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Items: 1 to 50 of 54

1.

Synthesis of (+)-Pancratistatins via Catalytic Desymmetrization of Benzene.

Hernandez LW, Pospech J, Klöckner U, Bingham TW, Sarlah D.

J Am Chem Soc. 2017 Nov 8;139(44):15656-15659. doi: 10.1021/jacs.7b10351. Epub 2017 Oct 25.

PMID:
29059521
2.

NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes.

Villmow M, Klöckner U, Heymes C, Gekle M, Rueckschloss U.

Basic Res Cardiol. 2015 Sep;110(5):506. doi: 10.1007/s00395-015-0506-5. Epub 2015 Jul 15.

PMID:
26173391
3.

Direct inhibition, but indirect sensitization of pacemaker activity to sympathetic tone by the interaction of endotoxin with HCN-channels.

Ebelt H, Geißler I, Ruccius S, Otto V, Hoffmann S, Korth H, Klöckner U, Zhang Y, Li Y, Grossmann C, Rueckschloss U, Gekle M, Stieber J, Frantz S, Werdan K, Müller-Werdan U, Loppnow H.

Clin Exp Pharmacol Physiol. 2015 Aug;42(8):874-80. doi: 10.1111/1440-1681.12415.

PMID:
25933122
4.

Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains.

Klöckner U, Rueckschloss U, Grossmann C, Matzat S, Schumann K, Ebelt H, Müller-Werdan U, Loppnow H, Werdan K, Gekle M.

J Physiol. 2014 Mar 15;592(6):1199-211. doi: 10.1113/jphysiol.2013.268540. Epub 2013 Dec 23.

5.

Differential reduction of HCN channel activity by various types of lipopolysaccharide.

Klöckner U, Rueckschloss U, Grossmann C, Ebelt H, Müller-Werdan U, Loppnow H, Werdan K, Gekle M.

J Mol Cell Cardiol. 2011 Aug;51(2):226-35. doi: 10.1016/j.yjmcc.2011.05.004. Epub 2011 May 14.

PMID:
21609720
6.

Cardiac overexpression of the human 5-HT4 receptor in mice.

Gergs U, Baumann M, Böckler A, Buchwalow IB, Ebelt H, Fabritz L, Hauptmann S, Keller N, Kirchhof P, Klöckner U, Pönicke K, Rueckschloss U, Schmitz W, Werner F, Neumann J.

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H788-98. doi: 10.1152/ajpheart.00691.2009. Epub 2010 Jul 16.

7.

NADPH oxidase-derived superoxide impairs calcium transients and contraction in aged murine ventricular myocytes.

Rueckschloss U, Villmow M, Klöckner U.

Exp Gerontol. 2010 Oct;45(10):788-96. doi: 10.1016/j.exger.2010.05.002. Epub 2010 May 21.

PMID:
20493939
8.

Inotropic effects of L-lysine in the mammalian heart.

Boldt A, Gergs U, Frenker J, Simm A, Silber RE, Klöckner U, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Oct;380(4):293-301. doi: 10.1007/s00210-009-0439-3. Epub 2009 Aug 7.

PMID:
19662383
9.

The molecular chaperone hsp70 interacts with the cytosolic II-III loop of the Cav2.3 E-type voltage-gated Ca2+ channel.

Krieger A, Radhakrishnan K, Pereverzev A, Siapich SA, Banat M, Kamp MA, Leroy J, Klöckner U, Hescheler J, Weiergräber M, Schneider T.

Cell Physiol Biochem. 2006;17(3-4):97-110. Epub 2006 Mar 14.

10.

The cytosolic II-III loop of Cav2.3 provides an essential determinant for the phorbol ester-mediated stimulation of E-type Ca2+ channel activity.

Klöckner U, Pereverzev A, Leroy J, Krieger A, Vajna R, Pfitzer G, Hescheler J, Malécot CO, Schneider T.

Eur J Neurosci. 2004 May;19(10):2659-68.

PMID:
15147300
11.

Characterization of auto-regulation of the human cardiac alpha1 subunit of the L-type calcium channel: importance of the C-terminus.

Mikala G, Bodi I, Klockner U, Varadi M, Varadi G, Koch SE, Schwartz A.

