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Items: 1 to 50 of 180

1.

The influence of lead nanoparticles on the morpho-functional changes of rat liver during the postexposure period.

Aleksiichuk V, Omelchuk S, Sokurenko L, Kaminsky R, Kovalchuk O, Chaikovsky Y.

Microsc Res Tech. 2018 Apr 13. doi: 10.1002/jemt.23036. [Epub ahead of print]

PMID:
29652104
2.

Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization.

Cortese F, Klokov D, Osipov A, Stefaniak J, Moskalev A, Schastnaya J, Cantor C, Aliper A, Mamoshina P, Ushakov I, Sapetsky A, Vanhaelen Q, Alchinova I, Karganov M, Kovalchuk O, Wilkins R, Shtemberg A, Moreels M, Baatout S, Izumchenko E, de Magalhães JP, Artemov AV, Costes SV, Beheshti A, Mao XW, Pecaut MJ, Kaminskiy D, Ozerov IV, Scheibye-Knudsen M, Zhavoronkov A.

Oncotarget. 2018 Feb 12;9(18):14692-14722. doi: 10.18632/oncotarget.24461. eCollection 2018 Mar 6. Review.

3.
4.

Adverse effects of paternal chemotherapy exposure on the progeny brain: intergenerational chemobrain.

Kovalchuk A, Ilnytskyy Y, Woycicki R, Rodriguez-Juarez R, Metz GAS, Kovalchuk O.

Oncotarget. 2018 Jan 23;9(11):10069-10082. doi: 10.18632/oncotarget.24311. eCollection 2018 Feb 9.

5.

Growth of Malignant Non-CNS Tumors Alters Brain Metabolome.

Kovalchuk A, Nersisyan L, Mandal R, Wishart D, Mancini M, Sidransky D, Kolb B, Kovalchuk O.

Front Genet. 2018 Feb 20;9:41. doi: 10.3389/fgene.2018.00041. eCollection 2018.

6.

Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to X-ray irradiation.

Sorokin M, Kholodenko R, Grekhova A, Suntsova M, Pustovalova M, Vorobyeva N, Kholodenko I, Malakhova G, Garazha A, Nedoluzhko A, Vasilov R, Poddubskaya E, Kovalchuk O, Adamyan L, Prassolov V, Allina D, Kuzmin D, Ignatev K, Osipov A, Buzdin A.

Oncotarget. 2017 Dec 27;9(4):5111-5124. doi: 10.18632/oncotarget.23700. eCollection 2018 Jan 12.

7.

Population specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern European patient populations.

Mamoshina P, Kochetov K, Putin E, Cortese F, Aliper A, Lee WS, Ahn SM, Uhn L, Skjodt N, Kovalchuk O, Scheibye-Knudsen M, Zhavoronkov A.

J Gerontol A Biol Sci Med Sci. 2018 Jan 11. doi: 10.1093/gerona/gly005. [Epub ahead of print]

PMID:
29340580
8.

Global transcriptome profiling of mild relapsing-remitting versus primary progressive multiple sclerosis.

Koch MW, Ilnytskyy Y, Golubov A, Metz LM, Yong VW, Kovalchuk O.

Eur J Neurol. 2018 Apr;25(4):651-658. doi: 10.1111/ene.13565. Epub 2018 Feb 13.

PMID:
29316044
9.

A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Borisov N, Tkachev V, Suntsova M, Kovalchuk O, Zhavoronkov A, Muchnik I, Buzdin A.

Cell Cycle. 2018;17(4):486-491. doi: 10.1080/15384101.2017.1417706. Epub 2018 Jan 17.

PMID:
29251172
10.

Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice.

Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Katz A, Sidransky D, Kolb B, Kovalchuk O.

Oncotarget. 2017 Aug 3;8(51):88276-88293. doi: 10.18632/oncotarget.19835. eCollection 2017 Oct 24.

11.

Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas.

Petrov I, Suntsova M, Ilnitskaya E, Roumiantsev S, Sorokin M, Garazha A, Spirin P, Lebedev T, Gaifullin N, Larin S, Kovalchuk O, Konovalov D, Prassolov V, Roumiantsev A, Buzdin A.

Oncotarget. 2017 Jul 28;8(48):83768-83780. doi: 10.18632/oncotarget.19662. eCollection 2017 Oct 13.

12.

Epigenetic Regulation of Cellular Senescence and Aging.

Sidler C, Kovalchuk O, Kovalchuk I.

