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Items: 1 to 50 of 85

1.

The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures.

Ziemann C, Riecke A, Rüdell G, Oetjen E, Steinfelder HJ, Lass C, Kahl GF, Hirsch-Ernst KI.

J Pharmacol Exp Ther. 2006 Apr;317(1):378-86. Epub 2006 Jan 13.

3.

The cyclooxygenase system participates in functional mdr1b overexpression in primary rat hepatocyte cultures.

Ziemann C, Schäfer D, Rüdell G, Kahl GF, Hirsch-Ernst KI.

Hepatology. 2002 Mar;35(3):579-88.

PMID:
11870370
4.
5.

Induction of cytochrome P450 2B1 by pyrethroids in primary rat hepatocyte cultures.

Heder AF, Hirsch-Ernst KI, Bauer D, Kahl GF, Desel H.

Biochem Pharmacol. 2001 Jul 1;62(1):71-9.

PMID:
11377398
6.

Repression of phenobarbital-dependent CYP2B1 mRNA induction by reactive oxygen species in primary rat hepatocyte cultures.

Hirsch-Ernst KI, Schlaefer K, Bauer D, Heder AF, Kahl GF.

Mol Pharmacol. 2001 Jun;59(6):1402-9.

7.

[Etiology of initially unexplained confusion of excitability in deadly nightshade poisoning with suicidal intent. Symptoms, differential diagnosis, toxicology and physostigmine therapy of anticholinergic syndrome].

Heindl S, Binder C, Desel H, Matthies U, Lojewski I, Bandelow B, Kahl GF, Chemnitius JM.

Dtsch Med Wochenschr. 2000 Nov 10;125(45):1361-5. German.

PMID:
11109424
8.

Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures.

Hirsch-Ernst KI, Kietzmann T, Ziemann C, Jungermann K, Kahl GF.

Biochem J. 2000 Sep 1;350 Pt 2:443-51.

9.

[Indication for gastric lavage].

Desel H, Kahl GF.

Internist (Berl). 2000 Apr;41(4):388-9. Review. German. No abstract available.

PMID:
10798190
10.

Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats.

Jorritsma U, Schrader E, Klaunick G, Kapitulnik J, Hirsch-Ernst KI, Kahl GF, Foth H.

Toxicology. 2000 Apr 3;144(1-3):229-36.

PMID:
10781892
11.

Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in primary cultures of rat alveolar type II cells.

Schrader E, Hirsch-Ernst KI, Scholz E, Kahl GF, Foth H.

Drug Metab Dispos. 2000 Feb;28(2):180-5.

13.

High-performance liquid chromatographic method for simultaneous determination of [1-methyl-14C]caffeine and its eight major metabolites in rat urine.

Schrader E, Klaunick G, Jorritsma U, Neurath H, Hirsch-Ernst KI, Kahl GF, Foth H.

J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):195-201.

PMID:
10348186
14.

Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures.

Ziemann C, Bürkle A, Kahl GF, Hirsch-Ernst KI.

Carcinogenesis. 1999 Mar;20(3):407-14.

PMID:
10190554
15.

Molecular cDNA cloning and tissue distribution of mRNA encoding a novel ATP-binding cassette (ABC) half-transporter.

Hirsch-Ernst KI, Gaini-Rahimi S, Ernst BP, Schmitz-Salue C, Blume S, Kahl GF.

Biochem Biophys Res Commun. 1998 Aug 10;249(1):151-5.

PMID:
9705847
16.

Differential activation of the c-Ki-ras-2 proto-oncogene in human colorectal carcinoma.

Halatsch ME, Hirsch-Ernst KI, Weinel RJ, Kahl GF.

Anticancer Res. 1998 Jul-Aug;18(4A):2323-5.

PMID:
9703874
17.

Induction of mdr1b mRNA and P-glycoprotein expression by tumor necrosis factor alpha in primary rat hepatocyte cultures.

Hirsch-Ernst KI, Ziemann C, Foth H, Kozian D, Schmitz-Salue C, Kahl GF.

