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Items: 38


Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction.

Ghosh M, Thangada S, Dasgupta O, Khanna KM, Yamase HT, Kashgarian M, Hla T, Shapiro LH, Ferrer FA.

PLoS One. 2018 Mar 8;13(3):e0194053. doi: 10.1371/journal.pone.0194053. eCollection 2018.


Combining Adoptive Cell Therapy with Cytomegalovirus-Based Vaccine Is Protective against Solid Skin Tumors.

Grenier JM, Yeung ST, Qiu Z, Jellison ER, Khanna KM.

Front Immunol. 2018 Jan 16;8:1993. doi: 10.3389/fimmu.2017.01993. eCollection 2017.


Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis.

Huang K, Mukherjee S, DesMarais V, Albanese JM, Rafti E, Draghi A, Maher LA, Khanna KM, Mani S, Matson AP.

Pediatr Res. 2018 Jan 23. doi: 10.1038/pr.2018.14. [Epub ahead of print]


CD169+ macrophages orchestrate innate immune responses by regulating bacterial localization in the spleen.

Perez OA, Yeung ST, Vera-Licona P, Romagnoli PA, Samji T, Ural BB, Maher L, Tanaka M, Khanna KM.

Sci Immunol. 2017 Oct 6;2(16). pii: eaah5520. doi: 10.1126/sciimmunol.aah5520.


Visualizing Endogenous Effector T Cell Egress from the Lymph Nodes.

Menon M, Benechet AP, Khanna KM.

Methods Mol Biol. 2017;1591:59-71. doi: 10.1007/978-1-4939-6931-9_5.


Corrigendum: Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4.

Qiu Z, Cervantes JL, Cicek BB, Mukherjee S, Venkatesh M, Maher LA, Salazar JC, Mani S, Khanna KM.

Sci Rep. 2017 Mar 22;7:44959. doi: 10.1038/srep44959. No abstract available.


Understanding memory CD8+ T cells.

Samji T, Khanna KM.

Immunol Lett. 2017 May;185:32-39. doi: 10.1016/j.imlet.2017.02.012. Epub 2017 Mar 6. Review.


Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4.

Qiu Z, Cervantes JL, Cicek BB, Mukherjee S, Venkatesh M, Maher LA, Salazar JC, Mani S, Khanna KM.

Sci Rep. 2016 Aug 23;6:31936. doi: 10.1038/srep31936.


Differentiation of distinct long-lived memory CD4 T cells in intestinal tissues after oral Listeria monocytogenes infection.

Romagnoli PA, Fu HH, Qiu Z, Khairallah C, Pham QM, Puddington L, Khanna KM, Lefrançois L, Sheridan BS.

Mucosal Immunol. 2017 Mar;10(2):520-530. doi: 10.1038/mi.2016.66. Epub 2016 Jul 27.


IL-17A-producing resident memory γδ T cells orchestrate the innate immune response to secondary oral Listeria monocytogenes infection.

Romagnoli PA, Sheridan BS, Pham QM, Lefrançois L, Khanna KM.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8502-7. doi: 10.1073/pnas.1600713113. Epub 2016 Jul 11.


TNF and CD28 Signaling Play Unique but Complementary Roles in the Systemic Recruitment of Innate Immune Cells after Staphylococcus aureus Enterotoxin A Inhalation.

Svedova J, Tsurutani N, Liu W, Khanna KM, Vella AT.

J Immunol. 2016 Jun 1;196(11):4510-21. doi: 10.4049/jimmunol.1600113. Epub 2016 Apr 20.


Reviving virus based cancer vaccines by using cytomegalovirus vectors expressing modified tumor antigens.

Qiu Z, Grenier JM, Khanna KM.

Oncoimmunology. 2015 Jun 5;5(1):e1056974. eCollection 2016.


T cell-intrinsic S1PR1 regulates endogenous effector T-cell egress dynamics from lymph nodes during infection.

Benechet AP, Menon M, Xu D, Samji T, Maher L, Murooka TT, Mempel TR, Sheridan BS, Lemoine FM, Khanna KM.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2182-7. doi: 10.1073/pnas.1516485113. Epub 2016 Feb 9.


Early Effector CD8 T Cells Display Plasticity in Populating the Short-Lived Effector and Memory-Precursor Pools Following Bacterial or Viral Infection.

Plumlee CR, Obar JJ, Colpitts SL, Jellison ER, Haining WN, Lefrancois L, Khanna KM.

Sci Rep. 2015 Jul 20;5:12264. doi: 10.1038/srep12264.


Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease.

Hill TM, Gilchuk P, Cicek BB, Osina MA, Boyd KL, Durrant DM, Metzger DW, Khanna KM, Joyce S.

PLoS Pathog. 2015 Jun 11;11(6):e1004975. doi: 10.1371/journal.ppat.1004975. eCollection 2015 Jun.


Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720.

Fujiwara M, Anstadt EJ, Khanna KM, Clark RB.

