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Items: 1 to 50 of 498

1.

Centennial perspective on human adaptability.

Leonard WR.

Am J Phys Anthropol. 2018 Apr;165(4):813-833. doi: 10.1002/ajpa.23401. No abstract available.

PMID:
29574834
2.

Sex, drugs and social connectedness: wellbeing among HIV-positive gay and bisexual men who use party-and-play drugs.

Power J, Mikołajczak G, Bourne A, Brown G, Leonard W, Lyons A, Dowsett GW, Lucke J.

Sex Health. 2018 Mar 16. doi: 10.1071/SH17151. [Epub ahead of print]

PMID:
29544599
3.

TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state.

Rochman Y, Dienger-Stambaugh K, Richgels PK, Lewkowich IP, Kartashov AV, Barski A, Khurana Hershey GK, Leonard WJ, Singh H.

Sci Signal. 2018 Mar 13;11(521). pii: eaam8858. doi: 10.1126/scisignal.aam8858.

PMID:
29535264
4.

Biology of IL-2 and its therapeutic modulation: Mechanisms and strategies.

Mitra S, Leonard WJ.

J Leukoc Biol. 2018 Apr;103(4):643-655. doi: 10.1002/JLB.2RI0717-278R. Epub 2018 Mar 9. Review.

PMID:
29522246
5.

All-Trans Retinoic Acid Enhances Antibody Production by Inducing the Expression of Thymic Stromal Lymphopoietin Protein.

Hatayama T, Segawa R, Mizuno N, Eguchi S, Akamatsu H, Fukuda M, Nakata F, Leonard WJ, Hiratsuka M, Hirasawa N.

J Immunol. 2018 Apr 15;200(8):2670-2676. doi: 10.4049/jimmunol.1701276. Epub 2018 Mar 2.

PMID:
29500243
6.

Improving alcohol and mental health treatment for lesbian, bisexual and queer women: Identity matters.

Pennay A, McNair R, Hughes TL, Leonard W, Brown R, Lubman DI.

Aust N Z J Public Health. 2018 Feb;42(1):35-42. doi: 10.1111/1753-6405.12739. Epub 2017 Dec 13.

PMID:
29235690
7.

The γ c family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response.

Spolski R, Gromer D, Leonard WJ.

F1000Res. 2017 Oct 23;6:1872. doi: 10.12688/f1000research.12202.1. eCollection 2017. Review.

8.

Diet, atherosclerosis, and helmintic infection in Tsimane.

Masterson EE, Leonard WR, Hujoel PP.

Lancet. 2017 Nov 4;390(10107):2034-2035. doi: 10.1016/S0140-6736(17)31945-1. No abstract available.

PMID:
29115238
9.

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.

Lin JX, Du N, Li P, Kazemian M, Gebregiorgis T, Spolski R, Leonard WJ.

Nat Commun. 2017 Nov 6;8(1):1320. doi: 10.1038/s41467-017-01477-5.

10.

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus.

Li P, Mitra S, Spolski R, Oh J, Liao W, Tang Z, Mo F, Li X, West EE, Gromer D, Lin JX, Liu C, Ruan Y, Leonard WJ.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12111-12119. doi: 10.1073/pnas.1714019114. Epub 2017 Oct 24.

PMID:
29078395
11.

The Common Cytokine Receptor γ Chain Family of Cytokines.

Lin JX, Leonard WJ.

Cold Spring Harb Perspect Biol. 2017 Oct 16. pii: a028449. doi: 10.1101/cshperspect.a028449. [Epub ahead of print]

PMID:
29038115
12.

Child stunting is associated with weaker human capital among native Amazonians.

Undurraga EA, Behrman JR, Emmett SD, Kidd C, Leonard WR, Piantadosi ST, Reyes-García V, Sharma A, Zhang R, Godoy RA.

Am J Hum Biol. 2018 Jan;30(1). doi: 10.1002/ajhb.23059. Epub 2017 Sep 13.

PMID:
28901592
13.

Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory.

Shin HM, Kapoor VN, Kim G, Li P, Kim HR, Suresh M, Kaech SM, Wherry EJ, Selin LK, Leonard WJ, Welsh RM, Berg LJ.

