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Items: 32

1.

Microbial ecology perturbation in human IgA deficiency.

Fadlallah J, El Kafsi H, Sterlin D, Juste C, Parizot C, Dorgham K, Autaa G, Gouas D, Almeida M, Lepage P, Pons N, Le Chatelier E, Levenez F, Kennedy S, Galleron N, de Barros JP, Malphettes M, Galicier L, Boutboul D, Mathian A, Miyara M, Oksenhendler E, Amoura Z, Doré J, Fieschi C, Ehrlich SD, Larsen M, Gorochov G.

Sci Transl Med. 2018 May 2;10(439). pii: eaan1217. doi: 10.1126/scitranslmed.aan1217.

PMID:
29720448
2.

Protection of the Human Gut Microbiome From Antibiotics.

de Gunzburg J, Ghozlane A, Ducher A, Le Chatelier E, Duval X, Ruppé E, Armand-Lefevre L, Sablier-Gallis F, Burdet C, Alavoine L, Chachaty E, Augustin V, Varastet M, Levenez F, Kennedy S, Pons N, Mentré F, Andremont A.

J Infect Dis. 2018 Jan 30;217(4):628-636. doi: 10.1093/infdis/jix604.

3.

Correction to 'Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity'.

Paschalis V, Le Chatelier E, Green M, Képès F, Soultanas P, Janniere L.

Open Biol. 2017 Nov;7(11). pii: 170234. doi: 10.1098/rsob.170234. No abstract available.

4.

Correction to: Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis.

Wen C, Zheng Z, Shao T, Liu L, Xie Z, Le Chatelier E, He Z, Zhong W, Fan Y, Zhang L, Li H, Wu C, Hu C, Xu Q, Zhou J, Cai S, Wang D, Huang Y, Breban M, Qin N, Ehrlich SD.

Genome Biol. 2017 Nov 8;18(1):214. doi: 10.1186/s13059-017-1352-6.

5.

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors.

Routy B, Le Chatelier E, Derosa L, Duong CPM, Alou MT, Daillère R, Fluckiger A, Messaoudene M, Rauber C, Roberti MP, Fidelle M, Flament C, Poirier-Colame V, Opolon P, Klein C, Iribarren K, Mondragón L, Jacquelot N, Qu B, Ferrere G, Clémenson C, Mezquita L, Masip JR, Naltet C, Brosseau S, Kaderbhai C, Richard C, Rizvi H, Levenez F, Galleron N, Quinquis B, Pons N, Ryffel B, Minard-Colin V, Gonin P, Soria JC, Deutsch E, Loriot Y, Ghiringhelli F, Zalcman G, Goldwasser F, Escudier B, Hellmann MD, Eggermont A, Raoult D, Albiges L, Kroemer G, Zitvogel L.

Science. 2018 Jan 5;359(6371):91-97. doi: 10.1126/science.aan3706. Epub 2017 Nov 2.

PMID:
29097494
6.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science. 2018 Jan 5;359(6371):97-103. doi: 10.1126/science.aan4236. Epub 2017 Nov 2.

7.

Towards standards for human fecal sample processing in metagenomic studies.

Costea PI, Zeller G, Sunagawa S, Pelletier E, Alberti A, Levenez F, Tramontano M, Driessen M, Hercog R, Jung FE, Kultima JR, Hayward MR, Coelho LP, Allen-Vercoe E, Bertrand L, Blaut M, Brown JRM, Carton T, Cools-Portier S, Daigneault M, Derrien M, Druesne A, de Vos WM, Finlay BB, Flint HJ, Guarner F, Hattori M, Heilig H, Luna RA, van Hylckama Vlieg J, Junick J, Klymiuk I, Langella P, Le Chatelier E, Mai V, Manichanh C, Martin JC, Mery C, Morita H, O'Toole PW, Orvain C, Patil KR, Penders J, Persson S, Pons N, Popova M, Salonen A, Saulnier D, Scott KP, Singh B, Slezak K, Veiga P, Versalovic J, Zhao L, Zoetendal EG, Ehrlich SD, Dore J, Bork P.

Nat Biotechnol. 2017 Nov;35(11):1069-1076. doi: 10.1038/nbt.3960. Epub 2017 Oct 2.

PMID:
28967887
8.

Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity.

Paschalis V, Le Chatelier E, Green M, Képès F, Soultanas P, Janniere L.

Open Biol. 2017 Sep;7(9). pii: 170146. doi: 10.1098/rsob.170146. Erratum in: Open Biol. 2017 Nov;7(11):.

9.

Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis.

Wen C, Zheng Z, Shao T, Liu L, Xie Z, Le Chatelier E, He Z, Zhong W, Fan Y, Zhang L, Li H, Wu C, Hu C, Xu Q, Zhou J, Cai S, Wang D, Huang Y, Breban M, Qin N, Ehrlich SD.

Genome Biol. 2017 Jul 27;18(1):142. doi: 10.1186/s13059-017-1271-6.

10.

Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Pedersen HK, Arumugam M, Kristiansen K, Voigt AY, Vestergaard H, Hercog R, Costea PI, Kultima JR, Li J, Jørgensen T, Levenez F, Dore J; MetaHIT consortium, Nielsen HB, Brunak S, Raes J, Hansen T, Wang J, Ehrlich SD, Bork P, Pedersen O.

Nature. 2017 May 3;545(7652):116. doi: 10.1038/nature22318. No abstract available.

PMID:
28470190
11.

A fibrolytic potential in the human ileum mucosal microbiota revealed by functional metagenomic.

Patrascu O, Béguet-Crespel F, Marinelli L, Le Chatelier E, Abraham AL, Leclerc M, Klopp C, Terrapon N, Henrissat B, Blottière HM, Doré J, Béra-Maillet C.

Sci Rep. 2017 Jan 16;7:40248. doi: 10.1038/srep40248.

12.

A reference gene catalogue of the pig gut microbiome.

Xiao L, Estellé J, Kiilerich P, Ramayo-Caldas Y, Xia Z, Feng Q, Liang S, Pedersen AØ, Kjeldsen NJ, Liu C, Maguin E, Doré J, Pons N, Le Chatelier E, Prifti E, Li J, Jia H, Liu X, Xu X, Ehrlich SD, Madsen L, Kristiansen K, Rogel-Gaillard C, Wang J.

Nat Microbiol. 2016 Sep 19:16161. doi: 10.1038/nmicrobiol.2016.161. [Epub ahead of print]

PMID:
27643971
13.

Human gut microbes impact host serum metabolome and insulin sensitivity.

Pedersen HK, Gudmundsdottir V, Nielsen HB, Hyotylainen T, Nielsen T, Jensen BA, Forslund K, Hildebrand F, Prifti E, Falony G, Le Chatelier E, Levenez F, Doré J, Mattila I, Plichta DR, Pöhö P, Hellgren LI, Arumugam M, Sunagawa S, Vieira-Silva S, Jørgensen T, Holm JB, Trošt K; MetaHIT Consortium, Kristiansen K, Brix S, Raes J, Wang J, Hansen T, Bork P, Brunak S, Oresic M, Ehrlich SD, Pedersen O.

Nature. 2016 Jul 21;535(7612):376-81. Epub 2016 Jul 13.

PMID:
27409811
14.

Dissemination of the mcr-1 colistin resistance gene.

Ruppé E, Le Chatelier E, Pons N, Andremont A, Ehrlich SD.

Lancet Infect Dis. 2016 Mar;16(3):290-1. doi: 10.1016/S1473-3099(16)00066-9. No abstract available.

PMID:
26973305
15.

Capturing the most wanted taxa through cross-sample correlations.

Almeida M, Pop M, Le Chatelier E, Prifti E, Pons N, Ghozlane A, Ehrlich SD.

ISME J. 2016 Oct;10(10):2459-67. doi: 10.1038/ismej.2016.35. Epub 2016 Mar 4.

16.

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Pedersen HK, Arumugam M, Kristiansen K, Voigt AY, Vestergaard H, Hercog R, Costea PI, Kultima JR, Li J, Jørgensen T, Levenez F, Dore J; MetaHIT consortium, Nielsen HB, Brunak S, Raes J, Hansen T, Wang J, Ehrlich SD, Bork P, Pedersen O.

Nature. 2015 Dec 10;528(7581):262-266. doi: 10.1038/nature15766. Epub 2015 Dec 2. Erratum in: Nature. 2017 May 3;545(7652):116.

17.

A catalog of the mouse gut metagenome.

Xiao L, Feng Q, Liang S, Sonne SB, Xia Z, Qiu X, Li X, Long H, Zhang J, Zhang D, Liu C, Fang Z, Chou J, Glanville J, Hao Q, Kotowska D, Colding C, Licht TR, Wu D, Yu J, Sung JJ, Liang Q, Li J, Jia H, Lan Z, Tremaroli V, Dworzynski P, Nielsen HB, Bäckhed F, Doré J, Le Chatelier E, Ehrlich SD, Lin JC, Arumugam M, Wang J, Madsen L, Kristiansen K.

Nat Biotechnol. 2015 Oct;33(10):1103-8. doi: 10.1038/nbt.3353. Epub 2015 Sep 28.

PMID:
26414350
18.

Qin et al. reply.

Qin N, Le Chatelier E, Guo J, Prifti E, Li L, Ehrlich SD.

Nature. 2015 Sep 17;525(7569):E2-3. doi: 10.1038/nature14852. No abstract available.

PMID:
26381989
19.

Dietary modulation of the gut microbiota--a randomised controlled trial in obese postmenopausal women.

Brahe LK, Le Chatelier E, Prifti E, Pons N, Kennedy S, Blædel T, Håkansson J, Dalsgaard TK, Hansen T, Pedersen O, Astrup A, Ehrlich SD, Larsen LH.

Br J Nutr. 2015 Aug 14;114(3):406-17. doi: 10.1017/S0007114515001786. Epub 2015 Jul 2.

20.

Specific gut microbiota features and metabolic markers in postmenopausal women with obesity.

