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Items: 1 to 50 of 113

1.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 May 16. pii: e8289. doi: 10.15252/emmm.201708289. [Epub ahead of print]

2.

Potent Inhibition of hERG Channels by the Over-the-Counter Antidiarrheal Agent Loperamide.

Klein MG, Haigney MCP, Mehler PS, Fatima N, Flagg TP, Krantz MJ.

JACC Clin Electrophysiol. 2016 Dec;2(7):784-789. doi: 10.1016/j.jacep.2016.07.008. Epub 2016 Sep 14.

PMID:
29759761
3.

Reply: Labeling and Drug Safety of Loperamide: Time for a Proactive Approach?

Haigney MC, Klein MG, Flagg TP, Fatima N, Mehler PS, Krantz MJ.

JACC Clin Electrophysiol. 2017 Apr;3(4):422-423. doi: 10.1016/j.jacep.2017.03.001. Epub 2017 Apr 17. No abstract available.

PMID:
29759459
4.

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.

Iwatani-Yoshihara M, Ito M, Klein MG, Yamamoto T, Yonemori K, Tanaka T, Miwa M, Morishita D, Endo S, Tjhen R, Qin L, Nakanishi A, Maezaki H, Kawamoto T.

J Med Chem. 2017 Jul 13;60(13):5759-5771. doi: 10.1021/acs.jmedchem.7b00461. Epub 2017 Jun 20.

PMID:
28586220
5.

Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes.

Lanier M, Cole DC, Istratiy Y, Klein MG, Schwartz PA, Tjhen R, Jennings A, Hixon MS.

J Med Chem. 2017 Jun 22;60(12):5209-5215. doi: 10.1021/acs.jmedchem.6b01224. Epub 2017 Jun 9.

6.

Sex Pheromone Dosages and Release Point Densities for Mating Disruption of Ostrinia furnacalis (Lepidoptera: Crambidae) in NE China Corn Fields.

Chen RZ, Jow CK, Klein MG, Jia YD, Zhang DY, Li LB.

Environ Entomol. 2017 Aug 1;46(4):916-925. doi: 10.1093/ee/nvx098.

PMID:
28535309
7.

Role of suppression of the inward rectifier current in terminal action potential repolarization in the failing heart.

Klein MG, Shou M, Stohlman J, Solhjoo S, Haigney M, Tidwell RR, Goldstein RE, Flagg TP, Haigney MC.

Heart Rhythm. 2017 Aug;14(8):1217-1223. doi: 10.1016/j.hrthm.2017.04.001. Epub 2017 Apr 8.

PMID:
28396172
8.

Plasma matrix metalloproteinase-9 levels predict intensive care unit mortality early after severe traumatic brain injury.

Simon D, Evaldt J, Nabinger DD, Fontana MF, Klein MG, do Amaral Gomes J, Regner A.

Brain Inj. 2017;31(3):390-395. doi: 10.1080/02699052.2016.1259501. Epub 2017 Feb 3.

PMID:
28156136
9.

Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia.

Nabinger DD, Mazzoleni LE, Sander GB, Mazzoleni F, Osório MC, Klein MG, Rech TF, Basso da Silva L, de Moraes GS, Cristovam RA, Nardelli EF, Francesconi CF, Simon D.

Genet Mol Res. 2016 Sep 16;15(3). doi: 10.4238/gmr.15038734.

PMID:
27706745
10.

Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition.

Wang H, Klein MG, Snell G, Lane W, Zou H, Levin I, Li K, Sang BC.

J Mol Biol. 2016 Jul 3;428(13):2769-79. doi: 10.1016/j.jmb.2016.05.012. Epub 2016 May 21.

PMID:
27220631
11.

Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors.

Katoh T, Takai T, Yukawa T, Tsukamoto T, Watanabe E, Mototani H, Arita T, Hayashi H, Nakagawa H, Klein MG, Zou H, Sang BC, Snell G, Nakada Y.

Bioorg Med Chem. 2016 Jun 1;24(11):2466-75. doi: 10.1016/j.bmc.2016.04.008. Epub 2016 Apr 4.

PMID:
27117263
12.

Scratch resistance of the ventral skin surface in four snake species (Squamata, Serpentes).

Klein MG, Gorb SN.

Zoology (Jena). 2016 Apr;119(2):81-96. doi: 10.1016/j.zool.2015.12.006. Epub 2016 Jan 3.

