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Items: 42


Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium.

Kalinowski A, Galen BT, Ueki IF, Sun Y, Mulenos A, Osafo-Addo A, Clark B, Joerns J, Liu W, Nadel JA, Dela Cruz CS, Koff JL.

Mucosal Immunol. 2018 Feb 7. doi: 10.1038/mi.2017.120. [Epub ahead of print]


Peritransplantation Red Blood Cell Transfusion Is Associated with Increased Risk of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Hosoba S, Waller EK, Shenvi N, Graiser M, Easley KA, Al-Kadhimi Z, Andoh A, Antun AG, Barclay S, Josephson CD, Koff JL, Khoury HJ, Langston AA, Zimring JC, Roback JD, Giver CR.

Biol Blood Marrow Transplant. 2018 Jan 4. pii: S1083-8791(18)30003-X. doi: 10.1016/j.bbmt.2018.01.003. [Epub ahead of print]


Characterizing Autoimmune Disease-associated Diffuse Large B-cell Lymphoma in a SEER-Medicare Cohort.

Koff JL, Rai A, Flowers CR.

Clin Lymphoma Myeloma Leuk. 2018 Feb;18(2):e115-e121. doi: 10.1016/j.clml.2017.11.009. Epub 2017 Dec 2.


Effective management strategies for patients with marginal zone lymphoma.

Rosand CB, Valla K, Flowers CR, Koff JL.

Future Oncol. 2017 Dec 20. doi: 10.2217/fon-2017-0480. [Epub ahead of print]


Exploring the potential cost-effectiveness of precision medicine treatment strategies for diffuse large B-cell lymphoma.

Chen Q, Staton AD, Ayer T, Goldstein DA, Koff JL, Flowers CR.

Leuk Lymphoma. 2017 Oct 25:1-10. doi: 10.1080/10428194.2017.1390230. [Epub ahead of print]


Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS.

Cell. 2017 Oct 5;171(2):481-494.e15. doi: 10.1016/j.cell.2017.09.027.


Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages.

Di Pietro C, Zhang PX, O'Rourke TK, Murray TS, Wang L, Britto CJ, Koff JL, Krause DS, Egan ME, Bruscia EM.

Sci Rep. 2017 Sep 7;7(1):10882. doi: 10.1038/s41598-017-11012-7.


Surveillance imaging in mantle cell lymphoma in first remission lacks clinical utility.

Guidot DM, Switchenko JM, Nastoupil LJ, Koff JL, Blum KA, Maly J, Flowers CR, Cohen JB.

Leuk Lymphoma. 2018 Apr;59(4):888-895. doi: 10.1080/10428194.2017.1361032. Epub 2017 Aug 10.


Correction: DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia.

Ye Y, Lin P, Zhang W, Tan S, Zhou X, Li R, Pu Q, Koff JL, Dhasarathy A, Ma F, Deng X, Jiang J, Wu M.

J Immunol. 2017 Aug 1;199(3):1207. doi: 10.4049/jimmunol.1700711. No abstract available.


Response to Comment on "DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia".

Ye Y, Lin P, Zhang W, Tan S, Zhou X, Li R, Pu Q, Koff JL, Dhasarathy A, Ma F, Deng X, Jiang J, Wu M.

J Immunol. 2017 Jul 15;199(2):381-382. doi: 10.4049/jimmunol.1700676. No abstract available.


Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice.

Wong CK, Smith CA, Sakamoto K, Kaminski N, Koff JL, Goldstein DR.

J Immunol. 2017 Aug 1;199(3):1060-1068. doi: 10.4049/jimmunol.1700397. Epub 2017 Jun 23.


Cystic Fibrosis Transmembrane Regulator Modulators: Implications for the Management of Depression and Anxiety in Cystic Fibrosis.

Talwalkar JS, Koff JL, Lee HB, Britto CJ, Mulenos AM, Georgiopoulos AM.

Psychosomatics. 2017 Jul - Aug;58(4):343-354. doi: 10.1016/j.psym.2017.04.001. Epub 2017 Apr 5. Review.


Prognostic modeling in diffuse large B-cell lymphoma in the era of immunochemotherapy: Where do we go from here?

Koff JL, Flowers CR.

Cancer. 2017 Sep 1;123(17):3222-3225. doi: 10.1002/cncr.30740. Epub 2017 May 2. No abstract available.


Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.

Guo X, Koff JL, Moffitt AB, Cinar M, Ramachandiran S, Chen Z, Switchenko JM, Mosunjac M, Neill SG, Mann KP, Bagirov M, Du Y, Natkunam Y, Khoury HJ, Rossi MR, Harris W, Flowers CR, Lossos IS, Boise LH, Dave SS, Kowalski J, Bernal-Mizrachi L.

