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Items: 1 to 50 of 356

1.

The RNA code: nature's Rosetta Stone.

Caskey CT, Leder P.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5758-9. doi: 10.1073/pnas.1404819111. No abstract available.

2.

Retrospective. Marshall Warren Nirenberg (1927-2010).

Leder P.

Science. 2010 Feb 19;327(5968):972. doi: 10.1126/science.1187484. No abstract available.

PMID:
20167780
3.

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

Ravi D, Wiles AM, Bhavani S, Ruan J, Leder P, Bishop AJ.

PLoS Genet. 2009 Jun;5(6):e1000527. doi: 10.1371/journal.pgen.1000527. Epub 2009 Jun 19. Erratum in: PLoS Genet. 2009 Oct;5(10). doi: 10.1371/annotation/526db6e9-0ba5-4ec6-a257-2befb76f34b7.

4.

Formin1 disruption confers oligodactylism and alters Bmp signaling.

Zhou F, Leder P, Zuniga A, Dettenhofer M.

Hum Mol Genet. 2009 Jul 1;18(13):2472-82. doi: 10.1093/hmg/ddp185. Epub 2009 Apr 20.

5.

Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.

Babbe H, McMenamin J, Hobeika E, Wang J, Rodig SJ, Reth M, Leder P.

J Immunol. 2009 Jan 1;182(1):347-60.

6.

An interview with... Philip Leder. Interview by Errol C. Friedberg.

Leder P.

Nat Rev Mol Cell Biol. 2008 Nov;9(11):830. doi: 10.1038/nrm2536. No abstract available.

PMID:
18956482
7.

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.

Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P, Ferguson-Smith AC.

Dev Cell. 2008 Oct;15(4):547-57. doi: 10.1016/j.devcel.2008.08.014.

8.

Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation.

Dettenhofer M, Zhou F, Leder P.

PLoS One. 2008 Jun 18;3(6):e2497. doi: 10.1371/journal.pone.0002497.

9.

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency.

Leder A, McMenamin J, Zhou F, Moran JL, Beier DR, Leder P.

Oncogene. 2008 Apr 10;27(17):2456-65. Epub 2007 Oct 22.

PMID:
17952114
10.
11.

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.

Lu J, Ruhf ML, Perrimon N, Leder P.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9381-6. Epub 2007 May 17.

12.

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.

Babbe H, Chester N, Leder P, Reizis B.

Mol Cell Biol. 2007 Mar;27(5):1947-59. Epub 2007 Jan 8.

13.

Mutation of the murine Bloom's syndrome gene produces global genome destabilization.

Chester N, Babbe H, Pinkas J, Manning C, Leder P.

Mol Cell Biol. 2006 Sep;26(17):6713-26.

14.

Mitochondriotoxic compounds for cancer therapy.

Fantin VR, Leder P.

Oncogene. 2006 Aug 7;25(34):4787-97. Review.

PMID:
16892091
15.

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance.

Fantin VR, St-Pierre J, Leder P.

Cancer Cell. 2006 Jun;9(6):425-34. Erratum in: Cancer Cell. 2006 Aug;10(2):172.

16.

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.

Zhou F, Leder P, Martin SS.

Exp Cell Res. 2006 Apr 15;312(7):1119-26. Epub 2006 Feb 9.

PMID:
16480715
17.

P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.

Ridgeway AG, McMenamin J, Leder P.

Oncogene. 2006 Jun 15;25(25):3518-27. Epub 2006 Jan 23.

PMID:
16434961
18.

A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells.

Fantin VR, Berardi MJ, Babbe H, Michelman MV, Manning CM, Leder P.

Cancer Res. 2005 Aug 1;65(15):6891-900.

19.

The formins: connecting embryonic pattern formation and hypofertility in the mouse.

Leder P.

Ann N Y Acad Sci. 2004 Dec;1038:75-9. No abstract available.

PMID:
15838099
20.

zeta-/- Thalassemic mice are affected by two modifying loci and display unanticipated somatic recombination leading to inherited variation.

Leder A, McMenamin J, Fontaine K, Bishop A, Leder P.

Hum Mol Genet. 2005 Mar 1;14(5):615-25. Epub 2005 Jan 13.

PMID:
15649944
21.

Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD mammary epithelial cells.

Pinkas J, Martin SS, Leder P.

Mol Cancer Res. 2004 Oct;2(10):551-6.

22.

Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin.

Shigematsu H, Reizis B, Iwasaki H, Mizuno S, Hu D, Traver D, Leder P, Sakaguchi N, Akashi K.

Immunity. 2004 Jul;21(1):43-53.

23.

A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.

Martin SS, Ridgeway AG, Pinkas J, Lu Y, Reginato MJ, Koh EY, Michelman M, Daley GQ, Brugge JS, Leder P.

Oncogene. 2004 Jun 3;23(26):4641-5.

PMID:
15064711
25.

Chromosome instability and tumor predisposition inversely correlate with BLM protein levels.

McDaniel LD, Chester N, Watson M, Borowsky AD, Leder P, Schultz RA.

DNA Repair (Amst). 2003 Dec 9;2(12):1387-404.

PMID:
14642567
26.

A conserved role for the Hus1 checkpoint protein in eukaryotic genome maintenance.

Weiss RS, Leder P, Enoch T.

Cold Spring Harb Symp Quant Biol. 2000;65:457-66. Review. No abstract available.

PMID:
12760062
27.
28.

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.

Weiss RS, Leder P, Vaziri C.

Mol Cell Biol. 2003 Feb;23(3):791-803.

29.

RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX.

Michaelson JS, Leder P.

J Cell Sci. 2003 Jan 15;116(Pt 2):345-52.

30.

Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes.

Leader B, Lim H, Carabatsos MJ, Harrington A, Ecsedy J, Pellman D, Maas R, Leder P.

Nat Cell Biol. 2002 Dec;4(12):921-8.

PMID:
12447394
31.
33.

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.

Fantin VR, Berardi MJ, Scorrano L, Korsmeyer SJ, Leder P.

Cancer Cell. 2002 Jul;2(1):29-42.

34.

Tracing lymphopoiesis with the aid of a pTalpha-controlled reporter gene.

Gounari F, Aifantis I, Martin C, Fehling HJ, Hoeflinger S, Leder P, von Boehmer H, Reizis B.

Nat Immunol. 2002 May;3(5):489-96. Epub 2002 Apr 1.

PMID:
11927910
35.
36.

Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway.

Weiss RS, Matsuoka S, Elledge SJ, Leder P.

Curr Biol. 2002 Jan 8;12(1):73-7.

40.
41.

DelBank: a mouse ES-cell resource for generating deletions.

Goodwin NC, Ishida Y, Hartford S, Wnek C, Bergstrom RA, Leder P, Schimenti JC.

Nat Genet. 2001 Aug;28(4):310-1. No abstract available.

PMID:
11479588
43.

Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis.

Brodie SG, Xu X, Li C, Kuo A, Leder P, Deng CX.

Oncogene. 2001 Mar 22;20(12):1445-54.

44.
45.

Ras pathway signals are required for notch-mediated oncogenesis.

Fitzgerald K, Harrington A, Leder P.

Oncogene. 2000 Aug 31;19(37):4191-8.

46.

Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice.

Lane TF, Lin C, Brown MA, Solomon E, Leder P.

Oncogene. 2000 Aug 24;19(36):4085-90.

48.
49.

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