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An electroglottographical analysis-based discriminant function model differentiating multiple sclerosis patients from healthy controls.

Vavougios GD, Doskas T, Konstantopoulos K.

Neurol Sci. 2018 Feb 15. doi: 10.1007/s10072-018-3267-8. [Epub ahead of print]


Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

Pardo-Pastor C, Rubio-Moscardo F, Vogel-González M, Serra SA, Afthinos A, Mrkonjic S, Destaing O, Abenza JF, Fernández-Fernández JM, Trepat X, Albiges-Rizo C, Konstantopoulos K, Valverde MA.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1925-1930. doi: 10.1073/pnas.1718177115. Epub 2018 Feb 5.


Microtubules tune mechanotransduction through NOX2 and TRPV4 to decrease sclerostin abundance in osteocytes.

Lyons JS, Joca HC, Law RA, Williams KM, Kerr JP, Shi G, Khairallah RJ, Martin SS, Konstantopoulos K, Ward CW, Stains JP.

Sci Signal. 2017 Nov 21;10(506). pii: eaan5748. doi: 10.1126/scisignal.aan5748.


The Significance of PET/CT in the Initial Staging of Hodgkin Lymphoma: Experience Outside Clinical Trials.

Angelopoulou MK, Mosa E, Pangalis GA, Rondogianni P, Chatziioannou S, Prassopoulos V, Moschogianni M, Tsirkinidis P, Asimakopoulos JV, Konstantinou I, Tsourouflis G, Sachanas S, Yiakoumis X, Boutsikas G, Arapaki M, Gainaru G, Kyrtsonis MC, Siakantaris MP, Datseris I, Panayiotidis P, Konstantopoulos K, Vassilakopoulos TP.

Anticancer Res. 2017 Oct;37(10):5727-5736.


Protein Z (PZ) and plasminogen activator inhibitor-1 (PAI-1) plasma levels in patients with previously untreated Hodgkin lymphoma (HL).

Boutsikas G, Terpos E, Markopoulos A, Papatheodorou A, Stefanou A, Georgiou G, Galani Z, Komninaka V, Telonis V, Anagnostopoulos I, Dimitrakopoulou L, Anargyrou K, Tsionos K, Christoulas D, Gonianaki M, Giannikos T, Kokoris S, Konstantopoulos K, Meletis J, Angelopoulou MK, Travlou A, Vassilakopoulos TP.

J BUON. 2017 Jul-Aug;22(4):1022-1031.


Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness.

Stroka KM, Wong BS, Shriver M, Phillip JM, Wirtz D, Kontrogianni-Konstantopoulos A, Konstantopoulos K.

Oncotarget. 2016 Aug 1;8(33):54004-54020. doi: 10.18632/oncotarget.10997. eCollection 2017 Aug 15.


E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid.

Shea DJ, Li YW, Stebe KJ, Konstantopoulos K.

FASEB J. 2017 Nov;31(11):5078-5086. doi: 10.1096/fj.201700331R. Epub 2017 Aug 1.


Hypercalcemia remains an adverse prognostic factor for newly diagnosed multiple myeloma patients in the era of novel antimyeloma therapies.

Zagouri F, Kastritis E, Zomas A, Terpos E, Katodritou E, Symeonidis A, Delimpasi S, Pouli A, Vassilakopoulos TP, Michalis E, Giannouli S, Kartasis Z, Christoforidou A, Kokoviadou K, Hatzimichael E, Gika D, Megalakaki C, Papaioannou M, Kyrtsonis MC, Konstantopoulos K, Dimopoulos MA; Greek Myeloma Study Group.

Eur J Haematol. 2017 Nov;99(5):409-414. doi: 10.1111/ejh.12923. Epub 2017 Sep 26.


Bone metabolism markers and angiogenic cytokines as regulators of human hematopoietic stem cell mobilization.

Tsirkinidis P, Terpos E, Boutsikas G, Papatheodorou A, Anargyrou K, Lalou E, Dimitrakopoulou A, Kalpadakis C, Konstantopoulos K, Siakantaris M, Panayiotidis P, Pangalis G, Kyrtsonis MC, Vassilakopoulos T, Angelopoulou MK.