PMID:
26874374
13.

Captures of Ostrinia furnacalis (Lepidoptera: Crambidae) With Sex Pheromone Traps in NE China Corn and Soybeans.

Chen RZ, Li LB, Klein MG, Li QY, Li PP, Sheng CF.

Environ Entomol. 2016 Feb;45(1):207-15. doi: 10.1093/ee/nvv143. Epub 2015 Sep 11.

PMID:
26362111
14.

Mating Disruption or Mass Trapping, Compared With Chemical Insecticides, for Suppression of Chilo suppressalis (Lepidoptera: Crambidae) in Northeastern China.

Chen RZ, Klein MG, Sheng CF, Li QY, Li Y, Li LB, Hung X.

J Econ Entomol. 2014 Oct 1;107(5):1828-38. doi: 10.1603/EC14148.

PMID:
26309273
15.

Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate.

Wang H, Klein MG, Zou H, Lane W, Snell G, Levin I, Li K, Sang BC.

Nat Struct Mol Biol. 2015 Jul;22(7):581-5. doi: 10.1038/nsmb.3049. Epub 2015 Jun 22.

PMID:
26098317
16.

Mass trapping Popillia quadriguttata using Popillia japonica (Coleoptera: Scarabaeidae) pheromone and floral lures in northeastern China.

Chen RZ, Klein MG, Li QY, Li Y.

Environ Entomol. 2014 Jun;43(3):774-81. doi: 10.1603/EN13319. Epub 2014 Apr 28.

PMID:
24780142
17.

Use of pheromone timed insecticide applications integrated with mating disruption or mass trapping against Ostrinia furnacalis (Lepidoptera: Pyralidae) in sweet corn.

Chen RZ, Klein MG, Sheng CF, Li Y, Shao DX, Li QY.

Environ Entomol. 2013 Dec;42(6):1390-9. doi: 10.1603/EN13143. Epub 2013 Nov 25.

PMID:
24280487
18.

Emergency department patient flow simulations using spreadsheets.

Klein MG, Reinhardt G.

Simul Healthc. 2012 Feb;7(1):40-7. doi: 10.1097/SIH.0b013e3182301005.

PMID:
22228282
19.

Olfactory and visual responses of the longlegged chafer Hoplia spectabilis Medvedev (Coleoptera: Scarabaeidae) in Qinghai Province, China.

Zhang QH, Ma JH, Yang QQ, Byers JA, Klein MG, Zhao FY, Luo YQ.

Pest Manag Sci. 2011 Feb;67(2):162-9. doi: 10.1002/ps.2045.

PMID:
20981740
20.

Structural determinants underlying photoprotection in the photoactive orange carotenoid protein of cyanobacteria.

Wilson A, Kinney JN, Zwart PH, Punginelli C, D'Haene S, Perreau F, Klein MG, Kirilovsky D, Kerfeld CA.

J Biol Chem. 2010 Jun 11;285(24):18364-75. doi: 10.1074/jbc.M110.115709. Epub 2010 Apr 5.

21.

Field evaluation of essential oils for reducing attraction by the Japanese beetle (Coleoptera: Scarabaeidae).

Youssef NN, Oliver JB, Ranger CM, Reding ME, Moyseenko JJ, Klein MG, Pappas RS.

J Econ Entomol. 2009 Aug;102(4):1551-8.

PMID:
19736768
22.

Identification and structural analysis of a novel carboxysome shell protein with implications for metabolite transport.

Klein MG, Zwart P, Bagby SC, Cai F, Chisholm SW, Heinhorst S, Cannon GC, Kerfeld CA.

J Mol Biol. 2009 Sep 18;392(2):319-33. doi: 10.1016/j.jmb.2009.03.056. Epub 2009 Mar 27.

PMID:
19328811
23.

Isolation and activity of Xenorhabdus antimicrobial compounds against the plant pathogens Erwinia amylovora and Phytophthora nicotianae.

Böszörményi E, Ersek T, Fodor A, Fodor AM, Földes LS, Hevesi M, Hogan JS, Katona Z, Klein MG, Kormány A, Pekár S, Szentirmai A, Sztaricskai F, Taylor RA.

J Appl Microbiol. 2009 Sep;107(3):746-59. doi: 10.1111/j.1365-2672.2009.04249.x. Epub 2009 Mar 23.

