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Items: 1 to 50 of 92

1.

Deep spontaneous molecular remission in a patient with congenital acute myeloid leukemia expressing a novel MOZ-p300 fusion transcript.

Ikawa Y, Nishimura R, Maeba H, Fujiki T, Kuroda R, Noguchi K, Fukuda M, Mase S, Araki R, Mitani Y, Sato T, Terui K, Ito E, Kitabayashi I, Yachie A.

Leuk Lymphoma. 2018 Feb 12:1-3. doi: 10.1080/10428194.2018.1434885. [Epub ahead of print] No abstract available.

PMID:
29431567
2.

Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells.

Shima H, Takamatsu-Ichihara E, Shino M, Yamagata K, Katsumoto T, Aikawa Y, Fujita S, Koseki H, Kitabayashi I.

Blood. 2018 Apr 19;131(16):1833-1845. doi: 10.1182/blood-2017-05-787226. Epub 2018 Jan 25.

PMID:
29371181
3.

Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia.

Fujita S, Honma D, Adachi N, Araki K, Takamatsu E, Katsumoto T, Yamagata K, Akashi K, Aoyama K, Iwama A, Kitabayashi I.

Leukemia. 2018 Apr;32(4):855-864. doi: 10.1038/leu.2017.300. Epub 2017 Sep 27.

PMID:
28951561
4.

Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development.

Ogoh H, Yamagata K, Nakao T, Sandell LL, Yamamoto A, Yamashita A, Tanga N, Suzuki M, Abe T, Kitabayashi I, Watanabe T, Sakai D.

Sci Rep. 2017 Sep 20;7(1):11922. doi: 10.1038/s41598-017-11745-5.

5.

EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice.

Dong Y, Isono KI, Ohbo K, Endo TA, Ohara O, Maekawa M, Toyama Y, Ito C, Toshimori K, Helin K, Ogonuki N, Inoue K, Ogura A, Yamagata K, Kitabayashi I, Koseki H.

Mol Cell Biol. 2017 Sep 12;37(19). pii: e00082-17. doi: 10.1128/MCB.00082-17. Print 2017 Oct 1.

6.

[I. Identification of a Possible Therapeutic Target for Chondrosarcoma with IDH Mutant Inhibitors].

Nakagawa M, Nakatani F, Kitabayashi I.

Gan To Kagaku Ryoho. 2017 Mar;44(3):212-216. Japanese. No abstract available.

PMID:
28400543
7.

MLL is essential for NUP98-HOXA9-induced leukemia.

Shima Y, Yumoto M, Katsumoto T, Kitabayashi I.

Leukemia. 2017 Oct;31(10):2200-2210. doi: 10.1038/leu.2017.62. Epub 2017 Feb 17.

PMID:
28210005
8.

The roles of Polycomb group proteins in hematopoietic stem cells and hematological malignancies.

Takamatsu-Ichihara E, Kitabayashi I.

Int J Hematol. 2016 Jun;103(6):634-42. doi: 10.1007/s12185-016-2011-5. Epub 2016 Apr 16. Review.

PMID:
27086351
9.

A Synthetic Polymer Scaffold Reveals the Self-Maintenance Strategies of Rat Glioma Stem Cells by Organization of the Advantageous Niche.

Tabu K, Muramatsu N, Mangani C, Wu M, Zhang R, Kimura T, Terashima K, Bizen N, Kimura R, Wang W, Murota Y, Kokubu Y, Nobuhisa I, Kagawa T, Kitabayashi I, Bradley M, Taga T.

Stem Cells. 2016 May;34(5):1151-62. doi: 10.1002/stem.2299. Epub 2016 Feb 19.

10.

IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis.

Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, Kitabayashi I, Tashiro F, Namiki H, Kondo T, Semba K, Aburatani H, Taya Y, Nakagama H, Ohki R.

Sci Rep. 2016 Jan 12;6:19174. doi: 10.1038/srep19174.

11.

[IDH mutations activate Hoxa9/Meis1 and hypoxia pathways in acute myeloid leukemia model mice].

Ogawara Y, Kitabayashi I.

