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Items: 1 to 50 of 92

1.

The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses.

Azouz NP, Ynga-Durand MA, Caldwell JM, Jain A, Rochman M, Fischesser DM, Ray LM, Bedard MC, Mingler MK, Forney C, Eilerman M, Kuhl JT, He H, Biagini Myers JM, Mukkada VA, Putnam PE, Khurana Hershey GK, Kottyan LC, Wen T, Martin LJ, Rothenberg ME.

Sci Transl Med. 2018 Jun 6;10(444). pii: eaap9736. doi: 10.1126/scitranslmed.aap9736.

PMID:
29875205
2.

Ohio Pediatric Asthma Repository: Opportunities to Revise Care Practices to Decrease Time to Physiologic Readiness for Discharge.

Simmons JM, Biagini Myers JM, Martin LJ, Kercsmar CM, Schuler CL, Pilipenko VV, Kroner JW, He H, Austin SR, Nguyen HT, Ross KR, McCoy KS, Alter SJ, Gunkelman SM, Vauthy PA, Khurana Hershey GK.

Hosp Pediatr. 2018 Jun;8(6):305-313. doi: 10.1542/hpeds.2017-0085. Epub 2018 May 15.

PMID:
29764909
3.

TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state.

Rochman Y, Dienger-Stambaugh K, Richgels PK, Lewkowich IP, Kartashov AV, Barski A, Khurana Hershey GK, Leonard WJ, Singh H.

Sci Signal. 2018 Mar 13;11(521). pii: eaam8858. doi: 10.1126/scisignal.aam8858.

PMID:
29535264
4.

High number of early respiratory infections in association with allergic sensitization to mold promotes childhood asthma.

Perez Ramirez L, Wendroth H, Martin LJ, Pilipenko VV, He H, Kroner J, Ryan PH, LeMasters GK, Lockey JE, Bernstein DI, Khurana Hershey GK, Biagini Myers JM.

J Allergy Clin Immunol. 2018 May;141(5):1921-1924.e4. doi: 10.1016/j.jaci.2017.11.058. Epub 2018 Feb 21. No abstract available.

PMID:
29378287
5.

Adjunctive Pharmacotherapies in Children With Asthma Exacerbations Requiring Continuous Albuterol Therapy: Findings From The Ohio Pediatric Asthma Repository.

Shein SL, Farhan O, Morris N, Mahmood N, Alter SJ, Biagini Myers JM, Gunkelman SM, Kercsmar CM, Khurana Hershey GK, Martin LJ, McCoy KS, Ruddy JR, Ross KR.

Hosp Pediatr. 2018 Jan 5. pii: hpeds.2017-0088. doi: 10.1542/hpeds.2017-0088. [Epub ahead of print]

PMID:
29305409
6.

Obstruction phenotype as a predictor of asthma severity and instability in children.

Sorkness RL, Zoratti EM, Kattan M, Gergen PJ, Evans MD, Visness CM, Gill M, Khurana Hershey GK, Kercsmar CM, Liu AH, O'Connor GT, Pongracic JA, Pillai D, Sorkness CA, Togias A, Wood RA, Busse WW.

J Allergy Clin Immunol. 2017 Nov 14. pii: S0091-6749(17)31752-9. doi: 10.1016/j.jaci.2017.09.047. [Epub ahead of print]

PMID:
29146272
7.

Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci.

Martin LJ, He H, Collins MH, Abonia JP, Biagini Myers JM, Eby M, Johansson H, Kottyan LC, Khurana Hershey GK, Rothenberg ME.

J Allergy Clin Immunol. 2018 May;141(5):1690-1698. doi: 10.1016/j.jaci.2017.09.046. Epub 2017 Nov 10.

PMID:
29129581
8.

Staphylococcal Biofilms in Atopic Dermatitis.

Gonzalez T, Biagini Myers JM, Herr AB, Khurana Hershey GK.

Curr Allergy Asthma Rep. 2017 Oct 23;17(12):81. doi: 10.1007/s11882-017-0750-x. Review.

