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Items: 1 to 50 of 1869

1.

A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery.

Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT.

Hear Res. 2018 Apr 5. pii: S0378-5955(17)30640-8. doi: 10.1016/j.heares.2018.03.026. [Epub ahead of print]

PMID:
29661614
2.

Caffeine-catalyzed gels.

DiCiccio AM, Lee YL, Glettig DL, Walton ESE, de la Serna EL, Montgomery VA, Grant TM, Langer R, Traverso G.

Biomaterials. 2018 Apr 6;170:127-135. doi: 10.1016/j.biomaterials.2018.04.010. [Epub ahead of print]

PMID:
29660635
3.

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ.

Cell. 2018 Apr 19;173(3):624-633.e8. doi: 10.1016/j.cell.2018.03.026. Epub 2018 Apr 12.

PMID:
29656892
4.

Accuracy of Bioelectrical Impedance Analysis in Estimated Longitudinal Fat-Free Mass Changes in Male Army Cadets.

Langer RD, Matias CN, Borges JH, Cirolini VX, Páscoa MA, Guerra-Júnior G, Gonçalves EM.

Mil Med. 2018 Mar 26. doi: 10.1093/milmed/usx223. [Epub ahead of print]

PMID:
29590470
5.

Surface tension-assisted additive manufacturing.

Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R.

Nat Commun. 2018 Mar 22;9(1):1184. doi: 10.1038/s41467-018-03391-w.

6.

Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas.

Kröll D, Noser L, Erdem S, Storni F, Arnold D, Dislich B, Zlobec I, Candinas D, Seiler CA, Langer R.

Surg Oncol. 2018 Mar;27(1):100-105. doi: 10.1016/j.suronc.2017.12.005. Epub 2018 Jan 31.

PMID:
29549896
7.

Design and Synthesis of Waterborne Polyurethanes.

Kang SY, Ji Z, Tseng LF, Turner SA, Villanueva DA, Johnson R, Albano A, Langer R.

Adv Mater. 2018 Mar 15:e1706237. doi: 10.1002/adma.201706237. [Epub ahead of print]

PMID:
29543353
8.

Defining Outcomes for β-Cell Replacement Therapy in the Treatment of Diabetes: a Consensus Report on the Igls Criteria from the IPITA/EPITA Opinion Leaders Workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transplantation. 2018 Mar 9. doi: 10.1097/TP.0000000000002158. [Epub ahead of print]

PMID:
29528967
9.

Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams.

Traverso G, Kirtane AR, Schoellhammer CM, Langer R.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4156-4163. doi: 10.1002/anie.201712512. Epub 2018 Mar 9. Review.

PMID:
29520902
10.

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse.

Kauffman KJ, Oberli MA, Dorkin JR, Hurtado JE, Kaczmarek JC, Bhadani S, Wyckoff J, Langer R, Jaklenec A, Anderson DG.

Mol Ther Nucleic Acids. 2018 Mar 2;10:55-63. doi: 10.1016/j.omtn.2017.11.005. Epub 2017 Nov 21.

11.

Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents.

McHugh KJ, Jing L, Behrens AM, Jayawardena S, Tang W, Gao M, Langer R, Jaklenec A.

Adv Mater. 2018 Feb 22. doi: 10.1002/adma.201706356. [Epub ahead of print] Review.

PMID:
29468747
12.

Carbodiphosphorane-based nickel pincer complexes and their (de)protonated analogues: dimerisation, ligand tautomers and proton affinities.

Maser L, Herritsch J, Langer R.

Dalton Trans. 2018 Feb 22. doi: 10.1039/c7dt04930g. [Epub ahead of print]

PMID:
29468238
13.

Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transpl Int. 2018 Apr;31(4):343-352. doi: 10.1111/tri.13138. Review.

PMID:
29453879
14.

Drug delivery across length scales.

Delcassian D, Patel AK, Cortinas AB, Langer R.

J Drug Target. 2018 Feb 20:1-15. doi: 10.1080/1061186X.2018.1438440. [Epub ahead of print]

PMID:
29415575
15.

PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy.

Boxberg M, Steiger K, Lenze U, Rechl H, von Eisenhart-Rothe R, Wörtler K, Weichert W, Langer R, Specht K.

Oncoimmunology. 2017 Nov 20;7(3):e1389366. doi: 10.1080/2162402X.2017.1389366. eCollection 2018.

PMID:
29399389
16.

Umpolung at Boron: Ancillary-Ligand-Induced Formation of Boron-Based Donor Ligands from Phosphine-Boranes.

Vondung L, Alig L, Ballmann M, Langer R.

Chemistry. 2018 Feb 1. doi: 10.1002/chem.201705847. [Epub ahead of print]

PMID:
29389052
17.

Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.

Guimarães PPG, Gaglione S, Sewastianik T, Carrasco RD, Langer R, Mitchell MJ.

