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Excessive interferon-α signaling in autoimmunity alters glycosphingolipid processing in B cells.

Tan AH, Sanny A, Ng SW, Ho YS, Basri N, Lee AP, Lam KP.

J Autoimmun. 2017 Nov 27. pii: S0896-8411(17)30603-0. doi: 10.1016/j.jaut.2017.11.004. [Epub ahead of print]


Underestimation of Risk of Carotid Subclinical Atherosclerosis by Cardiovascular Risk Scores in Patients with Psoriatic Arthritis.

Shen J, Lam SH, Shang Q, Wong CK, Li EK, Wong P, Kun EW, Cheng IT, Li M, Li TK, Zhu TY, Lee JJ, Chang M, Lee AP, Tam LS.

J Rheumatol. 2018 Feb;45(2):218-226. doi: 10.3899/jrheum.170025. Epub 2017 Nov 15.


High-efficiency single cell encapsulation and size selective capture of cells in picoliter droplets based on hydrodynamic micro-vortices.

Kamalakshakurup G, Lee AP.

Lab Chip. 2017 Dec 5;17(24):4324-4333. doi: 10.1039/c7lc00972k.


Does Kidney Donor Risk Index implementation lead to the transplantation of more and higher-quality donor kidneys?

Philipse E, Lee APK, Bracke B, Hartman V, Chapelle T, Roeyen G, de Greef K, Ysebaert DK, van Beeumen G, Couttenye MM, Van Craenenbroeck AH, Hellemans R, Bosmans JL, Abramowicz D.

Nephrol Dial Transplant. 2017 Nov 1;32(11):1934-1938. doi: 10.1093/ndt/gfx257.


Acute hantavirus infection presenting as haemolytic-uraemic syndrome (HUS): the importance of early clinical diagnosis.

Clement J, Lee APK, Verpooten GA, Laenen L, Vergote V, De Samblanx H, Berneman ZN, Van Ranst M, Maes P.

Eur J Clin Microbiol Infect Dis. 2018 Jan;37(1):135-140. doi: 10.1007/s10096-017-3113-6. Epub 2017 Oct 6.


Automated left heart chamber volumetric assessment using three-dimensional echocardiography in Chinese adolescents.

Luo XX, Fang F, So HK, Liu C, Yam MC, Lee AP.

Echo Res Pract. 2017 Dec;4(4):53-61. doi: 10.1530/ERP-17-0028. Epub 2017 Sep 1.


Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study.

Lee AP, Mulligan K, Schambelan M, Murphy EJ, Weiss EJ.

F1000Res. 2017 May 3;6:614. doi: 10.12688/f1000research.11359.1. eCollection 2017.


Pharmacokinetics of MHAA4549A, an Anti-Influenza A Monoclonal Antibody, in Healthy Subjects Challenged with Influenza A Virus in a Phase IIa Randomized Trial.

Deng R, Lee AP, Maia M, Lim JJ, Burgess T, Horn P, Derby MA, Newton E, Tavel JA, Hanley WD.

Clin Pharmacokinet. 2018 Mar;57(3):367-377. doi: 10.1007/s40262-017-0564-y.


3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.

Wang X, Phan DTT, George SC, Hughes CCW, Lee AP.

Methods Mol Biol. 2017;1612:325-344. doi: 10.1007/978-1-4939-7021-6_24.


A high throughput microfluidic platform for size-selective enrichment of cell populations in tissue and blood samples.

Nivedita N, Garg N, Lee AP, Papautsky I.

Analyst. 2017 Jul 10;142(14):2558-2569. doi: 10.1039/c7an00290d.


Functional Implication of Mitral Annular Disjunction in Mitral Valve Prolapse: A Quantitative Dynamic 3D Echocardiographic Study.

Lee AP, Jin CN, Fan Y, Wong RHL, Underwood MJ, Wan S.

JACC Cardiovasc Imaging. 2017 Dec;10(12):1424-1433. doi: 10.1016/j.jcmg.2016.11.022. Epub 2017 May 17.


Using Multimaterial 3-Dimensional Printing for Personalized Planning of Complex Structural Heart Disease Intervention.

So KC, Fan Y, Sze L, Kwok KW, Chan AK, Cheung GS, Lee AP.

JACC Cardiovasc Interv. 2017 Jun 12;10(11):e97-e98. doi: 10.1016/j.jcin.2017.02.045. Epub 2017 May 17. No abstract available.


Transcatheter aortic valve implantation: the transaortic approach.

Chow SC, Cheung GS, Lee AP, Wu EB, Ho JY, Kwok MW, Yu PS, Wan IY, Underwood MJ, Wong RH.

Asian Cardiovasc Thorac Ann. 2017 Jun;25(5):357-363. doi: 10.1177/0218492317702027. Epub 2017 May 17.


