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Items: 1 to 50 of 170

1.

Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment.

Lüke F, Blazquez R, Yamaci RF, Lu X, Pregler B, Hannus S, Menhart K, Hellwig D, Wester HJ, Kropf S, Heudobler D, Grosse J, Moosbauer J, Hutterer M, Hau P, Riemenschneider MJ, Bayerlová M, Bleckmann A, Polzer B, Beißbarth T, Klein CA, Pukrop T.

Oncotarget. 2018 Apr 10;9(27):18844-18857. doi: 10.18632/oncotarget.24787. eCollection 2018 Apr 10.

2.

Understanding Tattoos in Medicolegal Assessments.

Klein CA, Kenedi C.

J Am Acad Psychiatry Law. 2018 Mar;46(1):93-101.

PMID:
29618541
3.

Effect of At-home and In-office Bleaching on Marginal Microleakage in Composite Resin Restorations using Two Adhesive Systems.

Klein CA Jr, da Silva D, Reston EG, Borghetti DL, Zimmer R.

J Contemp Dent Pract. 2018 Mar 1;19(3):248-252.

PMID:
29603692
4.

Author Correction: Influence of soil moisture on codenitrification fluxes from a urea-affected pasture soil.

Clough TJ, Lanigan GJ, de Klein CAM, Samad MS, Morales SE, Rex D, Bakken LR, Johns C, Condron LM, Grant J, Richards KG.

Sci Rep. 2018 Mar 7;8(1):4363. doi: 10.1038/s41598-018-22645-7.

5.

Single cell polarity in liquid phase facilitates tumour metastasis.

Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M.

Nat Commun. 2018 Feb 28;9(1):887. doi: 10.1038/s41467-018-03139-6.

6.

Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma.

Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, Markiewicz A, Weidele K, Czyz Z, Hohenleutner U, Hafner C, Haferkamp S, Berneburg M, Rümmele P, Ulmer A, Klein CA.

Nat Commun. 2018 Feb 9;9(1):595. doi: 10.1038/s41467-017-02674-y.

7.

The sentinel lymph node spread determines quantitatively melanoma seeding to non-sentinel lymph nodes and survival.

Ulmer A, Dietz K, Werner-Klein M, Häfner HM, Schulz C, Renner P, Weber F, Breuninger H, Röcken M, Garbe C, Fierlbeck G, Klein CA.

Eur J Cancer. 2018 Mar;91:1-10. doi: 10.1016/j.ejca.2017.12.002. Epub 2018 Jan 6.

PMID:
29316475
8.

Corrigendum: Mechanism of early dissemination and metastasis in Her2+ mammary cancer.

Harper KL, Sosa MS, Entenberg D, Hosseini H, Cheung JF, Nobre R, Avivar-Valderas A, Nagi C, Girnius N, Davis RJ, Farias EF, Condeelis J, Klein CA, Aguirre-Ghiso JA.

Nature. 2018 Jan 18;553(7688):366. doi: 10.1038/nature24666. Epub 2017 Dec 13.

PMID:
29236689
9.

Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer.

Hoffmann M, Pasch S, Schamberger T, Maneck M, Möhlendick B, Schumacher S, Brockhoff G, Knoefel WT, Izbicki J, Polzer B, Stoecklein NH, Klein CA.

Int J Cancer. 2018 Feb 15;142(4):833-843. doi: 10.1002/ijc.31108. Epub 2017 Nov 30.

PMID:
29044505
10.

Using alternative forage species to reduce emissions of the greenhouse gas nitrous oxide from cattle urine deposited onto soil.

Luo J, Balvert SF, Wise B, Welten B, Ledgard SF, de Klein CAM, Lindsey S, Judge A.

Sci Total Environ. 2018 Jan 1;610-611:1271-1280. doi: 10.1016/j.scitotenv.2017.08.186. Epub 2017 Aug 30.

PMID:
28851147
11.

Response to nitrogen addition reveals metabolic and ecological strategies of soil bacteria.

Samad MS, Johns C, Richards KG, Lanigan GJ, de Klein CAM, Clough TJ, Morales SE.

Mol Ecol. 2017 Oct;26(20):5500-5514. doi: 10.1111/mec.14275. Epub 2017 Aug 24.

PMID:
28752622
12.

Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma.

Schumacher S, Bartenhagen C, Hoffmann M, Will D, Fischer JC, Baldus SE, Vay C, Fluegen G, Dizdar L, Vallböhmer D, Klein CA, Knoefel WT, Stoecklein NH, Möhlendick B.