24.

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.

Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL.

Bioorg Med Chem. 2009 Feb 15;17(4):1527-33. doi: 10.1016/j.bmc.2009.01.024. Epub 2009 Jan 20.

25.

Surface-applied insecticide treatments for quarantine control of Japanese beetle, Popillia japonica Newman (Coleoptera: Scarabaeidae), larvae in field-grown nursery plants.

Oliver JB, Reding ME, Youssef NN, Klein MG, Bishop BL, Lewis PA.

Pest Manag Sci. 2009 Apr;65(4):381-90. doi: 10.1002/ps.1701.

PMID:
19165744
26.

Activation of (Na+ + K+)-ATPase modulates cardiac L-type Ca2+ channel function.

Lee DI, Klein MG, Zhu W, Xiao RP, Gerzanich V, Xu KY.

Mol Pharmacol. 2009 Apr;75(4):774-81. doi: 10.1124/mol.108.052597. Epub 2009 Jan 2.

27.

Crystal structure of a near-full-length archaeal MCM: functional insights for an AAA+ hexameric helicase.

Brewster AS, Wang G, Yu X, Greenleaf WB, Carazo JM, Tjajadi M, Klein MG, Chen XS.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20191-6. doi: 10.1073/pnas.0808037105. Epub 2008 Dec 10.

28.

Drench treatments for management of larval Japanese beetle (Coleoptera: Scarabaeidae) in field-grown balled and burlapped nursery plants.

Oliver JB, Reding ME, Dennis SO, Moyseenko JJ, Youssef NN, Klein MG, Callcott AM, James SS, McAnally LR, Bishop BL.

J Econ Entomol. 2008 Aug;101(4):1158-66.

PMID:
18767724
29.

Identifying and assessing interests and concerns of priority populations for work-site programs to promote physical activity.

Phipps E, Madison N, Pomerantz SC, Klein MG.

Health Promot Pract. 2010 Jan;11(1):71-8. doi: 10.1177/1524839908318165. Epub 2008 Jun 6.

PMID:
18540005
30.

Actual and perceived activity levels in polio survivors and older controls: a longitudinal study.

Klein MG, Braitman LE, Costello R, Keenan MA, Esquenazi A.

Arch Phys Med Rehabil. 2008 Feb;89(2):297-303. doi: 10.1016/j.apmr.2007.08.156.

PMID:
18226654
31.

The structure of a DnaB-family replicative helicase and its interactions with primase.

Wang G, Klein MG, Tokonzaba E, Zhang Y, Holden LG, Chen XS.

Nat Struct Mol Biol. 2008 Jan;15(1):94-100. Epub 2007 Dec 23.

PMID:
18157148
32.

Xenorhabdus antibiotics: a comparative analysis and potential utility for controlling mastitis caused by bacteria.

Furgani G, Böszörményi E, Fodor A, Máthé-Fodor A, Forst S, Hogan JS, Katona Z, Klein MG, Stackebrandt E, Szentirmai A, Sztaricskai F, Wolf SL.

J Appl Microbiol. 2008 Mar;104(3):745-58. Epub 2007 Nov 1.

33.

Mechanisms of resistance and adaptation to thapsigargin in androgen-independent prostate cancer PC3 and DU145 cells.

Lee DI, Sumbilla C, Lee M, Natesavelalar C, Klein MG, Ross DD, Inesi G, Hussain A.

Arch Biochem Biophys. 2007 Aug 1;464(1):19-27. Epub 2007 Apr 16.

PMID:
17475205
34.

Chlorpyrifos immersion to eliminate third instars of Japanese beetle (Coleoptera: Scarabaeidae) in balled and burlapped trees and subsequent treatment effects on red maple.

Oliver JB, Reding ME, Klein MG, Youssef NN, Mannion CM, Bishop B, James SS, Callcott AM.

J Econ Entomol. 2007 Apr;100(2):307-14.

PMID:
17461051
35.

Phenylephrine hypertrophy, Ca2+-ATPase (SERCA2), and Ca2+ signaling in neonatal rat cardiac myocytes.

Prasad AM, Ma H, Sumbilla C, Lee DI, Klein MG, Inesi G.

Am J Physiol Cell Physiol. 2007 Jun;292(6):C2269-75. Epub 2007 Feb 7.