PMID:
29063212
9.

Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.

Zhang X, Biagini Myers JM, Yadagiri VK, Ulm A, Chen X, Weirauch MT, Khurana Hershey GK, Ji H.

PLoS One. 2017 Oct 13;12(10):e0186150. doi: 10.1371/journal.pone.0186150. eCollection 2017.

10.

Endotypes of difficult-to-control asthma in inner-city African American children.

Brown KR, Krouse RZ, Calatroni A, Visness CM, Sivaprasad U, Kercsmar CM, Matsui EC, West JB, Makhija MM, Gill MA, Kim H, Kattan M, Pillai D, Gern JE, Busse WW, Togias A, Liu AH, Khurana Hershey GK.

PLoS One. 2017 Jul 7;12(7):e0180778. doi: 10.1371/journal.pone.0180778. eCollection 2017.

11.

Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence.

Heymann PW, Nguyen HT, Steinke JW, Turner RB, Woodfolk JA, Platts-Mills TAE, Martin L, He H, Biagini Myers J, Lindsey M, Sivaprasad U, Medvedovic M, Mahi N, Carper H, Murphy DD, Patrie J, Khurana Hershey GK.

PLoS One. 2017 May 26;12(5):e0178096. doi: 10.1371/journal.pone.0178096. eCollection 2017.

12.

KIF3A genetic variation is associated with pediatric asthma in the presence of eczema independent of allergic rhinitis.

Johansson E, Biagini Myers JM, Martin LJ, He H, Pilipenko V, Mersha T, Weirauch M, Salomonis N, Ryan P, LeMasters GK, Bernstein DI, Lockey J, Khurana Hershey GK.

J Allergy Clin Immunol. 2017 Aug;140(2):595-598.e5. doi: 10.1016/j.jaci.2017.02.003. Epub 2017 Feb 24. No abstract available.

PMID:
28238750
13.

Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index.

Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ.

J Allergy Clin Immunol. 2017 Oct;140(4):1130-1137.e5. doi: 10.1016/j.jaci.2017.01.026. Epub 2017 Feb 24.

PMID:
28238748
14.

Correction: IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.

Singh B, Jegga AG, Shanmukhappa KS, Edukulla R, Khurana Hershey GK, Medvedovic M, Dillon SR, Madala SK.

PLoS One. 2017 Jan 23;12(1):e0170446. doi: 10.1371/journal.pone.0170446. eCollection 2017.

15.

Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens.

Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA.

J Immunol. 2016 Dec 1;197(11):4228-4239. Epub 2016 Oct 28.

16.

Air pollution, epigenetics, and asthma.

Ji H, Biagini Myers JM, Brandt EB, Brokamp C, Ryan PH, Khurana Hershey GK.

Allergy Asthma Clin Immunol. 2016 Oct 19;12:51. eCollection 2016. Review.

17.

The nasal methylome and childhood atopic asthma.

Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA.

J Allergy Clin Immunol. 2017 May;139(5):1478-1488. doi: 10.1016/j.jaci.2016.07.036. Epub 2016 Oct 13.

18.

Pathways through which asthma risk factors contribute to asthma severity in inner-city children.

Liu AH, Babineau DC, Krouse RZ, Zoratti EM, Pongracic JA, O'Connor GT, Wood RA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Kattan M, Teach SJ, Makhija M, Pillai D, Lamm CI, Gern JE, Sigelman SM, Gergen PJ, Togias A, Visness CM, Busse WW.

J Allergy Clin Immunol. 2016 Oct;138(4):1042-1050. doi: 10.1016/j.jaci.2016.06.060.

19.

Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents.

Pongracic JA, Krouse RZ, Babineau DC, Zoratti EM, Cohen RT, Wood RA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Kattan M, Teach SJ, Johnson CC, Bacharier LB, Gern JE, Sigelman SM, Gergen PJ, Togias A, Visness CM, Busse WW, Liu AH.

J Allergy Clin Immunol. 2016 Oct;138(4):1030-1041. doi: 10.1016/j.jaci.2016.06.059.

