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18F- FDG PET/CT joint assessment of early therapeutic response in rheumatoid arthritis patients treated with rituximab.

Fosse P, Kaiser MJ, Namur G, de Seny D, Malaise MG, Hustinx R.

Eur J Hybrid Imaging. 2018;2(1):6. doi: 10.1186/s41824-017-0022-y. Epub 2018 Feb 5.


Applications of Deep Learning and Reinforcement Learning to Biological Data.

Mahmud M, Kaiser MS, Hussain A, Vassanelli S.

IEEE Trans Neural Netw Learn Syst. 2018 Jun;29(6):2063-2079. doi: 10.1109/TNNLS.2018.2790388.


Mind Control: How Parasites Manipulate Cognitive Functions in Their Insect Hosts.

Libersat F, Kaiser M, Emanuel S.

Front Psychol. 2018 May 1;9:572. doi: 10.3389/fpsyg.2018.00572. eCollection 2018.


Rapid evolution to host plant resistance by an invasive herbivore: soybean aphid (Aphis glycines) virulence in North America to aphid resistant cultivars.

O'Neal ME, Varenhorst AJ, Kaiser MC.

Curr Opin Insect Sci. 2018 Apr;26:1-7. doi: 10.1016/j.cois.2017.12.006. Epub 2018 Jan 5. Review.


C-H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity.

O' Donovan DH, Aillard P, Berger M, de la Torre A, Petkova D, Knittl-Frank C, Geerdink D, Kaiser M, Maulide N.

Angew Chem Int Ed Engl. 2018 May 15. doi: 10.1002/anie.201804551. [Epub ahead of print]


The Antimalarial Activity of Artemisinin is not Stereospecific.

Giannis A, Krieger J, Smeilus T, Kaiser M, Seo EJ, Efferth T.

Angew Chem Int Ed Engl. 2018 May 3. doi: 10.1002/anie.201802015. [Epub ahead of print]


Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network.

Ludwig H, Delforge M, Facon T, Einsele H, Gay F, Moreau P, Avet-Loiseau H, Boccadoro M, Hajek R, Mohty M, Cavo M, Dimopoulos MA, San-Miguel JF, Terpos E, Zweegman S, Garderet L, Mateos MV, Cook G, Leleu X, Goldschmidt H, Jackson G, Kaiser M, Weisel K, van de Donk NWCJ, Waage A, Beksac M, Mellqvist UH, Engelhardt M, Caers J, Driessen C, Bladé J, Sonneveld P.

Leukemia. 2018 May 2. doi: 10.1038/s41375-018-0040-1. [Epub ahead of print] Review.


Antiprotozoal Diterpenes from Perovskia abrotanoides.

Tabefam M, Farimani MM, Danton O, Ramseyer J, Kaiser M, Ebrahimi SN, Salehi P, Batooli H, Potterat O, Hamburger M.

Planta Med. 2018 Apr 26. doi: 10.1055/a-0608-4946. [Epub ahead of print]


A World Health Organization Human Hepatitis E Virus Reference Strain Related to Similar Strains Isolated from Rabbits.

Kaiser M, Delaune D, Chazouillères O, Blümel J, Roque-Afonso AM, Baylis SA.

Genome Announc. 2018 Apr 19;6(16). pii: e00292-18. doi: 10.1128/genomeA.00292-18.


Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides.

Wesche F, Adihou H, Kaiser A, Wurglics M, Schubert-Zsilavecz M, Kaiser M, Bode HB.

J Med Chem. 2018 May 10;61(9):3930-3938. doi: 10.1021/acs.jmedchem.7b01809. Epub 2018 Apr 20.


Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes.

Bongard J, Lorenz M, Vetter IR, Stege P, Porfetye AT, Schmitz AL, Kaschani F, Wolf A, Koch U, Nussbaumer P, Klebl B, Kaiser M, Ehrmann M.

