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Items: 1 to 50 of 292


Glial Tissue Mechanics and Mechanosensing by Glial Cells.

Pogoda K, Janmey PA.

Front Cell Neurosci. 2018 Feb 21;12:25. doi: 10.3389/fncel.2018.00025. eCollection 2018. Review.


Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates.

Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, Shenoy VB.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2686-E2695. doi: 10.1073/pnas.1716620115. Epub 2018 Mar 5.


Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics.

Bucki R, Durnaś B, Wątek M, Piktel E, Cruz K, Wolak P, Savage PB, Janmey PA.

Infect Drug Resist. 2018 Jan 11;11:77-86. doi: 10.2147/IDR.S145337. eCollection 2018.


Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation.

Charrier EE, Pogoda K, Wells RG, Janmey PA.

Nat Commun. 2018 Jan 31;9(1):449. doi: 10.1038/s41467-018-02906-9.


Soft Substrates Containing Hyaluronan Mimic the Effects of Increased Stiffness on Morphology, Motility, and Proliferation of Glioma Cells.

Pogoda K, Bucki R, Byfield FJ, Cruz K, Lee T, Marcinkiewicz C, Janmey PA.

Biomacromolecules. 2017 Oct 9;18(10):3040-3051. doi: 10.1021/acs.biomac.7b00324. Epub 2017 Sep 14.


Mechanotransduction in cancer.

Chin L, Xia Y, Discher DE, Janmey PA.

Curr Opin Chem Eng. 2016 Feb;11:77-84. doi: 10.1016/j.coche.2016.01.011. Epub 2016 Feb 16.


Biochemical and Cellular Determinants of Renal Glomerular Elasticity.

Embry AE, Mohammadi H, Niu X, Liu L, Moe B, Miller-Little WA, Lu CY, Bruggeman LA, McCulloch CA, Janmey PA, Miller RT.

PLoS One. 2016 Dec 12;11(12):e0167924. doi: 10.1371/journal.pone.0167924. eCollection 2016.


Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy.

Bae YH, Liu SL, Byfield FJ, Janmey PA, Assoian RK.

J Vis Exp. 2016 Oct 19;(116). doi: 10.3791/54630.


Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin.

Wang YH, Bucki R, Janmey PA.

Biochemistry. 2016 Jun 21;55(24):3361-9. doi: 10.1021/acs.biochem.5b01363. Epub 2016 Jun 9.


Elasticity of fibrous networks under uniaxial prestress.

Vahabi M, Sharma A, Licup AJ, van Oosten AS, Galie PA, Janmey PA, MacKintosh FC.

Soft Matter. 2016 Jun 14;12(22):5050-60. doi: 10.1039/c6sm00606j. Epub 2016 May 13.


Methods for Determining the Cellular Functions of Vimentin Intermediate Filaments.

Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD.

Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036. Epub 2015 Dec 19.


Mechanical Properties of Intermediate Filament Proteins.

Charrier EE, Janmey PA.

Methods Enzymol. 2016;568:35-57. doi: 10.1016/bs.mie.2015.09.009. Epub 2015 Nov 3.


Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening.

van Oosten AS, Vahabi M, Licup AJ, Sharma A, Galie PA, MacKintosh FC, Janmey PA.

Sci Rep. 2016 Jan 13;6:19270. doi: 10.1038/srep19270.


Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics.

Perepelyuk M, Chin L, Cao X, van Oosten A, Shenoy VB, Janmey PA, Wells RG.

PLoS One. 2016 Jan 6;11(1):e0146588. doi: 10.1371/journal.pone.0146588. eCollection 2016.


Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC.

Smith JR, Galie PA, Slochower DR, Weisshaar CL, Janmey PA, Winkelstein BA.

Biomaterials. 2016 Feb;80:96-105. doi: 10.1016/j.biomaterials.2015.11.062. Epub 2015 Dec 2.


A comparison of hyperelastic constitutive models applicable to brain and fat tissues.

Mihai LA, Chin L, Janmey PA, Goriely A.

J R Soc Interface. 2015 Sep 6;12(110):0486. doi: 10.1098/rsif.2015.0486.


Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection.

Bucki R, Niemirowicz K, Wnorowska U, Byfield FJ, Piktel E, Wątek M, Janmey PA, Savage PB.