20.

Asthma phenotypes in inner-city children.

Zoratti EM, Krouse RZ, Babineau DC, Pongracic JA, O'Connor GT, Wood RA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Kattan M, Teach SJ, Sigelman SM, Gergen PJ, Togias A, Visness CM, Busse WW, Liu AH.

J Allergy Clin Immunol. 2016 Oct;138(4):1016-1029. doi: 10.1016/j.jaci.2016.06.061.

21.

Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry.

Gupta J, Johansson E, Bernstein JA, Chakraborty R, Khurana Hershey GK, Rothenberg ME, Mersha TB.

J Allergy Clin Immunol. 2016 Sep;138(3):676-699. doi: 10.1016/j.jaci.2016.02.045. Epub 2016 Jun 11. Review.

22.

A combination of dexamethasone and anti-IL-17A treatment can alleviate diesel exhaust particle-induced steroid insensitive asthma.

Brandt EB, Khurana Hershey GK.

J Allergy Clin Immunol. 2016 Sep;138(3):924-928.e2. doi: 10.1016/j.jaci.2016.03.037. Epub 2016 May 5. No abstract available.

23.

β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses.

Zhang Z, Biagini Myers JM, Brandt EB, Ryan PH, Lindsey M, Mintz-Cole RA, Reponen T, Vesper SJ, Forde F, Ruff B, Bass SA, LeMasters GK, Bernstein DI, Lockey J, Budelsky AL, Khurana Hershey GK.

J Allergy Clin Immunol. 2017 Jan;139(1):54-65.e8. doi: 10.1016/j.jaci.2016.02.031. Epub 2016 Apr 20.

24.

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells.

Ulm A, Mayhew CN, Debley J, Khurana Hershey GK, Ji H.

J Vis Exp. 2016 Mar 10;(109). doi: 10.3791/53814.

25.

Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways.

Ghosh D, Ding L, Sivaprasad U, Geh E, Biagini Myers J, Bernstein JA, Khurana Hershey GK, Mersha TB.

PLoS One. 2015 Dec 30;10(12):e0144316. doi: 10.1371/journal.pone.0144316. eCollection 2015.

26.

Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution.

Somineni HK, Zhang X, Biagini Myers JM, Kovacic MB, Ulm A, Jurcak N, Ryan PH, Khurana Hershey GK, Ji H.

J Allergy Clin Immunol. 2016 Mar;137(3):797-805.e5. doi: 10.1016/j.jaci.2015.10.021. Epub 2015 Dec 10.

27.

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations.

Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ.

J Allergy Clin Immunol. 2015 Dec;136(6):1476-1485. doi: 10.1016/j.jaci.2015.09.008. Epub 2015 Oct 27.

28.

Timing and Duration of Traffic-related Air Pollution Exposure and the Risk for Childhood Wheeze and Asthma.

Brunst KJ, Ryan PH, Brokamp C, Bernstein D, Reponen T, Lockey J, Khurana Hershey GK, Levin L, Grinshpun SA, LeMasters G.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):421-7. doi: 10.1164/rccm.201407-1314OC.

29.

Genetic approach identifies distinct asthma pathways in overweight vs normal weight children.

Butsch Kovacic M, Martin LJ, Biagini Myers JM, He H, Lindsey M, Mersha TB, Khurana Hershey GK.

Allergy. 2015 Aug;70(8):1028-32. doi: 10.1111/all.12656. Epub 2015 Jun 8.

30.

Vanin-1 expression and methylation discriminate pediatric asthma corticosteroid treatment response.

Xiao C, Biagini Myers JM, Ji H, Metz K, Martin LJ, Lindsey M, He H, Powers R, Ulm A, Ruff B, Ericksen MB, Somineni HK, Simmons J, Strait RT, Kercsmar CM, Khurana Hershey GK.

J Allergy Clin Immunol. 2015 Oct;136(4):923-31.e3. doi: 10.1016/j.jaci.2015.01.045. Epub 2015 Apr 21.