J Bone Miner Metab. 2017 Jun 28. doi: 10.1007/s00774-017-0853-4. [Epub ahead of print]


Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

Sengupta S, Nagalingam A, Muniraj N, Bonner MY, Mistriotis P, Afthinos A, Kuppusamy P, Lanoue D, Cho S, Korangath P, Shriver M, Begum A, Merino VF, Huang CY, Arbiser JL, Matsui W, Győrffy B, Konstantopoulos K, Sukumar S, Marignani PA, Saxena NK, Sharma D.

Oncogene. 2017 Oct 12;36(41):5709-5721. doi: 10.1038/onc.2017.164. Epub 2017 Jun 5.


Thioredoxin-1, chemokine (C-X-C motif) ligand-9 and interferon-γ expression in the neoplastic cells and macrophages of Hodgkin lymphoma: clinicopathologic correlations and potential prognostic implications.

P Vassilakopoulos T, Levidou G, Milionis V, Hartmann S, Lakiotaki E, Sepsa A, Thymara I, Ntailiani P, Spanou K, K Angelopoulou M, P Siakantaris M, Moschogiannis M, A Pangalis G, Panayiotidis P, Konstantopoulos K, Patsouris E, Hansmann ML, Korkolopoulou P.

Leuk Lymphoma. 2017 Sep;58(9):1-13. doi: 10.1080/10428194.2017.1289520. Epub 2017 Jun 2.


Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN.

Christou YP, Tanteles GA, Kkolou E, Ormiston A, Konstantopoulos K, Beconi M, Marshall RD, Plotkin H, Kleopa KA.

Case Rep Neurol Med. 2017;2017:3247034. doi: 10.1155/2017/3247034. Epub 2017 Apr 16.


A quantitative method for the assessment of dysarthrophonia in myasthenia gravis.

Konstantopoulos K, Christou YP, Vogazianos P, Zamba-Papanicolaou E, Kleopa KA.

J Neurol Sci. 2017 Jun 15;377:42-46. doi: 10.1016/j.jns.2017.03.045. Epub 2017 Mar 31.


Overexpression of VLA-4 in glial-restricted precursors enhances their endothelial docking and induces diapedesis in a mouse stroke model.

Jablonska A, Shea DJ, Cao S, Bulte JW, Janowski M, Konstantopoulos K, Walczak P.

J Cereb Blood Flow Metab. 2017 Jan 1:271678X17703888. doi: 10.1177/0271678X17703888. [Epub ahead of print]


Racial variation and cancer: a historical approach.

Karamanou M, Tekiner H, Papaioannou TG, Konstantopoulos K, Androutsos G.

J BUON. 2016 Nov-Dec;21(6):1568-1570.


Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease.

Armenis I, Kalotychou V, Tzanetea R, Kollia P, Kontogeorgiou Z, Anastasopoulou D, Mantzourani M, Samarkos M, Pantos K, Konstantopoulos K, Rombos I.

Data Brief. 2016 Nov 28;10:192-197. eCollection 2017 Feb.


Recurrent acute myopericarditis without effusion during ATRA induction and ATO salvage of APL: a variant form of the differentiation syndrome?

Vassilakopoulos TP, Asimakopoulos JV, Plata E, Kelepesis G, Petevi K, Koutsi C, Papageorgiou L, Tsaftaridis P, Angelopoulou MK, Konstantopoulos K, Meletis J.

Leuk Lymphoma. 2017 Jul;58(7):1743-1746. doi: 10.1080/10428194.2016.1253838. Epub 2016 Dec 6. No abstract available.


Cancer cell motility: lessons from migration in confined spaces.

Paul CD, Mistriotis P, Konstantopoulos K.

Nat Rev Cancer. 2017 Feb;17(2):131-140. doi: 10.1038/nrc.2016.123. Epub 2016 Dec 2. Review.


Prognostic value of T786C and G894T eNOS polymorphisms in sickle cell disease.

Armenis I, Kalotychou V, Tzanetea R, Kollia P, Kontogeorgiou Z, Anastasopoulou D, Mantzourani M, Samarkos M, Pantos K, Konstantopoulos K, Rombos I.