Antimicrob Agents Chemother. 2015 Oct;59(10):6274-82. doi: 10.1128/AAC.00653-15. Epub 2015 Jul 27.


Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix.

Mohammadi H, Pinto VI, Wang Y, Hinz B, Janmey PA, McCulloch CA.

J Invest Dermatol. 2015 Nov;135(11):2852-2861. doi: 10.1038/jid.2015.251. Epub 2015 Jul 2.


Relationship of and cross-talk between physical and biologic properties of the glomerulus.

Miller RT, Janmey PA.

Curr Opin Nephrol Hypertens. 2015 Jul;24(4):393-400. doi: 10.1097/MNH.0000000000000138. Review.


Polyelectrolyte-mediated increase of biofilm mass formation.

Bucki R, Niemirowicz K, Wnorowska U, Wątek M, Byfield FJ, Cruz K, Wróblewska M, Janmey PA.

BMC Microbiol. 2015 Jun 6;15:117. doi: 10.1186/s12866-015-0457-x.


Synthesis and structure-activity relationships of novel cationic lipids with anti-inflammatory and antimicrobial activities.

Myint M, Bucki R, Janmey PA, Diamond SL.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2837-43. doi: 10.1016/j.bmcl.2015.04.104. Epub 2015 May 11.


The (dys)functional extracellular matrix.

Freedman BR, Bade ND, Riggin CN, Zhang S, Haines PG, Ong KL, Janmey PA.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):3153-64. doi: 10.1016/j.bbamcr.2015.04.015. Epub 2015 Apr 27. Review.


Physical chemistry and membrane properties of two phosphatidylinositol bisphosphate isomers.

Slochower DR, Wang YH, Radhakrishnan R, Janmey PA.

Phys Chem Chem Phys. 2015 May 21;17(19):12608-15. doi: 10.1039/c5cp00862j.


Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling.

Arora PD, Wang Y, Bresnick A, Janmey PA, McCulloch CA.

Mol Biol Cell. 2015 Jun 15;26(12):2279-97. doi: 10.1091/mbc.E14-11-1536. Epub 2015 Apr 15.


Bactericidal activities of cathelicidin LL-37 and select cationic lipids against the hypervirulent Pseudomonas aeruginosa strain LESB58.

Wnorowska U, Niemirowicz K, Myint M, Diamond SL, Wróblewska M, Savage PB, Janmey PA, Bucki R.

Antimicrob Agents Chemother. 2015 Jul;59(7):3808-15. doi: 10.1128/AAC.00421-15. Epub 2015 Apr 13.


Compression stiffening of brain and its effect on mechanosensing by glioma cells.

Pogoda K, Chin L, Georges PC, Byfield FJ, Bucki R, Kim R, Weaver M, Wells RG, Marcinkiewicz C, Janmey PA.

New J Phys. 2014 Jul;16:075002.


Enhancement of Pulmozyme activity in purulent sputum by combination with poly-aspartic acid or gelsolin.

Bucki R, Cruz K, Pogoda K, Eggert A, Chin L, Ferrin M, Imbesi G, Hadjiliadis D, Janmey PA.

J Cyst Fibros. 2015 Sep;14(5):587-93. doi: 10.1016/j.jcf.2015.02.001. Epub 2015 Feb 13.


Application of multiple levels of fluid shear stress to endothelial cells plated on polyacrylamide gels.

Galie PA, van Oosten A, Chen CS, Janmey PA.

Lab Chip. 2015 Feb 21;15(4):1205-12. doi: 10.1039/c4lc01236d.


Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis.

Kułakowska A, Byfield FJ, Zendzian-Piotrowska M, Zajkowska JM, Drozdowski W, Mroczko B, Janmey PA, Bucki R.

J Neuroinflammation. 2014 Nov 25;11:193. doi: 10.1186/s12974-014-0193-4.


Clamping down on tumor proliferation.

Chalut KJ, Janmey PA.

Biophys J. 2014 Oct 21;107(8):1775-6. doi: 10.1016/j.bpj.2014.09.004. No abstract available.


Inelastic behaviour of collagen networks in cell-matrix interactions and mechanosensation.

Mohammadi H, Arora PD, Simmons CA, Janmey PA, McCulloch CA.

J R Soc Interface. 2015 Jan 6;12(102):20141074. doi: 10.1098/rsif.2014.1074.


Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae.

