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Items: 1 to 50 of 445

1.

Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration.

Quansah E, Peelaerts W, Langston JW, Simon DK, Colca J, Brundin P.

Mol Neurodegener. 2018 May 24;13(1):28. doi: 10.1186/s13024-018-0260-x. Review.

2.

Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Kluge AF, Patane MA, Van Drie JH, Wang C, McElligott D, Kesicki EA, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2018 May 16. doi: 10.1038/s41586-018-0111-5. [Epub ahead of print]

PMID:
29769713
3.

MPTP-induced parkinsonism: an historical case series.

Nonnekes J, Post B, Tetrud JW, Langston JW, Bloem BR.

Lancet Neurol. 2018 Apr;17(4):300-301. doi: 10.1016/S1474-4422(18)30072-3. Epub 2018 Mar 13. No abstract available. Erratum in: Lancet Neurol. 2018 Mar 27;:.

PMID:
29553378
4.

Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm.

Langston JW, Wiley JC, Tagliati M.

NPJ Parkinsons Dis. 2018 Feb 23;4:5. doi: 10.1038/s41531-018-0041-9. eCollection 2018. Review.

5.

LRRK2 p.Ile1371Val Mutation in a Case with Neuropathologically Confirmed Multi-System Atrophy.

Lee K, Nguyen KD, Sun C, Liu M, Zafar F, Saetern J, Flierl A, Tetrud JW, Langston JW, Dickson D, Schüle B.

J Parkinsons Dis. 2018;8(1):93-100. doi: 10.3233/JPD-171237.

PMID:
29480226
6.

Behavioral toxicity of sodium cyanide following oral ingestion in rats: Dose-dependent onset, severity, survival, and recovery.

Rice NC, Rauscher NA, Langston JL, Myers TM.

Food Chem Toxicol. 2018 Apr;114:145-154. doi: 10.1016/j.fct.2018.02.033. Epub 2018 Feb 16.

PMID:
29454866
7.

Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.

Michaelides MR, Kluge A, Patane M, Van Drie JH, Wang C, Hansen TM, Risi RM, Mantei R, Hertel C, Karukurichi K, Nesterov A, McElligott D, de Vries P, Langston JW, Cole PA, Marmorstein R, Liu H, Lasko L, Bromberg KD, Lai A, Kesicki EA.

ACS Med Chem Lett. 2017 Dec 13;9(1):28-33. doi: 10.1021/acsmedchemlett.7b00395. eCollection 2018 Jan 11.

8.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Erratum in: Nature. 2018 May 16;:.

PMID:
28953875
9.

Parkinson's disease associated with pure ATXN10 repeat expansion.

Schüle B, McFarland KN, Lee K, Tsai YC, Nguyen KD, Sun C, Liu M, Byrne C, Gopi R, Huang N, Langston JW, Clark T, Gil FJJ, Ashizawa T.

NPJ Parkinsons Dis. 2017 Sep 5;3:27. doi: 10.1038/s41531-017-0029-x. eCollection 2017.

10.

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.

Obeso JA, Stamelou M, Goetz CG, Poewe W, Lang AE, Weintraub D, Burn D, Halliday GM, Bezard E, Przedborski S, Lehericy S, Brooks DJ, Rothwell JC, Hallett M, DeLong MR, Marras C, Tanner CM, Ross GW, Langston JW, Klein C, Bonifati V, Jankovic J, Lozano AM, Deuschl G, Bergman H, Tolosa E, Rodriguez-Violante M, Fahn S, Postuma RB, Berg D, Marek K, Standaert DG, Surmeier DJ, Olanow CW, Kordower JH, Calabresi P, Schapira AHV, Stoessl AJ.

Mov Disord. 2017 Sep;32(9):1264-1310. doi: 10.1002/mds.27115. Review.

PMID:
28887905
11.

Behavioral intoxication following voluntary oral ingestion of tetramethylenedisulfotetramine: Dose-dependent onset, severity, survival, and recovery.

Rice NC, Rauscher NA, Langston JL, Myers TM.

Neurotoxicology. 2017 Dec;63:21-32. doi: 10.1016/j.neuro.2017.08.009. Epub 2017 Sep 7.

PMID:
28855111
12.

The Expanding Role of Advanced Practice Providers in Urologic Procedural Care.

Langston JP, Duszak R Jr, Orcutt VL, Schultz H, Hornberger B, Jenkins LC, Hemingway J, Hughes DR, Pruthi RS, Nielsen ME.

Urology. 2017 Aug;106:70-75. doi: 10.1016/j.urology.2017.03.047. Epub 2017 Apr 20.

PMID:
28435035
13.

The MPTP Story.

Langston JW.

