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Items: 1 to 50 of 129

1.

P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients.

Kappler M, Kotrba J, Kaune T, Bache M, Rot S, Bethmann D, Wichmann H, Güttler A, Bilkenroth U, Horter S, Gallwitz L, Kessler J, Greither T, Taubert H, Eckert AW, Vordermark D.

Clin Transl Radiat Oncol. 2017 Jun 27;5:6-11. doi: 10.1016/j.ctro.2017.05.002. eCollection 2017 Aug.

2.

Correction to: Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma.

Eckert AW, Wickenhauser C, Salins PC, Kappler M, Bukur J, Seliger B.

J Transl Med. 2018 Feb 28;16(1):40. doi: 10.1186/s12967-018-1407-9.

3.

CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.

Greither T, Wedler A, Rot S, Keßler J, Kehlen A, Holzhausen HJ, Bache M, Würl P, Taubert H, Kappler M.

Int J Mol Sci. 2017 Dec 7;18(12). pii: E2648. doi: 10.3390/ijms18122648.

4.

International management platform for children's interstitial lung disease (chILD-EU).

Griese M, Seidl E, Hengst M, Reu S, Rock H, Anthony G, Kiper N, Emiralioğlu N, Snijders D, Goldbeck L, Leidl R, Ley-Zaporozhan J, Krüger-Stollfuss I, Kammer B, Wesselak T, Eismann C, Schams A, Neuner D, MacLean M, Nicholson AG, Lauren M, Clement A, Epaud R, de Blic J, Ashworth M, Aurora P, Calder A, Wetzke M, Kappler M, Cunningham S, Schwerk N, Bush A; the other chILD-EU collaborators.

Thorax. 2018 Mar;73(3):231-239. doi: 10.1136/thoraxjnl-2017-210519. Epub 2017 Oct 22.

5.

Multiparametric immune profiling in HPV- oral squamous cell cancer.

Feng Z, Bethmann D, Kappler M, Ballesteros-Merino C, Eckert A, Bell RB, Cheng A, Bui T, Leidner R, Urba WJ, Johnson K, Hoyt C, Bifulco CB, Bukur J, Wickenhauser C, Seliger B, Fox BA.

JCI Insight. 2017 Jul 20;2(14). pii: 93652. doi: 10.1172/jci.insight.93652. [Epub ahead of print]

6.

A Multicentre Study on the Efficacy, Safety and Pharmacokinetics of IqYmune®, a Highly Purified 10% Liquid Intravenous Immunoglobulin, in Patients with Primary Immune Deficiency.

Krivan G, Chernyshova L, Kostyuchenko L, Lange A, Nyul Z, Derfalvi B, Musial J, Bellon A, Kappler M, Sadoun A, Bernatowska E.

J Clin Immunol. 2017 Aug;37(6):539-547. doi: 10.1007/s10875-017-0416-4. Epub 2017 Jul 15.

7.

Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma.

Greither T, Vorwerk F, Kappler M, Bache M, Taubert H, Kuhnt T, Hey J, Eckert AW.

Oncol Rep. 2017 Aug;38(2):1268-1275. doi: 10.3892/or.2017.5764. Epub 2017 Jun 28.

PMID:
28677748
8.

[Upper Jaw Malignoma: Results of a Monocentric Study Over 45 Years].

Böhm M, Kappler M, Dauter K, Reich W, Eckert AW.

Zentralbl Chir. 2018 Feb;143(1):68-73. doi: 10.1055/s-0043-111238. Epub 2017 Jul 4. German.

PMID:
28675918
9.

Increasing Total Serum IgE, Allergic Bronchopulmonary Aspergillosis, and Lung Function in Cystic Fibrosis.

Gothe F, Kappler M, Griese M.

J Allergy Clin Immunol Pract. 2017 Nov - Dec;5(6):1591-1598.e6. doi: 10.1016/j.jaip.2017.03.033. Epub 2017 May 16.

PMID:
28526275
10.

miR-199a-5p regulates HIF-1α and OSGIN2 and its expression is correlated to soft-tissue sarcoma patients' outcome.

Keßler J, Rot S, Bache M, Kappler M, Würl P, Vordermark D, Taubert H, Greither T.