36.

The APOBEC-2 crystal structure and functional implications for the deaminase AID.

Prochnow C, Bransteitter R, Klein MG, Goodman MF, Chen XS.

Nature. 2007 Jan 25;445(7126):447-51. Epub 2006 Dec 24.

PMID:
17187054
37.

Structure of the Epstein-Barr virus major envelope glycoprotein.

Szakonyi G, Klein MG, Hannan JP, Young KA, Ma RZ, Asokan R, Holers VM, Chen XS.

Nat Struct Mol Biol. 2006 Nov;13(11):996-1001. Epub 2006 Oct 29.

PMID:
17072314
38.

Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.

Lilyestrom W, Klein MG, Zhang R, Joachimiak A, Chen XS.

Genes Dev. 2006 Sep 1;20(17):2373-82.

39.
40.

Survival of adult Tiphia vernalis (Hymenoptera: Tiphiidae) after insecticide, fungicide, and herbicide exposure in laboratory bioassays.

Oliver JB, Reding ME, Moyseenko JJ, Klein MG, Mannion CM, Bishop B.

J Econ Entomol. 2006 Apr;99(2):288-94.

PMID:
16686125
41.

Trapping Phyllophaga spp. (Coleoptera: Scarabaeidae: Melolonthinae) in the United States and Canada using sex attractants.

Robbins PS, Alm SR, Armstrong C, Averill AL, Baker TC, Bauernfiend RJ, Baxendale FP, Braman SK, Brandenburg RL, Cash DB, Couch GJ, Cowles RS, Crocker RL, DeLamar ZD, Dittl TG, Fitzpatrick SM, Flanders KL, Forgatsch T, Gibb TJ, Gill BD, Gilrein DO, Gorsuch CS, Hammond AM, Hastings PD, Held DW, Heller PR, Hiskes RT, Holliman JL, Hudson WG, Klein MG, Krischik VL, Lee DJ, Linn CE Jr, Luce NJ, MacKenzie KE, Mannion CM, Polavarapu S, Potter DA, Roelofs WL, Royals BM, Salsbury GA, Schiff NM, Shetlar DJ, Skinner M, Sparks BL, Sutschek JA, Sutschek TP, Swier SR, Sylvia MM, Vickers NJ, Vittum PJ, Weidman R, Weber DC, Williamson RC, Villani MG.

J Insect Sci. 2006;6:1-124. doi: 10.1673/2006_06_39.1.

42.
43.

Ca2+ sparks in skeletal muscle.

Klein MG, Schneider MF.

Prog Biophys Mol Biol. 2006 Nov;92(3):308-32. Epub 2005 Jul 1. Review.

PMID:
16125755
45.

Lung cancer detection in patients with airflow obstruction identified in a primary care outpatient practice.

Bechtel JJ, Kelley WA, Coons TA, Klein MG, Slagel DD, Petty TL.

Chest. 2005 Apr;127(4):1140-5.

PMID:
15821187
46.

Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes.

Seth M, Sumbilla C, Mullen SP, Lewis D, Klein MG, Hussain A, Soboloff J, Gill DL, Inesi G.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16683-8. Epub 2004 Nov 16.

47.

Musculoskeletal pain in polio survivors and strength-matched controls.

Klein MG, Keenan MA, Esquenazi A, Costello R, Polansky M.

Arch Phys Med Rehabil. 2004 Oct;85(10):1679-83.

PMID:
15468030
48.

Structure of the actin crosslinking core of fimbrin.

Klein MG, Shi W, Ramagopal U, Tseng Y, Wirtz D, Kovar DR, Staiger CJ, Almo SC.

Structure. 2004 Jun;12(6):999-1013.

49.

Cell-specific expression of SERCA, the exogenous Ca2+ transport ATPase, in cardiac myocytes.

Ma H, Sumbilla CM, Farrance IK, Klein MG, Inesi G.

Am J Physiol Cell Physiol. 2004 Mar;286(3):C556-64. Epub 2003 Oct 30.

50.

Tracheal replacement in rabbits with a new composite silicone-metallic prosthesis.

Dodge-Khatami A, Niessen HW, Koole LH, Klein MG, van Gulik TM, de Mol BA.

Asian Cardiovasc Thorac Ann. 2003 Sep;11(3):245-9.

PMID:
14514557

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