Clin Immunol. 2015 May;158(1):103-13. doi: 10.1016/j.clim.2015.03.018. Epub 2015 Mar 28.


Cytomegalovirus-Based Vaccine Expressing a Modified Tumor Antigen Induces Potent Tumor-Specific CD8(+) T-cell Response and Protects Mice from Melanoma.

Qiu Z, Huang H, Grenier JM, Perez OA, Smilowitz HM, Adler B, Khanna KM.

Cancer Immunol Res. 2015 May;3(5):536-46. doi: 10.1158/2326-6066.CIR-14-0044. Epub 2015 Jan 29.


Visualizing T Cell Migration in situ.

Benechet AP, Menon M, Khanna KM.

Front Immunol. 2014 Jul 29;5:363. doi: 10.3389/fimmu.2014.00363. eCollection 2014. Review.


Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

Venkatesh M, Mukherjee S, Wang H, Li H, Sun K, Benechet AP, Qiu Z, Maher L, Redinbo MR, Phillips RS, Fleet JC, Kortagere S, Mukherjee P, Fasano A, Le Ven J, Nicholson JK, Dumas ME, Khanna KM, Mani S.

Immunity. 2014 Aug 21;41(2):296-310. doi: 10.1016/j.immuni.2014.06.014. Epub 2014 Jul 24.


B cells, not just for antibody anymore.

Khanna KM, Lefrançois L.

Immunity. 2012 Mar 23;36(3):315-7. doi: 10.1016/j.immuni.2012.02.011.


Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.

Thangada S, Khanna KM, Blaho VA, Oo ML, Im DS, Guo C, Lefrancois L, Hla T.

J Exp Med. 2010 Jul 5;207(7):1475-83. doi: 10.1084/jem.20091343. Epub 2010 Jun 28.


T cell and APC dynamics in situ control the outcome of vaccination.

Khanna KM, Blair DA, Vella AT, McSorley SJ, Datta SK, Lefrançois L.

J Immunol. 2010 Jul 1;185(1):239-52. doi: 10.4049/jimmunol.0901047. Epub 2010 Jun 7.


In situ imaging reveals different responses by naïve and memory CD8 T cells to late antigen presentation by lymph node DC after influenza virus infection.

Khanna KM, Aguila CC, Redman JM, Suarez-Ramirez JE, Lefrançois L, Cauley LS.

Eur J Immunol. 2008 Dec;38(12):3304-15. doi: 10.1002/eji.200838602.


Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency.

Knickelbein JE, Khanna KM, Yee MB, Baty CJ, Kinchington PR, Hendricks RL.

Science. 2008 Oct 10;322(5899):268-71. doi: 10.1126/science.1164164.


Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection.

Obar JJ, Khanna KM, Lefrançois L.

Immunity. 2008 Jun;28(6):859-69. doi: 10.1016/j.immuni.2008.04.010. Epub 2008 May 22.


Geography and plumbing control the T cell response to infection.

Khanna KM, Lefrançois L.

Immunol Cell Biol. 2008 Jul;86(5):416-22. doi: 10.1038/icb.2008.22. Epub 2008 Apr 8. Review.


In situ imaging of the endogenous CD8 T cell response to infection.

Khanna KM, McNamara JT, Lefrançois L.

Science. 2007 Oct 5;318(5847):116-20.


Persistent antigen presentation after acute vesicular stomatitis virus infection.

Turner DL, Cauley LS, Khanna KM, Lefrançois L.

J Virol. 2007 Feb;81(4):2039-46. Epub 2006 Dec 6.


Latent virus influences the generation and maintenance of CD8+ T cell memory.

Sheridan BS, Khanna KM, Frank GM, Hendricks RL.

J Immunol. 2006 Dec 15;177(12):8356-64.


Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathway.

Cose S, Brammer C, Khanna KM, Masopust D, Lefrançois L.

Eur J Immunol. 2006 Jun;36(6):1423-33.


Sensory neurons regulate the effector functions of CD8+ T cells in controlling HSV-1 latency ex vivo.

Prabhakaran K, Sheridan BS, Kinchington PR, Khanna KM, Decman V, Lathrop K, Hendricks RL.

Immunity. 2005 Nov;23(5):515-25. Retraction in: Immunity. 2006 May;24(5):657.


Immune control of herpes simplex virus during latency.

Khanna KM, Lepisto AJ, Decman V, Hendricks RL.

Curr Opin Immunol. 2004 Aug;16(4):463-9. Review.


Immunity to latent viral infection: many skirmishes but few fatalities.

Khanna KM, Lepisto AJ, Hendricks RL.

Trends Immunol. 2004 May;25(5):230-4. Review. No abstract available.


Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons.

Liu T, Khanna KM, Carriere BN, Hendricks RL.

J Virol. 2001 Nov;75(22):11178-84.


CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons.

Liu T, Khanna KM, Chen X, Fink DJ, Hendricks RL.

J Exp Med. 2000 May 1;191(9):1459-66.

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