Brahe LK, Le Chatelier E, Prifti E, Pons N, Kennedy S, Hansen T, Pedersen O, Astrup A, Ehrlich SD, Larsen LH.

Nutr Diabetes. 2015 Jun 15;5:e159. doi: 10.1038/nutd.2015.9.

21.

Alterations of the human gut microbiome in liver cirrhosis.

Qin N, Yang F, Li A, Prifti E, Chen Y, Shao L, Guo J, Le Chatelier E, Yao J, Wu L, Zhou J, Ni S, Liu L, Pons N, Batto JM, Kennedy SP, Leonard P, Yuan C, Ding W, Chen Y, Hu X, Zheng B, Qian G, Xu W, Ehrlich SD, Zheng S, Li L.

Nature. 2014 Sep 4;513(7516):59-64. doi: 10.1038/nature13568. Epub 2014 Jul 23.

PMID:
25079328
22.

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.

Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sunagawa S, Plichta DR, Gautier L, Pedersen AG, Le Chatelier E, Pelletier E, Bonde I, Nielsen T, Manichanh C, Arumugam M, Batto JM, Quintanilha Dos Santos MB, Blom N, Borruel N, Burgdorf KS, Boumezbeur F, Casellas F, Doré J, Dworzynski P, Guarner F, Hansen T, Hildebrand F, Kaas RS, Kennedy S, Kristiansen K, Kultima JR, Léonard P, Levenez F, Lund O, Moumen B, Le Paslier D, Pons N, Pedersen O, Prifti E, Qin J, Raes J, Sørensen S, Tap J, Tims S, Ussery DW, Yamada T; MetaHIT Consortium, Renault P, Sicheritz-Ponten T, Bork P, Wang J, Brunak S, Ehrlich SD; MetaHIT Consortium.

Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6.

PMID:
24997787
23.

Dietary intervention impact on gut microbial gene richness.

Cotillard A, Kennedy SP, Kong LC, Prifti E, Pons N, Le Chatelier E, Almeida M, Quinquis B, Levenez F, Galleron N, Gougis S, Rizkalla S, Batto JM, Renault P; ANR MicroObes consortium, Doré J, Zucker JD, Clément K, Ehrlich SD.

Nature. 2013 Aug 29;500(7464):585-8. doi: 10.1038/nature12480. Erratum in: Nature. 2013 Oct 24;502(7472)580.

PMID:
23985875
24.

Richness of human gut microbiome correlates with metabolic markers.

Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, Almeida M, Arumugam M, Batto JM, Kennedy S, Leonard P, Li J, Burgdorf K, Grarup N, Jørgensen T, Brandslund I, Nielsen HB, Juncker AS, Bertalan M, Levenez F, Pons N, Rasmussen S, Sunagawa S, Tap J, Tims S, Zoetendal EG, Brunak S, Clément K, Doré J, Kleerebezem M, Kristiansen K, Renault P, Sicheritz-Ponten T, de Vos WM, Zucker JD, Raes J, Hansen T; MetaHIT consortium, Bork P, Wang J, Ehrlich SD, Pedersen O.

Nature. 2013 Aug 29;500(7464):541-6. doi: 10.1038/nature12506.

PMID:
23985870
25.

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis.

Rannou O, Le Chatelier E, Larson MA, Nouri H, Dalmais B, Laughton C, Jannière L, Soultanas P.

Nucleic Acids Res. 2013 May 1;41(10):5303-20. doi: 10.1093/nar/gkt207. Epub 2013 Apr 5.

26.

Genetic evidence for a link between glycolysis and DNA replication.

Jannière L, Canceill D, Suski C, Kanga S, Dalmais B, Lestini R, Monnier AF, Chapuis J, Bolotin A, Titok M, Le Chatelier E, Ehrlich SD.

PLoS One. 2007 May 16;2(5):e447.

27.

Involvement of DnaE, the second replicative DNA polymerase from Bacillus subtilis, in DNA mutagenesis.

Le Chatelier E, Bécherel OJ, d'Alençon E, Canceill D, Ehrlich SD, Fuchs RP, Jannière L.

J Biol Chem. 2004 Jan 16;279(3):1757-67. Epub 2003 Oct 30.

28.
29.

Countertranscript-driven attenuation system of the pAM beta 1 repE gene.

Le Chatelier E, Ehrlich SD, Jannière L.

Mol Microbiol. 1996 Jun;20(5):1099-112.

PMID:
8809762
30.

The pAM beta 1 CopF repressor regulates plasmid copy number by controlling transcription of the repE gene.

Le Chatelier E, Ehrlich SD, Jannière L.

Mol Microbiol. 1994 Nov;14(3):463-71.

PMID:
7885230
31.

A fourth class of theta-replicating plasmids: the pAM beta 1 family from gram-positive bacteria.

Bruand C, Le Chatelier E, Ehrlich SD, Jannière L.

Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11668-72.

32.

Biochemical and genetic analysis of the unidirectional theta replication of the S. agalactiae plasmid pIP501.

Le Chatelier E, Ehrlich SD, Jannière L.

Plasmid. 1993 Jan;29(1):50-6.

PMID:
8441768

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