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Items: 40

1.

Liarozole fumarate inhibits the metabolism of 4-keto-all-trans-retinoic acid.

Van Wauwe J, Coene MC, Cools W, Goossens J, Lauwers W, Le Jeune L, Van Hove C, Van Nyen G.

Biochem Pharmacol. 1994 Feb 11;47(4):737-41.

PMID:
8129749
2.

The metabolism and excretion of risperidone after oral administration in rats and dogs.

Meuldermans W, Hendrickx J, Mannens G, Lavrijsen K, Janssen C, Bracke J, Le Jeune L, Lauwers W, Heykants J.

Drug Metab Dispos. 1994 Jan-Feb;22(1):129-38.

PMID:
7512019
3.

Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes.

Lavrijsen K, van Houdt J, van Dyck D, Hendrickx J, Bockx M, Hurkmans R, Meuldermans W, Le Jeune L, Lauwers W, Heykants J.

Xenobiotica. 1992 Jul;22(7):815-36.

PMID:
1455902
4.

Norharman, a normal body constituent.

Fekkes D, Schouten MJ, Pepplinkhuizen L, Bruinvels J, Lauwers W, Brinkman UA.

Lancet. 1992 Feb 22;339(8791):506. No abstract available.

PMID:
1346874
5.

Suggested mechanism for the formation of 15-hydroxyeicosatrienoic acid by rat epidermal microsomes.

Van Wauwe J, Coene MC, Van Nyen G, Cools W, Le Jeune L, Lauwers W.

Eicosanoids. 1992;5(3-4):141-6.

PMID:
1292524
6.

NADPH-dependent formation of 15- and 12-hydroxyeicosatrienoic acid from arachidonic acid by rat epidermal microsomes.

Van Wauwe J, Coene MC, Van Nyen G, Cools W, Goossens J, Le Jeune L, Lauwers W, Janssen PA.

Eicosanoids. 1991;4(3):155-63.

PMID:
1772688
7.

R 76713 and enantiomers: selective, nonsteroidal inhibitors of the cytochrome P450-dependent oestrogen synthesis.

Vanden Bossche H, Willemsens G, Roels I, Bellens D, Moereels H, Coene MC, Le Jeune L, Lauwers W, Janssen PA.

Biochem Pharmacol. 1990 Oct 15;40(8):1707-18.

PMID:
2242008
8.

Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.

Lavrijsen K, Van Houdt J, Van Dyck D, Hendrickx J, Lauwers W, Hurkmans R, Bockx M, Janssen C, Meuldermans W, Heykants J.

Drug Metab Dispos. 1990 Sep-Oct;18(5):704-10.

PMID:
1981724
9.

On the use of laser microprobe mass spectrometry for the analysis of organic biomolecules.

Van Vaeck L, Van Espen P, Adams F, Gijbels R, Lauwers W, Esmans E.

Biomed Environ Mass Spectrom. 1989 Aug;18(8):581-91.

PMID:
2529934
10.

Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages.

Hart DT, Lauwers WJ, Willemsens G, Vanden Bossche H, Opperdoes FR.

Mol Biochem Parasitol. 1989 Mar 1;33(2):123-34.

PMID:
2542790
11.

Structural characterization of drugs and oxygenated metabolites by laser microprobe mass spectrometry (LAMMA).

Van Vaeck L, Van Espen P, Gijbels R, Lauwers W.

Biomed Environ Mass Spectrom. 1988 Oct;16(1-12):121-9.

PMID:
3242660
12.

Is the metabolism of alfentanil subject to debrisoquine polymorphism? A study using human liver microsomes.

Lavrijsen KL, Van Houdt JM, Van Dyck DM, Hendrickx JJ, Woestenborghs RJ, Lauwers W, Meuldermans WE, Heykants JJ.

Anesthesiology. 1988 Oct;69(4):535-40.

PMID:
3140691
13.

Alfentanil pharmacokinetics and metabolism in humans.

Meuldermans W, Van Peer A, Hendrickx J, Woestenborghs R, Lauwers W, Heykants J, Vanden Bussche G, Van Craeyvelt H, Van der Aa P.

Anesthesiology. 1988 Oct;69(4):527-34.

PMID:
3140690
14.

Absorption, metabolism and excretion of ketanserin in man after oral administration.

Meuldermans W, Hendrickx J, Woestenborghs R, Van Peer A, Lauwers W, De Cree J, Heykants J.

Arzneimittelforschung. 1988 Jun;38(6):789-94.

PMID:
3178919
15.

Ketoconazole inhibits the in vitro and in vivo metabolism of all-trans-retinoic acid.

Van Wauwe JP, Coene MC, Goossens J, Van Nijen G, Cools W, Lauwers W.

J Pharmacol Exp Ther. 1988 May;245(2):718-22.

PMID:
3367313
16.

Excretion and biotransformation of cisapride in rats after oral administration.

Meuldermans W, Hendrickx J, Lauwers W, Hurkmans R, Mostmans E, Swysen E, Bracke J, Knaeps A, Heykants J.

Drug Metab Dispos. 1988 May-Jun;16(3):410-9.

PMID:
2900733
17.

Excretion and biotransformation of cisapride in dogs and humans after oral administration.

Meuldermans W, Van Peer A, Hendrickx J, Lauwers W, Swysen E, Bockx M, Woestenborghs R, Heykants J.

Drug Metab Dispos. 1988 May-Jun;16(3):403-9.

PMID:
2900732
18.

Identification of a biliary metabolite of cisapride.

Lauwers W, Le Jeune L, Meuldermans W.

Biomed Environ Mass Spectrom. 1988 Mar 15;15(6):323-8.

PMID:
3378119
19.

Metabolism of alfentanil by isolated hepatocytes of rat and dog.