Mol Cell Biochem. 2003 Aug;250(1-2):81-9.

PMID:
12962146
12.

Ca2+-sensitive regulation of E-type Ca2+ channel activity depends on an arginine-rich region in the cytosolic II-III loop.

Leroy J, Pereverzev A, Vajna R, Qin N, Pfitzer G, Hescheler J, Malécot CO, Schneider T, Klöckner U.

Eur J Neurosci. 2003 Aug;18(4):841-55.

PMID:
12925010
13.

Alternate splicing in the cytosolic II-III loop and the carboxy terminus of human E-type voltage-gated Ca(2+) channels: electrophysiological characterization of isoforms.

Pereverzev A, Leroy J, Krieger A, Malécot CO, Hescheler J, Pfitzer G, Klöckner U, Schneider T.

Mol Cell Neurosci. 2002 Oct;21(2):352-65.

PMID:
12401453
14.

Reduction of insulin secretion in the insulinoma cell line INS-1 by overexpression of a Ca(v)2.3 (alpha1E) calcium channel antisense cassette.

Pereverzev A, Vajna R, Pfitzer G, Hescheler J, Klöckner U, Schneider T.

Eur J Endocrinol. 2002 Jun;146(6):881-9.

15.

Functional coupling between 'R-type' Ca2+ channels and insulin secretion in the insulinoma cell line INS-1.

Vajna R, Klöckner U, Pereverzev A, Weiergräber M, Chen X, Miljanich G, Klugbauer N, Hescheler J, Perez-Reyes E, Schneider T.

Eur J Biochem. 2001 Feb;268(4):1066-75.

16.

Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channels.

Klöckner U, Lee JH, Cribbs LL, Daud A, Hescheler J, Pereverzev A, Perez-Reyes E, Schneider T.

Eur J Neurosci. 1999 Dec;11(12):4171-8.

PMID:
10594642
17.

Immunohistochemical detection of alpha1E voltage-gated Ca(2+) channel isoforms in cerebellum, INS-1 cells, and neuroendocrine cells of the digestive system.

Grabsch H, Pereverzev A, Weiergräber M, Schramm M, Henry M, Vajna R, Beattie RE, Volsen SG, Klöckner U, Hescheler J, Schneider T.

J Histochem Cytochem. 1999 Aug;47(8):981-94.

PMID:
10424882
18.

Isoforms of alpha1E voltage-gated calcium channels in rat cerebellar granule cells--detection of major calcium channel alpha1-transcripts by reverse transcription-polymerase chain reaction.

Schramm M, Vajna R, Pereverzev A, Tottene A, Klöckner U, Pietrobon D, Hescheler J, Schneider T.

Neuroscience. 1999;92(2):565-75.

PMID:
10408605
19.

Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family.

Lee JH, Daud AN, Cribbs LL, Lacerda AE, Pereverzev A, Klöckner U, Schneider T, Perez-Reyes E.

J Neurosci. 1999 Mar 15;19(6):1912-21.

20.

New isoform of the neuronal Ca2+ channel alpha1E subunit in islets of Langerhans and kidney--distribution of voltage-gated Ca2+ channel alpha1 subunits in cell lines and tissues.

Vajna R, Schramm M, Pereverzev A, Arnhold S, Grabsch H, Klöckner U, Perez-Reyes E, Hescheler J, Schneider T.

Eur J Biochem. 1998 Oct 1;257(1):274-85.

21.

Structural diversity of the voltage-dependent Ca2+ channel alpha1E-subunit.

Pereverzev A, Klöckner U, Henry M, Grabsch H, Vajna R, Olyschläger S, Viatchenko-Karpinski S, Schröder R, Hescheler J, Schneider T.

Eur J Neurosci. 1998 Mar;10(3):916-25.

PMID:
9753159
22.

cAMP-dependent phosphorylation sites and macroscopic activity of recombinant cardiac L-type calcium channels.

Mikala G, Klöckner U, Varadi M, Eisfeld J, Schwartz A, Varadi G.

Mol Cell Biochem. 1998 Aug;185(1-2):95-109.

PMID:
9746216
23.