Front Genet. 2017 Sep 26;8:138. doi: 10.3389/fgene.2017.00138. eCollection 2017. Review.

13.

DYNAMICS OF MORPHOLOGICAL CHANGES OF RATS' ADENOHYPOPHYSIS IN BURN DISEASE.

Kovalchuk O, Cherkasov E, Dzevulska I, Kaminsky R, Korsak A, Sokurenko L.

Georgian Med News. 2017 Sep;(270):104-108.

PMID:
28972493
14.

Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors.

Spirin P, Lebedev T, Orlova N, Morozov A, Poymenova N, Dmitriev SE, Buzdin A, Stocking C, Kovalchuk O, Prassolov V.

Oncotarget. 2017 Jun 16;8(34):56991-57002. doi: 10.18632/oncotarget.18503. eCollection 2017 Aug 22.

15.

Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data.

Borisov N, Suntsova M, Sorokin M, Garazha A, Kovalchuk O, Aliper A, Ilnitskaya E, Lezhnina K, Korzinkin M, Tkachev V, Saenko V, Saenko Y, Sokov DG, Gaifullin NM, Kashintsev K, Shirokorad V, Shabalina I, Zhavoronkov A, Mishra B, Cantor CR, Buzdin A.

Cell Cycle. 2017 Oct 2;16(19):1810-1823. doi: 10.1080/15384101.2017.1361068. Epub 2017 Aug 21.

PMID:
28825872
16.

Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice.

Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Shpyleva S, Melnyk S, Pogribny I, Katz A, Sidransky D, Kovalchuk O, Kolb B.

Aging (Albany NY). 2017 Jul 29;9(7):1660-1676. doi: 10.18632/aging.101243.

17.

A review of the biomedical innovations for healthy longevity.

Moskalev A, Anisimov V, Aliper A, Artemov A, Asadullah K, Belsky D, Baranova A, de Grey A, Dixit VD, Debonneuil E, Dobrovolskaya E, Fedichev P, Fedintsev A, Fraifeld V, Franceschi C, Freer R, Fülöp T, Feige J, Gems D, Gladyshev V, Gorbunova V, Irincheeva I, Jager S, Jazwinski SM, Kaeberlein M, Kennedy B, Khaltourina D, Kovalchuk I, Kovalchuk O, Kozin S, Kulminski A, Lashmanova E, Lezhnina K, Liu GH, Longo V, Mamoshina P, Maslov A, Pedro de Magalhaes J, Mitchell J, Mitnitski A, Nikolsky Y, Ozerov I, Pasyukova E, Peregudova D, Popov V, Proshkina E, Putin E, Rogaev E, Rogina B, Schastnaya J, Seluanov A, Shaposhnikov M, Simm A, Skulachev V, Skulachev M, Solovev I, Spindler S, Stefanova N, Suh Y, Swick A, Tower J, Gudkov AV, Vijg J, Voronkov A, West M, Wagner W, Yashin A, Zemskaya N, Zhumadilov Z, Zhavoronkov A.

Aging (Albany NY). 2017 Jan 29;9(1):7-25. doi: 10.18632/aging.101163. No abstract available.

18.

Fractionated low-dose exposure to ionizing radiation leads to DNA damage, epigenetic dysregulation, and behavioral impairment.

Koturbash I, Jadavji NM, Kutanzi K, Rodriguez-Juarez R, Kogosov D, Metz GAS, Kovalchuk O.

Environ Epigenet. 2017 Jan 31;2(4):dvw025. doi: 10.1093/eep/dvw025. eCollection 2016 Dec.

19.

Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts.

Buzdin AA, Artcibasova AV, Fedorova NF, Suntsova MV, Garazha AV, Sorokin MI, Allina D, Shalatonin M, Borisov NM, Zhavoronkov AA, Kovalchuk I, Kovalchuk O, Kushch AA.

Cell Cycle. 2016 Dec 16;15(24):3378-3389. doi: 10.1080/15384101.2016.1241928.

20.

Molecular pathway activation features of pediatric acute myeloid leukemia (AML) and acute lymphoblast leukemia (ALL) cells.

Petrov I, Suntsova M, Mutorova O, Sorokin M, Garazha A, Ilnitskaya E, Spirin P, Larin S, Kovalchuk O, Prassolov V, Zhavoronkov A, Roumiantsev A, Buzdin A.

Aging (Albany NY). 2016 Nov 19;8(11):2936-2947. doi: 10.18632/aging.101102.