Rinsho Ketsueki. 2015 Aug;56(8):1045-52. doi: 10.11406/rinketsu.56.1045. Japanese.

PMID:
26345565
12.

IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia.

Ogawara Y, Katsumoto T, Aikawa Y, Shima Y, Kagiyama Y, Soga T, Matsunaga H, Seki T, Araki K, Kitabayashi I.

Cancer Res. 2015 May 15;75(10):2005-16. doi: 10.1158/0008-5472.CAN-14-2200. Epub 2015 Mar 20.

13.

Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells.

Aikawa Y, Yamagata K, Katsumoto T, Shima Y, Shino M, Stanley ER, Cleary ML, Akashi K, Tenen DG, Kitabayashi I.

Cancer Sci. 2015 Mar;106(3):227-36. doi: 10.1111/cas.12593. Epub 2015 Feb 12.

14.

Detection of the G17V RHOA mutation in angioimmunoblastic T-cell lymphoma and related lymphomas using quantitative allele-specific PCR.

Nakamoto-Matsubara R, Sakata-Yanagimoto M, Enami T, Yoshida K, Yanagimoto S, Shiozawa Y, Nanmoku T, Satomi K, Muto H, Obara N, Kato T, Kurita N, Yokoyama Y, Izutsu K, Ota Y, Sanada M, Shimizu S, Komeno T, Sato Y, Ito T, Kitabayashi I, Takeuchi K, Nakamura N, Ogawa S, Chiba S.

PLoS One. 2014 Oct 13;9(10):e109714. doi: 10.1371/journal.pone.0109714. eCollection 2014.

15.

Hes1 suppresses acute myeloid leukemia development through FLT3 repression.

Kato T, Sakata-Yanagimoto M, Nishikii H, Ueno M, Miyake Y, Yokoyama Y, Asabe Y, Kamada Y, Muto H, Obara N, Suzukawa K, Hasegawa Y, Kitabayashi I, Uchida K, Hirao A, Yagita H, Kageyama R, Chiba S.

Leukemia. 2015 Mar;29(3):576-85. doi: 10.1038/leu.2014.281. Epub 2014 Sep 19.

PMID:
25234168
16.

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers.

Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, Arai Y, Kanai Y, Taki T, Abe T, Kiyonari H, Shimoda K, Ohshima K, Horii A, Shima H, Taniwaki M, Yamaguchi R, Morishita K.

Nat Commun. 2014 Feb 26;5:3393. doi: 10.1038/ncomms4393.

17.

The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells.

Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A.

Stem Cell Reports. 2014 Jan 23;2(2):145-52. doi: 10.1016/j.stemcr.2013.12.008. eCollection 2014 Feb 11.

18.

MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters.

Okuda H, Kawaguchi M, Kanai A, Matsui H, Kawamura T, Inaba T, Kitabayashi I, Yokoyama A.

Nucleic Acids Res. 2014 Apr;42(7):4241-56. doi: 10.1093/nar/gkt1394. Epub 2014 Jan 23.

19.

Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia.

Suzuki M, Yamagata K, Shino M, Aikawa Y, Akashi K, Watanabe T, Kitabayashi I.

Cancer Sci. 2014 Mar;105(3):315-23. doi: 10.1111/cas.12347. Epub 2014 Feb 13.

20.

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K.

Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20.

PMID:
24269920
21.

Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.

Shima H, Yamagata K, Aikawa Y, Shino M, Koseki H, Shimada H, Kitabayashi I.

Int J Hematol. 2014 Jan;99(1):21-31. doi: 10.1007/s12185-013-1466-x. Epub 2013 Nov 21.

PMID:
24258712
22.

MLL becomes functional through intra-molecular interaction not by proteolytic processing.

Yokoyama A, Ficara F, Murphy MJ, Meisel C, Hatanaka C, Kitabayashi I, Cleary ML.

PLoS One. 2013 Sep 10;8(9):e73649. doi: 10.1371/journal.pone.0073649. eCollection 2013.

23.

PML-RARα and its phosphorylation regulate pml oligomerization and HIPK2 stability.

Shima Y, Honma Y, Kitabayashi I.

