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IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer.

You R, DeMayo FJ, Liu J, Cho SN, Burt BM, Creighton CJ, Casal RF, Lazarus DR, Lu W, Tung HY, Yuan X, Hill-McALester A, Kim M, Perusich S, Cornwell L, Rosen D, Song LZ, Paust S, Diehl G, Corry D, Kheradmand F.

Cancer Immunol Res. 2018 Apr 13. doi: 10.1158/2326-6066.CIR-17-0554. [Epub ahead of print]


Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma.

Lee HS, Jang HJ, Choi JM, Zhang J, de Rosen VL, Wheeler TM, Lee JS, Tu T, Jindra PT, Kerman RH, Jung SY, Kheradmand F, Sugarbaker DJ, Burt BM.

JCI Insight. 2018 Apr 5;3(7). pii: 98575. doi: 10.1172/jci.insight.98575. [Epub ahead of print]


Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis.

Li E, Tsai CL, Maskatia ZK, Kakkar E, Porter P, Rossen RD, Perusich S, Knight JM, Kheradmand F, Corry DB.

Immun Inflamm Dis. 2018 Jun;6(2):264-275. doi: 10.1002/iid3.215. Epub 2018 Mar 25.


Matrix remodeling in chronic lung diseases.

Gu BH, Madison MC, Corry D, Kheradmand F.

Matrix Biol. 2018 Mar 17. pii: S0945-053X(17)30372-4. doi: 10.1016/j.matbio.2018.03.012. [Epub ahead of print] Review.


Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Mar 8. pii: S0945-053X(17)30434-1. doi: 10.1016/j.matbio.2018.03.005. [Epub ahead of print] Review.


Advances and Evolving Concepts in Allergic Asthma.

Tung HY, Li E, Landers C, Nguyen A, Kheradmand F, Knight JM, Corry DB.

Semin Respir Crit Care Med. 2018 Feb;39(1):64-81. doi: 10.1055/s-0037-1607981. Epub 2018 Feb 10.


AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity.

Liang D, Tian L, You R, Halpert MM, Konduri V, Baig YC, Paust S, Kim D, Kim S, Jia F, Huang S, Zhang X, Kheradmand F, Corry DB, Gilbert BE, Levitt JM, Decker WK.

Front Immunol. 2018 Jan 15;8:1801. doi: 10.3389/fimmu.2017.01801. eCollection 2017.


Chronic ethanol increases calcium/calmodulin-dependent protein kinaseIIδ gene expression and decreases monoamine oxidase amount in rat heart muscles: Rescue effect of Zingiber officinale (ginger) extract.

Heshmati E, Shirpoor A, Kheradmand F, Alizadeh M, Gharalari FH.

Anatol J Cardiol. 2018 Jan;19(1):19-26. doi: 10.14744/AnatolJCardiol.2017.8079.


Cytotoxic effects of the newly-developed chemotherapeutic agents 17-AAG in combination with oxaliplatin and capecitabine in colorectal cancer cell lines.

Mohammadian M, Zeynali S, Azarbaijani AF, Khadem Ansari MH, Kheradmand F.

Res Pharm Sci. 2017 Dec;12(6):517-525. doi: 10.4103/1735-5362.217432.


Nandrolone administration with or without strenuous exercise promotes overexpression of nephrin and podocin genes and induces structural and functional alterations in the kidneys of rats.

Tofighi A, Ahmadi S, Seyyedi SM, Shirpoor A, Kheradmand F, Gharalari FH.

Toxicol Lett. 2018 Jan 5;282:147-153. doi: 10.1016/j.toxlet.2017.10.015. Epub 2017 Oct 31.


Protective role of γδ T cells in cigarette smoke and influenza infection.

Hong MJ, Gu BH, Madison MC, Landers C, Tung HY, Kim M, Yuan X, You R, Machado AA, Gilbert BE, Soroosh P, Elloso M, Song L, Chen M, Corry DB, Diehl G, Kheradmand F.

Mucosal Immunol. 2017 Nov 1. doi: 10.1038/mi.2017.93. [Epub ahead of print]


Th17/Treg immunoregulation and implications in treatment of sulfur mustard gas-induced lung diseases.

Iman M, Rezaei R, Azimzadeh Jamalkandi S, Shariati P, Kheradmand F, Salimian J.

Expert Rev Clin Immunol. 2017 Dec;13(12):1173-1188. doi: 10.1080/1744666X.2017.1389646. Epub 2017 Oct 23.


Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.

Jin F, Thaiparambil J, Donepudi SR, Vantaku V, Piyarathna DWB, Maity S, Krishnapuram R, Putluri V, Gu F, Purwaha P, Bhowmik SK, Ambati CR, von Rundstedt FC, Roghmann F, Berg S, Noldus J, Rajapakshe K, Gödde D, Roth S, Störkel S, Degener S, Michailidis G, Kaipparettu BA, Karanam B, Terris MK, Kavuri SM, Lerner SP, Kheradmand F, Coarfa C, Sreekumar A, Lotan Y, El-Zein R, Putluri N.

Cancer Prev Res (Phila). 2017 Oct;10(10):588-597. doi: 10.1158/1940-6207.CAPR-17-0198. Epub 2017 Aug 29.


Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models.

Decker WK, da Silva RF, Sanabria MH, Angelo LS, Guimarães F, Burt BM, Kheradmand F, Paust S.

Front Immunol. 2017 Aug 2;8:829. doi: 10.3389/fimmu.2017.00829. eCollection 2017. Review.


Cigarette Smoke and DNA Cleavage Promote Lung Inflammation and Emphysema.

Kheradmand F, You R, Hee Gu B, Corry DB.

Trans Am Clin Climatol Assoc. 2017;128:222-233. Review.


The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs.

Hendrix AY, Kheradmand F.

Prog Mol Biol Transl Sci. 2017;148:1-29. doi: 10.1016/bs.pmbts.2017.04.004. Epub 2017 May 19. Review.


Ginger extract mitigates ethanol-induced changes of alpha and beta - myosin heavy chain isoforms gene expression and oxidative stress in the heart of male wistar rats.

Shirpoor A, Zerehpoosh M, Ansari MHK, Kheradmand F, Rasmi Y.

DNA Repair (Amst). 2017 Sep;57:45-49. doi: 10.1016/j.dnarep.2017.06.023. Epub 2017 Jun 21.


A Brief History of Cardiac Syndrome X: A Biochemical View.

Rasmi Y, Majidinia M, Khosravifar F, Kheradmand F.

J Tehran Heart Cent. 2017 Jan;12(1):46-48. No abstract available.


Imatinib and its combination with 2,5-dimethyl-celecoxibinduces apoptosis of human HT-29 colorectal cancer cells.

Atari-Hajipirloo S, Nikanfar S, Heydari A, Kheradmand F.

Res Pharm Sci. 2017 Feb;12(1):67-73. doi: 10.4103/1735-5362.199049.


Altered Concentrations of Copper, Zinc, and Iron are Associated With Increased Levels of Glycated Hemoglobin in Patients With Type 2 Diabetes Mellitus and Their First-Degree Relatives.

Atari-Hajipirloo S, Valizadeh N, Khadem-Ansari MH, Rasmi Y, Kheradmand F.

Int J Endocrinol Metab. 2016 Mar 19;14(2):e33273. eCollection 2016 Apr.


Imatinib alters cell viability but not growth factors levels in TM4 Sertoli cells.

Hashemnia SM, Atari-Hajipirloo S, Roshan-Milani S, Valizadeh N, Mahabadi S, Kheradmand F.

Int J Reprod Biomed (Yazd). 2016 Sep;14(9):577-582.


Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages.

Wang DH, Lee HS, Yoon D, Berry G, Wheeler TM, Sugarbaker DJ, Kheradmand F, Engleman E, Burt BM.

Clin Cancer Res. 2017 Feb 1;23(3):778-788. doi: 10.1158/1078-0432.CCR-15-2597. Epub 2016 Aug 5.


Zinc attenuates ethanol-induced Sertoli cell toxicity and apoptosis through caspase-3 mediated pathways.

Pourhassanali N, Roshan-Milani S, Kheradmand F, Motazakker M, Bagheri M, Saboory E.

Reprod Toxicol. 2016 Jun;61:97-103. doi: 10.1016/j.reprotox.2016.03.041. Epub 2016 Mar 23.


The effect of celecoxib and its combination with imatinib on human HT-29 colorectal cancer cells: Involvement of COX-2, Caspase-3, VEGF and NF-κB genes expression.

Atari-Hajipirloo S, Nikanfar S, Heydari A, Noori F, Kheradmand F.

Cell Mol Biol (Noisy-le-grand). 2016 Feb 29;62(2):68-74.


Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer.