21.

Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer.

Krishnan P, Ghosh S, Graham K, Mackey JR, Kovalchuk O, Damaraju S.

Oncotarget. 2016 Jun 21;7(25):37944-37956. doi: 10.18632/oncotarget.9272.

22.

Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner.

Koturbash I, Merrifield M, Kovalchuk O.

Int J Radiat Biol. 2017 Feb;93(2):148-155. doi: 10.1080/09553002.2017.1231943. Epub 2016 Oct 19.

PMID:
27758128
23.

Profiling of Small Nucleolar RNAs by Next Generation Sequencing: Potential New Players for Breast Cancer Prognosis.

Krishnan P, Ghosh S, Wang B, Heyns M, Graham K, Mackey JR, Kovalchuk O, Damaraju S.

PLoS One. 2016 Sep 15;11(9):e0162622. doi: 10.1371/journal.pone.0162622. eCollection 2016.

24.

Genome-wide profiling of transfer RNAs and their role as novel prognostic markers for breast cancer.

Krishnan P, Ghosh S, Wang B, Heyns M, Li D, Mackey JR, Kovalchuk O, Damaraju S.

Sci Rep. 2016 Sep 8;6:32843. doi: 10.1038/srep32843.

25.

Radiological characterization and evaluation of high volume bauxite residue alkali activated concretes.

Croymans T, Schroeyers W, Krivenko P, Kovalchuk O, Pasko A, Hult M, Marissens G, Lutter G, Schreurs S.

J Environ Radioact. 2017 Mar;168:21-29. doi: 10.1016/j.jenvrad.2016.08.013. Epub 2016 Aug 21.

26.

Mammary gland and radiation: Knowns and unknowns.

Luzhna L, Kovalchuk O.

Cell Cycle. 2016 Aug 2;15(15):1975-6. doi: 10.1080/15384101.2016.1170262. Epub 2016 Jul 8.

27.

Profound and Sexually Dimorphic Effects of Clinically-Relevant Low Dose Scatter Irradiation on the Brain and Behavior.

Kovalchuk A, Mychasiuk R, Muhammad A, Hossain S, Ilnytskyy Y, Ghose A, Kirkby C, Ghasroddashti E, Kolb B, Kovalchuk O.

Front Behav Neurosci. 2016 Jun 3;10:84. doi: 10.3389/fnbeh.2016.00084. eCollection 2016.

28.

High and low dose radiation effects on mammary adenocarcinoma cells - an epigenetic connection.

Luzhna L, Filkowski J, Kovalchuk O.

Oncoscience. 2016 Mar 10;3(3-4):88-97. doi: 10.18632/oncoscience.298. eCollection 2016.

29.

Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection.

Kovalchuk A, Rodriguez-Juarez R, Ilnytskyy Y, Byeon B, Shpyleva S, Melnyk S, Pogribny I, Kolb B, Kovalchuk O.

Aging (Albany NY). 2016 Apr;8(4):697-711. doi: 10.18632/aging.100920.

30.

Circadian-disruption-induced gene expression changes in rodent mammary tissues.

Kochan DZ, Ilnytskyy Y, Golubov A, Deibel SH, McDonald RJ, Kovalchuk O.

Oncoscience. 2016 Feb 12;3(2):58-70. eCollection 2016.

31.

Circadian disruption-induced breast cancer--knowns and unknowns.

Kochan DZ, Kovalchuk O.

Cell Cycle. 2016;15(5):613-4. doi: 10.1080/15384101.2015.1131526. Epub 2016 Jan 6. No abstract available.

32.

Liver irradiation causes distal bystander effects in the rat brain and affects animal behaviour.

Kovalchuk A, Mychasiuk R, Muhammad A, Hossain S, Ilnytskyy S, Ghose A, Kirkby C, Ghasroddashti E, Kovalchuk O, Kolb B.

Oncotarget. 2016 Jan 26;7(4):4385-98. doi: 10.18632/oncotarget.6596.

33.

Towards understanding the breast cancer epigenome: a comparison of genome-wide DNA methylation and gene expression data.

Singhal SK, Usmani N, Michiels S, Metzger-Filho O, Saini KS, Kovalchuk O, Parliament M.

Oncotarget. 2016 Jan 19;7(3):3002-17. doi: 10.18632/oncotarget.6503.

34.

Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer.