ACS Chem Biol. 2018 May 18;13(5):1307-1312. doi: 10.1021/acschembio.8b00101. Epub 2018 Apr 16.


Whole-genome sequencing of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms.

Hoang PH, Dobbins SE, Cornish AJ, Chubb D, Law PJ, Kaiser M, Houlston RS.

Leukemia. 2018 Apr 9. doi: 10.1038/s41375-018-0103-3. [Epub ahead of print]


Smoking and local unemployment: Evidence from Germany.

Kaiser M, Reutter M, Sousa-Poza A, Strohmaier K.

Econ Hum Biol. 2018 May;29:138-147. doi: 10.1016/j.ehb.2018.02.004. Epub 2018 Mar 1.


Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.

De Gasparo R, Brodbeck-Persch E, Bryson S, Hentzen NB, Kaiser M, Pai EF, Krauth-Siegel RL, Diederich F.

ChemMedChem. 2018 May 8;13(9):957-967. doi: 10.1002/cmdc.201800067. Epub 2018 Apr 6.


Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent.

Zhang H, Collins J, Nyamwihura R, Ware S, Kaiser M, Ogungbe IV.

Bioorg Med Chem Lett. 2018 May 15;28(9):1647-1651. doi: 10.1016/j.bmcl.2018.03.039. Epub 2018 Mar 24.


2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.

Giroud M, Kuhn B, Saint-Auret S, Kuratli C, Martin RE, Schuler F, Diederich F, Kaiser M, Brun R, Schirmeister T, Haap W.

J Med Chem. 2018 Apr 26;61(8):3370-3388. doi: 10.1021/acs.jmedchem.7b01870. Epub 2018 Apr 6.


Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.

Giroud M, Dietzel U, Anselm L, Banner D, Kuglstatter A, Benz J, Blanc JB, Gaufreteau D, Liu H, Lin X, Stich A, Kuhn B, Schuler F, Kaiser M, Brun R, Schirmeister T, Kisker C, Diederich F, Haap W.

J Med Chem. 2018 Apr 26;61(8):3350-3369. doi: 10.1021/acs.jmedchem.7b01869. Epub 2018 Apr 13.


Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities.

Tshitenge DT, Feineis D, Mudogo V, Kaiser M, Brun R, Seo EJ, Efferth T, Bringmann G.

J Nat Prod. 2018 Apr 27;81(4):918-933. doi: 10.1021/acs.jnatprod.7b01041. Epub 2018 Mar 21.


Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants.

Husaini AM, Morimoto K, Chandrasekar B, Kelly S, Kaschani F, Palmero D, Jiang J, Kaiser M, Ahrazem O, Overkleeft HS, van der Hoorn RAL.

Plant Physiol. 2018 May;177(1):24-37. doi: 10.1104/pp.18.00250. Epub 2018 Mar 19.


Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense.

Ebiloma GU, Ayuga TD, Balogun EO, Gil LA, Donachie A, Kaiser M, Herraiz T, Inaoka DK, Shiba T, Harada S, Kita K, de Koning HP, Dardonville C.

Eur J Med Chem. 2018 Apr 25;150:385-402. doi: 10.1016/j.ejmech.2018.02.075. Epub 2018 Feb 26.


[Clinical presentation of cowpox virus infection in South American camelids - A review].

Prkno A, Kaiser M, Goerigk D, Pfeffer M, Vahlenkamp TW, Hoffmann D, Beer M, Starke A.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2018 Feb;46(1):50-56. doi: 10.15653/TPG-170502. Epub 2018 Feb 21. German.


Understanding the role of health information in patients' experiences: secondary analysis of qualitative narrative interviews with people diagnosed with cancer in Germany.

Blödt S, Kaiser M, Adam Y, Adami S, Schultze M, Müller-Nordhorn J, Holmberg C.

BMJ Open. 2018 Mar 12;8(3):e019576. doi: 10.1136/bmjopen-2017-019576.


