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Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance.

Arimura T, Muchir A, Kuwahara M, Morimoto S, Ishikawa T, Du CK, Zhan DY, Nakao S, Machida N, Tanaka R, Yamane Y, Hayashi T, Kimura A.

Am J Physiol Heart Circ Physiol. 2018 Feb 16. doi: 10.1152/ajpheart.00696.2017. [Epub ahead of print]


The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.

Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K.

Sci Signal. 2018 Feb 6;11(516). pii: eaan3638. doi: 10.1126/scisignal.aan3638.


Effect of high-frequency near-infrared diode laser irradiation on periodontal tissues during experimental tooth movement in rats.

Gunji H, Kunimatsu R, Tsuka Y, Yoshimi Y, Sumi K, Awada T, Nakajima K, Kimura A, Hiraki T, Hirose N, Yanoshita M, Tanimoto K.

Lasers Surg Med. 2018 Feb 5. doi: 10.1002/lsm.22797. [Epub ahead of print]


[A Case of Appendiceal Mucinous Adenocarcinoma Detected with a Bladder Tumor].

Tsutsumi S, Murata A, Yamauchi Y, Okano K, Yokoyama H, Kimura A, Ishizawa Y, Umehara M, Kato M, Hashimoto N, Umehara Y, Nishikawa S, Takahashi K, Morita T.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1425-1427. Japanese.


Long-Term Imatinib Treatment for Patients with Unresectable or Recurrent Gastrointestinal Stromal Tumors.

Ogata K, Kimura A, Nakazawa N, Suzuki M, Yanoma T, Ubukata Y, Iwamatsu K, Kogure N, Yanai M, Kuwano H.

Digestion. 2018 Feb 1;97(1):20-25. doi: 10.1159/000484102. [Epub ahead of print]


Cutting Edge: Nqo1 Regulates Irritant Contact Hypersensitivity against Croton Oil through Maintenance of Dendritic Epidermal T Cells.

Kitajima M, Kimura A, Suzuki H.

J Immunol. 2018 Mar 1;200(5):1555-1559. doi: 10.4049/jimmunol.1701389. Epub 2018 Jan 29.


Draft genome sequence of Streptomyces hyaluromycini MB-PO13T, a hyaluromycin producer.

Harunari E, Komaki H, Ichikawa N, Hosoyama A, Kimura A, Hamada M, Igarashi Y.

Stand Genomic Sci. 2018 Jan 11;13:2. doi: 10.1186/s40793-017-0286-7. eCollection 2018.


Forensic application of epidermal AQP3 expression to determination of wound vitality in human compressed neck skin.

Ishida Y, Kuninaka Y, Nosaka M, Shimada E, Hata S, Yamamoto H, Hashizume Y, Kimura A, Furukawa F, Kondo T.

Int J Legal Med. 2018 Jan 22. doi: 10.1007/s00414-018-1780-1. [Epub ahead of print]


Tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division.

Sugioka K, Fielmich LE, Mizumoto K, Bowerman B, van den Heuvel S, Kimura A, Sawa H.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E954-E963. doi: 10.1073/pnas.1712052115. Epub 2018 Jan 18.


Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis.

Kimura A, Takemura M, Serrero G, Yoshikura N, Hayashi Y, Saito K, Inuzuka T.

J Neurooncol. 2018 Jan 16. doi: 10.1007/s11060-017-2742-z. [Epub ahead of print]


Delayed administration of BQ788, an ETB antagonist, after experimental traumatic brain injury promotes recovery of blood-brain barrier function and reduction of cerebral edema in mice.

Michinaga S, Kimura A, Hatanaka S, Minami S, Asano A, Ikushima Y, Matsui S, Toriyama Y, Fujii M, Koyama Y.

J Neurotrauma. 2018 Jan 9. doi: 10.1089/neu.2017.5421. [Epub ahead of print]


Robust Subthreshold Cross-modal Modulation of Auditory Response by Cutaneous Electrical Stimulation in First- and Higher-order Auditory Thalamic Nuclei.

Kimura A, Imbe H.

Neuroscience. 2018 Feb 21;372:161-180. doi: 10.1016/j.neuroscience.2017.12.051. Epub 2018 Jan 6.


Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts.

Kunimatsu R, Gunji H, Tsuka Y, Yoshimi Y, Awada T, Sumi K, Nakajima K, Kimura A, Hiraki T, Abe T, Naoto H, Yanoshita M, Tanimoto K.

