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Items: 1 to 50 of 145

1.

Mitochondrial tyrosyl-DNA phosphodiesterase 2 and its TDP2S short isoform.

Huang SN, Dalla Rosa I, Michaels SA, Tulumello DV, Agama K, Khiati S, Jean SR, Baechler SA, Factor VM, Varma S, Murai J, Miller Jenkins LM, Kelley SO, Pommier Y.

EMBO Rep. 2018 Feb 9. pii: e42139. doi: 10.15252/embr.201642139. [Epub ahead of print]

PMID:
29438979
2.

Synthetic Control over Quantum Well Width Distribution and Carrier Migration in Low-Dimensional Perovskite Photovoltaics.

Proppe AH, Quintero-Bermudez R, Tan H, Voznyy O, Kelley SO, Sargent EH.

J Am Chem Soc. 2018 Feb 16. doi: 10.1021/jacs.7b12551. [Epub ahead of print]

PMID:
29397693
3.

Combinatorial Probes for High-Throughput Electrochemical Analysis of Circulating Nucleic Acids in Patient Samples.

Kelley SO, Das J, Ivanov I, Safaei T, Sargent E.

Angew Chem Int Ed Engl. 2018 Feb 1. doi: 10.1002/anie.201800455. [Epub ahead of print]

PMID:
29389071
4.

Mixed-quantum-dot solar cells.

Yang Z, Fan JZ, Proppe AH, Arquer FPG, Rossouw D, Voznyy O, Lan X, Liu M, Walters G, Quintero-Bermudez R, Sun B, Hoogland S, Botton GA, Kelley SO, Sargent EH.

Nat Commun. 2017 Nov 6;8(1):1325. doi: 10.1038/s41467-017-01362-1.

5.

Characterization of Trypanosoma cruzi MutY DNA glycosylase ortholog and its role in oxidative stress response.

Kunrath-Lima M, Repolês BM, Alves CL, Furtado C, Rajão MA, Macedo AM, Franco GR, Pena SDJ, Valenzuela L, Wisnovsky S, Kelley SO, Galanti N, Cabrera G, Machado CR.

Infect Genet Evol. 2017 Nov;55:332-342. doi: 10.1016/j.meegid.2017.09.030. Epub 2017 Sep 29.

PMID:
28970112
6.

Advancing Ultrasensitive Molecular and Cellular Analysis Methods to Speed and Simplify the Diagnosis of Disease.

Kelley SO.

Acc Chem Res. 2017 Mar 21;50(3):503-507. doi: 10.1021/acs.accounts.6b00497.

PMID:
28945395
7.

Multifunctional quantum dot DNA hydrogels.

Zhang L, Jean SR, Ahmed S, Aldridge PM, Li X, Fan F, Sargent EH, Kelley SO.

Nat Commun. 2017 Aug 29;8(1):381. doi: 10.1038/s41467-017-00298-w.

8.

Biomolecular Steric Hindrance Effects Are Enhanced on Nanostructured Microelectrodes.

Mahshid SS, Vallée-Bélisle A, Kelley SO.

Anal Chem. 2017 Sep 19;89(18):9751-9757. doi: 10.1021/acs.analchem.7b01595. Epub 2017 Sep 5.

PMID:
28829912
9.

Enhancing the Potency of Nalidixic Acid toward a Bacterial DNA Gyrase with Conjugated Peptides.

Ahmed M, Kelley SO.

ACS Chem Biol. 2017 Oct 20;12(10):2563-2569. doi: 10.1021/acschembio.7b00540. Epub 2017 Sep 1.

PMID:
28825963
10.

Biexciton Resonances Reveal Exciton Localization in Stacked Perovskite Quantum Wells.

Elkins MH, Pensack R, Proppe AH, Voznyy O, Quan LN, Kelley SO, Sargent EH, Scholes GD.

J Phys Chem Lett. 2017 Aug 17;8(16):3895-3901. doi: 10.1021/acs.jpclett.7b01621. Epub 2017 Aug 7.

PMID:
28767258
11.

Steric Hindrance Assay for Secreted Factors in Stem Cell Culture.

Zhou W, Mahshid SS, Wang W, Vallée-Bélisle A, Zandstra PW, Sargent EH, Kelley SO.

ACS Sens. 2017 Apr 28;2(4):495-500. doi: 10.1021/acssensors.7b00136. Epub 2017 Apr 17.

PMID:
28723184
12.

What Are Clinically Relevant Levels of Cellular and Biomolecular Analytes?

Kelley SO.

ACS Sens. 2017 Feb 24;2(2):193-197. doi: 10.1021/acssensors.6b00691. Epub 2017 Jan 19.

