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Items: 15

1.

Gut microbiota and Toll-like receptors set the stage for cytokine-mediated failure of antibacterial responses in the fibrotic liver.

Kuntzen C, Schwabe RF.

Gut. 2017 Mar;66(3):396-398. doi: 10.1136/gutjnl-2016-312486. Epub 2016 Sep 21. No abstract available.

PMID:
27654586
2.

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

Siegmund SV, Schlosser M, Schildberg FA, Seki E, De Minicis S, Uchinami H, Kuntzen C, Knolle PA, Strassburg CP, Schwabe RF.

PLoS One. 2016 Mar 3;11(3):e0150893. doi: 10.1371/journal.pone.0150893. eCollection 2016.

3.

Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.

Vallabhapurapu SD, Noothi SK, Pullum DA, Lawrie CH, Pallapati R, Potluri V, Kuntzen C, Khan S, Plas DR, Orlowski RZ, Chesi M, Kuehl WM, Bergsagel PL, Karin M, Vallabhapurapu S.

Nat Commun. 2015 Oct 12;6:8428. doi: 10.1038/ncomms9428.

PMID:
26455434
4.

Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.

Stebbins JL, De SK, Pavlickova P, Chen V, Machleidt T, Chen LH, Kuntzen C, Kitada S, Karin M, Pellecchia M.

J Med Chem. 2011 Sep 22;54(18):6206-14. doi: 10.1021/jm200479c. Epub 2011 Aug 23.

5.

Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation.

He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, Sieghart W, Peck-Radosavljevic M, Leffert HL, Karin M.

Cancer Cell. 2010 Mar 16;17(3):286-97. doi: 10.1016/j.ccr.2009.12.048.

6.

Identification of a new JNK inhibitor targeting the JNK-JIP interaction site.

Stebbins JL, De SK, Machleidt T, Becattini B, Vazquez J, Kuntzen C, Chen LH, Cellitti JF, Riel-Mehan M, Emdadi A, Solinas G, Karin M, Pellecchia M.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16809-13. doi: 10.1073/pnas.0805677105. Epub 2008 Oct 15.

7.

A method for isolating prosurvival targets of NF-kappaB/Rel transcription factors.

Kuntzen C, Zazzeroni F, Pham CG, Papa S, Bubici C, Knabb JR, Franzoso G.

Methods Mol Biol. 2007;399:99-124. Review.

PMID:
18309928
8.

Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs.

Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C, Franzoso G.

Mol Cell Biol. 2007 Jun;27(11):3920-35. Epub 2007 Apr 2.

9.

P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes.

De Toni EN, Kuntzen C, Gerbes AL, Thasler WE, Sonuc N, Mucha SR, Camaj P, Bruns C, Göke B, Eichhorst ST.

J Hepatol. 2007 Apr;46(4):682-91. Epub 2006 Nov 27.

PMID:
17224200
10.

The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.

Papa S, Bubici C, Zazzeroni F, Pham CG, Kuntzen C, Knabb JR, Dean K, Franzoso G.

Cell Death Differ. 2006 May;13(5):712-29. Review.

11.

Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest.

Kuntzen C, Sonuc N, De Toni EN, Opelz C, Mucha SR, Gerbes AL, Eichhorst ST.

Cancer Res. 2005 Aug 1;65(15):6780-8.

12.

Use of a mixed endothelin receptor antagonist in portopulmonary hypertension: a safe and effective therapy?

Kuntzen C, Gülberg V, Gerbes AL.

Gastroenterology. 2005 Jan;128(1):164-8.

PMID:
15633133
13.

HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway.

Finzer P, Krueger A, Stöhr M, Brenner D, Soto U, Kuntzen C, Krammer PH, Rösl F.

Oncogene. 2004 Jun 17;23(28):4807-17.

PMID:
15077164
14.

Growth arrest of HPV-positive cells after histone deacetylase inhibition is independent of E6/E7 oncogene expression.

Finzer P, Ventz R, Kuntzen C, Seibert N, Soto U, Rösl F.

Virology. 2002 Dec 20;304(2):265-73.

15.

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