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Obesity and metabolic syndrome in COPD: is exercise the answer?

James BD, Jones AV, Trethewey RE, Evans RA.

Chron Respir Dis. 2017 Jan 1:1479972317736294. doi: 10.1177/1479972317736294. [Epub ahead of print]


GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.

Jones AV, Tilley M, Gutteridge A, Hyde C, Nagle M, Ziemek D, Gorman D, Fauman EB, Chen X, Miller MR, Tian C, Hu Y, Hinds DA, Cox P, Scollen S.

Hum Mol Genet. 2017 Apr 1;26(7):1391-1406. doi: 10.1093/hmg/ddx036.


Gas-phase detection of solid-state fission product complexes for post-detonation nuclear forensic analysis.

Stratz SA, Jones SA, Oldham CJ, Mullen AD, Jones AV, Auxier JD 2nd, Hall HL.

J Radioanal Nucl Chem. 2016;310(3):1273-1276. Epub 2016 Jun 27.


Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13.2, near the nerve growth factor locus.

Jones AV, Hockley JR, Hyde C, Gorman D, Sredic-Rhodes A, Bilsland J, McMurray G, Furlotte NA, Hu Y, Hinds DA, Cox PJ, Scollen S.

Pain. 2016 Nov;157(11):2571-2581.


Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis.

McIntosh AM, Hall LS, Zeng Y, Adams MJ, Gibson J, Wigmore E, Hagenaars SP, Davies G, Fernandez-Pujals AM, Campbell AI, Clarke TK, Hayward C, Haley CS, Porteous DJ, Deary IJ, Smith DJ, Nicholl BI, Hinds DA, Jones AV, Scollen S, Meng W, Smith BH, Hocking LJ.

PLoS Med. 2016 Aug 16;13(8):e1002090. doi: 10.1371/journal.pmed.1002090. eCollection 2016 Aug.


Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity.

Burg AR, Quigley L, Jones AV, O'Connor GM, Boelte K, McVicar DW, Orr SJ.

Springerplus. 2016 Jun 21;5(1):815. doi: 10.1186/s40064-016-2501-1. eCollection 2016.


IL-27 Induced by Select Candida spp. via TLR7/NOD2 Signaling and IFN-β Production Inhibits Fungal Clearance.

Patin EC, Jones AV, Thompson A, Clement M, Liao CT, Griffiths JS, Wallace LE, Bryant CE, Lang R, Rosenstiel P, Humphreys IR, Taylor PR, Jones GW, Orr SJ.

J Immunol. 2016 Jul 1;197(1):208-21. doi: 10.4049/jimmunol.1501204. Epub 2016 Jun 3.


IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2.

Xu R, Sun HF, Williams DW, Jones AV, Al-Hussaini A, Song B, Wei XQ.

J Immunol Res. 2015;2015:328146. doi: 10.1155/2015/328146. Epub 2015 Jun 3.


Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus.

Chase A, Leung W, Tapper W, Jones AV, Knoops L, Rasi C, Forsberg LA, Guglielmelli P, Zoi K, Hall V, Chiecchio L, Eder-Azanza L, Bryant C, Lannfelt L, Docherty L, White HE, Score J, Mackay DJ, Vannucchi AM, Dumanski JP, Cross NC.

Leukemia. 2015 Oct;29(10):2069-74. doi: 10.1038/leu.2015.130. Epub 2015 May 20.


Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms.

Tapper W, Jones AV, Kralovics R, Harutyunyan AS, Zoi K, Leung W, Godfrey AL, Guglielmelli P, Callaway A, Ward D, Aranaz P, White HE, Waghorn K, Lin F, Chase A, Baxter EJ, Maclean C, Nangalia J, Chen E, Evans P, Short M, Jack A, Wallis L, Oscier D, Duncombe AS, Schuh A, Mead AJ, Griffiths M, Ewing J, Gale RE, Schnittger S, Haferlach T, Stegelmann F, Döhner K, Grallert H, Strauch K, Tanaka T, Bandinelli S, Giannopoulos A, Pieri L, Mannarelli C, Gisslinger H, Barosi G, Cazzola M, Reiter A, Harrison C, Campbell P, Green AR, Vannucchi A, Cross NC.