Lasers Med Sci. 2018 Jan 4. doi: 10.1007/s10103-017-2426-0. [Epub ahead of print]


Loss of chromosome Y in blood, but not in brain, of suicide completers.

Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I.

PLoS One. 2018 Jan 4;13(1):e0190667. doi: 10.1371/journal.pone.0190667. eCollection 2018.


Drug-induced Pressure Ulcers in a Middle-aged Patient with Early-stage Parkinson's Disease.

Hayashi Y, Shibata H, Kudo T, Nishida S, Ishikawa R, Moriya C, Suzuki A, Kimura A, Inuzuka T.

Intern Med. 2017 Dec 27. doi: 10.2169/internalmedicine.9700-17. [Epub ahead of print]


Pharmacist-led intervention in the multidisciplinary team approach optimizes heart failure medication.

Suzuki M, Matsue Y, Izumi S, Kimura A, Hashimoto T, Otomo K, Saito H, Suzuki M, Kato Y, Funakoshi R.

Heart Vessels. 2017 Dec 4. doi: 10.1007/s00380-017-1099-8. [Epub ahead of print]


Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis.

Kimura A, Ogata K, Altan B, Yokobori T, Mochiki E, Yanai M, Kogure N, Yanoma T, Suzuki M, Bai T, Kuwano H.

World J Gastroenterol. 2017 Nov 14;23(42):7541-7550. doi: 10.3748/wjg.v23.i42.7541.


Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.

Ishida Y, Kimura A, Nosaka M, Kuninaka Y, Hemmi H, Sasaki I, Kaisho T, Mukaida N, Kondo T.

Sci Rep. 2017 Dec 4;7(1):16833. doi: 10.1038/s41598-017-17007-8.


Direct evidence of hidden local spin polarization in a centrosymmetric superconductor LaO0.55 F0.45BiS2.

Wu SL, Sumida K, Miyamoto K, Taguchi K, Yoshikawa T, Kimura A, Ueda Y, Arita M, Nagao M, Watauchi S, Tanaka I, Okuda T.

Nat Commun. 2017 Dec 4;8(1):1919. doi: 10.1038/s41467-017-02058-2.


An asymmetric attraction model for the diversity and robustness of cell arrangement in nematodes.

Yamamoto K, Kimura A.

Development. 2017 Dec 1;144(23):4437-4449. doi: 10.1242/dev.154609.


Enzymatically synthesized megalo-type isomaltosaccharides enhance the barrier function of the tight junction in the intestinal epithelium.

Hara H, Kume S, Iizuka T, Fujimoto Y, Kimura A.

Biosci Biotechnol Biochem. 2017 Nov 27:1-7. doi: 10.1080/09168451.2017.1398065. [Epub ahead of print]


Cerebrospinal Fluid C-C Motif Chemokine Ligand 2 Correlates with Brain Atrophy and Cognitive Impairment in Alzheimer's Disease.

Kimura A, Yoshikura N, Hayashi Y, Inuzuka T.

J Alzheimers Dis. 2018;61(2):581-588. doi: 10.3233/JAD-170519.


Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch.

Zhao J, Nishimura Y, Kimura A, Ozawa K, Kondo T, Tanaka T, Yoshizumi M.

Sci Rep. 2017 Nov 23;7(1):16128. doi: 10.1038/s41598-017-15867-8.


Phenotypic expression of a novel desmin gene mutation: hypertrophic cardiomyopathy followed by systemic myopathy.

Harada H, Hayashi T, Nishi H, Kusaba K, Koga Y, Koga Y, Nonaka I, Kimura A.

J Hum Genet. 2018 Feb;63(2):249-254. doi: 10.1038/s10038-017-0383-x. Epub 2017 Nov 22.


A Testis-Specific Long Non-Coding RNA, lncRNA-Tcam1, Regulates Immune-Related Genes in Mouse Male Germ Cells.

Kurihara M, Otsuka K, Matsubara S, Shiraishi A, Satake H, Kimura AP.

Front Endocrinol (Lausanne). 2017 Nov 2;8:299. doi: 10.3389/fendo.2017.00299. eCollection 2017.


Yacon fructans (Smallanthus sonchifolius) extraction, characterization and activation of macrophages to phagocyte yeast cells.

Paredes LLR, Smiderle FR, Santana-Filho AP, Kimura A, Iacomini M, Sassaki GL.