Liu Y, Kheradmand F, Davis CF, Scheurer ME, Wheeler D, Tsavachidis S, Armstrong G, Simpson C, Mandal D, Kupert E, Anderson M, You M, Xiong D, Pikielny C, Schwartz AG, Bailey-Wilson J, Gaba C, De Andrade M, Yang P, Pinney SM; Genetic Epidemiology of Lung Cancer Consortium, Amos CI, Spitz MR.

J Thorac Oncol. 2016 Jan;11(1):52-61. doi: 10.1016/j.jtho.2015.09.015.


Allergen-encoded signals that control allergic responses.

Tung HY, Landers C, Li E, Porter P, Kheradmand F, Corry DB.

Curr Opin Allergy Clin Immunol. 2016 Feb;16(1):51-8. doi: 10.1097/ACI.0000000000000233. Review.


Long-Acting Beta Agonists Enhance Allergic Airway Disease.

Knight JM, Mak G, Shaw J, Porter P, McDermott C, Roberts L, You R, Yuan X, Millien VO, Qian Y, Song LZ, Frazier V, Kim C, Kim JJ, Bond RA, Milner JD, Zhang Y, Mandal PK, Luong A, Kheradmand F, McMurray JS, Corry DB.

PLoS One. 2015 Nov 25;10(11):e0142212. doi: 10.1371/journal.pone.0142212. eCollection 2015.


Loss of Peripheral Tolerance in Emphysema. Phenotypes, Exacerbations, and Disease Progression.

Bhavani S, Yuan X, You R, Shan M, Corry D, Kheradmand F.

Ann Am Thorac Soc. 2015 Nov;12 Suppl 2:S164-8. doi: 10.1513/AnnalsATS.201503-115AW.


Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema.

You R, Lu W, Shan M, Berlin JM, Samuel EL, Marcano DC, Sun Z, Sikkema WK, Yuan X, Song L, Hendrix AY, Tour JM, Corry DB, Kheradmand F.

Elife. 2015 Oct 5;4:e09623. doi: 10.7554/eLife.09623.


The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema.

Lu W, You R, Yuan X, Yang T, Samuel EL, Marcano DC, Sikkema WK, Tour JM, Rodriguez A, Kheradmand F, Corry DB.

Nat Immunol. 2015 Nov;16(11):1185-94. doi: 10.1038/ni.3292. Epub 2015 Oct 5.


Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD).

Bhavani S, Tsai CL, Perusich S, Hesselbacher S, Coxson H, Pandit L, Corry DB, Kheradmand F.

Am J Respir Crit Care Med. 2015 Nov 15;192(10):1171-8. doi: 10.1164/rccm.201504-0736OC.


Reply: Is Endobronchial Ultrasound Influenced by Sedation Strategy? Comparing Apples to Apples.

Casal RF, Nogueras-González G, Kheradmand F.

Am J Respir Crit Care Med. 2015 Jun 15;191(12):1470-1. doi: 10.1164/rccm.201503-0650LE. No abstract available.


Erratum: Bioactive Lipids in Emphysema: Decoding Fat to Reveal COPD Phenotypes.

Mirzaie M, Kheradmand F.

Am J Respir Crit Care Med. 2015 May 15;191(10):1210. doi: 10.1164/rccm.19110erratum1. No abstract available.


Oxidative stress response in patients infected by diverse hepatitis C virus genotypes.

Khadem Ansari MH, Omrani MD, Kheradmand F.

Hepat Mon. 2015 Feb 21;15(2):e22069. doi: 10.5812/hepatmon.22069. eCollection 2015 Feb.


ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.

Liu J, Cho SN, Akkanti B, Jin N, Mao J, Long W, Chen T, Zhang Y, Tang X, Wistub II, Creighton CJ, Kheradmand F, DeMayo FJ.

Cell Rep. 2015 Mar 3. pii: S2211-1247(15)00142-4. doi: 10.1016/j.celrep.2015.02.014. [Epub ahead of print]


Bioactive lipids in emphysema. Decoding fat to reveal COPD phenotypes.

Mirzaie M, Kheradmand F.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):241-3. doi: 10.1164/rccm.201412-2264ED. No abstract available. Erratum in: Am J Respir Crit Care Med. 2015 May 15;191(10):1210.


Randomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation.