J Parkinsons Dis. 2017;7(s1):S11-S22. doi: 10.3233/JPD-179006. No abstract available.

14.

VX toxicity in the Göttingen minipig.

Langston JL, Myers TM.

Toxicol Lett. 2016 Dec 15;264:12-19. doi: 10.1016/j.toxlet.2016.10.011. Epub 2016 Oct 20.

PMID:
27773723
15.

Parkinson's disease is ready for precision medicine.

Sherer TB, Frasier MA, Langston JW, Fiske BK.

Per Med. 2016 Sep;13(5):405-407. doi: 10.2217/pme-2016-0052. Epub 2016 Aug 9. No abstract available.

16.

Projecting the Urology Workforce Over the Next 20 Years.

McKibben MJ, Kirby EW, Langston J, Raynor MC, Nielsen ME, Smith AB, Wallen EM, Woods ME, Pruthi RS.

Urology. 2016 Dec;98:21-26. doi: 10.1016/j.urology.2016.07.028. Epub 2016 Aug 1.

PMID:
27491965
17.

Is PARKIN parkinsonism a cancer predisposition syndrome?

Schüle B, Byrne C, Rees L, Langston JW.

Neurol Genet. 2015 Oct 15;1(4):e31. doi: 10.1212/NXG.0000000000000031. eCollection 2015 Dec.

18.

Erratum: Multisystem Lewy body disease and the other parkinsonian disorders.

Langston JW, Schüle B, Rees L, Nichols RJ, Barlow C.

Nat Genet. 2016 Apr;48(4):473. doi: 10.1038/ng0329-473b. No abstract available.

PMID:
27023778
19.

Staged total hip arthroplasty in a patient with hip dysplasia and a large pertrochanteric bone cyst.

Langston JR, DeHaan AM, Huff TW.

Arthroplast Today. 2016 May 24;2(2):57-61. doi: 10.1016/j.artd.2016.03.002. eCollection 2016 Jun.

20.

Multisystem Lewy body disease and the other parkinsonian disorders.

Langston JW, Schüle B, Rees L, Nichols RJ, Barlow C.

Nat Genet. 2015 Dec;47(12):1378-84. doi: 10.1038/ng.3454. Erratum in: Nat Genet. 2016 Apr;48(4):473.

PMID:
26620112
21.

Gender Differences in Compensation, Job Satisfaction and Other Practice Patterns in Urology.

Spencer ES, Deal AM, Pruthi NR, Gonzalez CM, Kirby EW, Langston J, McKenna PH, McKibben MJ, Nielsen ME, Raynor MC, Wallen EM, Woods ME, Pruthi RS, Smith AB.

J Urol. 2016 Feb;195(2):450-5. doi: 10.1016/j.juro.2015.08.100. Epub 2015 Sep 15.

22.

Comparative genomic hybridization solves a 14-year-old PARKIN mystery.

Schüle B, Hatchwell E, Eis PS, Langston JW.

Ann Neurol. 2015 Oct;78(4):663-4. doi: 10.1002/ana.24478. Epub 2015 Aug 29. No abstract available.

PMID:
26179350
23.

When DLB, PD, and PSP masquerade as MSA: an autopsy study of 134 patients.

Koga S, Aoki N, Uitti RJ, van Gerpen JA, Cheshire WP, Josephs KA, Wszolek ZK, Langston JW, Dickson DW.

Neurology. 2015 Aug 4;85(5):404-12. doi: 10.1212/WNL.0000000000001807. Epub 2015 Jul 2.

24.

LRRK2 dephosphorylation increases its ubiquitination.

Zhao J, Molitor TP, Langston JW, Nichols RJ.

Biochem J. 2015 Jul 1;469(1):107-20. doi: 10.1042/BJ20141305. Epub 2015 May 5.

25.

Defining the minimally effective dose and schedule for parenteral hydrogen sulfide: long-term benefits in a rat model of hindlimb ischemia.

Langston JW, Toombs CF.

Med Gas Res. 2015 Apr 16;5:5. doi: 10.1186/s13618-015-0027-1. eCollection 2015.

26.

Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease.

Furlong M, Tanner CM, Goldman SM, Bhudhikanok GS, Blair A, Chade A, Comyns K, Hoppin JA, Kasten M, Korell M, Langston JW, Marras C, Meng C, Richards M, Ross GW, Umbach DM, Sandler DP, Kamel F.

Environ Int. 2015 Feb;75:144-50. doi: 10.1016/j.envint.2014.11.002. Epub 2014 Nov 21.

27.

Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease.