Properties of three COOH-terminal splice variants of a human cardiac L-type Ca2+-channel alpha1-subunit.

Klöckner U, Mikala G, Eisfeld J, Iles DE, Strobeck M, Mershon JL, Schwartz A, Varadi G.

Am J Physiol. 1997 Mar;272(3 Pt 2):H1372-81.

PMID:
9087614
24.

Inhibition of cloned human L-type cardiac calcium channels by 2,3-butanedione monoxime does not require PKA-dependent phosphorylation sites.

Eisfeld J, Mikala G, Varadi G, Schwartz A, Klöckner U.

Biochem Biophys Res Commun. 1997 Jan 23;230(3):489-92.

PMID:
9015346
26.

Lack of involvement of protein kinase A phosphorylation in voltage-dependent facilitation of the activity of human cardiac L-type calcium channels.

Eisfeld J, Mikala G, Schwartz A, Varadi G, Klöckner U.

Biochem Biophys Res Commun. 1996 Apr 16;221(2):446-53.

PMID:
8619875
27.

Involvement of the carboxyl-terminal region of the alpha 1 subunit in voltage-dependent inactivation of cardiac calcium channels.

Klöckner U, Mikala G, Varadi M, Varadi G, Schwartz A.

J Biol Chem. 1995 Jul 21;270(29):17306-10.

30.

Intracellular pH modulates the availability of vascular L-type Ca2+ channels.

Klöckner U, Isenberg G.

J Gen Physiol. 1994 Apr;103(4):647-63.

32.
33.

Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.

Schultz D, Mikala G, Yatani A, Engle DB, Iles DE, Segers B, Sinke RJ, Weghuis DO, Klöckner U, Wakamori M, et al.

Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6228-32.

34.

Beta-subunit expression is required for cAMP-dependent increase of cloned cardiac and vascular calcium channel currents.

Klöckner U, Itagaki K, Bodi I, Schwartz A.

Pflugers Arch. 1992 Mar;420(3-4):413-5.

PMID:
1317953
36.

ATP suppresses activity of Ca(2+)-activated K+ channels by Ca2+ chelation.

Klöckner U, Isenberg G.

Pflugers Arch. 1992 Jan;420(1):101-5.

PMID:
1553255
37.
38.
39.

Carbon monoxide inhibits depolarization-induced Ca rise and increases cyclic GMP in visceral smooth muscle cells.

Trischmann U, Klöckner U, Isenberg G, Utz J, Ullrich V.

Biochem Pharmacol. 1991 Jan 15;41(2):237-41.

PMID:
1846546
40.

L-type Ca-channels: similar Q10 of Ca-, Ba- and Na-conductance points to the importance of ion-channel interaction.

Klöckner U, Schiefer A, Isenberg G.

Pflugers Arch. 1990 Feb;415(5):638-41.

PMID:
2158070
41.
42.

Pharmacological modulation of calcium and potassium channels in isolated vascular smooth muscle cells.

Klöckner U, Trieschmann U, Isenberg G.

Arzneimittelforschung. 1989 Jan;39(1A):120-6.

PMID:
2541731
43.

Ca-antagonistic effects of adenosine in guinea pig atrial cells.

Cerbai E, Klöckner U, Isenberg G.

Am J Physiol. 1988 Oct;255(4 Pt 2):H872-8.

PMID:
2845817
44.

The alpha subunit of the GTP binding protein activates muscarinic potassium channels of the atrium.

Cerbai E, Klöckner U, Isenberg G.

Science. 1988 Jun 24;240(4860):1782-3.

PMID:
2454511
45.

Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes.

Klöckner U, Isenberg G.

Am J Physiol. 1987 Dec;253(6 Pt 2):H1601-11.

PMID:
2447792
46.
47.
48.
49.

Ca-tolerant guinea-pig ventricular myocytes as isolated by pronase in the presence of 250 microM free calcium.

Bendukidze Z, Isenberg G, Klöckner U.

Basic Res Cardiol. 1985;80 Suppl 1:13-7.

PMID:
2581546
50.

The electrophysiological properties of the isolated adult heart cell: an overview.

Isenberg G, Klöckner U.

Basic Res Cardiol. 1985;80 Suppl 2:51-4.

PMID:
2415108

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