31.

Genomic architecture of asthma differs by sex.

Mersha TB, Martin LJ, Biagini Myers JM, Kovacic MB, He H, Lindsey M, Sivaprasad U, Chen W, Khurana Hershey GK.

Genomics. 2015 Jul;106(1):15-22. doi: 10.1016/j.ygeno.2015.03.003. Epub 2015 Mar 25.

32.

Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility.

Brandt EB, Biagini Myers JM, Acciani TH, Ryan PH, Sivaprasad U, Ruff B, LeMasters GK, Bernstein DI, Lockey JE, LeCras TD, Khurana Hershey GK.

J Allergy Clin Immunol. 2015 Aug;136(2):295-303.e7. doi: 10.1016/j.jaci.2014.11.043. Epub 2015 Mar 4.

33.

Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of age.

Codispoti CD, Bernstein DI, Levin L, Reponen T, Ryan PH, Biagini Myers JM, Villareal M, Burkle J, Lummus Z, Lockey JE, Khurana Hershey GK, LeMasters GK.

Ann Allergy Asthma Immunol. 2015 Mar;114(3):193-198.e4. doi: 10.1016/j.anai.2014.12.008.

34.

Heterogeneity in asthma care in a statewide collaborative: the Ohio Pediatric Asthma Repository.

Biagini Myers JM, Simmons JM, Kercsmar CM, Martin LJ, Pilipenko VV, Austin SR, Lindsey MA, Amalfitano KM, Guilbert TW, McCoy KS, Forbis SG, McBride JT, Ross KR, Vauthy PA, Khurana Hershey GK.

Pediatrics. 2015 Feb;135(2):271-9. doi: 10.1542/peds.2014-2230. Epub 2015 Jan 19.

35.

Traffic pollution is associated with early childhood aeroallergen sensitization.

Codispoti CD, LeMasters GK, Levin L, Reponen T, Ryan PH, Biagini Myers JM, Villareal M, Burkle J, Evans S, Lockey JE, Khurana Hershey GK, Bernstein DI.

Ann Allergy Asthma Immunol. 2015 Feb;114(2):126-33. doi: 10.1016/j.anai.2014.10.020. Epub 2014 Dec 10.

36.

Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells.

Ji H, Zhang X, Oh S, Mayhew CN, Ulm A, Somineni HK, Ericksen M, Wells JM, Khurana Hershey GK.

J Allergy Clin Immunol. 2015 Jan;135(1):236-44. doi: 10.1016/j.jaci.2014.08.038. Epub 2014 Oct 14.

37.

Secondhand smoke and traffic exhaust confer opposing risks for asthma in normal and overweight children.

LeMasters G, Levin L, Bernstein DI, Lockey SD 4th, Lockey JE, Burkle J, Khurana Hershey GK, Brunst K, Ryan PH.

Obesity (Silver Spring). 2015 Jan;23(1):32-6. doi: 10.1002/oby.20941. Epub 2014 Nov 19.

38.

Duration of day care attendance during infancy predicts asthma at the age of seven: the Cincinnati Childhood Allergy and Air Pollution Study.

Cheng G, Smith AM, Levin L, Epstein T, Ryan PH, LeMasters GK, Khurana Hershey GK, Reponen T, Villareal M, Lockey J, Bernstein DI.

Clin Exp Allergy. 2014 Oct;44(10):1274-81. doi: 10.1111/cea.12397.

PMID:
25179746
39.

N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort.

LeMasters GK, Khurana Hershey GK, Sivaprasad U, Martin LJ, Pilipenko V, Ericksen MB, Burkle JW, Lindsey MA, Bernstein DI, Lockey JE, Gareri J, Lubetsky A, Koren G, Biagini Myers JM.

Pharmacogenomics J. 2015 Apr;15(2):189-95. doi: 10.1038/tpj.2014.44. Epub 2014 Aug 26.

40.

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

Sivaprasad U, Kinker KG, Ericksen MB, Lindsey M, Gibson AM, Bass SA, Hershey NS, Deng J, Medvedovic M, Khurana Hershey GK.