Nat Commun. 2015 Apr 7;6:6691. doi: 10.1038/ncomms7691.


Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals.

Score J, Chase A, Forsberg LA, Feng L, Waghorn K, Jones AV, Rasi C, Linch DC, Dumanski JP, Gale RE, Cross NC.

Leukemia. 2015 Jul;29(7):1600-2. doi: 10.1038/leu.2015.13. Epub 2015 Jan 28. No abstract available.


Evaluation of methods to detect CALR mutations in myeloproliferative neoplasms.

Jones AV, Ward D, Lyon M, Leung W, Callaway A, Chase A, Dent CL, White HE, Drexler HG, Nangalia J, Mattocks C, Cross NC.

Leuk Res. 2015 Jan;39(1):82-7. doi: 10.1016/j.leukres.2014.11.019. Epub 2014 Nov 29.


Solitary fibrous tumour of the cheek: An unusual presentation of a rare soft tissue tumour.

Greenall CJ, Jones JL, Jones AV, Drage NA, Bhatia S, Hourihan MD.

Ultrasound. 2014 Nov;22(4):236-9. doi: 10.1177/1742271X14554145. Epub 2014 Oct 2.


Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.

Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O'Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJP, Harrison CN, Cross NCP, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR.

N Engl J Med. 2013 Dec 19;369(25):2391-2405. doi: 10.1056/NEJMoa1312542. Epub 2013 Dec 10.


JAK2V617F allele burden is reduced by busulfan therapy: a new observation using an old drug.

Kuriakose ET, Gjoni S, Wang YL, Baumann R, Jones AV, Cross NC, Silver RT.

Haematologica. 2013 Nov;98(11):e135-7. doi: 10.3324/haematol.2013.087742. No abstract available.


ADAM 10 is over expressed in oral squamous cell carcinoma and contributes to invasive behaviour through a functional association with αvβ6 integrin.

Jones AV, Lambert DW, Speight PM, Whawell SA.

FEBS Lett. 2013 Nov 1;587(21):3529-34. doi: 10.1016/j.febslet.2013.09.010. Epub 2013 Sep 18.


Inherited predisposition to myeloproliferative neoplasms.

Jones AV, Cross NC.

Ther Adv Hematol. 2013 Aug;4(4):237-53. doi: 10.1177/2040620713489144.


Why do we see JAK2 exon 12 mutations in myeloproliferative neoplasms?

Vorechovsky I, Jones AV, Cross NC.

Leukemia. 2013 Sep;27(9):1930-2. doi: 10.1038/leu.2013.85. Epub 2013 Mar 20. No abstract available.


JAK2V617F allele burden, JAK2 46/1 haplotype and clinical features of Chinese with myeloproliferative neoplasms.

Wang J, Xu Z, Liu L, Gale RP, Cross NC, Jones AV, Qin T, Ai X, Xu J, Zhang T, Sun X, Li Q, Zhang P, Zhang Y, Xiao Z.

Leukemia. 2013 Aug;27(8):1763-7. doi: 10.1038/leu.2013.21. Epub 2013 Jan 22. No abstract available.


Decrease in JAK2 V617F allele burden is not a prerequisite to clinical response in patients with polycythemia vera.

Kuriakose E, Vandris K, Wang YL, Chow W, Jones AV, Christos P, Cross NC, Silver RT.

Haematologica. 2012 Apr;97(4):538-42. doi: 10.3324/haematol.2011.053348. Epub 2011 Nov 18.


Histopathological features that predict the recurrence of odontogenic keratocysts.

Cottom HE, Bshena FI, Speight PM, Craig GT, Jones AV.

J Oral Pathol Med. 2012 May;41(5):408-14. doi: 10.1111/j.1600-0714.2011.01113.x. Epub 2011 Nov 16.


Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms.

Score J, Hidalgo-Curtis C, Jones AV, Winkelmann N, Skinner A, Ward D, Zoi K, Ernst T, Stegelmann F, Döhner K, Chase A, Cross NC.

Blood. 2012 Feb 2;119(5):1208-13. doi: 10.1182/blood-2011-07-367243. Epub 2011 Nov 3.


Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma.

Colley HE, Hearnden V, Jones AV, Weinreb PH, Violette SM, Macneil S, Thornhill MH, Murdoch C.

