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Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Nagy-Szakal D, Williams BL, Mishra N, Che X, Lee B, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Ramanan D, Jain K, Eddy ML, Hornig M, Lipkin WI.

Microbiome. 2017 Apr 26;5(1):44. doi: 10.1186/s40168-017-0261-y.


Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.

Unger ER, Lin JS, Tian H, Natelson BH, Lange G, Vu D, Blate M, Klimas NG, Balbin EG, Bateman L, Allen A, Lapp CW, Springs W, Kogelnik AM, Phan CC, Danver J, Podell RN, Fitzpatrick T, Peterson DL, Gottschalk CG, Rajeevan MS; MCAM Study Group.

Am J Epidemiol. 2017 Apr 15;185(8):617-626. doi: 10.1093/aje/kwx029.


Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology.

Halpin P, Williams MV, Klimas NG, Fletcher MA, Barnes Z, Ariza ME.

J Med Virol. 2017 Sep;89(9):1636-1645. doi: 10.1002/jmv.24810. Epub 2017 Apr 26.


Gastric Enterovirus Infection: A Possible Causative Etiology of Gastroparesis.

Barkin JA, Czul F, Barkin JS, Klimas NG, Rey IR, Moshiree B.

Dig Dis Sci. 2016 Aug;61(8):2344-50. doi: 10.1007/s10620-016-4227-x. Epub 2016 Jun 25.


Tracking post-infectious fatigue in clinic using routine Lab tests.

Harvey JM, Broderick G, Bowie A, Barnes ZM, Katz BZ, O'Gorman MRG, Vernon SD, Fletcher MA, Klimas NG, Taylor R.

BMC Pediatr. 2016 Apr 26;16:54. doi: 10.1186/s12887-016-0596-8.


Illness progression in chronic fatigue syndrome: a shifting immune baseline.

Russell L, Broderick G, Taylor R, Fernandes H, Harvey J, Barnes Z, Smylie A, Collado F, Balbin EG, Katz BZ, Klimas NG, Fletcher MA.

BMC Immunol. 2016 Mar 10;17:3. doi: 10.1186/s12865-016-0142-3.


Achieving Remission in Gulf War Illness: A Simulation-Based Approach to Treatment Design.

Craddock TJ, Del Rosario RR, Rice M, Zysman JP, Fletcher MA, Klimas NG, Broderick G.

PLoS One. 2015 Jul 20;10(7):e0132774. doi: 10.1371/journal.pone.0132774. eCollection 2015.


Perceived Fatigue Interference and Depressed Mood: Comparison of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients with Fatigued Breast Cancer Survivors.

Hall DL, Antoni MH, Lattie EG, Jutagir DR, Czaja SJ, Perdomo D, Lechner SC, Stagl JM, Bouchard LC, Gudenkauf LM, Traeger L, Fletcher M, Klimas NG.

Fatigue. 2015;3(3):142-155.


Using gene expression signatures to identify novel treatment strategies in gulf war illness.

Craddock TJ, Harvey JM, Nathanson L, Barnes ZM, Klimas NG, Fletcher MA, Broderick G.

BMC Med Genomics. 2015 Jul 9;8:36. doi: 10.1186/s12920-015-0111-3.


Distinct plasma immune signatures in ME/CFS are present early in the course of illness.

Hornig M, Montoya JG, Klimas NG, Levine S, Felsenstein D, Bateman L, Peterson DL, Gottschalk CG, Schultz AF, Che X, Eddy ML, Komaroff AL, Lipkin WI.

Sci Adv. 2015 Feb;1(1). pii: e1400121.


Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies?

Vashishtha S, Broderick G, Craddock TJ, Fletcher MA, Klimas NG.

PLoS One. 2015 May 18;10(5):e0127364. doi: 10.1371/journal.pone.0127364. eCollection 2015.


No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank.

Irlbeck DM, Vernon SD, McCleary KK, Bateman L, Klimas NG, Lapp CW, Peterson DL, Brown JR, Remlinger KS, Wilfret DA, Gerondelis P.

BMC Res Notes. 2014 Aug 4;7:461. doi: 10.1186/1756-0500-7-461.


Stress management skills, cortisol awakening response, and post-exertional malaise in Chronic Fatigue Syndrome.