Inflammatory markers before and after farrowing in healthy sows and in sows affected with postpartum dysgalactia syndrome.

Kaiser M, Jacobson M, Andersen PH, Bækbo P, Cerón JJ, Dahl J, Escribano D, Jacobsen S.

BMC Vet Res. 2018 Mar 12;14(1):83. doi: 10.1186/s12917-018-1382-7.


Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein Production.

Santos RB, Chandrasekar B, Mandal MK, Kaschani F, Kaiser M, Both L, van der Hoorn RAL, Schiermeyer A, Abranches R.

Biotechnol J. 2018 Mar 12. doi: 10.1002/biot.201800050. [Epub ahead of print]


Protease activities triggered by Ralstonia solanacearum infection in susceptible and tolerant tomato lines.

Planas-Marquès M, Bernardo-Faura M, Paulus JK, Kaschani F, Kaiser M, Valls M, van der Hoorn R, Coll NS.

Mol Cell Proteomics. 2018 Mar 9. pii: mcp.RA117.000052. doi: 10.1074/mcp.RA117.000052. [Epub ahead of print]


Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in N. benthamiana.

Grosse-Holz F, Madeira L, Zahid MA, Songer M, Kourelis J, Fesenko M, Ninck S, Kaschani F, Kaiser M, van der Hoorn RAL.

Plant Biotechnol J. 2018 Mar 6. doi: 10.1111/pbi.12916. [Epub ahead of print]


The PanCareSurFup cohort of 83,333 five-year survivors of childhood cancer: a cohort from 12 European countries.

Grabow D, Kaiser M, Hjorth L, Byrne J, Alessi D, Allodji RS, Bagnasco F, Bárdi E, Bautz A, Bright CJ, de Vathaire F, Feijen EAM, Garwicz S, Hagberg O, Haupt R, Hawkins MM, Jakab Z, Kremer LCM, Kuehni CE, Kuonen R, Lähteenmäki PM, Reulen RC, Ronckers CM, Sacerdote C, Vu-Bezin G, Wesenberg F, Wiebe T, Winter DL, Winther JF, Zaletel LZ, Kaatsch P; PanCareSurFup Consortium.

Eur J Epidemiol. 2018 Mar;33(3):335-349. doi: 10.1007/s10654-018-0370-3. Epub 2018 Mar 2.


An apoplastic peptide activates salicylic acid signalling in maize.

Ziemann S, van der Linde K, Lahrmann U, Acar B, Kaschani F, Colby T, Kaiser M, Ding Y, Schmelz E, Huffaker A, Holton N, Zipfel C, Doehlemann G.

Nat Plants. 2018 Mar;4(3):172-180. doi: 10.1038/s41477-018-0116-y. Epub 2018 Feb 26.


Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus.

Shi YM, Richter C, Challinor VL, Grün P, Girela Del Rio A, Kaiser M, Schüffler A, Piepenbring M, Schwalbe H, Bode HB.

Org Lett. 2018 Mar 16;20(6):1563-1567. doi: 10.1021/acs.orglett.8b00293. Epub 2018 Feb 23.


Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections.

Uliassi E, Piazzi L, Belluti F, Mazzanti A, Kaiser M, Brun R, Moraes CB, Freitas-Junior LH, Gul S, Kuzikov M, Ellinger B, Borsari C, Costi MP, Bolognesi ML.

ChemMedChem. 2018 Apr 6;13(7):678-683. doi: 10.1002/cmdc.201700786. Epub 2018 Feb 16.


Identification of New Compounds from Sage Flowers (Salvia officinalis L.) as Markers for Quality Control and the Influence of the Manufacturing Technology on the Chemical Composition and Antibacterial Activity of Sage Flower Extracts.

Gericke S, Lübken T, Wolf D, Kaiser M, Hannig C, Speer K.