Br J Cancer. 2011 Nov 8;105(10):1582-92. doi: 10.1038/bjc.2011.403. Epub 2011 Oct 11.


EZH2 mutational status predicts poor survival in myelofibrosis.

Guglielmelli P, Biamonte F, Score J, Hidalgo-Curtis C, Cervantes F, Maffioli M, Fanelli T, Ernst T, Winkelman N, Jones AV, Zoi K, Reiter A, Duncombe A, Villani L, Bosi A, Barosi G, Cross NC, Vannucchi AM.

Blood. 2011 Nov 10;118(19):5227-34. doi: 10.1182/blood-2011-06-363424. Epub 2011 Sep 14.


MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1.

Hunt S, Jones AV, Hinsley EE, Whawell SA, Lambert DW.

FEBS Lett. 2011 Jan 3;585(1):187-92. doi: 10.1016/j.febslet.2010.11.038. Epub 2010 Nov 27.


Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus.

Venegas-Pont M, Manigrasso MB, Grifoni SC, LaMarca BB, Maric C, Racusen LC, Glover PH, Jones AV, Drummond HA, Ryan MJ.

Hypertension. 2010 Oct;56(4):643-9. doi: 10.1161/HYPERTENSIONAHA.110.157685. Epub 2010 Aug 9.


JAK2(V617F) allele burden in polycythemia vera correlates with grade of myelofibrosis, but is not substantially affected by therapy.

Silver RT, Vandris K, Wang YL, Adriano F, Jones AV, Christos PJ, Cross NC.

Leuk Res. 2011 Feb;35(2):177-82. doi: 10.1016/j.leukres.2010.06.017. Epub 2010 Jul 22.


Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders.

Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, Waghorn K, Zoi K, Ross FM, Reiter A, Hochhaus A, Drexler HG, Duncombe A, Cervantes F, Oscier D, Boultwood J, Grand FH, Cross NC.

Nat Genet. 2010 Aug;42(8):722-6. doi: 10.1038/ng.621. Epub 2010 Jul 4.


No association between myeloproliferative neoplasms and the Crohn's disease-associated STAT3 predisposition SNP rs744166.

Jones AV, Cross NC.

Haematologica. 2010 Jul;95(7):1226-7. doi: 10.3324/haematol.2010.023390. No abstract available. Erratum in: Haematologica. 2010 Dec;95(12):2166.


The myeloproliferative neoplasm-associated JAK2 46/1 haplotype is not overrepresented in chronic myelogenous leukemia.

Spolverini A, Jones AV, Hochhaus A, Pieri L, Cross NC, Vannucchi AM.

Ann Hematol. 2011 Mar;90(3):365-6. doi: 10.1007/s00277-010-1009-y. Epub 2010 Jun 16. No abstract available.


The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms.

Jones AV, Campbell PJ, Beer PA, Schnittger S, Vannucchi AM, Zoi K, Percy MJ, McMullin MF, Scott LM, Tapper W, Silver RT, Oscier D, Harrison CN, Grallert H, Kisialiou A, Strike P, Chase AJ, Green AR, Cross NC.

Blood. 2010 Jun 3;115(22):4517-23. doi: 10.1182/blood-2009-08-236448. Epub 2010 Mar 19.


Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats.

Sartori-Valinotti JC, Venegas-Pont MR, Lamarca BB, Romero DG, Yanes LL, Racusen LC, Jones AV, Ryan MJ, Reckelhoff JF.

Steroids. 2010 Nov;75(11):794-9. doi: 10.1016/j.steroids.2009.10.010. Epub 2009 Oct 31.


JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms.

Jones AV, Chase A, Silver RT, Oscier D, Zoi K, Wang YL, Cario H, Pahl HL, Collins A, Reiter A, Grand F, Cross NC.

Nat Genet. 2009 Apr;41(4):446-9. doi: 10.1038/ng.334. Epub 2009 Mar 15.


Rosiglitazone decreases blood pressure and renal injury in a female mouse model of systemic lupus erythematosus.

Venegas-Pont M, Sartori-Valinotti JC, Maric C, Racusen LC, Glover PH, McLemore GR Jr, Jones AV, Reckelhoff JF, Ryan MJ.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1282-9. doi: 10.1152/ajpregu.90992.2008. Epub 2009 Feb 4.


Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones.

Beer PA, Jones AV, Bench AJ, Goday-Fernandez A, Boyd EM, Vaghela KJ, Erber WN, Odeh B, Wright C, McMullin MF, Cullis J, Huntly BJ, Harrison CN, Cross NC, Green AR.

Br J Haematol. 2009 Mar;144(6):904-8. doi: 10.1111/j.1365-2141.2008.07560.x. Epub 2009 Jan 16.


No evidence for increased prevalence of JAK2 V617F in women with a history of recurrent miscarriage.

Dahabreh IJ, Jones AV, Voulgarelis M, Giannouli S, Zoi C, Alafakis-Tzannatos C, Varla-Leftherioti M, Moutsopoulos HM, Loukopoulos D, Fotiou S, Cross NC, Zoi K.

Br J Haematol. 2009 Mar;144(5):802-3. doi: 10.1111/j.1365-2141.2008.07510.x. Epub 2008 Nov 17. No abstract available.


Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions.

Score J, Walz C, Jovanovic JV, Jones AV, Waghorn K, Hidalgo-Curtis C, Lin F, Grimwade D, Grand F, Reiter A, Cross NC.

Leukemia. 2009 Feb;23(2):332-9. doi: 10.1038/leu.2008.309. Epub 2008 Nov 6.


Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.

Jones AV, Cross NC, White HE, Green AR, Scott LM.

Haematologica. 2008 Oct;93(10):1560-4. doi: 10.3324/haematol.12883. Epub 2008 Aug 12.


The range and demographics of salivary gland tumours diagnosed in a UK population.

Jones AV, Craig GT, Speight PM, Franklin CD.

Oral Oncol. 2008 Apr;44(4):407-17. Epub 2007 Sep 6.


JAK2-V617F mutation in a patient with Philadelphia-chromosome-positive chronic myeloid leukaemia.

Krämer A, Reiter A, Kruth J, Erben P, Hochhaus A, Müller M, Cross NC, Jones AV, Ho AD, Hensel M.

Lancet Oncol. 2007 Jul;8(7):658-60. No abstract available.


No evidence for amplification of V617F JAK2 in myeloproliferative disorders.

Jones AV, Bunyan DJ, Cross NC.

Leukemia. 2007 Dec;21(12):2561-3. Epub 2007 Jul 5. No abstract available.


Fine needle aspiration cytology as an additional tool in the diagnosis of odontogenic keratocyst.

Vargas PA, da Cruz Perez DE, Mata GM, de Almeida OP, Jones AV, Gerhard R.

Cytopathology. 2007 Dec;18(6):361-6. Epub 2007 Mar 27.


FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.

Crescenzi B, Chase A, Starza RL, Beacci D, Rosti V, Gallì A, Specchia G, Martelli MF, Vandenberghe P, Cools J, Jones AV, Cross NC, Marynen P, Mecucci C.

Leukemia. 2007 Mar;21(3):397-402. Epub 2007 Jan 11.


Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period.

Jones AV, Craig GT, Franklin CD.

J Oral Pathol Med. 2006 Sep;35(8):500-7.


An analysis of oral and maxillofacial pathology found in adults over a 30-year period.

Jones AV, Franklin CD.

J Oral Pathol Med. 2006 Aug;35(7):392-401.


A survey of oral and maxillofacial pathology specimens submitted by general dental practitioners over a 30-year period.

Franklin CD, Jones AV.

Br Dent J. 2006 Apr 22;200(8):447-50; discussion 443.


Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity.

Chung KF, Hew M, Score J, Jones AV, Reiter A, Cross NC, Bain BJ.

Eur Respir J. 2006 Jan;27(1):230-2.


An analysis of oral and maxillofacial pathology found in children over a 30-year period.

Jones AV, Franklin CD.

Int J Paediatr Dent. 2006 Jan;16(1):19-30.


Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha.

Jones AV, Silver RT, Waghorn K, Curtis C, Kreil S, Zoi K, Hochhaus A, Oscier D, Metzgeroth G, Lengfelder E, Reiter A, Chase AJ, Cross NC.

Blood. 2006 Apr 15;107(8):3339-41. Epub 2005 Dec 13.

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