Casal RF, Lazarus DR, Kuhl K, Nogueras-González G, Perusich S, Green LK, Ost DE, Sarkiss M, Jimenez CA, Eapen GA, Morice RC, Cornwell L, Austria S, Sharafkanneh A, Rumbaut RE, Grosu H, Kheradmand F.

Am J Respir Crit Care Med. 2015 Apr 1;191(7):796-803. doi: 10.1164/rccm.201409-1615OC.


Airway fibrinogenolysis and the initiation of allergic inflammation.

Millien VO, Lu W, Mak G, Yuan X, Knight JM, Porter P, Kheradmand F, Corry DB.

Ann Am Thorac Soc. 2014 Dec;11 Suppl 5:S277-83. doi: 10.1513/AnnalsATS.201403-105AW. Review.


Activation of C3a receptor is required in cigarette smoke-mediated emphysema.

Yuan X, Shan M, You R, Frazier MV, Hong MJ, Wetsel RA, Drouin S, Seryshev A, Song LZ, Cornwell L, Rossen RD, Corry DB, Kheradmand F.

Mucosal Immunol. 2015 Jul;8(4):874-85. doi: 10.1038/mi.2014.118. Epub 2014 Dec 3.


The effects of propofol-midazolam-ketamine co-induction on hemodynamic changes and catecholamine response.

Abbasivash R, Aghdashi MM, Sinaei B, Kheradmand F.

J Clin Anesth. 2014 Dec;26(8):628-33. doi: 10.1016/j.jclinane.2014.05.014. Epub 2014 Oct 18.


Leukotriene A4 hydrolase: the Janus enzyme shows its ugly side in smokers.

Snelgrove R, Kheradmand F.

Am J Respir Crit Care Med. 2014 Jul 1;190(1):5-7. doi: 10.1164/rccm.201405-0975ED. No abstract available.


Airway surface mycosis in chronic TH2-associated airway disease.

Porter PC, Lim DJ, Maskatia ZK, Mak G, Tsai CL, Citardi MJ, Fakhri S, Shaw JL, Fothergil A, Kheradmand F, Corry DB, Luong A.

J Allergy Clin Immunol. 2014 Aug;134(2):325-31. doi: 10.1016/j.jaci.2014.04.028. Epub 2014 Jun 11.


Leukotriene enhanced allergic lung inflammation through induction of chemokine production.

Shin K, Hwang JJ, Kwon BI, Kheradmand F, Corry DB, Lee SH.

Clin Exp Med. 2015 Aug;15(3):233-44. doi: 10.1007/s10238-014-0292-7. Epub 2014 Jun 13.


Essential role for autophagy in the maintenance of immunological memory against influenza infection.

Chen M, Hong MJ, Sun H, Wang L, Shi X, Gilbert BE, Corry DB, Kheradmand F, Wang J.

Nat Med. 2014 May;20(5):503-10. doi: 10.1038/nm.3521. Epub 2014 Apr 20.


Predictors of 10-year pancreas allograft survival after simultaneous pancreas and kidney transplantation.

Davis NF, Burke JP, Kelly R, Shields WP, Kheradmand F, Zimmermann A, Mohan P, Hickey DP.

Pancreas. 2014 Jul;43(5):750-4. doi: 10.1097/MPA.0000000000000119.


Zinc and low-dose of cadmium protect sertoli cells against toxic-dose of cadmium: The role of metallothionein.

Kheradmand F, Nourmohammadi I, Ahmadi-Faghih MA, Firoozrai M, Modarressi MH.

Iran J Reprod Med. 2013 Jun;11(6):487-94.


Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.

Shan M, You R, Yuan X, Frazier MV, Porter P, Seryshev A, Hong JS, Song LZ, Zhang Y, Hilsenbeck S, Whitehead L, Zarinkamar N, Perusich S, Corry DB, Kheradmand F.

J Clin Invest. 2014 Mar;124(3):1371-81. doi: 10.1172/JCI70587. Epub 2014 Feb 24.


Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4.

Millien VO, Lu W, Shaw J, Yuan X, Mak G, Roberts L, Song LZ, Knight JM, Creighton CJ, Luong A, Kheradmand F, Corry DB.

Science. 2013 Aug 16;341(6147):792-6. doi: 10.1126/science.1240342.


IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps.

Shaw JL, Fakhri S, Citardi MJ, Porter PC, Corry DB, Kheradmand F, Liu YJ, Luong A.

Am J Respir Crit Care Med. 2013 Aug 15;188(4):432-9. doi: 10.1164/rccm.201212-2227OC.

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