Nitric Oxide. 2017 Jan 30;62:17-23. doi: 10.1016/j.niox.2016.11.002. Epub 2016 Nov 18.


Evaluation of the Revised International Staging System in an independent cohort of unselected patients with multiple myeloma.

Kastritis E, Terpos E, Roussou M, Gavriatopoulou M, Migkou M, Eleutherakis-Papaiakovou E, Fotiou D, Ziogas D, Panagiotidis I, Kafantari E, Giannouli S, Zomas A, Konstantopoulos K, Dimopoulos MA.

Haematologica. 2017 Mar;102(3):593-599. doi: 10.3324/haematol.2016.145078. Epub 2016 Oct 27.


Time-lapse lens-free imaging of cell migration in diverse physical microenvironments.

Mathieu E, Paul CD, Stahl R, Vanmeerbeeck G, Reumers V, Liu C, Konstantopoulos K, Lagae L.

Lab Chip. 2016 Aug 16;16(17):3304-16. doi: 10.1039/c6lc00860g.


Engineered Models of Confined Cell Migration.

Paul CD, Hung WC, Wirtz D, Konstantopoulos K.

Annu Rev Biomed Eng. 2016 Jul 11;18:159-80. doi: 10.1146/annurev-bioeng-071114-040654. Review.


Class 3 semaphorins induce F-actin reorganization in human dendritic cells: Role in cell migration.

Curreli S, Wong BS, Latinovic O, Konstantopoulos K, Stamatos NM.

J Leukoc Biol. 2016 Dec;100(6):1323-1334. Epub 2016 Jul 12.


Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit.

Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, Kontrogianni-Konstantopoulos A.

Oncotarget. 2016 Jul 19;7(29):45414-45428. doi: 10.18632/oncotarget.9985.


Response to 'PET after response to R-CHOP in primary mediastinal large B-cell lymphoma'.

Vassilakopoulos TP, Papageorgiou S, Pangalis GA, Chatziioannou S, Angelopoulou MK, Panayiotidis P, Konstantopoulos K, Rondogianni P.

Leukemia. 2016 Aug;30(8):1800-1. doi: 10.1038/leu.2016.109. Epub 2016 Jun 3. No abstract available.


Endocannabinoid System: A Promising Therapeutic Target for the Treatment of Haematological Malignancies?

Giaginis C, Lakiotaki E, Korkolopoulou P, Konstantopoulos K, Patsouris E, Theocharis S.

Curr Med Chem. 2016;23(22):2350-62. Review.


Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.

Hung WC, Yang JR, Yankaskas CL, Wong BS, Wu PH, Pardo-Pastor C, Serra SA, Chiang MJ, Gu Z, Wirtz D, Valverde MA, Yang JT, Zhang J, Konstantopoulos K.

Cell Rep. 2016 May 17;15(7):1430-1441. doi: 10.1016/j.celrep.2016.04.035. Epub 2016 May 5.


Prognostic Implication of the Absolute Lymphocyte to Absolute Monocyte Count Ratio in Patients With Classical Hodgkin Lymphoma Treated With Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine or Equivalent Regimens.

Vassilakopoulos TP, Dimopoulou MN, Angelopoulou MK, Petevi K, Pangalis GA, Moschogiannis M, Dimou M, Boutsikas G, Kanellopoulos A, Gainaru G, Plata E, Flevari P, Koutsi K, Papageorgiou L, Telonis V, Tsaftaridis P, Sachanas S, Yiakoumis X, Tsirkinidis P, Viniou NA, Siakantaris MP, Variami E, Kyrtsonis MC, Meletis J, Panayiotidis P, Konstantopoulos K.

Oncologist. 2016 Mar;21(3):343-53. doi: 10.1634/theoncologist.2015-0251. Epub 2016 Feb 26.


Interplay of the physical microenvironment, contact guidance, and intracellular signaling in cell decision making.

Paul CD, Shea DJ, Mahoney MR, Chai A, Laney V, Hung WC, Konstantopoulos K.