Pharmacodynamics of remifentanil. Induced intracranial spike activity in mesial temporal lobe epilepsy.

Kjaer TW, Hogenhaven H, Lee AP, Madsen FF, Jespersen B, Brennum J, Derm L, Moltke FB.

Epilepsy Res. 2017 Jul;133:41-45. doi: 10.1016/j.eplepsyres.2017.03.008. Epub 2017 Mar 31.


In situ mRNA isolation from a microfluidic single-cell array using an external AFM nanoprobe.

Li X, Tao Y, Lee DH, Wickramasinghe HK, Lee AP.

Lab Chip. 2017 May 2;17(9):1635-1644. doi: 10.1039/c7lc00133a.


In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA).

Billones JB, Carrillo MC, Organo VG, Sy JB, Clavio NA, Macalino SJ, Emnacen IA, Lee AP, Ko PK, Concepcion GP.

Drug Des Devel Ther. 2017 Mar 2;11:563-574. doi: 10.2147/DDDT.S119930. eCollection 2017.


A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.

Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW.

Lab Chip. 2017 Jan 31;17(3):511-520. doi: 10.1039/c6lc01422d.


The influence of ultra-pasteurization by indirect heating versus direct steam injection on skim and 2% fat milks.

Lee AP, Barbano DM, Drake MA.

J Dairy Sci. 2017 Mar;100(3):1688-1701. doi: 10.3168/jds.2016-11899. Epub 2017 Jan 11.


Increased prevalence of coronary plaque in patients with psoriatic arthritis without prior diagnosis of coronary artery disease.

Shen J, Wong KT, Cheng IT, Shang Q, Li EK, Wong P, Kun EW, Law MY, Yip R, Yim I, Ying S, Li M, Li TK, Wong CK, Zhu TY, Lee JJ, Chang M, Lee AP, Tam LS.

Ann Rheum Dis. 2017 Jul;76(7):1237-1244. doi: 10.1136/annrheumdis-2016-210390. Epub 2017 Jan 4.


The seahorse genome and the evolution of its specialized morphology.

Lin Q, Fan S, Zhang Y, Xu M, Zhang H, Yang Y, Lee AP, Woltering JM, Ravi V, Gunter HM, Luo W, Gao Z, Lim ZW, Qin G, Schneider RF, Wang X, Xiong P, Li G, Wang K, Min J, Zhang C, Qiu Y, Bai J, He W, Bian C, Zhang X, Shan D, Qu H, Sun Y, Gao Q, Huang L, Shi Q, Meyer A, Venkatesh B.

Nature. 2016 Dec 14;540(7633):395-399. doi: 10.1038/nature20595.


Short communication: The effect of raw milk cooling on sensory perception and shelf life of high-temperature, short-time (HTST)-pasteurized skim milk.

Lee AP, Barbano DM, Drake MA.

J Dairy Sci. 2016 Dec;99(12):9659-9667. doi: 10.3168/jds.2016-11771. Epub 2016 Oct 13.


The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate.

Pan H, Yu H, Ravi V, Li C, Lee AP, Lian MM, Tay BH, Brenner S, Wang J, Yang H, Zhang G, Venkatesh B.

Gigascience. 2016 Sep 9;5(1):36. doi: 10.1186/s13742-016-0144-3.


3D microtumors in vitro supported by perfused vascular networks.

Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC.

Sci Rep. 2016 Aug 23;6:31589. doi: 10.1038/srep31589.


Contrast-Enhanced Transthoracic Aortic Ultrasonography for Endoleak Detection After Thoracic Endovascular Aortic Repair.

Lee AP, Wong RH, Underwood MJ, Yu SC.

Ann Thorac Surg. 2016 Sep;102(3):e261. doi: 10.1016/j.athoracsur.2016.03.056. No abstract available.


Using Anatomic Intelligence to Localize Mitral Valve Prolapse on Three-Dimensional Echocardiography.

Jin CN, Salgo IS, Schneider RJ, Kam KK, Chi WK, So CY, Tang Z, Wan S, Wong R, Underwood M, Lee AP.

J Am Soc Echocardiogr. 2016 Oct;29(10):938-945. doi: 10.1016/j.echo.2016.07.002. Epub 2016 Aug 18.


Impact of Intramyocardial Hemorrhage and Microvascular Obstruction on Cardiac Mechanics in Reperfusion Injury: A Speckle-Tracking Echocardiographic Study.

Zhao H, Lee AP, Li Z, Qiao Z, Fan Y, An D, Xu J, Pu J, Shen X, Ge H, He B.

J Am Soc Echocardiogr. 2016 Oct;29(10):973-982. doi: 10.1016/j.echo.2016.06.011. Epub 2016 Aug 11.