Cancer Res. 2013 Jul 15;73(14):4278-88. doi: 10.1158/0008-5472.CAN-12-3814. Epub 2013 May 30.

24.

Roles of AML1/RUNX1 in T-cell malignancy induced by loss of p53.

Shimizu K, Yamagata K, Kurokawa M, Mizutani S, Tsunematsu Y, Kitabayashi I.

Cancer Sci. 2013 Aug;104(8):1033-8. doi: 10.1111/cas.12199. Epub 2013 Jun 20.

25.

Interactomic approach for evaluating nucleophosmin-binding proteins as biomarkers for Ewing's sarcoma.

Haga A, Ogawara Y, Kubota D, Kitabayashi I, Murakami Y, Kondo T.

Electrophoresis. 2013 Jun;34(11):1670-8. doi: 10.1002/elps.201200661.

PMID:
23483572
26.

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies.

Iwanami A, Gini B, Zanca C, Matsutani T, Assuncao A, Nael A, Dang J, Yang H, Zhu S, Kohyama J, Kitabayashi I, Cavenee WK, Cloughesy TF, Furnari FB, Nakamura M, Toyama Y, Okano H, Mischel PS.

Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4339-44. doi: 10.1073/pnas.1217602110. Epub 2013 Feb 25.

27.

MOZ increases p53 acetylation and premature senescence through its complex formation with PML.

Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3895-900. doi: 10.1073/pnas.1300490110. Epub 2013 Feb 19.

28.

[Transcriptional regulation].

Katsumoto T, Kitabayashi I.

Nihon Rinsho. 2012 Apr;70 Suppl 2:75-8. Japanese. No abstract available.

PMID:
23133931
29.

β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.

Satow R, Shitashige M, Jigami T, Fukami K, Honda K, Kitabayashi I, Yamada T.

Gastroenterology. 2012 Mar;142(3):572-81. doi: 10.1053/j.gastro.2011.11.041. Epub 2011 Dec 9.

PMID:
22155184
30.

Deregulated transcription factors in leukemia.

Shima Y, Kitabayashi I.

Int J Hematol. 2011 Aug;94(2):134-141. doi: 10.1007/s12185-011-0905-9. Epub 2011 Aug 9. Review.

PMID:
21823042
31.

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

Mishima Y, Miyagi S, Saraya A, Negishi M, Endoh M, Endo TA, Toyoda T, Shinga J, Katsumoto T, Chiba T, Yamaguchi N, Kitabayashi I, Koseki H, Iwama A.

Blood. 2011 Sep 1;118(9):2443-53. doi: 10.1182/blood-2011-01-331892. Epub 2011 Jul 13.

32.

Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.

Yokoyama A, Ficara F, Murphy MJ, Meisel C, Naresh A, Kitabayashi I, Cleary ML.

J Cell Sci. 2011 Jul 1;124(Pt 13):2208-19. doi: 10.1242/jcs.080523.

33.

Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein.

Ozeki C, Sawai Y, Shibata T, Kohno T, Okamoto K, Yokota J, Tashiro F, Tanuma S, Sakai R, Kawase T, Kitabayashi I, Taya Y, Ohki R.

J Biol Chem. 2011 May 20;286(20):18251-60. doi: 10.1074/jbc.M110.208587. Epub 2011 Mar 28.

34.

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2.

Aikawa Y, Katsumoto T, Zhang P, Shima H, Shino M, Terui K, Ito E, Ohno H, Stanley ER, Singh H, Tenen DG, Kitabayashi I.

Nat Med. 2010 May;16(5):580-5, 1p following 585. doi: 10.1038/nm.2122. Epub 2010 Apr 25.

35.

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.

Yokoyama A, Lin M, Naresh A, Kitabayashi I, Cleary ML.

Cancer Cell. 2010 Feb 17;17(2):198-212. doi: 10.1016/j.ccr.2009.12.040.

36.

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX.

Yamagata K, Kitabayashi I.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1355-60. doi: 10.1016/j.bbrc.2009.10.156. Epub 2009 Nov 4.

PMID:
19895790
37.

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells.