PLoS Pathog. 2017 Aug 21;13(8):e1006544. doi: 10.1371/journal.ppat.1006544. eCollection 2017 Aug.

14.

A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus.

West EE, Spolski R, Kazemian M, Yu ZX, Kemper C, Leonard WJ.

Sci Immunol. 2016 Nov 18;1(5). pii: eaaf8471. doi: 10.1126/sciimmunol.aaf8471.

PMID:
28783679
15.

Genetic background-dependent role of Egr1 for eyelid development.

Oh J, Wang Y, Chen S, Li P, Du N, Yu ZX, Butcher D, Gebregiorgis T, Strachan E, Lehmann OJ, Brooks BP, Chan CC, Leonard WJ.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7131-E7139. doi: 10.1073/pnas.1705848114. Epub 2017 Aug 4.

16.

Skin-derived TSLP systemically expands regulatory T cells.

Leichner TM, Satake A, Harrison VS, Tanaka Y, Archambault AS, Kim BS, Siracusa MC, Leonard WJ, Naji A, Wu GF, Artis D, Kambayashi T.

J Autoimmun. 2017 May;79:39-52. doi: 10.1016/j.jaut.2017.01.003. Epub 2017 Jan 23.

PMID:
28126203
17.

Stigma, gay men and biomedical prevention: the challenges and opportunities of a rapidly changing HIV prevention landscape.

Brown G, Leonard W, Lyons A, Power J, Sander D, McColl W, Johnson R, James C, Hodson M, Carman M.

Sex Health. 2017 Feb;14(1):111-118. doi: 10.1071/SH16052.

PMID:
27977386
18.

Response to commentary regarding the article: "Lifestyle mediates seasonal changes in metabolic health among the Yakut (Sakha) of Northeastern Siberia".

Levy SB, Leonard WR.

Am J Hum Biol. 2016 Nov;28(6):956. doi: 10.1002/ajhb.22926. Epub 2016 Nov 3. No abstract available.

PMID:
27807904
19.

Sympathetic Innervation of Cold-Activated Brown and White Fat in Lean Young Adults.

Muzik O, Mangner TJ, Leonard WR, Kumar A, Granneman JG.

J Nucl Med. 2017 May;58(5):799-806. doi: 10.2967/jnumed.116.180992. Epub 2016 Oct 27.

20.

Immunology: JAK3 inhibition—is it sufficient?

Leonard WJ, Mitra S, Lin JX.

Nat Chem Biol. 2016 May;12(5):308-10. No abstract available.

PMID:
27556128
21.

Molecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding Sites.

Sathyanarayana BK, Li P, Lin JX, Leonard WJ, Lee B.

PLoS One. 2016 Aug 18;11(8):e0160339. doi: 10.1371/journal.pone.0160339. eCollection 2016.

22.

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.

Sakuraba K, Oyamada A, Fujimura K, Spolski R, Iwamoto Y, Leonard WJ, Yoshikai Y, Yamada H.

Arthritis Res Ther. 2016 Aug 17;18:188. doi: 10.1186/s13075-016-1086-y.

23.

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP.

J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18.

24.

Gender-specific health implications of minority stress among lesbians and gay men.

Bariola E, Lyons A, Leonard W.

Aust N Z J Public Health. 2016 Dec;40(6):506-512. doi: 10.1111/1753-6405.12539. Epub 2016 Jul 3.

PMID:
27372452
25.

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.

26.

Lifestyle mediates seasonal changes in metabolic health among the yakut (sakha) of northeastern siberia.

Levy SB, Leonard WR, Tarskaia LA, Klimova TM, Fedorova VI, Baltakhinova ME, Josh Snodgrass J.

Am J Hum Biol. 2016 Nov;28(6):868-878. doi: 10.1002/ajhb.22879. Epub 2016 Jun 13.

PMID:
27292232
27.

Catch-up growth and growth deficits: Nine-year annual panel child growth for native Amazonians in Bolivia.

Zhang R, Undurraga EA, Zeng W, Reyes-García V, Tanner S, Leonard WR, Behrman JR, Godoy RA.

