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Items: 22

1.

Comparison of proteomic quantification approaches for hepatic drug transporters: multiplexed global quantitation correlates with targeted proteomic quantitation.

Vildhede A, Nguyen C, Erickson BK, Kunz RC, Jones R, Kimoto E, Bourbonais F, Rodrigues AD, Varma MV.

Drug Metab Dispos. 2018 Feb 8. pii: dmd.117.079285. doi: 10.1124/dmd.117.079285. [Epub ahead of print]

PMID:
29439128
2.

S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy.

Qian Q, Zhang Z, Orwig A, Chen S, Ding WX, Xu Y, Kunz RC, Lind NRL, Stamler JS, Yang L.

Diabetes. 2018 Feb;67(2):193-207. doi: 10.2337/db17-0223. Epub 2017 Oct 26.

PMID:
29074597
3.

Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.

Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, Ho HH.

Elife. 2017 Sep 8;6. pii: e26509. doi: 10.7554/eLife.26509.

4.

Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.

Yin S, Lopez-Gonzalez R, Kunz RC, Gangopadhyay J, Borufka C, Gygi SP, Gao FB, Reed R.

Cell Rep. 2017 Jun 13;19(11):2244-2256. doi: 10.1016/j.celrep.2017.05.056.

5.

METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.

Yang L, Calay ES, Fan J, Arduini A, Kunz RC, Gygi SP, Yalcin A, Fu S, Hotamisligil GS.

Science. 2015 Jul 31;349(6247):500-6. doi: 10.1126/science.aaa0079.

6.

A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity.

Nakamura T, Kunz RC, Zhang C, Kimura T, Yuan CL, Baccaro B, Namiki Y, Gygi SP, Hotamisligil GS.

Cell Rep. 2015 Apr 14;11(2):295-307. doi: 10.1016/j.celrep.2015.03.021. Epub 2015 Apr 2.

7.

Increasing throughput in targeted proteomics assays: 54-plex quantitation in a single mass spectrometry run.

Everley RA, Kunz RC, McAllister FE, Gygi SP.

Anal Chem. 2013 Jun 4;85(11):5340-6. doi: 10.1021/ac400845e. Epub 2013 May 23.

PMID:
23662842
8.

A high-throughput, multiplexed kinase assay using a benchtop orbitrap mass spectrometer to investigate the effect of kinase inhibitors on kinase signaling pathways.

Kunz RC, McAllister FE, Rush J, Gygi SP.

Anal Chem. 2012 Jul 17;84(14):6233-9. doi: 10.1021/ac301116z. Epub 2012 Jul 3.

PMID:
22724890
9.

Cdc7-Dbf4 is a gene-specific regulator of meiotic transcription in yeast.

Lo HC, Kunz RC, Chen X, Marullo A, Gygi SP, Hollingsworth NM.

Mol Cell Biol. 2012 Jan;32(2):541-57. doi: 10.1128/MCB.06032-11. Epub 2011 Nov 21.

10.
11.

Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate.

Li X, Telser J, Kunz RC, Hoffman BM, Gerfen G, Ragsdale SW.

Biochemistry. 2010 Aug 17;49(32):6866-76. doi: 10.1021/bi100650m.

12.

Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation.

Niu H, Wan L, Busygina V, Kwon Y, Allen JA, Li X, Kunz RC, Kubota K, Wang B, Sung P, Shokat KM, Gygi SP, Hollingsworth NM.

Mol Cell. 2009 Nov 13;36(3):393-404. doi: 10.1016/j.molcel.2009.09.029.

13.

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.

Kubota K, Anjum R, Yu Y, Kunz RC, Andersen JN, Kraus M, Keilhack H, Nagashima K, Krauss S, Paweletz C, Hendrickson RC, Feldman AS, Wu CL, Rush J, Villén J, Gygi SP.

Nat Biotechnol. 2009 Oct;27(10):933-40. doi: 10.1038/nbt.1566. Epub 2009 Oct 4.

14.

Characterization of the thioether product formed from the thiolytic cleavage of the alkyl-nickel bond in methyl-coenzyme M reductase.

Kunz RC, Dey M, Ragsdale SW.

Biochemistry. 2008 Feb 26;47(8):2661-7. doi: 10.1021/bi701942w. Epub 2008 Jan 26.

PMID:
18220418
15.

Characterization of alkyl-nickel adducts generated by reaction of methyl-coenzyme m reductase with brominated acids.

Dey M, Kunz RC, Lyons DM, Ragsdale SW.

Biochemistry. 2007 Oct 23;46(42):11969-78. Epub 2007 Sep 29.

16.

Biochemical and spectroscopic studies of the electronic structure and reactivity of a methyl-Ni species formed on methyl-coenzyme M reductase.

Dey M, Telser J, Kunz RC, Lees NS, Ragsdale SW, Hoffman BM.

J Am Chem Soc. 2007 Sep 12;129(36):11030-2. Epub 2007 Aug 21. No abstract available.

PMID:
17711283
17.

Spectroscopic and computational studies of reduction of the metal versus the tetrapyrrole ring of coenzyme F430 from methyl-coenzyme M reductase.

Dey M, Kunz RC, Van Heuvelen KM, Craft JL, Horng YC, Tang Q, Bocian DF, George SJ, Brunold TC, Ragsdale SW.

Biochemistry. 2006 Oct 3;45(39):11915-33.

18.

Spectroscopic and kinetic studies of the reaction of bromopropanesulfonate with methyl-coenzyme M reductase.

Kunz RC, Horng YC, Ragsdale SW.

J Biol Chem. 2006 Nov 10;281(45):34663-76. Epub 2006 Sep 11.

19.

Effect of methanobactin on the activity and electron paramagnetic resonance spectra of the membrane-associated methane monooxygenase in Methylococcus capsulatus Bath.

Choi DW, Antholine WE, Do YS, Semrau JD, Kisting CJ, Kunz RC, Campbell D, Rao V, Hartsel SC, DiSpirito AA.

Microbiology. 2005 Oct;151(Pt 10):3417-26.

PMID:
16207923
20.

Footlift asymmetry during obstacle avoidance in high-risk elderly.

Di Fabio RP, Kurszewski WM, Jorgenson EE, Kunz RC.

J Am Geriatr Soc. 2004 Dec;52(12):2088-93.

PMID:
15571548
21.

The membrane-associated methane monooxygenase (pMMO) and pMMO-NADH:quinone oxidoreductase complex from Methylococcus capsulatus Bath.

Choi DW, Kunz RC, Boyd ES, Semrau JD, Antholine WE, Han JI, Zahn JA, Boyd JM, de la Mora AM, DiSpirito AA.

J Bacteriol. 2003 Oct;185(19):5755-64.

22.

Membrane-associated quinoprotein formaldehyde dehydrogenase from Methylococcus capsulatus Bath.

Zahn JA, Bergmann DJ, Boyd JM, Kunz RC, DiSpirito AA.

J Bacteriol. 2001 Dec;183(23):6832-40.

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