Int J Biol Macromol. 2018 Mar;108:1074-1081. doi: 10.1016/j.ijbiomac.2017.11.034. Epub 2017 Nov 7.



Sinert R, Levy P, Bernstein JA, Body R, Sivilotti MLA, Moellman J, Schranz J, Baptista J, Kimura A, Nothaft W; CAMEO study group.

J Allergy Clin Immunol Pract. 2017 Nov - Dec;5(6):1803-1804. doi: 10.1016/j.jaip.2017.07.040. No abstract available.


The 25-question Geriatric Locomotive Function Scale predicts the risk of recurrent falls in postoperative patients with cervical myelopathy.

Kimura A, Takeshita K, Inoue H, Seichi A, Kawasaki Y, Yoshii T, Inose H, Furuya T, Takeuchi K, Matsunaga S, Seki S, Tsushima M, Imagama S, Koda M, Yamazaki M, Mori K, Nishimura H, Endo K, Yamada K, Sato K, Okawa A.

J Orthop Sci. 2018 Jan;23(1):185-189. doi: 10.1016/j.jos.2017.10.006. Epub 2017 Oct 31.


An Aliphatic Ester Diisopropyl Sebacate Exhibited an Adjuvant Effect on Fluorescein Isothiocyanate-Induced Contact Hypersensitivity Mouse Models.

Kurohane K, Kimura A, Terasawa R, Kobayashi K, Suzuki W, Matsuoka T, Imai Y.

Biol Pharm Bull. 2018 Jan 1;41(1):147-150. doi: 10.1248/bpb.b17-00723. Epub 2017 Oct 27.


Immunohistochemical analysis on aquaporin-1 and aquaporin-3 in skin wounds from the aspects of wound age determination.

Ishida Y, Kuninaka Y, Furukawa F, Kimura A, Nosaka M, Fukami M, Yamamoto H, Kato T, Shimada E, Hata S, Takayasu T, Eisenmenger W, Kondo T.

Int J Legal Med. 2018 Jan;132(1):237-242. doi: 10.1007/s00414-017-1725-0. Epub 2017 Oct 28.


Prolonged duration of nonequilibrated Dirac fermions in neutral topological insulators.

Sumida K, Ishida Y, Zhu S, Ye M, Pertsova A, Triola C, Kokh KA, Tereshchenko OE, Balatsky AV, Shin S, Kimura A.

Sci Rep. 2017 Oct 26;7(1):14080. doi: 10.1038/s41598-017-14308-w.


MKL1 expressed in macrophages contributes to the development of murine colitis.

An J, Nagaishi T, Watabe T, Naruse TK, Watanabe M, Kimura A.

Sci Rep. 2017 Oct 20;7(1):13650. doi: 10.1038/s41598-017-13629-0.


Postmortem distribution of chlorpyrifos-methyl, fenitrothion, and their metabolites in body fluids and organ tissues of an intoxication case.

Takayasu T, Yamamoto H, Ishida Y, Nosaka M, Kawaguchi M, Kuninaka Y, Kimura A, Kondo T.

Leg Med (Tokyo). 2017 Nov;29:44-50. doi: 10.1016/j.legalmed.2017.10.002. Epub 2017 Oct 4.


Serum Quantitative Proteomic Analysis Reveals Soluble EGFR To Be a Marker of Insulin Resistance in Male Mice and Humans.

Kyohara M, Shirakawa J, Okuyama T, Kimura A, Togashi Y, Tajima K, Hirano H, Terauchi Y.

Endocrinology. 2017 Dec 1;158(12):4152-4164. doi: 10.1210/en.2017-00339.


Characteristics of patients with fragility hip fractures in the northern Kyushu district in Japan: a multicenter prospective registry based on an electronic data capture system.

Oyamada A, Matsumoto Y, Wakata Y, Kimura A, Ikuta K, Tsuchiya K, Tayama N, Tomari S, Miyahara H, Mae T, Shiraishi H, Saito T, Arizono T, Kaji K, Mawatari T, Fujiwara M, Sakimura R, Shin K, Ninomiya K, Nakaie K, Antoku Y, Tokunaga S, Nakashima N, Iwamoto Y, Nakashima Y.

J Bone Miner Metab. 2017 Oct 12. doi: 10.1007/s00774-017-0869-9. [Epub ahead of print]


Composition of the microbiota in forestomach fluids and feces of Japanese Black calves with white scours.