Mitral valve repair using a semirigid ring: patient selection and early outcomes.

Wan S, Lee AP, Attaran S, Yu PS, Au SS, Kwok MW, Lau RW, Wong RH, Wan IY, Ng SK, Underwood MJ.

Asian Cardiovasc Thorac Ann. 2016 Sep;24(7):647-52. doi: 10.1177/0218492316659970. Epub 2016 Jul 21.


How does an integrated primary care approach for patients in deprived neighbourhoods impact utilization patterns? An explorative study.

Kringos DS, van den Broeke JR, van der Lee AP, Plochg T, Stronks K.

BMC Public Health. 2016 Jul 11;16:545. doi: 10.1186/s12889-016-3246-z.


Electrophysiological Mechanisms of Gastrointestinal Arrhythmogenesis: Lessons from the Heart.

Tse G, Lai ET, Lee AP, Yan BP, Wong SH.

Front Physiol. 2016 Jun 14;7:230. doi: 10.3389/fphys.2016.00230. eCollection 2016. Review.


Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T, Chalopin D, Fan S, Wcisel D, Cañestro C, Sydes J, Beaudry FE, Sun Y, Hertel J, Beam MJ, Fasold M, Ishiyama M, Johnson J, Kehr S, Lara M, Letaw JH, Litman GW, Litman RT, Mikami M, Ota T, Saha NR, Williams L, Stadler PF, Wang H, Taylor JS, Fontenot Q, Ferrara A, Searle SM, Aken B, Yandell M, Schneider I, Yoder JA, Volff JN, Meyer A, Amemiya CT, Venkatesh B, Holland PW, Guiguen Y, Bobe J, Shubin NH, Di Palma F, Alfo Ldi J, Lindblad-Toh K, Postlethwait JH.

Nat Genet. 2016 May 27;48(6):700. doi: 10.1038/ng0616-700c. No abstract available.


[Health care usage by minimum income citizens in Amsterdam; a cross-sectional study into claims within the Dutch basic health insurance scheme].

Dijkshoorn H, Hazeleger FG, de Jong IM, van der Lee AP, Kunst AE.

Ned Tijdschr Geneeskd. 2016;160(0):A9816. Dutch.


Prevalence of atrial septal pouch and risk of ischemic stroke.

Sun JP, Meng F, Yang XS, Lee AP, Chen M, Zhang B, Yu CM.

Int J Cardiol. 2016 Jul 1;214:37-40. doi: 10.1016/j.ijcard.2016.03.119. Epub 2016 Mar 24.


The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T, Chalopin D, Fan S, Wcisel D, Cañestro C, Sydes J, Beaudry FE, Sun Y, Hertel J, Beam MJ, Fasold M, Ishiyama M, Johnson J, Kehr S, Lara M, Letaw JH, Litman GW, Litman RT, Mikami M, Ota T, Saha NR, Williams L, Stadler PF, Wang H, Taylor JS, Fontenot Q, Ferrara A, Searle SM, Aken B, Yandell M, Schneider I, Yoder JA, Volff JN, Meyer A, Amemiya CT, Venkatesh B, Holland PW, Guiguen Y, Bobe J, Shubin NH, Di Palma F, Alföldi J, Lindblad-Toh K, Postlethwait JH.

Nat Genet. 2016 Apr;48(4):427-37. doi: 10.1038/ng.3526. Epub 2016 Mar 7.


Three-Dimensional Printing for Planning Occlusion Procedure for a Double-Lobed Left Atrial Appendage.

Fan Y, Kwok KW, Zhang Y, Cheung GS, Chan AK, Lee AP.

Circ Cardiovasc Interv. 2016 Mar;9(3):e003561. doi: 10.1161/CIRCINTERVENTIONS.116.003561. No abstract available.


An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms.

Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP.

Lab Chip. 2016 Mar 7;16(5):868-876. doi: 10.1039/c5lc01563d.


Evaluation of quantum dot immunofluorescence and a digital CMOS imaging system as an alternative to conventional organic fluorescence dyes and laser scanning for quantifying protein microarrays.

Jain A, Taghavian O, Vallejo D, Dotsey E, Schwartz D, Bell FG, Greef C, Davies DH, Grudzien J, Lee AP, Felgner PL, Liang L.

Proteomics. 2016 Apr;16(8):1271-9. doi: 10.1002/pmic.201500375. Epub 2016 Mar 29.


Post-Formation Shrinkage and Stabilization of Microfluidic Bubbles in Lipid Solution.

Shih R, Lee AP.

Langmuir. 2016 Mar 1;32(8):1939-46. doi: 10.1021/acs.langmuir.5b03948. Epub 2016 Feb 18.


The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans.

Coffill CR, Lee AP, Siau JW, Chee SM, Joseph TL, Tan YS, Madhumalar A, Tay BH, Brenner S, Verma CS, Ghadessy FJ, Venkatesh B, Lane DP.