Oncol Lett. 2016 Dec;12(6):5281-5288. doi: 10.3892/ol.2016.5320. Epub 2016 Oct 26.

11.

Pott's disease: a major issue for an unaccompanied refugee minor.

Papan C, von Both U, Kappler M, Kammer B, Griese M, Huebner J.

Thorax. 2017 Mar;72(3):282-283. doi: 10.1136/thoraxjnl-2016-209468. Epub 2016 Nov 21.

PMID:
27872320
12.

Lung disease caused by ABCA3 mutations.

Kröner C, Wittmann T, Reu S, Teusch V, Klemme M, Rauch D, Hengst M, Kappler M, Cobanoglu N, Sismanlar T, Aslan AT, Campo I, Proesmans M, Schaible T, Terheggen-Lagro S, Regamey N, Eber E, Seidenberg J, Schwerk N, Aslanidis C, Lohse P, Brasch F, Zarbock R, Griese M.

Thorax. 2017 Mar;72(3):213-220. doi: 10.1136/thoraxjnl-2016-208649. Epub 2016 Aug 11.

PMID:
27516224
13.

Eradication of methicillin resistant Staphylococcus aureus detected for the first time in cystic fibrosis: A single center observational study.

Kappler M, Nagel F, Feilcke M, Kröner C, Pawlita I, Naehrig S, Ripper J, Hengst M, von Both U, Forstner M, Hector A, Griese M.

Pediatr Pulmonol. 2016 Oct;51(10):1010-1019. doi: 10.1002/ppul.23519. Epub 2016 Jul 5.

PMID:
27378061
14.

The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with S-nitroso-tert-dodecyl mercaptan.

Ketchum AR, Kappler MP, Wu J, Xi C, Meyerhoff ME.

J Mater Chem B. 2016 Jan 21;4(3):422-430. Epub 2015 Dec 7.

15.

Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma.

Eckert AW, Wickenhauser C, Salins PC, Kappler M, Bukur J, Seliger B.

J Transl Med. 2016 Apr 5;14:85. doi: 10.1186/s12967-016-0828-6. Review. Erratum in: J Transl Med. 2018 Feb 28;16(1):40.

16.

Normoxic accumulation of HIF1α is associated with glutaminolysis.

Kappler M, Pabst U, Rot S, Taubert H, Wichmann H, Schubert J, Bache M, Weinholdt C, Immel UD, Grosse I, Vordermark D, Eckert AW.

Clin Oral Investig. 2017 Jan;21(1):211-224. doi: 10.1007/s00784-016-1780-9. Epub 2016 Mar 9.

PMID:
26955835
17.

Increased risk of interstitial lung disease in children with a single R288K variant of ABCA3.

Wittmann T, Frixel S, Höppner S, Schindlbeck U, Schams A, Kappler MV, Hegermann J, Wrede C, Liebisch G, Vierzig A, Zacharasiewicz A, Kopp M, Poets CF, Baden W, Hartl D, Van Kaam AH, Lohse P, Aslanidis C, Zarbock R, Griese M.

Mol Med. 2016 Feb 26. doi: 10.2119/molmed.2015.00244. [Epub ahead of print]

18.

Microbial colonization and lung function in adolescents with cystic fibrosis.

Hector A, Kirn T, Ralhan A, Graepler-Mainka U, Berenbrinker S, Riethmueller J, Hogardt M, Wagner M, Pfleger A, Autenrieth I, Kappler M, Griese M, Eber E, Martus P, Hartl D.

J Cyst Fibros. 2016 May;15(3):340-9. doi: 10.1016/j.jcf.2016.01.004. Epub 2016 Feb 5.

19.

Persistent Tachypnea of Infancy. Usual and Aberrant.

Rauch D, Wetzke M, Reu S, Wesselak W, Schams A, Hengst M, Kammer B, Ley-Zaporozhan J, Kappler M, Proesmans M, Lange J, Escribano A, Kerem E, Ahrens F, Brasch F, Schwerk N, Griese M; PTI (Persistent Tachypnea of Infancy) Study Group of the Kids Lung Register.

Am J Respir Crit Care Med. 2016 Feb 15;193(4):438-47. doi: 10.1164/rccm.201508-1655OC.

20.