J Invest Dermatol. 2015 Jan;135(1):160-169. doi: 10.1038/jid.2014.353. Epub 2014 Aug 11.

41.

Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma.

Biagini Myers JM, Martin LJ, Kovacic MB, Mersha TB, He H, Pilipenko V, Lindsey MA, Ericksen MB, Bernstein DI, LeMasters GK, Lockey JE, Khurana Hershey GK.

J Allergy Clin Immunol. 2014 Oct;134(4):891-899.e3. doi: 10.1016/j.jaci.2014.03.037. Epub 2014 May 13.

42.

Reply: To PMID 24060272.

Brandt EB, Ryan PH, Khurana Hershey GK.

J Allergy Clin Immunol. 2014 May;133(5):1496-7. doi: 10.1016/j.jaci.2013.12.1097. Epub 2014 Mar 15. No abstract available.

PMID:
24636093
43.

EGFR signaling blunts allergen-induced IL-6 production and Th17 responses in the skin and attenuates development and relapse of atopic dermatitis.

Zhang Z, Xiao C, Gibson AM, Bass SA, Khurana Hershey GK.

J Immunol. 2014 Feb 1;192(3):859-66. doi: 10.4049/jimmunol.1301062. Epub 2013 Dec 13.

44.

Regulation of IL-4 receptor signaling by STUB1 in lung inflammation.

Wei Q, Sha Y, Bhattacharya A, Abdel Fattah E, Bonilla D, Jyothula SS, Pandit L, Khurana Hershey GK, Eissa NT.

Am J Respir Crit Care Med. 2014 Jan 1;189(1):16-29. doi: 10.1164/rccm.201305-0874OC.

45.

Diesel exhaust particle exposure increases severity of allergic asthma in young mice.

Acciani TH, Brandt EB, Khurana Hershey GK, Le Cras TD.

Clin Exp Allergy. 2013 Dec;43(12):1406-18. doi: 10.1111/cea.12200.

PMID:
24112543
46.

Diesel exhaust particle induction of IL-17A contributes to severe asthma.

Brandt EB, Kovacic MB, Lee GB, Gibson AM, Acciani TH, Le Cras TD, Ryan PH, Budelsky AL, Khurana Hershey GK.

J Allergy Clin Immunol. 2013 Nov;132(5):1194-1204.e2. doi: 10.1016/j.jaci.2013.06.048. Epub 2013 Sep 20.

47.

Exacerbation of allergen-induced eczema in TLR4- and TRIF-deficient mice.

Brandt EB, Gibson AM, Bass S, Rydyznski C, Khurana Hershey GK.

J Immunol. 2013 Oct 1;191(7):3519-25. doi: 10.4049/jimmunol.1300789. Epub 2013 Aug 30.

48.

Microbial content of household dust associated with exhaled NO in asthmatic children.

Johansson E, Reponen T, Vesper S, Levin L, Lockey J, Ryan P, Bernstein DI, Villareal M, Khurana Hershey GK, Schaffer C, Lemasters G.

Environ Int. 2013 Sep;59:141-7. doi: 10.1016/j.envint.2013.05.011. Epub 2013 Jun 24.

49.

IL-13 receptor α2 contributes to development of experimental allergic asthma.

Chen W, Sivaprasad U, Gibson AM, Ericksen MB, Cunningham CM, Bass SA, Kinker KG, Finkelman FD, Wills-Karp M, Khurana Hershey GK.

J Allergy Clin Immunol. 2013 Oct;132(4):951-8.e1-6. doi: 10.1016/j.jaci.2013.04.016. Epub 2013 Jun 12.

50.

Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma.

Lee GB, Brandt EB, Xiao C, Gibson AM, Le Cras TD, Brown LA, Fitzpatrick AM, Khurana Hershey GK.

PLoS One. 2013;8(3):e60632. doi: 10.1371/journal.pone.0060632. Epub 2013 Mar 29.

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