Br J Cancer. 2017 Aug 22;117(5):725-733. doi: 10.1038/bjc.2017.233. Epub 2017 Jul 20.

PMID:
28728164
13.

Influence of soil moisture on codenitrification fluxes from a urea-affected pasture soil.

Clough TJ, Lanigan GJ, de Klein CAM, Samad MS, Morales SE, Rex D, Bakken LR, Johns C, Condron LM, Grant J, Richards KG.

Sci Rep. 2017 May 19;7(1):2185. doi: 10.1038/s41598-017-02278-y. Erratum in: Sci Rep. 2018 Mar 7;8(1):4363.

14.

Early dissemination seeds metastasis in breast cancer.

Hosseini H, Obradović MM, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, Patwary N, Haunschild G, Gužvić M, Reimelt C, Grauvogl M, Eichner N, Weber F, Hartkopf AD, Taran FA, Brucker SY, Fehm T, Rack B, Buchholz S, Spang R, Meister G, Aguirre-Ghiso JA, Klein CA.

Nature. 2016 Dec 14. doi: 10.1038/nature20785. [Epub ahead of print]

15.

Mechanism of early dissemination and metastasis in Her2+ mammary cancer.

Harper KL, Sosa MS, Entenberg D, Hosseini H, Cheung JF, Nobre R, Avivar-Valderas A, Nagi C, Girnius N, Davis RJ, Farias EF, Condeelis J, Klein CA, Aguirre-Ghiso JA.

Nature. 2016 Dec 14. doi: 10.1038/nature20609. [Epub ahead of print] Erratum in: Nature. 2017 Dec 13;:.

16.

Erratum: Phylogenetic and functional potential links pH and N2O emissions in pasture soils.

Samad MS, Biswas A, Bakken LR, Clough TJ, de Klein CA, Richards KG, Lanigan GJ, Morales SE.

Sci Rep. 2016 Dec 6;6:37481. doi: 10.1038/srep37481. No abstract available.

17.

Phylogenetic and functional potential links pH and N2O emissions in pasture soils.

Samad MS, Biswas A, Bakken LR, Clough TJ, de Klein CA, Richards KG, Lanigan GJ, Morales SE.

Sci Rep. 2016 Oct 26;6:35990. doi: 10.1038/srep35990. Erratum in: Sci Rep. 2016 Dec 06;6:37481.

18.

Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes.

Suzuki T, Asami M, Hoffmann M, Lu X, Gužvić M, Klein CA, Perry AC.

Nat Commun. 2016 Sep 13;7:12676. doi: 10.1038/ncomms12676.

19.

High-Resolution Denitrification Kinetics in Pasture Soils Link N2O Emissions to pH, and Denitrification to C Mineralization.

Samad MS, Bakken LR, Nadeem S, Clough TJ, de Klein CA, Richards KG, Lanigan GJ, Morales SE.

PLoS One. 2016 Mar 18;11(3):e0151713. doi: 10.1371/journal.pone.0151713. eCollection 2016.

20.

Single-cell analysis of CTCs with diagnostic precision: opportunities and challenges for personalized medicine.

Alberter B, Klein CA, Polzer B.

Expert Rev Mol Diagn. 2016;16(1):25-38. doi: 10.1586/14737159.2016.1121099. Epub 2015 Dec 5. Review.

PMID:
26567956
21.

Deterministic Whole-Genome Amplification of Single Cells.

Czyż ZT, Klein CA.

Methods Mol Biol. 2015;1347:69-86. doi: 10.1007/978-1-4939-2990-0_5.

PMID:
26374310
22.

Effects of climate change on the delivery of soil-mediated ecosystem services within the primary sector in temperate ecosystems: a review and New Zealand case study.

Orwin KH, Stevenson BA, Smaill SJ, Kirschbaum MU, Dickie IA, Clothier BE, Garrett LG, van der Weerden TJ, Beare MH, Curtin D, de Klein CA, Dodd MB, Gentile R, Hedley C, Mullan B, Shepherd M, Wakelin SA, Bell N, Bowatte S, Davis MR, Dominati E, O'Callaghan M, Parfitt RL, Thomas SM.

Glob Chang Biol. 2015 Aug;21(8):2844-60. doi: 10.1111/gcb.12949. Epub 2015 Jun 8. Review.

PMID:
25891785
23.

A role for Rac1 activity in malignant progression of sebaceous skin tumors.