Genes Dev. 2016 Feb 1;30(3):281-92. doi: 10.1101/gad.274118.115. Epub 2016 Jan 21.


Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.

Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP.

Lab Chip. 2016 Jan 21;16(2):282-90. doi: 10.1039/c5lc01050k.


Apical Hypertrophic Cardiomyopathy.

Ho AM, Chui PT, Lee AP, Wan S.

Anesth Analg. 2015 Nov;121(5):1398-9. doi: 10.1213/ANE.0000000000000867. No abstract available.


Importance of chronotropic response and left ventricular long-axis function for exercise performance in patients with heart failure and preserved ejection fraction.

Wang J, Fang F, Yip GW, Sanderson JE, Feng W, Xie JM, Luo XX, Lee AP, Lam YY.

Int J Cardiol. 2016 Jan 1;202:339-43. doi: 10.1016/j.ijcard.2015.09.029. Epub 2015 Sep 25.


The choice of mitral annuloplastic ring-beyond "surgeon's preference".

Wan S, Lee AP, Jin CN, Wong RH, Chan HH, Ng CS, Wan IY, Underwood MJ.

Ann Cardiothorac Surg. 2015 May;4(3):261-5. doi: 10.3978/j.issn.2225-319X.2015.01.05. No abstract available.


Automated quantification of mitral valve anatomy using anatomical intelligence in three-dimensional echocardiography.

Jin CN, Salgo IS, Schneider RJ, Feng W, Meng FX, Kam KK, Chi WK, So CY, Chan C, Sun JP, Tsui G, Wong KY, Yu CM, Wan S, Wong R, Underwood M, Au S, Ng SK, Lee AP.

Int J Cardiol. 2015 Nov 15;199:232-8. doi: 10.1016/j.ijcard.2015.07.018. Epub 2015 Jul 11.


Testicular fine-needle aspiration for the assessment of intratesticular hormone concentrations.

Lee AP, Roth MY, Nya-Ngatchou JJ, Lin K, Walsh TJ, Page ST, Matsumoto AM, Bremner WJ, Amory JK, Anawalt BD.

Asian J Androl. 2016 Jan-Feb;18(1):21-4. doi: 10.4103/1008-682X.156637.


Introducing Final-Year Medical Students to Pocket-Sized Ultrasound Imaging: Teaching Transthoracic Echocardiography on a 2-Week Anesthesia Rotation.

Ho AM, Critchley LA, Leung JY, Kan PK, Au SS, Ng SK, Chan SK, Lam PK, Choi GY, Wai JK, Lee AP, Chan SO.

Teach Learn Med. 2015;27(3):307-13. doi: 10.1080/10401334.2015.1044657.


Abnormal mitral-aortic intervalvular coupling in mitral valve diseases: a study using real-time three-dimensional transesophageal echocardiography.

Looi JL, Lee AP, Fang F, Hsiung MC, Sun JP, Yin WH, Wei J, Tsai SK, Wan S, Wong RH, Underwood MJ, Lin QS, Jin CN, Chen L, Yu CM.

Clin Res Cardiol. 2015 Oct;104(10):831-42. doi: 10.1007/s00392-015-0851-2. Epub 2015 Apr 9.


Evaluation of left ventricular function by three-dimensional speckle-tracking echocardiography in patients with myocardial bridging of the left anterior descending coronary artery.

Wang D, Sun JP, Lee AP, Ma GS, Yang XS, Yu CM, Ding JD, Liu NF.

J Am Soc Echocardiogr. 2015 Jun;28(6):674-82. doi: 10.1016/j.echo.2015.02.012. Epub 2015 Mar 18.


Ancient Duplications and Expression Divergence in the Globin Gene Superfamily of Vertebrates: Insights from the Elephant Shark Genome and Transcriptome.

Opazo JC, Lee AP, Hoffmann FG, Toloza-Villalobos J, Burmester T, Venkatesh B, Storz JF.

Mol Biol Evol. 2015 Jul;32(7):1684-94. doi: 10.1093/molbev/msv054. Epub 2015 Mar 4.


Leaf energy balance modelling as a tool to infer habitat preference in the early angiosperms.

Lee AP, Upchurch G Jr, Murchie EH, Lomax BH.

Proc Biol Sci. 2015 Mar 22;282(1803):20143052. doi: 10.1098/rspb.2014.3052.


Left atrial function as assessed by speckle-tracking echocardiography in hypertension.

Xu TY, Sun JP, Lee AP, Yang XS, Ji L, Zhang Z, Li Y, Yu CM, Wang JG.

Medicine (Baltimore). 2015 Feb;94(6):e526. doi: 10.1097/MD.0000000000000526.

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