S-Nitroso-N-acetylpenicillamine (SNAP) Impregnated Silicone Foley Catheters: A Potential Biomaterial/Device To Prevent Catheter-Associated Urinary Tract Infections.

Colletta A, Wu J, Wo Y, Kappler M, Chen H, Xi C, Meyerhoff ME.

ACS Biomater Sci Eng. 2015 Jun 8;1(6):416-424. Epub 2015 Apr 27.

21.

Categorizing diffuse parenchymal lung disease in children.

Griese M, Irnstetter A, Hengst M, Burmester H, Nagel F, Ripper J, Feilcke M, Pawlita I, Gothe F, Kappler M, Schams A, Wesselak T, Rauch D, Wittmann T, Lohse P, Brasch F, Kröner C.

Orphanet J Rare Dis. 2015 Sep 25;10:122. doi: 10.1186/s13023-015-0339-1.

22.

Surfactant proteins in pediatric interstitial lung disease.

Griese M, Lorenz E, Hengst M, Schams A, Wesselak T, Rauch D, Wittmann T, Kirchberger V, Escribano A, Schaible T, Baden W, Schulze J, Krude H, Aslanidis C, Schwerk N, Kappler M, Hartl D, Lohse P, Zarbock R.

Pediatr Res. 2016 Jan;79(1-1):34-41. doi: 10.1038/pr.2015.173. Epub 2015 Sep 16.

PMID:
26375475
23.

IDH1(R132H) mutation causes a less aggressive phenotype and radiosensitizes human malignant glioma cells independent of the oxygenation status.

Kessler J, Güttler A, Wichmann H, Rot S, Kappler M, Bache M, Vordermark D.

Radiother Oncol. 2015 Sep;116(3):381-7. doi: 10.1016/j.radonc.2015.08.007. Epub 2015 Aug 29.

PMID:
26328938
24.

GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders.

Griese M, Zarbock R, Costabel U, Hildebrandt J, Theegarten D, Albert M, Thiel A, Schams A, Lange J, Krenke K, Wesselak T, Schön C, Kappler M, Blum H, Krebs S, Jung A, Kröner C, Klein C, Campo I, Luisetti M, Bonella F.

BMC Pulm Med. 2015 Aug 12;15:87. doi: 10.1186/s12890-015-0083-2.

25.

mRNA expression levels of hypoxia-induced and stem cell-associated genes in human glioblastoma.

Bache M, Rot S, Keßler J, Güttler A, Wichmann H, Greither T, Wach S, Taubert H, Söling A, Bilkenroth U, Kappler M, Vordermark D.

Oncol Rep. 2015 Jun;33(6):3155-61. doi: 10.3892/or.2015.3932. Epub 2015 Apr 27.

PMID:
25963717
26.

Endobronchial lesions caused by nontuberculous mycobacteria in apparently healthy pediatric patients.

Kröner C, Griese M, Kappler M, Schoen C, Hoffmann F, Nicolai T, Reiter K.

Pediatr Infect Dis J. 2015 May;34(5):532-5. doi: 10.1097/INF.0000000000000606.

PMID:
25478650
27.

Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma--an in vitro study of cytotoxicity and radiosensitization.

Bache M, Bernhardt S, Passin S, Wichmann H, Hein A, Zschornak M, Kappler M, Taubert H, Paschke R, Vordermark D.

Int J Mol Sci. 2014 Oct 30;15(11):19777-90. doi: 10.3390/ijms151119777.

28.

Targeting of EGFR and HER2 with therapeutic antibodies and siRNA: a comparative study in glioblastoma cells.

Wichmann H, Güttler A, Bache M, Taubert H, Rot S, Kessler J, Eckert AW, Kappler M, Vordermark D.

Strahlenther Onkol. 2015 Feb;191(2):180-91. doi: 10.1007/s00066-014-0743-9. Epub 2014 Aug 27.

PMID:
25159136
29.

Predictive values of antibodies against Pseudomonas aeruginosa in patients with cystic fibrosis one year after early eradication treatment.

Kappler M, Nagel F, Feilcke M, Heilig G, Grimmelt AC, Pawlita I, Irnstetter A, Hildebrandt J, Burmester H, Kröner C, Griese M.

J Cyst Fibros. 2014 Sep;13(5):534-41. doi: 10.1016/j.jcf.2014.06.006. Epub 2014 Jul 5.