Ann Hum Biol. 2016 Jul;43(4):304-15. doi: 10.1080/03014460.2016.1197312. Epub 2016 Jun 29.

28.

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.

Roychoudhuri R, Clever D, Li P, Wakabayashi Y, Quinn KM, Klebanoff CA, Ji Y, Sukumar M, Eil RL, Yu Z, Spolski R, Palmer DC, Pan JH, Patel SJ, Macallan DC, Fabozzi G, Shih HY, Kanno Y, Muto A, Zhu J, Gattinoni L, O'Shea JJ, Okkenhaug K, Igarashi K, Leonard WJ, Restifo NP.

Nat Immunol. 2016 Jul;17(7):851-860. doi: 10.1038/ni.3441. Epub 2016 May 9.

29.

William E. Paul, MD (1936-2015).

Germain RN, Fowlkes BJ, Samelson LE, Leonard WJ.

Trends Immunol. 2015 Dec;36(12):751-3. No abstract available.

PMID:
27064162
30.

IL-21 Signaling in Immunity.

Leonard WJ, Wan CK.

F1000Res. 2016 Feb 26;5. pii: F1000 Faculty Rev-224. doi: 10.12688/f1000research.7634.1. eCollection 2016. Review.

31.

A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

Xin A, Masson F, Liao Y, Preston S, Guan T, Gloury R, Olshansky M, Lin JX, Li P, Speed TP, Smyth GK, Ernst M, Leonard WJ, Pellegrini M, Kaech SM, Nutt SL, Shi W, Belz GT, Kallies A.

Nat Immunol. 2016 Apr;17(4):422-32. doi: 10.1038/ni.3410. Epub 2016 Mar 7.

32.

Myeloid-derived suppressor cells reveal radioprotective properties through arginase-induced l-arginine depletion.

Leonard W, Dufait I, Schwarze JK, Law K, Engels B, Jiang H, Van den Berge D, Gevaert T, Storme G, Verovski V, Breckpot K, De Ridder M.

Radiother Oncol. 2016 May;119(2):291-9. doi: 10.1016/j.radonc.2016.01.014. Epub 2016 Feb 10.

PMID:
26874542
33.

Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.

Yan M, Wang H, Sun J, Liao W, Li P, Zhu Y, Xu C, Joo J, Sun Y, Abbasi S, Kovalchuk A, Lv N, Leonard WJ, Morse HC 3rd.

J Immunol. 2016 Mar 1;196(5):1999-2003. doi: 10.4049/jimmunol.1500766. Epub 2016 Feb 3.

34.

T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite.

Ballesteros-Tato A, Randall TD, Lund FE, Spolski R, Leonard WJ, León B.

Immunity. 2016 Feb 16;44(2):259-73. doi: 10.1016/j.immuni.2015.11.017. Epub 2016 Jan 26.

35.

William E. Paul, M.D. (1936–2015).

Germain RN, Fowlkes BJ, Samelson LE, Leonard WJ.

Immunity. 2015 Oct 20;43(4):617-9. No abstract available.

36.

The effects of community income inequality on health: Evidence from a randomized control trial in the Bolivian Amazon.

Undurraga EA, Behrman JR, Leonard WR, Godoy RA.

Soc Sci Med. 2016 Jan;149:66-75. doi: 10.1016/j.socscimed.2015.12.003. Epub 2015 Dec 9.

37.

Endothelial interleukin-21 receptor up-regulation in peripheral artery disease.

Wang T, Cunningham A, Houston K, Sharma AM, Chen L, Dokun AO, Lye RJ, Spolski R, Leonard WJ, Annex BH.

Vasc Med. 2016 Apr;21(2):99-104. doi: 10.1177/1358863X15621798. Epub 2015 Dec 24.

38.

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.

Sukumar M, Liu J, Mehta GU, Patel SJ, Roychoudhuri R, Crompton JG, Klebanoff CA, Ji Y, Li P, Yu Z, Whitehill GD, Clever D, Eil RL, Palmer DC, Mitra S, Rao M, Keyvanfar K, Schrump DS, Wang E, Marincola FM, Gattinoni L, Leonard WJ, Muranski P, Finkel T, Restifo NP.