Lavrijsen K, Van Houdt J, Meuldermans W, Knaeps F, Hendrickx J, Lauwers W, Hurkmans R, Heykants J.

Xenobiotica. 1988 Feb;18(2):183-97.

PMID:
3131971
20.

Excretion and biotransformation of alfentanil and sufentanil in rats and dogs.

Meuldermans W, Hendrickx J, Lauwers W, Hurkmans R, Swysen E, Thijssen J, Timmerman P, Woestenborghs R, Heykants J.

Drug Metab Dispos. 1987 Nov-Dec;15(6):905-13.

PMID:
2893720
21.

Identification of 17 alpha,20 alpha-dihydroxyprogesterone in testicular extracts after incubation with ketoconazole.

Lauwers WF, Le Jeune L, Vanden Bossche H, Willemsens G.

Biomed Mass Spectrom. 1985 Jun;12(6):296-301.

PMID:
3160407
22.

Ketoconazole an inhibitor of the cytochrome P-450 dependent testosterone biosynthesis.

Vanden Bossche H, Lauwers W, Willemsens G, Cools W.

Prog Clin Biol Res. 1985;185A:187-96. No abstract available.

PMID:
4034576
23.

Excretion and biotransformation of ketanserin after oral and intravenous administration in rats and dogs.

Meuldermans W, Hendrickx J, Lauwers W, Swysen E, Hurkmans R, Knaeps F, Woestenborghs R, Heykants J.

Drug Metab Dispos. 1984 Nov-Dec;12(6):772-81.

PMID:
6150829
24.

Plasma levels, biotransformation and excretion of oxatomide (R 35 443) in rats, dogs and man.

Meuldermans W, Hendrickx J, Knaeps F, Lauwers W, Heykants J, Grindel JM.

Xenobiotica. 1984 Jun;14(6):445-62.

PMID:
6475104
25.

Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles.

Van den Bossche H, Willemsens G, Cools W, Marichal P, Lauwers W.

Biochem Soc Trans. 1983 Dec;11(6):665-7. No abstract available.

PMID:
6667774
26.

Mass spectral investigation of the metabolites of lorcainide in man.

Lauwers WF, Meuldermans WE, Bracke JO.

Eur J Drug Metab Pharmacokinet. 1983 Oct-Dec;8(4):351-62.

PMID:
6673972
27.

Excretion and metabolism of lorcainide in rats, dogs and man.

Meuldermans W, Hurkmans R, Swysen E, Hendrickx J, Thijssen J, Lauwers W, Heykants J.

Eur J Drug Metab Pharmacokinet. 1983 Oct-Dec;8(4):335-49.

PMID:
6673971
28.

Excretion and metabolism of flunarizine in rats and dogs.

Meuldermans W, Hendrickx J, Hurkmans R, Swysen E, Woestenborghs R, Lauwers W, Heykants J.

Arzneimittelforschung. 1983;33(8):1142-51.

PMID:
6685491
29.

On the pharmacokinetics of domperidone in animals and man III. Comparative study on the excretion and metabolism of domperidone in rats, dogs and man.

Meuldermans W, Hurkmans R, Swysen E, Hendrickx J, Michiels M, Lauwers W, Heykants J.

Eur J Drug Metab Pharmacokinet. 1981;6(1):49-60.

PMID:
6788556
30.

In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.

Van den Bossche H, Willemsens G, Cools W, Cornelissen F, Lauwers WF, van Cutsem JM.

Antimicrob Agents Chemother. 1980 Jun;17(6):922-8.

31.

Structure of the major gangliosides from bovine thyroid.

Van Dessel GA, Lagrou AR, Hilderson HJ, Dierick WS, Lauwers WF.

J Biol Chem. 1979 Sep 25;254(18):9305-10.

32.

Mass spectrometric analysis of permethylated gangliosides of bovine thyroid [proceedings].

Van Dessel G, Lagrou A, Hilderson HJ, Dierick W, Lauwers W.

Arch Int Physiol Biochim. 1979 Feb;87(1):215-6. No abstract available.

PMID:
92283
33.

Domperidone for the symptomatic treatment of chronic post-prandial nausea and vomiting.

Van Outryve M, Lauwers W, Verbeke S.

Postgrad Med J. 1979;55 Suppl 1:33-5.

PMID:
382152
34.

Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans.

van den Bossche H, Willemsens G, Cools W, Lauwers WF, Le Jeune L.

Chem Biol Interact. 1978 Apr;21(1):59-78. No abstract available.

PMID:
352553
35.

In vitro metabolism of lidoflazine by rat and dog liver fractions.

Meuldermans W, Lauwers W, Knaeps A, Heykants J.

Arzneimittelforschung. 1977;27(4):828-32.

PMID:
577461
36.

Miconazole alcoholic solution in the treatment of mycotic nail infections.

Vanderdonckt J, Lauwers W, Bockaert J.

Mykosen. 1976 Jul;19(7):251-6. No abstract available.

PMID:
135927
37.

In-vitro metabolism of etomidate by rat liver fractions.

Meuldermans WE, Lauwers WF, Heykants JJ.

Arch Int Pharmacodyn Ther. 1976 May;221(1):140-9.

PMID:
962424
38.

[Colonic and rectal leiomyoma].

Lauwers W, Bockaert J, Ponette E, Geboes K, Van Trappen G.

Tijdschr Gastroenterol. 1976;19(4):247-52. Dutch. No abstract available.

PMID:
1013992
39.
40.

Plasma testosterone, estradiol, and gonadotrophins in hepatic insufficiency.

Kent JR, Scaramuzzi RJ, Lauwers W, Parlow AF, Hill M, Penardi R, Hilliard J.

Gastroenterology. 1973 Jan;64(1):111-5. No abstract available.

PMID:
4734260

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