30.

Inverse prognostic impact of ErbB2 mRNA and protein expression level in tumors of soft tissue sarcoma patients.

Wichmann H, Güttler A, Bache M, Taubert H, Vetter M, Würl P, Holzhausen HJ, Eckert AW, Kappler M, Vordermark D.

Strahlenther Onkol. 2014 Oct;190(10):912-8. doi: 10.1007/s00066-014-0655-8. Epub 2014 Apr 9.

PMID:
24715245
31.

High coexpression of CCL2 and CX3CL1 is gender-specifically associated with good prognosis in soft tissue sarcoma patients.

Kehlen A, Greither T, Wach S, Nolte E, Kappler M, Bache M, Holzhausen HJ, Lautenschläger C, Göbel S, Würl P, Immel UD, Agaimy A, Wullich B, Taubert H.

Int J Cancer. 2014 Nov 1;135(9):2096-106. doi: 10.1002/ijc.28867. Epub 2014 Apr 4.

32.

The basidiomycetous yeast Trichosporon may cause severe lung exacerbation in cystic fibrosis patients - clinical analysis of Trichosporon positive patients in a Munich cohort.

Kröner C, Kappler M, Grimmelt AC, Laniado G, Würstl B, Griese M.

BMC Pulm Med. 2013 Nov 1;13:61. doi: 10.1186/1471-2466-13-61.

33.

Osteopontin and splice variant expression level in human malignant glioma: radiobiologic effects and prognosis after radiotherapy.

Güttler A, Giebler M, Cuno P, Wichmann H, Keßler J, Ostheimer C, Söling A, Strauss C, Illert J, Kappler M, Vordermark D, Bache M.

Radiother Oncol. 2013 Sep;108(3):535-40. doi: 10.1016/j.radonc.2013.06.036. Epub 2013 Jul 25.

PMID:
23891093
34.

A pharmacokinetics and safety comparison of a highly concentrated tobramycin solution with TOBI.

Griese M, Eismann C, Börner G, Denk O, Schierholz JM, Keller M, Mazurek H, Kappler M.

J Aerosol Med Pulm Drug Deliv. 2014 Jun;27(3):185-92. doi: 10.1089/jamp.2012.1022. Epub 2013 Jun 22.

PMID:
23789705
35.

Inhalation treatment with glutathione in patients with cystic fibrosis. A randomized clinical trial.

Griese M, Kappler M, Eismann C, Ballmann M, Junge S, Rietschel E, van Koningsbruggen-Rietschel S, Staab D, Rolinck-Werninghaus C, Mellies U, Köhnlein T, Wagner T, König S, Teschler H, Heuer HE, Kopp M, Heyder S, Hammermann J, Küster P, Honer M, Mansmann U, Beck-Speier I, Hartl D, Fuchs C; Glutathione Study Group, Hector A.

Am J Respir Crit Care Med. 2013 Jul 1;188(1):83-9. doi: 10.1164/rccm.201303-0427OC.

PMID:
23631796
36.

Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome.

Griese M, Heinrich S, Ratjen F, Kabesch M, Paul K, Ballmann M, Rietschel E, Kappler M.

PLoS One. 2012;7(12):e51050. doi: 10.1371/journal.pone.0051050. Epub 2012 Dec 7.

37.

Expression and regulation of interferon-related development regulator-1 in cystic fibrosis neutrophils.

Hector A, Kormann M, Kammermeier J, Burdi S, Marcos V, Rieber N, Mays L, Illig T, Klopp N, Falkenstein F, Kappler M, Riethmueller J, Graepler-Mainka U, Stern M, Eickmeier O, Serve F, Zielen S, Döring G, Griese M, Hartl D.

Am J Respir Cell Mol Biol. 2013 Jan;48(1):71-7. doi: 10.1165/rcmb.2012-0061OC. Epub 2012 Oct 4.

PMID:
23043087
38.

The real face of HIF1α in the tumor process.

Kappler M, Taubert H, Schubert J, Vordermark D, Eckert AW.

Cell Cycle. 2012 Nov 1;11(21):3932-6. doi: 10.4161/cc.21854. Epub 2012 Sep 17.

39.

Expression of human Piwi-like genes is associated with prognosis for soft tissue sarcoma patients.