Cell Metab. 2016 Jan 12;23(1):63-76. doi: 10.1016/j.cmet.2015.11.002. Epub 2015 Dec 8.

39.

Cutting Edge: IL-1 Receptor Signaling is Critical for the Development of Autoimmune Uveitis.

Wan CK, He C, Sun L, Egwuagu CE, Leonard WJ.

J Immunol. 2016 Jan 15;196(2):543-6. doi: 10.4049/jimmunol.1502080. Epub 2015 Dec 7.

40.

Adiponectin, hemoglobin, and cardiovascular risk in an indigenous siberian population.

Streeter EA, Squires EC, Leonard WR, Tarskaia LA, Klimova TM, Fedorova VI, Baltakhinova ME, Krivoshapkin VG, Snodgrass JJ.

Am J Hum Biol. 2016 Jul;28(4):580-3. doi: 10.1002/ajhb.22808. Epub 2015 Nov 23.

PMID:
26593323
41.

A model for lesbian, bisexual and queer-related influences on alcohol consumption and implications for policy and practice.

McNair R, Pennay A, Hughes T, Brown R, Leonard W, Lubman DI.

Cult Health Sex. 2016;18(4):405-21. doi: 10.1080/13691058.2015.1089602. Epub 2015 Oct 14.

PMID:
26466746
42.

The mental health benefits of relationship formalisation among lesbians and gay men in same-sex relationships.

Bariola E, Lyons A, Leonard W.

Aust N Z J Public Health. 2015 Dec;39(6):530-5. doi: 10.1111/1753-6405.12432. Epub 2015 Sep 3.

PMID:
26337174
43.

The Tsimane' Amazonian Panel Study (TAPS): Nine years (2002-2010) of annual data available to the public.

Leonard WR, Reyes-García V, Tanner S, Rosinger A, Schultz A, Vadez V, Zhang R, Godoy R.

Econ Hum Biol. 2015 Dec;19:51-61. doi: 10.1016/j.ehb.2015.07.004. Epub 2015 Aug 2.

44.

Demographic and Psychosocial Factors Associated With Psychological Distress and Resilience Among Transgender Individuals.

Bariola E, Lyons A, Leonard W, Pitts M, Badcock P, Couch M.

Am J Public Health. 2015 Oct;105(10):2108-16. doi: 10.2105/AJPH.2015.302763. Epub 2015 Aug 13.

45.

IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells.

Wan CK, Li P, Spolski R, Oh J, Andraski AB, Du N, Yu ZX, Dillon CP, Green DR, Leonard WJ.

Nat Commun. 2015 Aug 13;6:7988. doi: 10.1038/ncomms8988.

46.

Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer.

Kazemian M, Ren M, Lin JX, Liao W, Spolski R, Leonard WJ.

Mol Syst Biol. 2015 Aug 7;11(8):826. doi: 10.15252/msb.156172.

47.

Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells.

Wan CK, Andraski AB, Spolski R, Li P, Kazemian M, Oh J, Samsel L, Swanson PA 2nd, McGavern DB, Sampaio EP, Freeman AF, Milner JD, Holland SM, Leonard WJ.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9394-9. doi: 10.1073/pnas.1511711112. Epub 2015 Jul 13.

48.

Possible Human Papillomavirus 38 Contamination of Endometrial Cancer RNA Sequencing Samples in The Cancer Genome Atlas Database.

Kazemian M, Ren M, Lin JX, Liao W, Spolski R, Leonard WJ.

J Virol. 2015 Sep;89(17):8967-73. doi: 10.1128/JVI.00822-15. Epub 2015 Jun 17.

49.

Socio-demographic predictors of sleep complaints in indigenous Siberians with a mixed economy.

Wilson HJ, Klimova TM, Knuston KL, Fedorova VI, Fedorov A, Yegorovna BM, Leonard WR.

Am J Phys Anthropol. 2015 Aug;157(4):641-7. doi: 10.1002/ajpa.22761. Epub 2015 Jun 8.

50.

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ.

Immunity. 2015 May 19;42(5):826-38. doi: 10.1016/j.immuni.2015.04.018.

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