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Items: 18

1.

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure.

Abdi AI, Hodgson SH, Muthui MK, Kivisi CA, Kamuyu G, Kimani D, Hoffman SL, Juma E, Ogutu B, Draper SJ, Osier F, Bejon P, Marsh K, Bull PC.

BMC Infect Dis. 2017 Aug 23;17(1):585. doi: 10.1186/s12879-017-2686-0.

2.

Vaccine candidate discovery for the next generation of malaria vaccines.

Tuju J, Kamuyu G, Murungi LM, Osier FHA.

Immunology. 2017 Oct;152(2):195-206. doi: 10.1111/imm.12780. Epub 2017 Jul 24. Review.

3.

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.

Hodgson SH, Llewellyn D, Silk SE, Milne KH, Elias SC, Miura K, Kamuyu G, Juma EA, Magiri C, Muia A, Jin J, Spencer AJ, Longley RJ, Mercier T, Decosterd L, Long CA, Osier FH, Hoffman SL, Ogutu B, Hill AV, Marsh K, Draper SJ.

Front Microbiol. 2016 Oct 13;7:1604. eCollection 2016.

4.

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants.

Crosnier C, Iqbal Z, Knuepfer E, Maciuca S, Perrin AJ, Kamuyu G, Goulding D, Bustamante LY, Miles A, Moore SC, Dougan G, Holder AA, Kwiatkowski DP, Rayner JC, Pleass RJ, Wright GJ.

J Biol Chem. 2016 Jul 1;291(27):14285-99. doi: 10.1074/jbc.M116.722074. Epub 2016 May 12.

5.

Incidence, Remission and Mortality of Convulsive Epilepsy in Rural Northeast South Africa.

Wagner RG, Bottomley C, Ngugi AK, Ibinda F, Gómez-Olivé FX, Kahn K, Tollman S, Newton CR; SEEDS Writing Group, Wagner R, Twine R, Connor M, Collinson M, Masanja H, Mathew A, Kakooza A, Pariyo G, Peterson S, Ndyo-mughenyi D, Odhiambo R, Chengo E, Chabi M, Bauni E, Kamuyu G, Odera VM, Mageto JO, Ae-Ngibise K, Akpalu B, Akpalu A, Agbokey F, Adjei P, Owusu-Agyei S, Kleinschmidt I, Doku VC, Odermatt P, Neville B, Sander JW, White S, Nutman T, Wilkins P, Noh J.

PLoS One. 2015 Jun 8;10(6):e0129097. doi: 10.1371/journal.pone.0129097. eCollection 2015.

6.

Multiple clinical episodes of Plasmodium falciparum malaria in a low transmission intensity setting: exposure versus immunity.

Rono J, Färnert A, Murungi L, Ojal J, Kamuyu G, Guleid F, Nyangweso G, Wambua J, Kitsao B, Olotu A, Marsh K, Osier FH.

BMC Med. 2015 May 13;13:114. doi: 10.1186/s12916-015-0354-z.

7.

Cysticercosis and epilepsy in rural Tanzania: a community-based case-control and imaging study.

Hunter E, Burton K, Iqbal A, Birchall D, Jackson M, Rogathe J, Jusabani A, Gray W, Aris E, Kamuyu G, Wilkins PP, Newton CR, Walker R.

Trop Med Int Health. 2015 Sep;20(9):1171-1179. doi: 10.1111/tmi.12529. Epub 2015 May 26.

8.

Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy.

Kariuki SM, Kakooza-Mwesige A, Wagner RG, Chengo E, White S, Kamuyu G, Ngugi AK, Sander JW, Neville BG, Newton CR; SEEDS Writing Group.

Neurology. 2015 May 5;84(18):1838-45. doi: 10.1212/WNL.0000000000001542. Epub 2015 Apr 3.

9.

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.

Hodgson SH, Juma E, Salim A, Magiri C, Kimani D, Njenga D, Muia A, Cole AO, Ogwang C, Awuondo K, Lowe B, Munene M, Billingsley PF, James ER, Gunasekera A, Sim BK, Njuguna P, Rampling TW, Richman A, Abebe Y, Kamuyu G, Muthui M, Elias SC, Molyneux S, Gerry S, Macharia A, Williams TN, Bull PC, Hill AV, Osier FH, Draper SJ, Bejon P, Hoffman SL, Ogutu B, Marsh K.