ACS Nano. 2018 Feb 27;12(2):912-931. doi: 10.1021/acsnano.7b05876. Epub 2018 Feb 6.

PMID:
29378114
18.

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.

Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG.

Nat Chem Biol. 2018 Mar;14(3):311-316. doi: 10.1038/nchembio.2559. Epub 2018 Jan 29.

19.

Miniaturized neural system for chronic, local intracerebral drug delivery.

Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaan2742. doi: 10.1126/scitranslmed.aan2742.

PMID:
29367347
20.

Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy.

Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G.

Nat Commun. 2018 Jan 9;9(1):2. doi: 10.1038/s41467-017-02294-6.

21.

Circulating Magnetic Microbubbles for Localized Real-Time Control of Drug Delivery by Ultrasonography-Guided Magnetic Targeting and Ultrasound.

Chertok B, Langer R.

Theranostics. 2018 Jan 1;8(2):341-357. doi: 10.7150/thno.20781. eCollection 2018.

22.

Erratum: Glucose-responsive insulin by molecular and physical design.

Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS.

Nat Chem. 2017 Dec 19;10(1):109. doi: 10.1038/nchem.2898.

PMID:
29256502
23.

Molecular Rotors for Universal Quantitation of Nanoscale Hydrophobic Interfaces in Microplate Format.

Bisso PW, Tai M, Katepalli H, Bertrand N, Blankschtein D, Langer R.

Nano Lett. 2018 Jan 10;18(1):618-628. doi: 10.1021/acs.nanolett.7b04877. Epub 2017 Dec 22.

PMID:
29244511
24.

Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.

Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH.

Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211a.

PMID:
29220013
25.

Adaptive thermogenesis and changes in body composition and physical fitness in army cadets.

Borges JH, Hunter GR, Silva AM, Cirolini VX, Langer RD, Páscoa MA, Guerra G Jr, Gonçalves EM.

J Sports Med Phys Fitness. 2017 Dec 1. doi: 10.23736/S0022-4707.17.08066-5. [Epub ahead of print]

PMID:
29199788
26.

Prediction of Broad-Spectrum Pathogen Attachment to Coating Materials for Biomedical Devices.

Mikulskis P, Hook A, Dundas AA, Irvine D, Sanni O, Anderson D, Langer R, Alexander MR, Williams P, Winkler DA.

ACS Appl Mater Interfaces. 2018 Jan 10;10(1):139-149. doi: 10.1021/acsami.7b14197. Epub 2018 Jan 2.

PMID:
29191009
27.

The development of bioresorbable composite polymeric implants with high mechanical strength.

Sharma U, Concagh D, Core L, Kuang Y, You C, Pham Q, Zugates G, Busold R, Webber S, Merlo J, Langer R, Whitesides GM, Palasis M.

Nat Mater. 2018 Jan;17(1):96-103. doi: 10.1038/nmat5016. Epub 2017 Nov 20.

PMID:
29180778
28.

Long-term dopamine neurochemical monitoring in primates.

Schwerdt HN, Shimazu H, Amemori KI, Amemori S, Tierney PL, Gibson DJ, Hong S, Yoshida T, Langer R, Cima MJ, Graybiel AM.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13260-13265. doi: 10.1073/pnas.1713756114. Epub 2017 Nov 20.

PMID:
29158415
29.

Ultrasound-triggered local anaesthesia.

Rwei AY, Paris JL, Wang B, Wang W, Axon CD, Vallet-Regí M, Langer R, Kohane DS.

Nat Biomed Eng. 2017;1:644-653. doi: 10.1038/s41551-017-0117-6. Epub 2017 Aug 9.

30.

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG.

Nat Biotechnol. 2017 Dec;35(12):1179-1187. doi: 10.1038/nbt.4005. Epub 2017 Nov 13.

31.

Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells.

Tong Z, Martyn K, Yang A, Yin X, Mead BE, Joshi N, Sherman NE, Langer RS, Karp JM.

Biomaterials. 2018 Feb;154:60-73. doi: 10.1016/j.biomaterials.2017.10.038. Epub 2017 Oct 26.

PMID:
29120819
32.

Follow-up chest radiographic findings in patients with MERS-CoV after recovery.

Das KM, Lee EY, Singh R, Enani MA, Al Dossari K, Van Gorkom K, Larsson SG, Langer RD.

Indian J Radiol Imaging. 2017 Jul-Sep;27(3):342-349. doi: 10.4103/ijri.IJRI_469_16.

33.

Defining optimal permeant characteristics for ultrasound-mediated gastrointestinal delivery.

Schoellhammer CM, Chen Y, Cleveland C, Minahan D, Bensel T, Park JY, Saxton S, Lee YL, Booth L, Langer R, Traverso G.

J Control Release. 2017 Dec 28;268:113-119. doi: 10.1016/j.jconrel.2017.10.023. Epub 2017 Oct 16.

PMID:
29051063
34.

Engineering and physical sciences in oncology: challenges and opportunities.