J Cell Physiol. 1998 Sep;176(3):506-15.

PMID:
9699503
18.
19.

Effect of nicotine or cotinine on metabolism of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.

Schulze J, Schrader E, Foth H, Kahl GF, Richter E.

Naunyn Schmiedebergs Arch Pharmacol. 1998 Mar;357(3):344-50.

PMID:
9550308
20.
21.

Differential induction of mRNA expression of cytochromes P450 (CYP2B1 and CYP1A1/2) by metyrapone in primary rat hepatocyte cultures.

Aubrecht J, Hirsch-Ernst KI, Foth H, Kahl GF, Höhne MW.

Res Commun Mol Pathol Pharmacol. 1996 Oct;94(1):47-61.

PMID:
8948014
22.

Modulation of P-glycoprotein and mdr1b mRNA expression by growth factors in primary rat hepatocyte culture.

Hirsch-Ernst KI, Ziemann C, Schmitz-Salue C, Foth H, Kahl GF.

Biochem Biophys Res Commun. 1995 Oct 4;215(1):179-85.

PMID:
7575588
23.

Induction of cytochrome P-4502B1-related mouse cytochrome P-450 and regulation of its expression by epidermal growth factor/transforming growth factor alpha in primary hepatocyte culture.

Aubrecht J, Hirsch-Ernst KI, Becker-Rabbenstein V, Kahl GF, Taniguchi H, Höhne MW.

Biochem Pharmacol. 1995 Sep 7;50(6):781-5.

PMID:
7575638
24.

[Ethanol ingestion following Antabus overdose: acetaldehyde-induced cardiological emergency].

Becker J, Desel H, Schuster HP, Kahl GF.

Ther Umsch. 1995 Mar;52(3):183-7. German.

PMID:
7725274
25.
26.

Regulation of fibronectin mRNA expression in primary hepatocytes in response to EGF and phenobarbital.

Aubrecht J, Kahl GF, Höhne MW.

Biochem Biophys Res Commun. 1993 Feb 15;190(3):1023-8.

PMID:
8382483
27.

Carcinogen-induced diploid hepatocytes: sensitive target cells for transformation by mutated c-Ha-ras oncogene.

Höhne MW, Zieroth S, Veser U, Kahl GF, Schwarz LR.

Mol Carcinog. 1993;7(3):180-9.

PMID:
8489713
28.

Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma.

Höhne MW, Halatsch ME, Kahl GF, Weinel RJ.

Cancer Res. 1992 May 1;52(9):2616-9.

29.

Increased cotinine elimination and cotinine-N-oxide formation by phenobarbital induction in rat and mouse.

Foth H, Aubrecht J, Höhne M, Walther UI, Kahl GF.

Clin Investig. 1992 Mar-Apr;70(3-4):175-81.

PMID:
1521032
30.

Nicotine metabolism in isolated perfused lung and liver of phenobarbital- and benzoflavone-treated rats.

Foth H, Looschen H, Neurath H, Kahl GF.

Arch Toxicol. 1991;65(1):68-72.

PMID:
2043053
31.

Kinetics of melphalan leakage during hyperthermic isolation perfusion in melanoma of the limb.

Rauschecker HF, Foth H, Michaelis HC, Horst F, Gatzemeier W, Willenbrock C, Voth E, Kahl GF.

Cancer Chemother Pharmacol. 1991;27(5):379-84.

PMID:
1998997
33.

Pulmonary elimination and metabolism of 5-fluoro-2'-deoxyuridine in isolated perfused rat lung and lung slices.

Foth H, Hellkamp J, Kunellis EM, Kahl GF.

Drug Metab Dispos. 1990 Nov-Dec;18(6):1011-7.

PMID:
1981506
34.

Regulation of cytochrome P-450 CYPIA1 gene expression and proto-oncogene expression by growth factors in primary hepatocytes.

Höhne M, Becker-Rabbenstein V, Kahl GF, Taniguchi H.