J Agric Food Chem. 2018 Feb 28;66(8):1843-1853. doi: 10.1021/acs.jafc.8b00581. Epub 2018 Feb 20.


Reduced low-frequency power and phase locking reflect restoration in the auditory continuity illusion.

Kaiser M, Senkowski D, Roa Romero Y, Riecke L, Keil J.

Eur J Neurosci. 2018 Feb 11. doi: 10.1111/ejn.13861. [Epub ahead of print]


KCC2-dependent Steady-state Intracellular Chloride Concentration and pH in Cortical Layer 2/3 Neurons of Anesthetized and Awake Mice.

Boffi JC, Knabbe J, Kaiser M, Kuner T.

Front Cell Neurosci. 2018 Jan 25;12:7. doi: 10.3389/fncel.2018.00007. eCollection 2018.


Machine learning prioritizes synthesis of primaquine ureidoamides with high antimalarial activity and attenuated cytotoxicity.

Levatić J, Pavić K, Perković I, Uzelac L, Ester K, Kralj M, Kaiser M, Rottmann M, Supek F, Zorc B.

Eur J Med Chem. 2018 Feb 25;146:651-667. doi: 10.1016/j.ejmech.2018.01.062. Epub 2018 Jan 31.


Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in Vitro Antitrypanosomal Activity.

Kimani NM, Matasyoh JC, Kaiser M, Brun R, Schmidt TJ.

Molecules. 2018 Jan 27;23(2). pii: E248. doi: 10.3390/molecules23020248.


Transcriptome Analysis in Spleen Reveals Differential Regulation of Response to Newcastle Disease Virus in Two Chicken Lines.

Zhang J, Kaiser MG, Deist MS, Gallardo RA, Bunn DA, Kelly TR, Dekkers JCM, Zhou H, Lamont SJ.

Sci Rep. 2018 Jan 19;8(1):1278. doi: 10.1038/s41598-018-19754-8.


Monitoring single-cell gene regulation under dynamically controllable conditions with integrated microfluidics and software.

Kaiser M, Jug F, Julou T, Deshpande S, Pfohl T, Silander OK, Myers G, van Nimwegen E.

Nat Commun. 2018 Jan 15;9(1):212. doi: 10.1038/s41467-017-02505-0.


Understanding High Incidence of Severe Obesity and Very Low Food Security in Food Pantry Clients: Implications For Social Work.

Kaiser ML, Cafer A.

Soc Work Public Health. 2018;33(2):125-139. doi: 10.1080/19371918.2017.1415181. Epub 2018 Jan 3.


Engineering Asymmetric Lipid Vesicles: Accurate and Convenient Control of the Outer Leaflet Lipid Composition.

Markones M, Drechsler C, Kaiser M, Kalie L, Heerklotz H, Fiedler S.

Langmuir. 2018 Feb 6;34(5):1999-2005. doi: 10.1021/acs.langmuir.7b03189. Epub 2018 Jan 29.


The diagnostic value of hepcidin to predict the presence and severity of appendicitis in children.

Kaiser M, Schroeckenfuchs M, Castellani C, Warncke G, Till H, Singer G.

J Surg Res. 2018 Feb;222:102-107. doi: 10.1016/j.jss.2017.10.021. Epub 2017 Nov 2.


A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

Pöhler R, Krahn JH, van den Boom J, Dobrynin G, Kaschani F, Eggenweiler HM, Zenke FT, Kaiser M, Meyer H.

Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580. doi: 10.1002/anie.201711429. Epub 2018 Jan 15.


Acid-Induced Rearrangement of Epoxygermacranolides: Synthesis of Furanoheliangolides and Cadinanes from Nobilin.

De Mieri M, Smieško M, Ismajili I, Kaiser M, Hamburger M.

Molecules. 2017 Dec 18;22(12). pii: E2252. doi: 10.3390/molecules22122252.


Prevention and management of adverse events of Novel agents in multiple myeloma: A consensus of the european myeloma network.