Frances D, Sharma N, Pofahl R, Maneck M, Behrendt K, Reuter K, Krieg T, Klein CA, Haase I, Niemann C.

Oncogene. 2015 Oct;34(43):5505-12. doi: 10.1038/onc.2014.471. Epub 2015 Feb 9.

PMID:
25659584
24.

Digital and divergent: sexual behaviors on the Internet.

Klein CA.

J Am Acad Psychiatry Law. 2014;42(4):495-503. Review.

PMID:
25492077
25.

Integrin expression in esophageal squamous cell carcinoma: loss of the physiological integrin expression pattern correlates with disease progression.

Vay C, Hosch SB, Stoecklein NH, Klein CA, Vallböhmer D, Link BC, Yekebas EF, Izbicki JR, Knoefel WT, Scheunemann P.

PLoS One. 2014 Nov 14;9(11):e109026. doi: 10.1371/journal.pone.0109026. eCollection 2014.

26.

Molecular profiling of single circulating tumor cells with diagnostic intention.

Polzer B, Medoro G, Pasch S, Fontana F, Zorzino L, Pestka A, Andergassen U, Meier-Stiegen F, Czyz ZT, Alberter B, Treitschke S, Schamberger T, Sergio M, Bregola G, Doffini A, Gianni S, Calanca A, Signorini G, Bolognesi C, Hartmann A, Fasching PA, Sandri MT, Rack B, Fehm T, Giorgini G, Manaresi N, Klein CA.

EMBO Mol Med. 2014 Nov;6(11):1371-86. doi: 10.15252/emmm.201404033.

27.

Combined genome and transcriptome analysis of single disseminated cancer cells from bone marrow of prostate cancer patients reveals unexpected transcriptomes.

Gužvić M, Braun B, Ganzer R, Burger M, Nerlich M, Winkler S, Werner-Klein M, Czyż ZT, Polzer B, Klein CA.

Cancer Res. 2014 Dec 15;74(24):7383-94. doi: 10.1158/0008-5472.CAN-14-0934. Epub 2014 Oct 15.

28.

Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer.

Neves RP, Raba K, Schmidt O, Honisch E, Meier-Stiegen F, Behrens B, Möhlendick B, Fehm T, Neubauer H, Klein CA, Polzer B, Sproll C, Fischer JC, Niederacher D, Stoecklein NH.

Clin Chem. 2014 Oct;60(10):1290-7. doi: 10.1373/clinchem.2014.222331.

29.

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.

Wang J, Lu X, Sakk V, Klein CA, Rudolph KL.

Blood. 2014 Nov 20;124(22):3237-40. doi: 10.1182/blood-2014-04-568055. Epub 2014 Sep 16.

30.

The masks of identities: who's who? Delusional misidentification syndromes.

Klein CA, Hirachan S.

J Am Acad Psychiatry Law. 2014;42(3):369-78. Review.

PMID:
25187290
31.

Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients.

Werner-Klein M, Proske J, Werno C, Schneider K, Hofmann HS, Rack B, Buchholz S, Ganzer R, Blana A, Seelbach-Göbel B, Nitsche U, Männel DN, Klein CA.

PLoS One. 2014 May 15;9(5):e97860. doi: 10.1371/journal.pone.0097860. eCollection 2014.

32.

Quantitative measurement of melanoma spread in sentinel lymph nodes and survival.

Ulmer A, Dietz K, Hodak I, Polzer B, Scheitler S, Yildiz M, Czyz Z, Lehnert P, Fehm T, Hafner C, Schanz S, Röcken M, Garbe C, Breuninger H, Fierlbeck G, Klein CA.

PLoS Med. 2014 Feb 18;11(2):e1001604. doi: 10.1371/journal.pmed.1001604. eCollection 2014 Feb.

33.

Reliable single cell array CGH for clinical samples.

Czyż ZT, Hoffmann M, Schlimok G, Polzer B, Klein CA.

PLoS One. 2014 Jan 21;9(1):e85907. doi: 10.1371/journal.pone.0085907. eCollection 2014.

34.

Molecular profiling of single Sca-1+/CD34+,- cells--the putative murine lung stem cells.

Hittinger M, Czyz ZT, Huesemann Y, Maneck M, Botteron C, Kaeufl S, Klein CA, Polzer B.

PLoS One. 2013 Dec 31;8(12):e83917. doi: 10.1371/journal.pone.0083917. eCollection 2013.

35.

Statistical analysis of nitrous oxide emission factors from pastoral agriculture field trials conducted in New Zealand.