FASEB J. 2016 Jun;30(6):2161-70. doi: 10.1096/fj.201500199R. Epub 2016 Feb 22.


Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome.

Lakiotaki E, Levidou G, Angelopoulou MK, Adamopoulos C, Pangalis G, Rassidakis G, Vassilakopoulos T, Gainaru G, Flevari P, Sachanas S, Saetta AA, Sepsa A, Moschogiannis M, Kalpadakis C, Tsesmetzis N, Milionis V, Chatziandreou I, Thymara I, Panayiotidis P, Dimopoulou M, Plata E, Konstantopoulos K, Patsouris E, Piperi C, Korkolopoulou P.

Sci Rep. 2016 Feb 19;6:21252. doi: 10.1038/srep21252.


Normative Data of the Montreal Cognitive Assessment in the Greek Population and Parkinsonian Dementia.

Konstantopoulos K, Vogazianos P, Doskas T.

Arch Clin Neuropsychol. 2016 May;31(3):246-53. doi: 10.1093/arclin/acw002. Epub 2016 Feb 17.


The Role of Bronchoscopic Findings and Bronchoalveolar Lavage Fluid Cytology in Early Diagnosis of Ventilator-Associated Pneumonia.

Vernikos P, Kampolis CF, Konstantopoulos K, Armaganidis A, Karakitsos P.

Respir Care. 2016 May;61(5):658-67. doi: 10.4187/respcare.04265. Epub 2016 Feb 2.


Pyrexia of unknown origin: the role of blood film microscopy.

Konstantopoulos K.

Postgrad Med J. 2016 May;92(1087):301. doi: 10.1136/postgradmedj-2015-133925. Epub 2016 Jan 21. No abstract available.


Local 3D matrix confinement determines division axis through cell shape.

He L, Chen W, Wu PH, Jimenez A, Wong BS, San A, Konstantopoulos K, Wirtz D.

Oncotarget. 2016 Feb 9;7(6):6994-7011. doi: 10.18632/oncotarget.5848.


HER2 missense mutations have distinct effects on oncogenic signaling and migration.

Zabransky DJ, Yankaskas CL, Cochran RL, Wong HY, Croessmann S, Chu D, Kavuri SM, Red Brewer M, Rosen DM, Dalton WB, Cimino-Mathews A, Cravero K, Button B, Kyker-Snowman K, Cidado J, Erlanger B, Parsons HA, Manto KM, Bose R, Lauring J, Arteaga CL, Konstantopoulos K, Park BH.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6205-14. doi: 10.1073/pnas.1516853112. Epub 2015 Oct 27.


Lower Levels of Vitamin D Among Bangladeshi Immigrants with Diabetes in Greece Compared to Indigenous Greek Patients with Diabetes.

Papadakis G, Zambelis T, Villiotou V, Dogkas N, Pappas A, Keramidas I, Kakava K, Michalopoulou M, Rosenberg T, Konstantopoulos K, Chatzipanagiotou S.

In Vivo. 2015 Sep-Oct;29(5):541-5.


Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow.

Shea DJ, Wirtz D, Stebe KJ, Konstantopoulos K.

Oncotarget. 2015 Sep 22;6(28):24842-55. doi: 10.18632/oncotarget.4704.


By suppressing the expression of anterior pharynx-defective-1α and -1β and inhibiting the aggregation of β-amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice.

Yu X, Guan PP, Guo JW, Wang Y, Cao LL, Xu GB, Konstantopoulos K, Wang ZY, Wang P.

FASEB J. 2015 Dec;29(12):5044-58. doi: 10.1096/fj.15-275578. Epub 2015 Aug 20.


Significance of the detection of paroxysmal nocturnal hemoglobinuria clones in patients with multiple myeloma undergoing autologous stem cell transplantation.

Chatziantoniou V, Alexia S, Konstantopoulos K, Repousis P, Megalakaki A, Kotsopoulou M, Kylidou P, Vassilakopoulos T, Angelopoulou MK.

Hematol Oncol Stem Cell Ther. 2015 Dec;8(4):150-9. doi: 10.1016/j.hemonc.2015.06.008. Epub 2015 Jul 9.


The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage.

