFN-γ.

Miao X, Ko CN, Vellaisamy K, Li Z, Yang G, Leung CH, Ma DL.

Sci Rep. 2017 Feb 15;7:42740. doi: 10.1038/srep42740.

37.

A MnO2 nanosheet-assisted GSH detection platform using an iridium(iii) complex as a switch-on luminescent probe.

Dong ZZ, Lu L, Ko CN, Yang C, Li S, Lee MY, Leung CH, Ma DL.

Nanoscale. 2017 Apr 6;9(14):4677-4682. doi: 10.1039/c6nr08357a.

PMID:
28139807
38.

Luminescent iridium(iii) complexes as COX-2-specific imaging agents in cancer cells.

Liu C, Yang C, Lu L, Wang W, Tan W, Leung CH, Ma DL.

Chem Commun (Camb). 2017 Mar 2;53(19):2822-2825. doi: 10.1039/c6cc08109f.

PMID:
28127603
39.

Anti-Fatigue Effects of the Unique Polysaccharide Marker of Dendrobium officinale on BALB/c Mice.

Wei W, Li ZP, Zhu T, Fung HY, Wong TL, Wen X, Ma DL, Leung CH, Han QB.

Molecules. 2017 Jan 18;22(1). pii: E155. doi: 10.3390/molecules22010155.

40.

Carrageenan activates monocytes via type-specific binding with interleukin-8: an implication for design of immuno-active biomaterials.

Chan WI, Zhang G, Li X, Leung CH, Ma DL, Dong L, Wang C.

Biomater Sci. 2017 Feb 28;5(3):403-407. doi: 10.1039/c6bm00799f.

PMID:
28106172
41.

Comprehensive Quantitative Analysis of 32 Chemical Ingredients of a Chinese Patented Drug Sanhuang Tablet.

Fung HY, Lang Y, Ho HM, Wong TL, Ma DL, Leung CH, Han QB.

Molecules. 2017 Jan 12;22(1). pii: E111. doi: 10.3390/molecules22010111.

42.

Baicalein Induces Beclin 1- and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells.

Wang YF, Xu YL, Tang ZH, Li T, Zhang LL, Chen X, Lu JH, Leung CH, Ma DL, Qiang WA, Wang YT, Lu JJ.

Am J Chin Med. 2017;45(1):123-136. doi: 10.1142/S0192415X17500094. Epub 2017 Jan 13.

PMID:
28081631
43.

Correction: Inhibition of TLR1/2 dimerization by enantiomers of metal complexes.

Liu LJ, Wang W, Zhong Z, Lin S, Lu L, Wang YT, Ma DL, Leung CH.

Chem Commun (Camb). 2017 Jan 19;53(7):1325. doi: 10.1039/c7cc90024d.

PMID:
28075430
44.

PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.

Niu Y, Sun W, Lu JJ, Ma DL, Leung CH, Pei L, Chen X.

Oxid Med Cell Longev. 2016;2016:4313204. doi: 10.1155/2016/4313204. Epub 2016 Nov 30.

45.

The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours.

Panse G, Leung CH, Ingram DR, Wani K, Torres KE, Lin H, Lazar AJ, Wang WL.

Histopathology. 2017 May;70(6):946-953. doi: 10.1111/his.13154. Epub 2017 Feb 9.

PMID:
27992966
46.

A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease.

Zhong HJ, Wang W, Kang TS, Yan H, Yang Y, Xu L, Wang Y, Ma DL, Leung CH.

J Med Chem. 2017 Jan 12;60(1):497-503. doi: 10.1021/acs.jmedchem.6b00250. Epub 2016 Dec 23.

PMID:
27976900
47.
48.

A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity.

Kang TS, Wang W, Zhong HJ, Liang JX, Ko CN, Lu JJ, Chen XP, Ma DL, Leung CH.

Biochim Biophys Acta. 2017 Feb;1861(2):256-263. doi: 10.1016/j.bbagen.2016.11.032. Epub 2016 Nov 23.

PMID:
27888146
49.

An Ir(III) complex chemosensor for the detection of thiols.

Mao Z, Liu J, Kang TS, Wang W, Han QB, Wang CM, Leung CH, Ma DL.

Sci Technol Adv Mater. 2016 Apr 6;17(1):109-114. eCollection 2016.

50.

A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T-Hg2+-T mismatched DNA.

Wang W, Kang TS, Chan PW, Lu JJ, Chen XP, Leung CH, Ma DL.

Sci Technol Adv Mater. 2015 Nov 17;16(6):065004. eCollection 2015 Dec.

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