Mitchell MJ, Jain RK, Langer R.

Nat Rev Cancer. 2017 Nov;17(11):659-675. doi: 10.1038/nrc.2017.83. Epub 2017 Oct 13. Review.

PMID:
29026204
35.

Erratum: Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.

Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ.

Sci Rep. 2017 Oct 9;7(1):12812. doi: 10.1038/s41598-017-12312-8.

36.

Ambireactive (R3 P)2 BH2 Groups Facilitating Temperature-Switchable Bond Activation by an Iron Complex.

Vondung L, Sattler LE, Langer R.

Chemistry. 2018 Jan 26;24(6):1358-1364. doi: 10.1002/chem.201704018. Epub 2017 Dec 15.

PMID:
28991392
37.

Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome.

Kunzke T, Balluff B, Feuchtinger A, Buck A, Langer R, Luber B, Lordick F, Zitzelsberger H, Aichler M, Walch A.

Oncotarget. 2017 Jul 10;8(40):68012-68025. doi: 10.18632/oncotarget.19137. eCollection 2017 Sep 15.

38.

Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics.

Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC.

Nat Commun. 2017 Oct 3;8(1):777. doi: 10.1038/s41467-017-00600-w.

39.

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition.

Aday S, Zoldan J, Besnier M, Carreto L, Saif J, Fernandes R, Santos T, Bernardino L, Langer R, Emanueli C, Ferreira L.

Nat Commun. 2017 Sep 29;8(1):747. doi: 10.1038/s41467-017-00746-7.

40.

Living Biomaterials.

Tibbitt MW, Langer R.

Acc Chem Res. 2017 Mar 21;50(3):508-513. doi: 10.1021/acs.accounts.6b00499.

PMID:
28945422
41.

Glucose-responsive insulin by molecular and physical design.

Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS.

Nat Chem. 2017 Sep 22;9(10):937-943. doi: 10.1038/nchem.2857. Erratum in: Nat Chem. 2017 Dec 19;10 (1):109.

PMID:
28937662
42.

High-throughput Nuclear Delivery and Rapid Expression of DNA via Mechanical and Electrical Cell-Membrane Disruption.

Ding X, Stewart M, Sharei A, Weaver JC, Langer RS, Jensen KF.

Nat Biomed Eng. 2017;1. pii: 0039. doi: 10.1038/s41551-017-0039. Epub 2017 Mar 9.

43.

Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy.

Langer R, Becker K.

Virchows Arch. 2018 Feb;472(2):175-186. doi: 10.1007/s00428-017-2232-x. Epub 2017 Sep 16. Review.

PMID:
28918544
44.

Fabrication of fillable microparticles and other complex 3D microstructures.

McHugh KJ, Nguyen TD, Linehan AR, Yang D, Behrens AM, Rose S, Tochka ZL, Tzeng SY, Norman JJ, Anselmo AC, Xu X, Tomasic S, Taylor MA, Lu J, Guarecuco R, Langer R, Jaklenec A.

Science. 2017 Sep 15;357(6356):1138-1142. doi: 10.1126/science.aaf7447.

PMID:
28912242
45.

Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.

Niklaus M, Adams O, Berezowska S, Zlobec I, Graber F, Slotta-Huspenina J, Nitsche U, Rosenberg R, Tschan MP, Langer R.

Oncotarget. 2017 May 2;8(33):54604-54615. doi: 10.18632/oncotarget.17554. eCollection 2017 Aug 15.

46.

Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases.

Keller MD, Neppl C, Irmak Y, Hall SR, Schmid RA, Langer R, Berezowska S.

Mod Pathol. 2018 Jan;31(1):101-110. doi: 10.1038/modpathol.2017.111. Epub 2017 Sep 8.

PMID:
28884747
47.

Multiscale technologies for treatment of ischemic cardiomyopathy.

Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC.

Nat Nanotechnol. 2017 Sep 6;12(9):845-855. doi: 10.1038/nnano.2017.167. Review.

48.

Menopausal hormone therapy for primary prevention: why the USPSTF is wrong.

Langer RD, Simon JA, Pines A, Lobo RA, Hodis HN, Pickar JH, Archer DF, Sarrel PM, Utian WH.

Menopause. 2017 Oct;24(10):1101-1112. doi: 10.1097/GME.0000000000000983. No abstract available.

PMID:
28872490
49.

Quality Standards for Herbal Drugs and Herbal Drug Preparations - Appropriate or Improvements Necessary?

Länger R, Stöger E, Kubelka W, Helliwell K.

Planta Med. 2017 Aug 29. doi: 10.1055/s-0043-118534. [Epub ahead of print]

PMID:
28850958
50.

Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA.

Martinez-Moreno M, O'Shea TM, Zepecki JP, Olaru A, Ness JK, Langer R, Tapinos N.

Cell Rep. 2017 Aug 22;20(8):1950-1963. doi: 10.1016/j.celrep.2017.07.068.

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