Kitoh A, Ono M, Naoe Y, Ohkura N, Yamaguchi T, Yaguchi H, Kitabayashi I, Tsukada T, Nomura T, Miyachi Y, Taniuchi I, Sakaguchi S.

Immunity. 2009 Oct 16;31(4):609-20. doi: 10.1016/j.immuni.2009.09.003. Epub 2009 Oct 1.

38.

Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons.

Hibiya K, Katsumoto T, Kondo T, Kitabayashi I, Kudo A.

Dev Biol. 2009 May 15;329(2):176-90. doi: 10.1016/j.ydbio.2009.02.021. Epub 2009 Feb 27.

39.

Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.

Rokudai S, Aikawa Y, Tagata Y, Tsuchida N, Taya Y, Kitabayashi I.

J Biol Chem. 2009 Jan 2;284(1):237-44. doi: 10.1074/jbc.M805101200. Epub 2008 Nov 10.

40.

PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation.

Shima Y, Shima T, Chiba T, Irimura T, Pandolfi PP, Kitabayashi I.

Mol Cell Biol. 2008 Dec;28(23):7126-38. doi: 10.1128/MCB.00897-08. Epub 2008 Sep 22.

41.

Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis.

Katsumoto T, Yoshida N, Kitabayashi I.

Cancer Sci. 2008 Aug;99(8):1523-7. doi: 10.1111/j.1349-7006.2008.00865.x. Review.

42.

Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis.

Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T.

J Biol Chem. 2008 Sep 5;283(36):24420-5. doi: 10.1074/jbc.M802217200. Epub 2008 Jul 11.

43.

RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis.

Marshall LJ, Moore AC, Ohki M, Kitabayashi I, Patterson D, Ornelles DA.

J Virol. 2008 Jul;82(13):6395-408. doi: 10.1128/JVI.00043-08. Epub 2008 Apr 16.

44.

Phosphorylation of Runx1 at Ser249, Ser266, and Ser276 is dispensable for bone marrow hematopoiesis and thymocyte differentiation.

Tachibana M, Tezuka C, Muroi S, Nishimoto S, Katsumoto T, Nakajima A, Kitabayashi I, Taniuchi I.

Biochem Biophys Res Commun. 2008 Apr 11;368(3):536-42. doi: 10.1016/j.bbrc.2008.01.124. Epub 2008 Feb 6.

PMID:
18261462
45.

Chromatin regulation by AML1 complex.

Yoshida H, Kitabayashi I.

Int J Hematol. 2008 Jan;87(1):19-24. doi: 10.1007/s12185-007-0004-0. Epub 2007 Nov 27.

PMID:
18224409
46.

Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1.

Sugimoto N, Kitabayashi I, Osano S, Tatsumi Y, Yugawa T, Narisawa-Saito M, Matsukage A, Kiyono T, Fujita M.

Mol Biol Cell. 2008 Mar;19(3):1007-21. Epub 2007 Dec 27.

47.

Phosphorylation of PML is essential for activation of C/EBP epsilon and PU.1 to accelerate granulocytic differentiation.

Tagata Y, Yoshida H, Nguyen LA, Kato H, Ichikawa H, Tashiro F, Kitabayashi I.

Leukemia. 2008 Feb;22(2):273-80. Epub 2007 Nov 8.

PMID:
17989716
48.

PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.

Yoshida H, Ichikawa H, Tagata Y, Katsumoto T, Ohnishi K, Akao Y, Naoe T, Pandolfi PP, Kitabayashi I.

Mol Cell Biol. 2007 Aug;27(16):5819-34. Epub 2007 Jun 11.

49.

Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription.

Li XL, Arai Y, Harada H, Shima Y, Yoshida H, Rokudai S, Aikawa Y, Kimura A, Kitabayashi I.

Oncogene. 2007 Nov 8;26(51):7231-9. Epub 2007 May 28.

PMID:
17533375
50.

[Transcription regulation and leukemia].

Kitabayashi I.

Nihon Rinsho. 2007 Jan 28;65 Suppl 1:41-5. Review. Japanese. No abstract available.

PMID:
17474393

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