Kelliher FM, Cox N, van der Weerden TJ, de Klein CA, Luo J, Cameron KC, Di HJ, Giltrap D, Rys G.

Environ Pollut. 2014 Mar;186:63-6. doi: 10.1016/j.envpol.2013.11.025. Epub 2013 Dec 20.

36.

Cancer dormancy: time to explore its clinical relevance.

Gužvić M, Klein CA.

Breast Cancer Res. 2013 Dec 20;15(6):321. doi: 10.1186/bcr3590.

37.

SUMOylation in Trypanosoma brucei.

Klein CA, Droll D, Clayton C.

PeerJ. 2013 Oct 8;1:e180. doi: 10.7717/peerj.180. eCollection 2013.

38.

Diagnostic leukapheresis enables reliable detection of circulating tumor cells of nonmetastatic cancer patients.

Fischer JC, Niederacher D, Topp SA, Honisch E, Schumacher S, Schmitz N, Zacarias Föhrding L, Vay C, Hoffmann I, Kasprowicz NS, Hepp PG, Mohrmann S, Nitz U, Stresemann A, Krahn T, Henze T, Griebsch E, Raba K, Rox JM, Wenzel F, Sproll C, Janni W, Fehm T, Klein CA, Knoefel WT, Stoecklein NH.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16580-5. doi: 10.1073/pnas.1313594110. Epub 2013 Sep 24.

39.

Selection and adaptation during metastatic cancer progression.

Klein CA.

Nature. 2013 Sep 19;501(7467):365-72. doi: 10.1038/nature12628.

PMID:
24048069
40.

Metastasis awakening: the challenges of targeting minimal residual cancer.

Polzer B, Klein CA.

Nat Med. 2013 Mar;19(3):274-5. doi: 10.1038/nm.3121. No abstract available.

PMID:
23467237
41.

Live deaths online: internet suicide and lethality.

Klein CA.

J Am Acad Psychiatry Law. 2012;40(4):530-6.

PMID:
23233475
42.

Sequence error storms and the landscape of mutations in cancer.

Kirsch S, Klein CA.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14289-90. doi: 10.1073/pnas.1212246109. Epub 2012 Aug 21. No abstract available.

43.

Losses at chromosome 4q are associated with poor survival in operable ductal pancreatic adenocarcinoma.

Luebke AM, Baudis M, Matthaei H, Vashist YK, Verde PE, Hosch SB, Erbersdobler A, Klein CA, Izbicki JR, Knoefel WT, Stoecklein NH.

Pancreatology. 2012 Jan-Feb;12(1):16-22. doi: 10.1016/j.pan.2011.11.001. Epub 2011 Nov 20.

PMID:
22487468
44.

Intentional ingestion and insertion of foreign objects: a forensic perspective.

Klein CA.

J Am Acad Psychiatry Law. 2012;40(1):119-26.

PMID:
22396349
45.

MAGE qPCR improves the sensitivity and accuracy of EBUS-TBNA for the detection of lymphatic cancer spread.

Cucuruz B, Dango S, Jurinovic V, Mayer O, Follo M, Böhm J, Freudenberg N, Elze M, Sienel W, Klein CA, Passlick B, Polzer B.

J Thorac Oncol. 2012 Apr;7(4):690-7. doi: 10.1097/JTO.0b013e31824294de.

46.
47.

Back-scattered electron imaging for leakage analysis of four retrofilling materials.

Chittoni SB, Martini T, Wagner MH, Da Rosa RA, Cavenago BC, Duarte MA, Klein CA Jr, Só MV.

Microsc Res Tech. 2012 Jun;75(6):796-800. doi: 10.1002/jemt.21128. Epub 2011 Dec 6.

PMID:
22147679
48.

www.mydrugdealer.com: Ethics and legal implications of Internet-based access to substances of abuse.

Klein CA, Kandel S.

J Am Acad Psychiatry Law. 2011;39(3):407-11.

PMID:
21908759
49.

Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium.

Chambers KF, Pearson JF, Pellacani D, Aziz N, Gužvić M, Klein CA, Lang SH.

J Biomed Sci. 2011 Jun 22;18:45. doi: 10.1186/1423-0127-18-45.

50.

Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres.

VerMilyea MD, Maneck M, Yoshida N, Blochberger I, Suzuki E, Suzuki T, Spang R, Klein CA, Perry AC.

EMBO J. 2011 May 4;30(9):1841-51. doi: 10.1038/emboj.2011.92. Epub 2011 Apr 5.

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