Kalia LV, Lang AE, Hazrati LN, Fujioka S, Wszolek ZK, Dickson DW, Ross OA, Van Deerlin VM, Trojanowski JQ, Hurtig HI, Alcalay RN, Marder KS, Clark LN, Gaig C, Tolosa E, Ruiz-Martínez J, Marti-Masso JF, Ferrer I, López de Munain A, Goldman SM, Schüle B, Langston JW, Aasly JO, Giordana MT, Bonifati V, Puschmann A, Canesi M, Pezzoli G, Maues De Paula A, Hasegawa K, Duyckaerts C, Brice A, Stoessl AJ, Marras C.

JAMA Neurol. 2015 Jan;72(1):100-5. doi: 10.1001/jamaneurol.2014.2704.

28.

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B.

PLoS One. 2014 Nov 12;9(11):e112413. doi: 10.1371/journal.pone.0112413. eCollection 2014.

29.

Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms.

Riley BE, Gardai SJ, Emig-Agius D, Bessarabova M, Ivliev AE, Schüle B, Alexander J, Wallace W, Halliday GM, Langston JW, Braxton S, Yednock T, Shaler T, Johnston JA.

PLoS One. 2014 Aug 29;9(8):e102909. doi: 10.1371/journal.pone.0102909. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e115081. Schüle, Birgit [corrected to Schüle, Birgitt].

30.

Michael J. Fox Foundation LRRK2 Consortium: geographical differences in returning genetic research data to study participants.

Alcalay RN, Aasly J, Berg D, Bressman S, Brice A, Brockmann K, Chan P, Clark L, Cormier F, Corvol JC, Durr A, Facheris M, Farrer M, Foroud TM, Gasser T, Giladi N, Halter C, Lang A, Langston JW, Marras C, Marti-Masso JF, Ruiz Martinez J, Mejia-Santana H, Mirelman A, Pont-Sunyer C, Orr-Urtreger A, Raymond D, Saunders-Pullman R, Schüle B, Tanner C, Tolosa E, Urkowitz A, Vilas D, Wise A, Marder K.

Genet Med. 2014 Aug;16(8):644-5. doi: 10.1038/gim.2014.55. No abstract available.

31.

Peyronie's disease: review and recent advances.

Langston JP, Carson CC 3rd.

Maturitas. 2014 Aug;78(4):341-3. doi: 10.1016/j.maturitas.2014.05.024. Epub 2014 Jun 6. Review.

PMID:
24984940
32.

Peptidoglycan recognition protein genes and risk of Parkinson's disease.

Goldman SM, Kamel F, Ross GW, Jewell SA, Marras C, Hoppin JA, Umbach DM, Bhudhikanok GS, Meng C, Korell M, Comyns K, Hauser RA, Jankovic J, Factor SA, Bressman S, Lyons KE, Sandler DP, Langston JW, Tanner CM.

Mov Disord. 2014 Aug;29(9):1171-80. doi: 10.1002/mds.25895. Epub 2014 May 17.

33.

Deep Venous Thrombosis as a Complication of Reservoir Placement in Post-Prostatectomy Erectile Dysfunction and Urinary Incontinence Prosthetic Surgery.

Selph JP, McKim SE, Langston JP, Carson CC.

Sex Med Rev. 2014 Apr;2(2):59-63. doi: 10.1002/smrj.28. Epub 2015 Oct 19. Review.

PMID:
27784590
34.

Trends in the diagnosis of SLAP lesions in the US military.

Waterman BR, Cameron KL, Hsiao M, Langston JR, Clark NJ, Owens BD.

Knee Surg Sports Traumatol Arthrosc. 2015 May;23(5):1453-9. doi: 10.1007/s00167-013-2798-z. Epub 2013 Dec 10.

PMID:
24318507
35.

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Sanders LH, Laganière J, Cooper O, Mak SK, Vu BJ, Huang YA, Paschon DE, Vangipuram M, Sundararajan R, Urnov FD, Langston JW, Gregory PD, Zhang HS, Greenamyre JT, Isacson O, Schüle B.

Neurobiol Dis. 2014 Feb;62:381-6. doi: 10.1016/j.nbd.2013.10.013. Epub 2013 Oct 19.

36.

Economic impact of training and career decisions on urological surgery.

Langston JP, Kirby EW, Nielsen ME, Smith AB, Woods ME, Wallen EM, Pruthi RS.

J Urol. 2014 Mar;191(3):755-60. doi: 10.1016/j.juro.2013.09.060. Epub 2013 Oct 2.

PMID:
24096119
37.

Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.

Gardai SJ, Mao W, Schüle B, Babcock M, Schoebel S, Lorenzana C, Alexander J, Kim S, Glick H, Hilton K, Fitzgerald JK, Buttini M, Chiou SS, McConlogue L, Anderson JP, Schenk DB, Bard F, Langston JW, Yednock T, Johnston JA.