Krishnan P, Ghosh S, Wang B, Li D, Narasimhan A, Berendt R, Graham K, Mackey JR, Kovalchuk O, Damaraju S.

BMC Genomics. 2015 Sep 29;16:735. doi: 10.1186/s12864-015-1899-0.

35.

Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer.

Heyns M, Kovalchuk O.

Oncotarget. 2015 Sep 15;6(27):23055-7.

36.

Epigenetic alterations in the suprachiasmatic nucleus and hippocampus contribute to age-related cognitive decline.

Deibel SH, Zelinski EL, Keeley RJ, Kovalchuk O, McDonald RJ.

Oncotarget. 2015 Sep 15;6(27):23181-203. Review.

37.

Circadian disruption and breast cancer: an epigenetic link?

Kochan DZ, Kovalchuk O.

Oncotarget. 2015 Jul 10;6(19):16866-82. Review.

38.

Circadian disruption-induced microRNAome deregulation in rat mammary gland tissues.

Kochan DZ, Ilnytskyy Y, Golubov A, Deibel SH, McDonald RJ, Kovalchuk O.

Oncoscience. 2015 Apr 26;2(4):428-42. eCollection 2015.

39.

A suppressive role of ionizing radiation-responsive miR-29c in the development of liver carcinoma via targeting WIP1.

Wang B, Li D, Sidler C, Rodriguez-Juarez R, Singh N, Heyns M, Ilnytskyy Y, Bronson RT, Kovalchuk O.

Oncotarget. 2015 Apr 30;6(12):9937-50.

41.

Gene expression and epigenetic profiles of mammary gland tissue: insight into the differential predisposition of four rat strains to mammary gland cancer.

Luzhna L, Kutanzi K, Kovalchuk O.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Feb;779:39-56. doi: 10.1016/j.mrgentox.2014.07.006. Epub 2014 Jul 29.

PMID:
25813725
42.

Altered radiation responses of breast cancer cells resistant to hormonal therapy.

Luzhna L, Lykkesfeldt AE, Kovalchuk O.

Oncotarget. 2015 Jan 30;6(3):1678-94.

43.

Development-dependent expression of DNA repair genes and epigenetic regulators in Arabidopsis plants exposed to ionizing radiation.

Sidler C, Li D, Kovalchuk O, Kovalchuk I.

Radiat Res. 2015 Feb;183(2):219-32. doi: 10.1667/RR13840.1. Epub 2015 Jan 16.

PMID:
25594540
44.

Low dose irradiation profoundly affects transcriptome and microRNAme in rat mammary gland tissues.

Luzhna L, Kovalchuk O.

Oncoscience. 2014 Nov 10;1(11):751-62. eCollection 2014.

45.

SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation.

Sidler C, Li D, Wang B, Kovalchuk I, Kovalchuk O.

Front Genet. 2014 Nov 21;5:411. doi: 10.3389/fgene.2014.00411. eCollection 2014.

46.

Age-dependent changes in DNA repair in radiation-exposed mice.

Kovalchuk IP, Golubov A, Koturbash IV, Kutanzi K, Martin OA, Kovalchuk O.

Radiat Res. 2014 Dec;182(6):683-94. doi: 10.1667/RR13697.1.

PMID:
25409128
47.

Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy.

Ruan Y, Kovalchuk A, Jayanthan A, Lun X, Nagashima Y, Kovalchuk O, Wright JR Jr, Pinto A, Kirton A, Anderson R, Narendran A.

Neuro Oncol. 2015 Jun;17(6):822-31. doi: 10.1093/neuonc/nou310. Epub 2014 Nov 12.

48.

Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways.

Lezhnina K, Kovalchuk O, Zhavoronkov AA, Korzinkin MB, Zabolotneva AA, Shegay PV, Sokov DG, Gaifullin NM, Rusakov IG, Aliper AM, Roumiantsev SA, Alekseev BY, Borisov NM, Buzdin AA.

Oncotarget. 2014 Oct 15;5(19):9022-32.

49.

Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes.

Yao Y, Robinson AM, Zucchi FC, Robbins JC, Babenko O, Kovalchuk O, Kovalchuk I, Olson DM, Metz GA.

BMC Med. 2014 Aug 7;12:121. doi: 10.1186/s12916-014-0121-6.

50.

WI-38 senescence is associated with global and site-specific hypomethylation.

Sidler C, Woycicki R, Kovalchuk I, Kovalchuk O.

Aging (Albany NY). 2014 Jul;6(7):564-74.

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