Greither T, Koser F, Kappler M, Bache M, Lautenschläger C, Göbel S, Holzhausen HJ, Wach S, Würl P, Taubert H.

BMC Cancer. 2012 Jun 29;12:272. doi: 10.1186/1471-2407-12-272.

40.

Ursodeoxycholic acid therapy in cystic fibrosis liver disease--a retrospective long-term follow-up case-control study.

Kappler M, Espach C, Schweiger-Kabesch A, Lang T, Hartl D, Hector A, Glasmacher C, Griese M.

Aliment Pharmacol Ther. 2012 Aug;36(3):266-73. doi: 10.1111/j.1365-2036.2012.05177.x. Epub 2012 Jun 7.

41.

Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients.

Eckert AW, Kappler M, Schubert J, Taubert H.

Oral Maxillofac Surg. 2012 Jun;16(2):189-96. doi: 10.1007/s10006-012-0335-8. Epub 2012 May 17. Review.

PMID:
22592457
42.

Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients.

Hahnel A, Wichmann H, Greither T, Kappler M, Würl P, Kotzsch M, Taubert H, Vordermark D, Bache M.

BMC Cancer. 2012 Apr 2;12:131. doi: 10.1186/1471-2407-12-131.

43.

CXCR1 and CXCR2 haplotypes synergistically modulate cystic fibrosis lung disease.

Kormann MS, Hector A, Marcos V, Mays LE, Kappler M, Illig T, Klopp N, Zeilinger S, Carevic M, Rieber N, Eickmeier O, Zielen S, Gaggar A, Moepps B, Griese M, Hartl D.

Eur Respir J. 2012 Jun;39(6):1385-90. doi: 10.1183/09031936.00130011. Epub 2011 Nov 16.

44.

Oxygen sensing, homeostasis, and disease.

Kappler M, Taubert H, Eckert AW.

N Engl J Med. 2011 Nov 10;365(19):1845-6; author reply 1846. doi: 10.1056/NEJMc1110602. No abstract available.

PMID:
22070494
45.

A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients.

Rot S, Taubert H, Bache M, Greither T, Würl P, Eckert AW, Schubert J, Vordermark D, Kappler M.

BMC Cancer. 2011 Oct 6;11:429. doi: 10.1186/1471-2407-11-429.

46.

The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease.

Hector A, Kormann MS, Mack I, Latzin P, Casaulta C, Kieninger E, Zhou Z, Yildirim AÖ, Bohla A, Rieber N, Kappler M, Koller B, Eber E, Eickmeier O, Zielen S, Eickelberg O, Griese M, Mall MA, Hartl D.

PLoS One. 2011;6(9):e24399. doi: 10.1371/journal.pone.0024399. Epub 2011 Sep 20.

47.

Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions.

Bache M, Zschornak MP, Passin S, Kessler J, Wichmann H, Kappler M, Paschke R, Kaluđerović GN, Kommera H, Taubert H, Vordermark D.

Radiat Oncol. 2011 Sep 9;6:111. doi: 10.1186/1748-717X-6-111.

48.

Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients.

Kotzsch M, Magdolen V, Greither T, Kappler M, Bache M, Lautenschläger C, Füssel S, Eckert AW, Luther T, Baretton G, Würl P, Taubert H.

BMC Cancer. 2011 Jun 25;11:273. doi: 10.1186/1471-2407-11-273.

49.

Expression of microRNA 210 associates with poor survival and age of tumor onset of soft-tissue sarcoma patients.

Greither T, Würl P, Grochola L, Bond G, Bache M, Kappler M, Lautenschläger C, Holzhausen HJ, Wach S, Eckert AW, Taubert H.

Int J Cancer. 2012 Mar 1;130(5):1230-5. doi: 10.1002/ijc.26109. Epub 2011 Jun 21.

50.

Seizures and stupor during intravenous mannose therapy in a patient with CDG syndrome type 1b (MPI-CDG).

Schroeder AS, Kappler M, Bonfert M, Borggraefe I, Schoen C, Reiter K.

J Inherit Metab Dis. 2010 Dec;33 Suppl 3:S497-502. doi: 10.1007/s10545-010-9252-x. Epub 2011 Jan 16.

PMID:
21240668

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