FEBS Lett. 1990 Oct 29;273(1-2):219-22.

35.

Increased hepatic nicotine elimination after phenobarbital induction in the conscious rat.

Foth H, Walther UI, Kahl GF.

Toxicol Appl Pharmacol. 1990 Sep 15;105(3):382-92.

PMID:
2237913
36.

Nonlinear elimination kinetics of 5-fluoro-2'-deoxyuridine in isolated perfused rat liver and isolated hepatocytes.

Foth H, Kunellis EM, Müseler T, Kahl GF.

J Pharmacol Exp Ther. 1990 Aug;254(2):427-32.

PMID:
2143535
37.

Sensitive determination of bupivacaine in human plasma by high-performance liquid chromatography.

Michaelis HC, Geng WP, Kahl GF, Foth H.

J Chromatogr. 1990 Apr 27;527(1):201-7. No abstract available.

PMID:
2365781
38.

Pharmacokinetics of low doses of benzo[a]pyrene in the rat.

Foth H, Kahl R, Kahl GF.

Food Chem Toxicol. 1988 Jan;26(1):45-51.

PMID:
3345969
39.
40.

Eightfold induction of nicotine elimination in perfused rat liver by pretreatment with phenobarbital.

Rüdell U, Foth H, Kahl GF.

Biochem Biophys Res Commun. 1987 Oct 14;148(1):192-8.

PMID:
3675573
41.

Metabolism of benzo[a]pyrene in the combined rat liver--lung perfusion system.

Mollière M, Foth H, Kahl R, Kahl GF.

Toxicology. 1987 Aug;45(2):143-54.

PMID:
3603580
42.

Comparison of benzo(a)pyrene metabolism in isolated perfused rat lung and liver.

Mollière M, Foth H, Kahl R, Kahl GF.

Arch Toxicol. 1987 Jun;60(4):270-7.

PMID:
3632352
43.

Determination of 5-fluoro-2'-deoxyuridine in human plasma by high-performance liquid chromatography with pre-column fluorimetric derivatization.

Michaelis HC, Foth H, Kahl GF.

J Chromatogr. 1987 Apr 24;416(1):176-82. No abstract available.

PMID:
2954992
44.

Covalent binding of benzo(a)pyrene in perfused rat lung following systemic and intratracheal administration.

Foth H, Mollière M, Kahl R, Jähnchen E, Kahl GF.

Drug Metab Dispos. 1984 Nov-Dec;12(6):760-6.

PMID:
6150827
45.
46.

Influence of gallic acid esters on drug-metabolizing enzymes of rat liver.

Depner M, Kahl GF, Kahl R.

Food Chem Toxicol. 1982 Oct;20(5):507-11.

PMID:
6890504
47.

Similar level of metabolic activation of benzo(a)pyrene in perfused rat lung and liver and protection of lung by liver in a combined perfusion system.

Klaus E, Foth H, Kahl R, Kahl GF.

Biochem Biophys Res Commun. 1982 Mar 30;105(2):596-602. No abstract available.

PMID:
6178407
48.

Clotrimazole as an inhibitor of benzo[a]pyrene metabolite-DNA adduct formation in vitro and of microsomal mono-oxygenase activity.

Kahl R, Friederici DE, Kahl GF, Ritter W, Krebs R.

Drug Metab Dispos. 1980 Jul-Aug;8(4):191-6.

PMID:
6105049
49.

Circadian rhythm of the inhibitory effect of actinomycin D on cytochrome P-448 induction by 3-methylcholanthrene.

Beil W, Kahl R, Kahl GF.

Biochem Pharmacol. 1980 Apr 15;29(8):1201-4. No abstract available.

PMID:
7387737
50.

NADPH-cytochrome P-450 reductase: preferential inhibition by ellipticine and other type II compounds having little effect on NADPH-cytochrome c reductase.

Guenthner TM, Kahl GF, Nebert DW.

Biochem Pharmacol. 1980 Jan 1;29(1):89-95. No abstract available.

PMID:
6767479

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