Hall DL, Lattie EG, Antoni MH, Fletcher MA, Czaja S, Perdomo D, Klimas NG.

Psychoneuroendocrinology. 2014 Nov;49:26-31. doi: 10.1016/j.psyneuen.2014.06.021. Epub 2014 Jul 6.


A role for homeostatic drive in the perpetuation of complex chronic illness: Gulf War Illness and chronic fatigue syndrome.

Craddock TJ, Fritsch P, Rice MA Jr, del Rosario RM, Miller DB, Fletcher MA, Klimas NG, Broderick G.

PLoS One. 2014 Jan 8;9(1):e84839. doi: 10.1371/journal.pone.0084839. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e94161. PLoS One. 2014;9(6):e100355.


Psychoneuroimmunology and natural killer cells: the chromium release whole blood assay.

Fletcher MA, Barnes Z, Broderick G, Klimas NG.

Methods Mol Biol. 2012;934:313-24. doi: 10.1007/978-1-62703-071-7_16.


Exploring the diagnostic potential of immune biomarker coexpression in Gulf War Illness.

Broderick G, Fletcher MA, Gallagher M, Barnes Z, Vernon SD, Klimas NG.

Methods Mol Biol. 2012;934:145-64. doi: 10.1007/978-1-62703-071-7_8.


Biomarkers for chronic fatigue.

Klimas NG, Broderick G, Fletcher MA.

Brain Behav Immun. 2012 Nov;26(8):1202-10. doi: 10.1016/j.bbi.2012.06.006. Epub 2012 Jun 23. Review.


Myalgic encephalomyelitis: International Consensus Criteria.

Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T, Staines D, Powles AC, Speight N, Vallings R, Bateman L, Baumgarten-Austrheim B, Bell DS, Carlo-Stella N, Chia J, Darragh A, Jo D, Lewis D, Light AR, Marshall-Gradisbik S, Mena I, Mikovits JA, Miwa K, Murovska M, Pall ML, Stevens S.

J Intern Med. 2011 Oct;270(4):327-38. doi: 10.1111/j.1365-2796.2011.02428.x. Epub 2011 Aug 22. Review. Erratum in: J Intern Med. 2017 Oct;282(4):353.


Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis.

Brenu EW, van Driel ML, Staines DR, Ashton KJ, Ramos SB, Keane J, Klimas NG, Marshall-Gradisnik SM.

J Transl Med. 2011 May 28;9:81. doi: 10.1186/1479-5876-9-81.


Plasma neuropeptide Y: a biomarker for symptom severity in chronic fatigue syndrome.

Fletcher MA, Rosenthal M, Antoni M, Ironson G, Zeng XR, Barnes Z, Harvey JM, Hurwitz B, Levis S, Broderick G, Klimas NG.

Behav Brain Funct. 2010 Dec 29;6:76. doi: 10.1186/1744-9081-6-76.


Biomarkers in chronic fatigue syndrome: evaluation of natural killer cell function and dipeptidyl peptidase IV/CD26.

Fletcher MA, Zeng XR, Maher K, Levis S, Hurwitz B, Antoni M, Broderick G, Klimas NG.

PLoS One. 2010 May 25;5(5):e10817. doi: 10.1371/journal.pone.0010817.


Plasma cytokines in women with chronic fatigue syndrome.

Fletcher MA, Zeng XR, Barnes Z, Levis S, Klimas NG.

J Transl Med. 2009 Nov 12;7:96. doi: 10.1186/1479-5876-7-96.


Chronic fatigue syndrome: illness severity, sedentary lifestyle, blood volume and evidence of diminished cardiac function.

Hurwitz BE, Coryell VT, Parker M, Martin P, Laperriere A, Klimas NG, Sfakianakis GN, Bilsker MS.

Clin Sci (Lond). 2009 Oct 19;118(2):125-35. doi: 10.1042/CS20090055.


Impaired immune function in Gulf War Illness.

Whistler T, Fletcher MA, Lonergan W, Zeng XR, Lin JM, Laperriere A, Vernon SD, Klimas NG.

BMC Med Genomics. 2009 Mar 5;2:12. doi: 10.1186/1755-8794-2-12.