Front Microbiol. 2014 Dec 12;5:686. doi: 10.3389/fmicb.2014.00686. eCollection 2014.

10.

New antigens for a multicomponent blood-stage malaria vaccine.

Osier FH, Mackinnon MJ, Crosnier C, Fegan G, Kamuyu G, Wanaguru M, Ogada E, McDade B, Rayner JC, Wright GJ, Marsh K.

Sci Transl Med. 2014 Jul 30;6(247):247ra102. doi: 10.1126/scitranslmed.3008705.

11.

Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa.

Kamuyu G, Bottomley C, Mageto J, Lowe B, Wilkins PP, Noh JC, Nutman TB, Ngugi AK, Odhiambo R, Wagner RG, Kakooza-Mwesige A, Owusu-Agyei S, Ae-Ngibise K, Masanja H, Osier FH, Odermatt P, Newton CR; Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group.

PLoS Negl Trop Dis. 2014 May 29;8(5):e2908. doi: 10.1371/journal.pntd.0002908. eCollection 2014.

12.

Prevalence and risk factors for active convulsive epilepsy in rural northeast South Africa.

Wagner RG, Ngugi AK, Twine R, Bottomley C, Kamuyu G, Gómez-Olivé FX, Connor MD, Collinson MA, Kahn K, Tollman S, Newton CR.

Epilepsy Res. 2014 May;108(4):782-91. doi: 10.1016/j.eplepsyres.2014.01.004. Epub 2014 Jan 29.

13.

Clinical features, proximate causes, and consequences of active convulsive epilepsy in Africa.

Kariuki SM, Matuja W, Akpalu A, Kakooza-Mwesige A, Chabi M, Wagner RG, Connor M, Chengo E, Ngugi AK, Odhiambo R, Bottomley C, White S, Sander JW, Neville BG, Newton CR; SEEDS writing group, Twine R, Gómez Olivé FX, Collinson M, Kahn K, Tollman S, Masanja H, Mathew A, Pariyo G, Peterson S, Ndyomughenyi D, Bauni E, Kamuyu G, Odera VM, Mageto JO, Ae-Ngibise K, Akpalu B, Agbokey F, Adjei P, Owusu-Agyei S, Kleinschmidt I, Doku VC, Odermatt P, Nutman T, Wilkins P, Noh J.

Epilepsia. 2014 Jan;55(1):76-85. doi: 10.1111/epi.12392. Epub 2013 Oct 7.

14.

Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity.

Tetteh KK, Osier FH, Salanti A, Kamuyu G, Drought L, Failly M, Martin C, Marsh K, Conway DJ.

Infect Immun. 2013 Oct;81(10):3835-42. doi: 10.1128/IAI.00301-13. Epub 2013 Jul 29.

15.

A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria.

Murungi LM, Kamuyu G, Lowe B, Bejon P, Theisen M, Kinyanjui SM, Marsh K, Osier FH.

Vaccine. 2013 Aug 20;31(37):3936-42. doi: 10.1016/j.vaccine.2013.06.042. Epub 2013 Jun 22.

16.

The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children.

Warimwe GM, Murungi LM, Kamuyu G, Nyangweso GM, Wambua J, Naranbhai V, Fletcher HA, Hill AV, Bejon P, Osier FH, Marsh K.

PLoS One. 2013;8(2):e57320. doi: 10.1371/journal.pone.0057320. Epub 2013 Feb 20.

17.

Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies.

Ngugi AK, Bottomley C, Kleinschmidt I, Wagner RG, Kakooza-Mwesige A, Ae-Ngibise K, Owusu-Agyei S, Masanja H, Kamuyu G, Odhiambo R, Chengo E, Sander JW, Newton CR; SEEDS group.

Lancet Neurol. 2013 Mar;12(3):253-63. doi: 10.1016/S1474-4422(13)70003-6. Epub 2013 Jan 31.

18.

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody.

Douglas AD, Williams AR, Illingworth JJ, Kamuyu G, Biswas S, Goodman AL, Wyllie DH, Crosnier C, Miura K, Wright GJ, Long CA, Osier FH, Marsh K, Turner AV, Hill AV, Draper SJ.

Nat Commun. 2011 Dec 20;2:601. doi: 10.1038/ncomms1615. Erratum in: Nat Commun. 2013;4. doi:10.1038/ncomms3355.

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