Nakamura SI, Kim YH, Takashima K, Kimura A, Nagai K, Ichijo T, Sato S.

J Anim Sci. 2017 Sep;95(9):3949-3960. doi: 10.2527/jas2017.1431.


Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study.

Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Nishimura H, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S.

Global Spine J. 2017 Oct;7(7):636-641. doi: 10.1177/2192568217716144. Epub 2017 Jul 20.


FIR haplodeficiency promotes splicing to pyruvate kinase M2 in mice thymic lymphoma tissues revealed by six-plex tandem mass tag quantitative proteomic analysis.

Kimura A, Kitamura K, Ailiken G, Satoh M, Minamoto T, Tanaka N, Nomura F, Matsushita K.

Oncotarget. 2017 Jul 7;8(40):67955-67965. doi: 10.18632/oncotarget.19061. eCollection 2017 Sep 15.


Edaravone Prevents Retinal Degeneration in Adult Mice Following Optic Nerve Injury.

Akiyama G, Azuchi Y, Guo X, Noro T, Kimura A, Harada C, Namekata K, Harada T.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4908-4914. doi: 10.1167/iovs.17-22250.


Clinical findings of a probable case of MM2-cortical-type sporadic Creutzfeldt-Jakob disease with antibodies to anti-N-terminus of α-enolase.

Hayashi Y, Yamada M, Kimura A, Asano T, Satoh K, Kitamoto T, Yoneda M, Inuzuka T.

Prion. 2017 Nov 2;11(6):454-464. doi: 10.1080/19336896.2017.1377876. Epub 2017 Oct 30.


Corrigendum to Anti-C1q autoantibodies in patients with neuromyelitis optica spectrum disorders" [J. Neuroimmunol. 310. (2017) 150-157].

Yoshikura N, Kimura A, Hayashi Y, Inuzuka T.

J Neuroimmunol. 2017 Nov 15;312:66. doi: 10.1016/j.jneuroim.2017.09.009. No abstract available.


A Long Noncoding RNA, lncRNA-Amhr2, Plays a Role in Amhr2 Gene Activation in Mouse Ovarian Granulosa Cells.

Kimura AP, Yoneda R, Kurihara M, Mayama S, Matsubara S.

Endocrinology. 2017 Nov 1;158(11):4105-4121. doi: 10.1210/en.2017-00619.


In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.

Seki S, Nomura T, Nishizawa M, Yamamoto H, Ishii H, Matsuoka S, Shiino T, Sato H, Mizuta K, Sakawaki H, Miura T, Naruse TK, Kimura A, Matano T.

PLoS Pathog. 2017 Sep 20;13(9):e1006638. doi: 10.1371/journal.ppat.1006638. eCollection 2017 Sep.


The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis.

Guo X, Namekata K, Kimura A, Harada C, Harada T.

Am J Pathol. 2017 Dec;187(12):2876-2885. doi: 10.1016/j.ajpath.2017.08.012. Epub 2017 Sep 15.


Assessment and management of pain in newborns hospitalized in a Neonatal Intensive Care Unit: a cross-sectional study.

Sposito NPB, Rossato LM, Bueno M, Kimura AF, Costa T, Guedes DMB.

Rev Lat Am Enfermagem. 2017 Sep 12;25:e2931. doi: 10.1590/1518-8345.1665.2931. English, Portuguese, Spanish.


Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study.

Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Matsuoka Y, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S.

Global Spine J. 2017 Sep;7(6):560-566. doi: 10.1177/2192568217700115. Epub 2017 Apr 11.


ASK1 in neurodegeneration.

Guo X, Namekata K, Kimura A, Harada C, Harada T.

Adv Biol Regul. 2017 Dec;66:63-71. doi: 10.1016/j.jbior.2017.08.003. Epub 2017 Sep 1. Review.


Development of idursulfase therapy for mucopolysaccharidosis type II (Hunter syndrome): the past, the present and the future.

Whiteman DA, Kimura A.

Drug Des Devel Ther. 2017 Aug 23;11:2467-2480. doi: 10.2147/DDDT.S139601. eCollection 2017. Review.


Small molecule AT7867 proliferates PDX1-expressing pancreatic progenitor cells derived from human pluripotent stem cells.

Kimura A, Toyoda T, Nishi Y, Nasu M, Ohta A, Osafune K.

Stem Cell Res. 2017 Oct;24:61-68. doi: 10.1016/j.scr.2017.08.010. Epub 2017 Aug 17.

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