Psychological distress, killer lymphocytes and disease severity in HIV/AIDS.

Greeson JM, Hurwitz BE, Llabre MM, Schneiderman N, Penedo FJ, Klimas NG.

Brain Behav Immun. 2008 Aug;22(6):901-11. doi: 10.1016/j.bbi.2008.01.001. Epub 2008 Mar 5.


Chronic fatigue syndrome: inflammation, immune function, and neuroendocrine interactions.

Klimas NG, Koneru AO.

Curr Rheumatol Rep. 2007 Dec;9(6):482-7. Review.


Fatigue: case definition and guidelines for collection, analysis, and presentation of immunization safety data.

Jones JF, Kohl KS, Ahmadipour N, Bleijenberg G, Buchwald D, Evengard B, Jason LA, Klimas NG, Lloyd A, McCleary K, Oleske JM, White PD; Brighton Collaboration Fatigue Working Group.

Vaccine. 2007 Aug 1;25(31):5685-96. Epub 2007 Mar 12. No abstract available.


Chronic fatigue syndrome is associated with diminished intracellular perforin.

Maher KJ, Klimas NG, Fletcher MA.

Clin Exp Immunol. 2005 Dec;142(3):505-11.


Sympathoimmune anomalies underlying the response to stressful challenge in human immunodeficiency virus spectrum disease.

Hurwitz BE, Brownley KA, Motivala SJ, Milanovich JR, Kibler JL, Fillion L, LeBlanc WG, Kumar M, Klimas NG, Fletcher MA, Schneiderman N.

Psychosom Med. 2005 Sep-Oct;67(5):798-806.


Stress-associated changes in the steady-state expression of latent Epstein-Barr virus: implications for chronic fatigue syndrome and cancer.

Glaser R, Padgett DA, Litsky ML, Baiocchi RA, Yang EV, Chen M, Yeh PE, Klimas NG, Marshall GD, Whiteside T, Herberman R, Kiecolt-Glaser J, Williams MV.

Brain Behav Immun. 2005 Mar;19(2):91-103.


HIV, metabolic syndrome X, inflammation, oxidative stress, and coronary heart disease risk : role of protease inhibitor exposure.

Hurwitz BE, Klimas NG, Llabre MM, Maher KJ, Skyler JS, Bilsker MS, McPherson-Baker S, Lawrence PJ, Laperriere AR, Greeson JM, Klaus JR, Lawrence R, Schneiderman N.

Cardiovasc Toxicol. 2004;4(3):303-16.


Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS.

Gonzalez JS, Penedo FJ, Antoni MH, Durán RE, McPherson-Baker S, Ironson G, Isabel Fernandez M, Klimas NG, Fletcher MA, Schneiderman N.

Health Psychol. 2004 Jul;23(4):413-418. doi: 10.1037/0278-6133.23.4.413.


Human immunodeficiency virus type 1 pharmacogenomics in clinical practice: relevance of HIV-1 drug resistance testing (Part 2).

Patarca R, Isava A, Campo R, Rodriguez NJ, Nunez E, Alter M, Marchette M, Sanabia MM, Mitchell C, Rivera D, Scott G, Jayaweera D, Moreno J, Boulanger C, Kolber M, Mask CW, Sierra EM, Vallejo R, Page JB, Klimas NG, Fletcher M.

J Environ Pathol Toxicol Oncol. 2003;22(4):235-79. Review.


Human immunodeficiency virus type 1 pharmacogenomics in clinical practice: relevance of HIV-1 drug resistance testing (Part 1).

Patarca R, Isava A, Campo R, Rodriguez NJ, Nunez E, Alter M, Marchette M, Sanabia MM, Mitchell C, Rivera D, Scott G, Jayaweera D, Moreno J, Boulanger C, Kolber M, Mask CW, Sierra EM, Vallejo R, Page JB, Klimas NG, Fletcher MA.

J Environ Pathol Toxicol Oncol. 2003;22(3):201-34. Review.


Psychological distress is associated with decreased memory helper T-cell and B-cell counts in pre-AIDS HIV seropositive men and women but only in those with low viral load.

Motivala SJ, Hurwitz BE, Llabre MM, Klimas NG, Fletcher MA, Antoni MH, LeBlanc WG, Schneiderman N.