Guan PP, Guo JW, Yu X, Wang Y, Wang T, Konstantopoulos K, Wang ZY, Wang P.

Sci Rep. 2015 May 20;5:10412. doi: 10.1038/srep10412.


PET/CT in primary mediastinal large B-cell lymphoma responding to rituximab-CHOP: An analysis of 106 patients regarding prognostic significance and implications for subsequent radiotherapy.

Vassilakopoulos TP, Pangalis GA, Chatziioannou S, Papageorgiou S, Angelopoulou MK, Galani Z, Kourti G, Prassopoulos V, Leonidopoulou T, Terpos E, Dimopoulou MN, Sachanas S, Kalpadakis C, Konstantinidou P, Boutsis D, Stefanoudaki E, Kyriazopoulou L, Siakantaris MP, Kyrtsonis MC, Variami E, Kotsianidis I, Symeonidis A, Michali E, Katodritou E, Kokkini G, Tsatalas C, Papadaki H, Dimopoulos MA, Sotiropoulos V, Pappa V, Karmiris T, Meletis J, Apostolidis J, Datseris I, Panayiotidis P, Konstantopoulos K, Roussou P, Rondogianni P.

Leukemia. 2016 Jan;30(1):238-42. doi: 10.1038/leu.2015.120. Epub 2015 May 14. No abstract available.


By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization.

Guan PP, Yu X, Guo JJ, Wang Y, Wang T, Li JY, Konstantopoulos K, Wang ZY, Wang P.

Oncotarget. 2015 Apr 20;6(11):9140-59.


Epidemiological and clinical study of diabetes in immigrants from Bangladesh in Athens versus Greek patients.

Papadakis G, Zampelis T, Michalopoulou M, Konstantopoulos K, Rosenberg T, Chatzipanagiotou S.

In Vivo. 2015 Mar-Apr;29(2):223-7.


Prayer Marks in Immigrants from Bangladesh with Diabetes Who Live in Greece.

Papadakis G, Zampelis T, Michalopoulou M, Konstantopoulos K, Rosenberg T, Chatzipanagiotou S.

J Immigr Minor Health. 2016 Feb;18(1):274-6. doi: 10.1007/s10903-015-0184-2.


Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics.

Cheung LS, Shea DJ, Nicholes N, Date A, Ostermeier M, Konstantopoulos K.

Sci Rep. 2015 Feb 4;5:8247. doi: 10.1038/srep08247.


Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.

Wang P, Chen SH, Hung WC, Paul C, Zhu F, Guan PP, Huso DL, Kontrogianni-Konstantopoulos A, Konstantopoulos K.

Oncogene. 2015 Aug 27;34(35):4558-69. doi: 10.1038/onc.2014.397. Epub 2014 Dec 1.


Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.

Shriver M, Stroka KM, Vitolo MI, Martin S, Huso DL, Konstantopoulos K, Kontrogianni-Konstantopoulos A.

Oncogene. 2015 Aug 6;34(32):4248-59. doi: 10.1038/onc.2014.358. Epub 2014 Nov 10.


Gastric involvement in patients with primary mediastinal large B-cell lymphoma.

Papageorgiou SG, Sachanas S, Pangalis GA, Tsopra O, Levidou G, Foukas P, Rondogianni P, Sotiropoulos V, Ioannidou HD, Gassiamis A, Iliakis T, Korkolopoulou P, Angelopoulou MK, Pappa V, Konstantopoulos K, Vassilakopoulos TP.

Anticancer Res. 2014 Nov;34(11):6717-23.


Bioengineering paradigms for cell migration in confined microenvironments.

Stroka KM, Gu Z, Sun SX, Konstantopoulos K.

Curr Opin Cell Biol. 2014 Oct;30:41-50. doi: 10.1016/ Epub 2014 Jun 26. Review.


A normative study of the Children's Color Trails Test (CCTT) in the Cypriot population.

Konstantopoulos K, Vogazianos P, Thodi C, Nikopoulou-Smyrni P.

Child Neuropsychol. 2015;21(6):751-8. doi: 10.1080/09297049.2014.924491. Epub 2014 Jun 5.


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