PMID:
28723142
13.

Electrochemical DNA-Based Immunoassay That Employs Steric Hindrance To Detect Small Molecules Directly in Whole Blood.

Mahshid SS, Ricci F, Kelley SO, Vallée-Bélisle A.

ACS Sens. 2017 Jun 23;2(6):718-723. doi: 10.1021/acssensors.7b00176. Epub 2017 May 25.

PMID:
28723122
14.

Amplified Micromagnetic Field Gradients Enable High-Resolution Profiling of Rare Cell Subpopulations.

Poudineh M, Sargent EH, Kelley SO.

ACS Appl Mater Interfaces. 2017 Aug 9;9(31):25683-25690. doi: 10.1021/acsami.7b04677. Epub 2017 Jul 27.

PMID:
28696666
15.

Delivery and Release of Small-Molecule Probes in Mitochondria Using Traceless Linkers.

Lei EK, Kelley SO.

J Am Chem Soc. 2017 Jul 19;139(28):9455-9458. doi: 10.1021/jacs.7b04415. Epub 2017 Jul 5.

PMID:
28664723
16.

Isolation of Phenotypically Distinct Cancer Cells Using Nanoparticle-Mediated Sorting.

Green BJ, Kermanshah L, Labib M, Ahmed SU, Silva PN, Mahmoudian L, Chang IH, Mohamadi RM, Rocheleau JV, Kelley SO.

ACS Appl Mater Interfaces. 2017 Jun 21;9(24):20435-20443. doi: 10.1021/acsami.7b05253. Epub 2017 Jun 7.

PMID:
28548481
17.

Power-free, digital and programmable dispensing of picoliter droplets using a Digit Chip.

Mepham A, Besant JD, Weinstein AW, Burgess IB, Sargent EH, Kelley SO.

Lab Chip. 2017 Apr 11;17(8):1505-1514. doi: 10.1039/c7lc00199a.

PMID:
28350406
18.

Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron.

Alta RY, Vitorino HA, Goswami D, Liria CW, Wisnovsky SP, Kelley SO, Machini MT, Espósito BP.

PLoS One. 2017 Feb 8;12(2):e0171729. doi: 10.1371/journal.pone.0171729. eCollection 2017.

19.

Broadband Epsilon-near-Zero Reflectors Enhance the Quantum Efficiency of Thin Solar Cells at Visible and Infrared Wavelengths.

Labelle AJ, Bonifazi M, Tian Y, Wong C, Hoogland S, Favraud G, Walters G, Sutherland B, Liu M, Li J, Zhang X, Kelley SO, Sargent EH, Fratalocchi A.

ACS Appl Mater Interfaces. 2017 Feb 15;9(6):5556-5565. doi: 10.1021/acsami.6b13713. Epub 2017 Feb 3.

PMID:
28156089
20.

High-Curvature Nanostructuring Enhances Probe Display for Biomolecular Detection.

De Luna P, Mahshid SS, Das J, Luan B, Sargent EH, Kelley SO, Zhou R.

Nano Lett. 2017 Feb 8;17(2):1289-1295. doi: 10.1021/acs.nanolett.6b05153. Epub 2017 Jan 13.

PMID:
28075594
21.

Chemistry-Driven Approaches for Ultrasensitive Nucleic Acid Detection.

Smith SJ, Nemr CR, Kelley SO.

J Am Chem Soc. 2017 Jan 25;139(3):1020-1028. doi: 10.1021/jacs.6b10850. Epub 2017 Jan 9.

PMID:
28002665
22.

Profiling Functional and Biochemical Phenotypes of Circulating Tumor Cells Using a Two-Dimensional Sorting Device.

Poudineh M, Labib M, Ahmed S, Nguyen LN, Kermanshah L, Mohamadi RM, Sargent EH, Kelley SO.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):163-168. doi: 10.1002/anie.201608983. Epub 2016 Nov 29.

PMID:
27897359
23.

New Technologies for Rapid Bacterial Identification and Antibiotic Resistance Profiling.

Kelley SO.

SLAS Technol. 2017 Apr;22(2):113-121. doi: 10.1177/2211068216680207. Epub 2016 Nov 23.

PMID:
27879409
24.

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking.

Poudineh M, Aldridge PM, Ahmed S, Green BJ, Kermanshah L, Nguyen V, Tu C, Mohamadi RM, Nam RK, Hansen A, Sridhar SS, Finelli A, Fleshner NE, Joshua AM, Sargent EH, Kelley SO.

Nat Nanotechnol. 2017 Mar;12(3):274-281. doi: 10.1038/nnano.2016.239. Epub 2016 Nov 21.

PMID:
27870841
25.

Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma.

Buondonno I, Gazzano E, Jean SR, Audrito V, Kopecka J, Fanelli M, Salaroglio IC, Costamagna C, Roato I, Mungo E, Hattinger CM, Deaglio S, Kelley SO, Serra M, Riganti C.

Mol Cancer Ther. 2016 Nov;15(11):2640-2652. Epub 2016 Jul 27.

26.

High-Density Nanosharp Microstructures Enable Efficient CO2 Electroreduction.

Saberi Safaei T, Mepham A, Zheng X, Pang Y, Dinh CT, Liu M, Sinton D, Kelley SO, Sargent EH.

Nano Lett. 2016 Nov 9;16(11):7224-7228. Epub 2016 Oct 17.

PMID:
27736080
27.

Peptide Targeting of an Antibiotic Prodrug toward Phagosome-Entrapped Mycobacteria.

Pereira MP, Shi J, Kelley SO.

ACS Infect Dis. 2015 Dec 11;1(12):586-92. doi: 10.1021/acsinfecdis.5b00099. Epub 2015 Oct 21.

PMID:
27623056
28.

Circulating Tumor Cells (CTC) and Cell-Free DNA (cfDNA) Workshop 2016: Scientific Opportunities and Logistics for Cancer Clinical Trial Incorporation.

Lowes LE, Bratman SV, Dittamore R, Done S, Kelley SO, Mai S, Morin RD, Wyatt AW, Allan AL.

Int J Mol Sci. 2016 Sep 8;17(9). pii: E1505. doi: 10.3390/ijms17091505.

29.

Peptide-Mediated Delivery of Chemical Probes and Therapeutics to Mitochondria.

Jean SR, Ahmed M, Lei EK, Wisnovsky SP, Kelley SO.

Acc Chem Res. 2016 Sep 20;49(9):1893-902. doi: 10.1021/acs.accounts.6b00277. Epub 2016 Aug 16.

PMID:
27529125
30.

DNA Clutch Probes for Circulating Tumor DNA Analysis.

Das J, Ivanov I, Sargent EH, Kelley SO.

J Am Chem Soc. 2016 Aug 31;138(34):11009-16. doi: 10.1021/jacs.6b05679. Epub 2016 Aug 19.

PMID:
27513828
31.

Enhanced electrocatalytic CO2 reduction via field-induced reagent concentration.

Liu M, Pang Y, Zhang B, De Luna P, Voznyy O, Xu J, Zheng X, Dinh CT, Fan F, Cao C, de Arquer FP, Safaei TS, Mepham A, Klinkova A, Kumacheva E, Filleter T, Sinton D, Kelley SO, Sargent EH.

Nature. 2016 Sep 15;537(7620):382-386. doi: 10.1038/nature19060. Epub 2016 Aug 3.

PMID:
27487220
32.

Mitochondrial Chemical Biology: New Probes Elucidate the Secrets of the Powerhouse of the Cell.

Wisnovsky S, Lei EK, Jean SR, Kelley SO.

Cell Chem Biol. 2016 Aug 18;23(8):917-27. doi: 10.1016/j.chembiol.2016.06.012. Epub 2016 Jul 28. Review.

33.

Electrochemical Methods for the Analysis of Clinically Relevant Biomolecules.

Labib M, Sargent EH, Kelley SO.

Chem Rev. 2016 Aug 24;116(16):9001-90. doi: 10.1021/acs.chemrev.6b00220. Epub 2016 Jul 18. Review.

PMID:
27428515
34.

Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes.

Wisnovsky S, Jean SR, Kelley SO.

Nat Chem Biol. 2016 Jul;12(7):567-73. doi: 10.1038/nchembio.2102. Epub 2016 May 30.

PMID:
27239789
35.

Image-Reversal Soft Lithography: Fabrication of Ultrasensitive Biomolecular Detectors.

Safaei TS, Das J, Mahshid SS, Aldridge PM, Sargent EH, Kelley SO.

Adv Healthc Mater. 2016 Apr 20;5(8):893-9. doi: 10.1002/adhm.201501025. Epub 2016 Feb 10.

PMID:
26865322
36.

Aptamer and Antisense-Mediated Two-Dimensional Isolation of Specific Cancer Cell Subpopulations.

Labib M, Green B, Mohamadi RM, Mepham A, Ahmed SU, Mahmoudian L, Chang IH, Sargent EH, Kelley SO.

J Am Chem Soc. 2016 Mar 2;138(8):2476-9. doi: 10.1021/jacs.5b10939. Epub 2016 Feb 22.

PMID:
26860321
37.

Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles.