Psychosom Med. 2003 Jul-Aug;65(4):627-35.


Quantitative fluorescence measures for determination of intracellular perforin content.

Maher KJ, Klimas NG, Hurwitz B, Schiff R, Fletcher MA.

Clin Diagn Lab Immunol. 2002 Nov;9(6):1248-52.


Autonomic and cardiovascular function in HIV spectrum disease: early indications of cardiac pathophysiology.

Brownley KA, Milanovich JR, Motivala SJ, Schneiderman N, Fillion L, Graves JA, Klimas NG, Fletcher MA, Hurwitz BE.

Clin Auton Res. 2001 Oct;11(5):319-26.


Cytokine and other immunologic markers in chronic fatigue syndrome and their relation to neuropsychological factors.

Patarca-Montero R, Antoni M, Fletcher MA, Klimas NG.

Appl Neuropsychol. 2001;8(1):51-64.


Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive men.

McPherson-Baker S, Malow RM, Penedo F, Jones DL, Schneiderman N, Klimas NG.

AIDS Care. 2000 Aug;12(4):399-404.


Serum neopterin and somatization in women with chemical intolerance, depressives, and normals.

Bell IR, Patarca R, Baldwin CM, Klimas NG, Schwartz GE, Hardin EE.

Neuropsychobiology. 1998;38(1):13-8.


Individual differences in neural sensitization and the role of context in illness from low-level environmental chemical exposures.

Bell IR, Schwartz GE, Baldwin CM, Hardin EE, Klimas NG, Kline JP, Patarca R, Song ZY.

Environ Health Perspect. 1997 Mar;105 Suppl 2:457-66. Review.


Immunological correlates of disease severity in pediatric slow progressors with human immunodeficiency virus type 1 infection.

Patarca R, Sandler D, Maher K, Hutto C, Martin NL, Klimas NG, Scott GB, Fletcher MA.

AIDS Res Hum Retroviruses. 1996 Jul 20;12(11):1063-8.


Patterns of immune, neuroendocrine, and cardiovascular stress responses in asymptomatic HIV seropositive and seronegative men.

Starr KR, Antoni MH, Hurwitz BE, Rodriquez MS, Ironson G, Fletcher MA, Kumar M, Patarca R, Lutgendorf SK, Quillian RE, Klimas NG, Schneiderman N.

Int J Behav Med. 1996;3(2):135-62. No abstract available.


Predictors of survival in human immunodeficiency virus type 1-seropositive intravenous drug users.

Page JB, Lai S, Fletcher MA, Patarca R, Smith PC, Lai HC, Klimas NG.

Clin Diagn Lab Immunol. 1996 Jan;3(1):51-60.


Lung cancer in patients with human immunodeficiency virus infection.

Flores MR, Sridhar KS, Thurer RJ, Saldana M, Raub WA Jr, Klimas NG.

Am J Clin Oncol. 1995 Feb;18(1):59-66.


Adoptive CD8+ T-cell immunotherapy of AIDS patients with Kaposi's sarcoma.

Patarca R, Klimas NG, Walling J, Sandler D, Friedlander A, Jin XQ, García MN, Fletcher MA.

Crit Rev Oncog. 1995;6(3-6):179-234. Review.


Megestrol acetate in patients with AIDS-related cachexia.

Von Roenn JH, Armstrong D, Kotler DP, Cohn DL, Klimas NG, Tchekmedyian NS, Cone L, Brennan PJ, Weitzman SA.

Ann Intern Med. 1994 Sep 15;121(6):393-9.


Delayed-type hypersensitivity skin tests are an independent predictor of human immunodeficiency virus disease progression. Department of Veterans Affairs Cooperative Study Group.

Gordin FM, Hartigan PM, Klimas NG, Zolla-Pazner SB, Simberkoff MS, Hamilton JD.

J Infect Dis. 1994 Apr;169(4):893-7.


Absence of HIV transmission from an infected dentist to his patients. An epidemiologic and DNA sequence analysis.

Dickinson GM, Morhart RE, Klimas NG, Bandea CI, Laracuente JM, Bisno AL.

JAMA. 1993 Apr 14;269(14):1802-6.


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