PLoS One. 2013 Aug 23;8(8):e71634. doi: 10.1371/journal.pone.0071634. eCollection 2013.

38.

Rethinking osteoporosis: balancing risk and benefit in diagnosis, prevention, and treatment.

Smith A, Shaw B, Laliberte D, Langston J, Bushardt RL.

JAAPA. 2013 Aug;26(8):20-7.

PMID:
24049936
39.

Allograft distal biceps reconstruction after closed intramuscular transection with delayed presentation.

Waterman BR, Langston J, Slade DL.

J Shoulder Elbow Surg. 2013 May;22(5):e10-3. doi: 10.1016/j.jse.2013.01.007. Epub 2013 Mar 19. No abstract available.

PMID:
23523305
40.

Relationship of neighboring tissue and gliosis to α-synuclein pathology in a fetal transplant for Parkinson's disease.

Ahn TB, Langston JW, Aachi VR, Dickson DW.

Am J Neurodegener Dis. 2012;1(1):49-59. Epub 2012 Apr 18.

41.

Genetic modification of the association of paraquat and Parkinson's disease.

Goldman SM, Kamel F, Ross GW, Bhudhikanok GS, Hoppin JA, Korell M, Marras C, Meng C, Umbach DM, Kasten M, Chade AR, Comyns K, Richards MB, Sandler DP, Blair A, Langston JW, Tanner CM.

Mov Disord. 2012 Nov;27(13):1652-8. doi: 10.1002/mds.25216. Epub 2012 Oct 8.

42.

Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants.

Wang C, Cai Y, Zheng Z, Tang BS, Xu Y, Wang T, Ma J, Chen SD, Langston JW, Tanner CM, Chan P; Chinese Parkinson Study Group (CPSG).

Parkinsonism Relat Disord. 2012 Sep;18(8):958-63. Epub 2012 Jun 2.

PMID:
22658533
43.

Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage.

Mak SK, Huang YA, Iranmanesh S, Vangipuram M, Sundararajan R, Nguyen L, Langston JW, Schüle B.

Stem Cells Int. 2012;2012:140427. doi: 10.1155/2012/140427. Epub 2012 Apr 10.

44.

α-Synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits.

Hallett PJ, McLean JR, Kartunen A, Langston JW, Isacson O.

Neurobiol Dis. 2012 Aug;47(2):258-67. doi: 10.1016/j.nbd.2012.04.009. Epub 2012 Apr 19.

45.

Cloning, expression, and characterization of a cellobiose dehydrogenase from Thielavia terrestris induced under cellulose growth conditions.

Langston JA, Brown K, Xu F, Borch K, Garner A, Sweeney MD.

Biochim Biophys Acta. 2012 Jun;1824(6):802-12. doi: 10.1016/j.bbapap.2012.03.009. Epub 2012 Mar 30.

PMID:
22484439
46.

Head injury, α-synuclein Rep1, and Parkinson's disease.

Goldman SM, Kamel F, Ross GW, Jewell SA, Bhudhikanok GS, Umbach D, Marras C, Hauser RA, Jankovic J, Factor SA, Bressman S, Lyons KE, Meng C, Korell M, Roucoux DF, Hoppin JA, Sandler DP, Langston JW, Tanner CM.

Ann Neurol. 2012 Jan;71(1):40-8. doi: 10.1002/ana.22499.

47.

Journal of Parkinson's Disease--an excellent first year and a new sister.

Brundin P, Langston JW.

J Parkinsons Dis. 2012;2(2):77. doi: 10.3233/JPD-2012-12901. No abstract available.

PMID:
23933746
48.

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress.

Byers B, Cord B, Nguyen HN, Schüle B, Fenno L, Lee PC, Deisseroth K, Langston JW, Pera RR, Palmer TD.

PLoS One. 2011;6(11):e26159. doi: 10.1371/journal.pone.0026159. Epub 2011 Nov 16.

49.

Solvent exposures and Parkinson disease risk in twins.

Goldman SM, Quinlan PJ, Ross GW, Marras C, Meng C, Bhudhikanok GS, Comyns K, Korell M, Chade AR, Kasten M, Priestley B, Chou KL, Fernandez HH, Cambi F, Langston JW, Tanner CM.

Ann Neurol. 2012 Jun;71(6):776-84. doi: 10.1002/ana.22629. Epub 2011 Nov 14.

50.

Characterizing the behavioral effects of nerve agent-induced seizure activity in rats: increased startle reactivity and perseverative behavior.

Langston JL, Wright LK, Connis N, Lumley LA.

Pharmacol Biochem Behav. 2012 Jan;100(3):382-91. doi: 10.1016/j.pbb.2011.09.011. Epub 2011 Oct 1.

PMID:
21983492

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