Ludwig H, Delforge M, Facon T, Einsele H, Gay F, Moreau P, Avet-Loiseau H, Boccadoro M, Hajek R, Mohty M, Cavo M, Dimopoulos MA, San-Miguel JF, Terpos E, Zweegman S, Garderet L, Mateos MV, Cook G, Leleu X, Goldschmidt H, Jackson G, Kaiser M, Weisel K, van de Donk NWCJ, Waage A, Beksac M, Mellqvist UH, Engelhardt M, Caers J, Driessen C, Sonneveld P.

Leukemia. 2017 Dec 18. doi: 10.1038/leu.2017.353. [Epub ahead of print] Review.


Antiprotozoal Sesquiterpene Lactones and Other Constituents from Tarchonanthus camphoratus and Schkuhria pinnata.

Kimani NM, Matasyoh JC, Kaiser M, Brun R, Schmidt TJ.

J Nat Prod. 2018 Jan 26;81(1):124-130. doi: 10.1021/acs.jnatprod.7b00747. Epub 2017 Dec 15.


Hippeastrum reticulatum (Amaryllidaceae): Alkaloid Profiling, Biological Activities and Molecular Docking.

Tallini LR, Osorio EH, Santos VDD, Borges WS, Kaiser M, Viladomat F, Zuanazzi JAS, Bastida J.

Molecules. 2017 Dec 9;22(12). pii: E2191. doi: 10.3390/molecules22122191.


A Chitosan-Based Liposome Formulation Enhances the In Vitro Wound Healing Efficacy of Substance P Neuropeptide.

Mengoni T, Adrian M, Pereira S, Santos-Carballal B, Kaiser M, Goycoolea FM.

Pharmaceutics. 2017 Dec 6;9(4). pii: E56. doi: 10.3390/pharmaceutics9040056.


Functional connectivity in dementia with Lewy bodies: A within- and between-network analysis.

Schumacher J, Peraza LR, Firbank M, Thomas AJ, Kaiser M, Gallagher P, O'Brien JT, Blamire AM, Taylor JP.

Hum Brain Mapp. 2018 Mar;39(3):1118-1129. doi: 10.1002/hbm.23901. Epub 2017 Nov 29.


Treatment outcome in 60 children with pathological fractures of the humerus caused by juvenile or aneurysmal bone cysts.

Rapp M, Grauel F, Wessel LM, Illing P, Kaiser MM.

Acta Orthop Belg. 2016 Dec;82(4):723-729.


Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.

Mohsin NU, Seebacher W, Faist J, Hochegger P, Kaiser M, Mäser P, Belaj F, Saf R, Kretschmer N, Alajlani M, Turek I, Brantner A, Bauer R, Bucar F, Weis R.

Eur J Med Chem. 2018 Jan 1;143:97-106. doi: 10.1016/j.ejmech.2017.11.025. Epub 2017 Nov 10.


Risk of Soft-Tissue Sarcoma Among 69 460 Five-Year Survivors of Childhood Cancer in Europe.

Bright CJ, Hawkins MM, Winter DL, Alessi D, Allodji RS, Bagnasco F, Bárdi E, Bautz A, Byrne J, Feijen EAM, Fidler MM, Garwicz S, Grabow D, Gudmundsdottir T, Guha J, Haddy N, Jankovic M, Kaatsch P, Kaiser M, Kuehni CE, Linge H, Øfstaas H, Ronckers CM, Skinner R, Teepen JC, Terenziani M, Vu-Bezin G, Wesenberg F, Wiebe T, Sacerdote C, Jakab Z, Haupt R, Lähteenmäki P, Zaletel LZ, Kuonen R, Winther JF, de Vathaire F, Kremer LC, Hjorth L, Reulen RC; PanCareSurFup Consortium.

J Natl Cancer Inst. 2017 Nov 20. doi: 10.1093/jnci/djx235. [Epub ahead of print]

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