Oncogene. 2017 Jul 20;36(29):4224-4232. doi: 10.1038/onc.2017.90. Epub 2017 Apr 3.


DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia.

Ye Y, Lin P, Zhang W, Tan S, Zhou X, Li R, Pu Q, Koff JL, Dhasarathy A, Ma F, Deng X, Jiang J, Wu M.

J Immunol. 2017 Apr 1;198(7):2844-2853. doi: 10.4049/jimmunol.1601001. Epub 2017 Feb 15. Erratum in: J Immunol. 2017 Aug 1;199(3):1207.


Relations Between Residential Proximity to EPA-Designated Toxic Release Sites and Diffuse Large B-Cell Lymphoma Incidence.

Bulka C, Nastoupil LJ, Koff JL, Bernal-Mizrachi L, Ward KC, Williams JN, Bayakly AR, Switchenko JM, Waller LA, Flowers CR.

South Med J. 2016 Oct;109(10):606-614.


Integrating understanding of epidemiology and genomics in B-cell non-Hodgkin lymphoma as a pathway to novel management strategies.

Glass S, Phan A, Williams JN, Flowers CR, Koff JL.

Discov Med. 2016 Mar;21(115):181-8. Review.


B cells gone rogue: the intersection of diffuse large B cell lymphoma and autoimmune disease.

Koff JL, Flowers CR.

Expert Rev Hematol. 2016 Jun;9(6):553-61. doi: 10.1080/17474086.2016.1180972. Epub 2016 May 13. Review.


Resolving uncertainty in the spatial relationships between passive benzene exposure and risk of non-Hodgkin lymphoma.

Switchenko JM, Bulka C, Ward K, Koff JL, Bayakly AR, Ryan PB, Waller LA, Flowers CR.

Cancer Epidemiol. 2016 Apr;41:139-51. doi: 10.1016/j.canep.2016.01.008. Epub 2016 Mar 2.


Emerging treatments in Castleman disease - a critical appraisal of siltuximab.

Koff JL, Lonial S.

Biologics. 2016 Jan 25;10:9-15. doi: 10.2147/BTT.S60523. eCollection 2016. Review.


Cystic Fibrosis.

Koff JL.

Clin Chest Med. 2016 Mar;37(1):xv-xvi. doi: 10.1016/j.ccm.2015.12.001. Epub 2015 Dec 24. No abstract available.


Population-specific prognostic models are needed to stratify outcomes for African-Americans with diffuse large B-cell lymphoma.

Chen Q, Ayer T, Nastoupil LJ, Koff JL, Staton AD, Chhatwal J, Flowers CR.

Leuk Lymphoma. 2016;57(4):842-51. doi: 10.3109/10428194.2015.1083098. Epub 2015 Dec 15.


Next-generation prognostic assessment for diffuse large B-cell lymphoma.

Staton AD, Koff JL, Chen Q, Ayer T, Flowers CR.

Future Oncol. 2015;11(17):2443-57. doi: 10.2217/fon.15.144. Epub 2015 Aug 20. Review.


A phase II study of bortezomib added to rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone in patients with previously untreated indolent non-Hodgkin's lymphoma.

Cohen JB, Switchenko JM, Koff JL, Sinha R, Kaufman JL, Khoury HJ, Bumpers N, Colbert A, Hutchison-Rzepka A, Nastoupil LJ, Heffner LT, Langston AA, Lechowicz MJ, Lonial S, Flowers CR.

Br J Haematol. 2015 Nov;171(4):539-46. doi: 10.1111/bjh.13637. Epub 2015 Aug 7.


Reply to Treatment decisions and outcome in very elderly patients with diffuse large B-cell lymphoma.

Williams JN, Koff JL, Flowers CR.

Cancer. 2015 Oct 15;121(20):3748. doi: 10.1002/cncr.29508. Epub 2015 Jun 25. No abstract available.


To Each Its Own: Linking the Biology and Epidemiology of NHL Subtypes.

Koff JL, Chihara D, Phan A, Nastoupil LJ, Williams JN, Flowers CR.

Curr Hematol Malig Rep. 2015 Sep;10(3):244-55. doi: 10.1007/s11899-015-0267-0. Review.


New insights into the epidemiology of non-Hodgkin lymphoma and implications for therapy.

Chihara D, Nastoupil LJ, Williams JN, Lee P, Koff JL, Flowers CR.

Expert Rev Anticancer Ther. 2015 May;15(5):531-44. doi: 10.1586/14737140.2015.1023712. Epub 2015 Apr 11. Review.


Disease characteristics, patterns of care, and survival in very elderly patients with diffuse large B-cell lymphoma.