Zhou YG, Mohamadi RM, Poudineh M, Kermanshah L, Ahmed S, Safaei TS, Stojcic J, Nam RK, Sargent EH, Kelley SO.

Small. 2016 Feb 10;12(6):727-32. doi: 10.1002/smll.201502365. Epub 2015 Dec 28.

PMID:
26707703
38.

Beyond the Capture of Circulating Tumor Cells: Next-Generation Devices and Materials.

Green BJ, Saberi Safaei T, Mepham A, Labib M, Mohamadi RM, Kelley SO.

Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1252-65. doi: 10.1002/anie.201505100. Epub 2015 Dec 8. Review.

PMID:
26643151
39.

DISEASE DETECTOR.

Kelley SO.

Sci Am. 2015 Nov;313(5):48-51. No abstract available.

PMID:
26638399
40.

Fractal circuit sensors enable rapid quantification of biomarkers for donor lung assessment for transplantation.

Sage AT, Besant JD, Mahmoudian L, Poudineh M, Bai X, Zamel R, Hsin M, Sargent EH, Cypel M, Liu M, Keshavjee S, Kelley SO.

Sci Adv. 2015 Aug 28;1(7):e1500417. doi: 10.1126/sciadv.1500417. eCollection 2015 Aug.

41.

Using the inherent chemistry of the endothelin-1 peptide to develop a rapid assay for pre-transplant donor lung assessment.

Sage AT, Bai X, Cypel M, Liu M, Keshavjee S, Kelley SO.

Analyst. 2015 Dec 21;140(24):8092-6. doi: 10.1039/c5an01536g.

PMID:
26548776
42.

A digital microfluidic device with integrated nanostructured microelectrodes for electrochemical immunoassays.

Rackus DG, Dryden MD, Lamanna J, Zaragoza A, Lam B, Kelley SO, Wheeler AR.

Lab Chip. 2015;15(18):3776-84. doi: 10.1039/c5lc00660k.

PMID:
26247922
43.

An electrochemical clamp assay for direct, rapid analysis of circulating nucleic acids in serum.

Das J, Ivanov I, Montermini L, Rak J, Sargent EH, Kelley SO.

Nat Chem. 2015 Jul;7(7):569-75. doi: 10.1038/nchem.2270. Epub 2015 Jun 1.

PMID:
26100805
44.

Mitochondrial Targeting of Doxorubicin Eliminates Nuclear Effects Associated with Cardiotoxicity.

Jean SR, Tulumello DV, Riganti C, Liyanage SU, Schimmer AD, Kelley SO.

ACS Chem Biol. 2015 Sep 18;10(9):2007-15. doi: 10.1021/acschembio.5b00268. Epub 2015 Jun 18.

45.

Sample-to-Answer Isolation and mRNA Profiling of Circulating Tumor Cells.

Mohamadi RM, Ivanov I, Stojcic J, Nam RK, Sargent EH, Kelley SO.

Anal Chem. 2015 Jun 16;87(12):6258-64. doi: 10.1021/acs.analchem.5b01019. Epub 2015 Jun 2.

PMID:
26009151
46.

Rapid electrochemical phenotypic profiling of antibiotic-resistant bacteria.

Besant JD, Sargent EH, Kelley SO.

Lab Chip. 2015 Jul 7;15(13):2799-807. doi: 10.1039/c5lc00375j. Epub 2015 May 26.

PMID:
26008802
47.

Nanoparticle-based sorting of circulating tumor cells by epithelial antigen expression during disease progression in an animal model.

Muhanna N, Mepham A, Mohamadi RM, Chan H, Khan T, Akens M, Besant JD, Irish J, Kelley SO.

Nanomedicine. 2015 Oct;11(7):1613-20. doi: 10.1016/j.nano.2015.04.017. Epub 2015 May 14.

PMID:
25981337
48.

In Situ Electrochemical ELISA for Specific Identification of Captured Cancer Cells.

Safaei TS, Mohamadi RM, Sargent EH, Kelley SO.

ACS Appl Mater Interfaces. 2015 Jul 8;7(26):14165-9. doi: 10.1021/acsami.5b02404. Epub 2015 May 13.

PMID:
25938818
49.

Programmable definition of nanogap electronic devices using self-inhibited reagent depletion.

Lam B, Zhou W, Kelley SO, Sargent EH.

Nat Commun. 2015 Apr 27;6:6940. doi: 10.1038/ncomms7940.

50.

Ultrasensitive visual read-out of nucleic acids using electrocatalytic fluid displacement.

Besant JD, Das J, Burgess IB, Liu W, Sargent EH, Kelley SO.

Nat Commun. 2015 Apr 22;6:6978. doi: 10.1038/ncomms7978.

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