Williams JN, Rai A, Lipscomb J, Koff JL, Nastoupil LJ, Flowers CR.

Cancer. 2015 Jun 1;121(11):1800-8. doi: 10.1002/cncr.29290. Epub 2015 Feb 11.


Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation.

Zhang PX, Cheng J, Zou S, D'Souza AD, Koff JL, Lu J, Lee PJ, Krause DS, Egan ME, Bruscia EM.

Nat Commun. 2015 Feb 10;6:6221. doi: 10.1038/ncomms7221.


A time to kill: targeting apoptosis in cancer.

Koff JL, Ramachandiran S, Bernal-Mizrachi L.

Int J Mol Sci. 2015 Jan 28;16(2):2942-55. doi: 10.3390/ijms16022942. Review.


Novel therapies in mantle cell lymphoma: a pathway to chemotherapy-free strategies.

Nastoupil LJ, Koff JL, Flowers CR.

Oncology (Williston Park). 2013 Oct;27 Suppl 2:8-12. Review.


Comparison of the effectiveness of frontline chemoimmunotherapy regimens for follicular lymphoma used in the United States.

Nastoupil LJ, Sinha R, Byrtek M, Ziemiecki R, Taylor M, Friedberg JW, Koff JL, Link BK, Cerhan JR, Dawson KL, Flowers CR.

Leuk Lymphoma. 2015 May;56(5):1295-302. doi: 10.3109/10428194.2014.953144. Epub 2014 Nov 5.


Evaluating cell-of-origin subtype methods for predicting diffuse large B-cell lymphoma survival: a meta-analysis of gene expression profiling and immunohistochemistry algorithms.

Read JA, Koff JL, Nastoupil LJ, Williams JN, Cohen JB, Flowers CR.

Clin Lymphoma Myeloma Leuk. 2014 Dec;14(6):460-467.e2. doi: 10.1016/j.clml.2014.05.002. Epub 2014 Jun 12.


EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production.

Kalinowski A, Ueki I, Min-Oo G, Ballon-Landa E, Knoff D, Galen B, Lanier LL, Nadel JA, Koff JL.

Am J Physiol Lung Cell Mol Physiol. 2014 Jul 15;307(2):L186-96. doi: 10.1152/ajplung.00368.2013. Epub 2014 May 16.


Intensive chemotherapy and consolidation with high dose therapy and autologous stem cell transplant in patients with mantle cell lymphoma.

Nastoupil LJ, Shenoy PJ, Ambinder A, Koff JL, Nooka AK, Waller EK, Langston A, Seward M, Kaufman JL, Bernal-Mizrachi L, King N, Lechowicz MJ, Lonial S, Sinha R, Flowers CR.

Leuk Lymphoma. 2015 Feb;56(2):383-9. doi: 10.3109/10428194.2014.921296. Epub 2014 Jul 17.


Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium.

Ueki IF, Min-Oo G, Kalinowski A, Ballon-Landa E, Lanier LL, Nadel JA, Koff JL.

J Exp Med. 2013 Sep 23;210(10):1929-36. doi: 10.1084/jem.20121401. Epub 2013 Sep 2.


Rhinovirus and other respiratory viruses exert different effects on lung allograft function that are not mediated through acute rejection.

Sayah DM, Koff JL, Leard LE, Hays SR, Golden JA, Singer JP.

Clin Transplant. 2013 Jan-Feb;27(1):E64-71. doi: 10.1111/ctr.12054. Epub 2012 Dec 30.


Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis.

Zhou Y, Lee JY, Lee CM, Cho WK, Kang MJ, Koff JL, Yoon PO, Chae J, Park HO, Elias JA, Lee CG.

J Biol Chem. 2012 Dec 7;287(50):41991-2000. doi: 10.1074/jbc.M112.356824. Epub 2012 Oct 19.


The impact of pretransplant mechanical ventilation on short- and long-term survival after lung transplantation.

Singer JP, Blanc PD, Hoopes C, Golden JA, Koff JL, Leard LE, Cheng S, Chen H.

Am J Transplant. 2011 Oct;11(10):2197-204. doi: 10.1111/j.1600-6143.2011.03684.x. Epub 2011 Aug 10.


Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium.

Koff JL, Shao MX, Ueki IF, Nadel JA.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1068-75. doi: 10.1152/ajplung.00025.2008. Epub 2008 Mar 28.


Regulation of interleukin-8 via an airway epithelial signaling cascade.

Nakanaga T, Nadel JA, Ueki IF, Koff JL, Shao MX.

Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1289-96. Epub 2007 Jan 12.


Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.

Koff JL, Shao MX, Kim S, Ueki IF, Nadel JA.

J Immunol. 2006 Dec 15;177(12):8693-700.

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