Thomson DD, Wehmeier S, Byfield FJ, Janmey PA, Caballero-Lima D, Crossley A, Brand AC.

Cell Microbiol. 2015 Mar;17(3):342-54. doi: 10.1111/cmi.12369. Epub 2014 Nov 25.


Mechanically stimulated contraction of engineered cardiac constructs using a microcantilever.

Galie PA, Byfield FJ, Chen CS, Kresh JY, Janmey PA.

IEEE Trans Biomed Eng. 2015 Feb;62(2):438-42. doi: 10.1109/TBME.2014.2357778. Epub 2014 Sep 15.


Vimentin enhances cell elastic behavior and protects against compressive stress.

Mendez MG, Restle D, Janmey PA.

Biophys J. 2014 Jul 15;107(2):314-323. doi: 10.1016/j.bpj.2014.04.050.


Fluid shear stress threshold regulates angiogenic sprouting.

Galie PA, Nguyen DH, Choi CK, Cohen DM, Janmey PA, Chen CS.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):7968-73. doi: 10.1073/pnas.1310842111. Epub 2014 May 19.


Polyelectrolyte properties of filamentous biopolymers and their consequences in biological fluids.

Janmey PA, Slochower DR, Wang YH, Wen Q, Cēbers A.

Soft Matter. 2014 Mar 14;10(10):1439-49. doi: 10.1039/c3sm50854d. Review.


Cytoplasmic transport: bacteria turn to glass unless kicked.

Janmey PA, MacKintosh FC.

Curr Biol. 2014 Mar 17;24(6):R226-8. doi: 10.1016/j.cub.2014.02.018.


Counterion-mediated pattern formation in membranes containing anionic lipids.

Slochower DR, Wang YH, Tourdot RW, Radhakrishnan R, Janmey PA.

Adv Colloid Interface Sci. 2014 Jun;208:177-88. doi: 10.1016/j.cis.2014.01.016. Epub 2014 Jan 30. Review.


Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.

Del Campo CM, Mishra AK, Wang YH, Roy CR, Janmey PA, Lambright DG.

Structure. 2014 Mar 4;22(3):397-408. doi: 10.1016/j.str.2013.12.018. Epub 2014 Feb 13.


Counterion-mediated cluster formation by polyphosphoinositides.

Wang YH, Slochower DR, Janmey PA.

Chem Phys Lipids. 2014 Sep;182:38-51. doi: 10.1016/j.chemphyslip.2014.01.001. Epub 2014 Jan 15. Review.


Salmon and human thrombin differentially regulate radicular pain, glial-induced inflammation and spinal neuronal excitability through protease-activated receptor-1.

Smith JR, Syre PP, Oake SA, Nicholson KJ, Weisshaar CL, Cruz K, Bucki R, Baumann BC, Janmey PA, Winkelstein BA.

PLoS One. 2013 Nov 20;8(11):e80006. doi: 10.1371/journal.pone.0080006. eCollection 2013.


Lateral boundary mechanosensing by adherent cells in a collagen gel system.

Mohammadi H, Janmey PA, McCulloch CA.

Biomaterials. 2014 Jan;35(4):1138-49. doi: 10.1016/j.biomaterials.2013.10.059. Epub 2013 Nov 8.


Substrate stiffness regulates solubility of cellular vimentin.

Murray ME, Mendez MG, Janmey PA.

Mol Biol Cell. 2014 Jan;25(1):87-94. doi: 10.1091/mbc.E13-06-0326. Epub 2013 Oct 30.


Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA.

Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016/j.biomaterials.2013.09.066. Epub 2013 Oct 10.


From tissue mechanics to transcription factors.

Janmey PA, Wells RG, Assoian RK, McCulloch CA.

Differentiation. 2013 Oct;86(3):112-20. doi: 10.1016/j.diff.2013.07.004. Epub 2013 Aug 20. Review.


Quantum and all-atom molecular dynamics simulations of protonation and divalent ion binding to phosphatidylinositol 4,5-bisphosphate (PIP2).

Slochower DR, Huwe PJ, Radhakrishnan R, Janmey PA.

J Phys Chem B. 2013 Jul 18;117(28):8322-9. doi: 10.1021/jp401414y. Epub 2013 Jul 3.


Effects of non-linearity on cell-ECM interactions.

Wen Q, Janmey PA.

Exp Cell Res. 2013 Oct 1;319(16):2481-9. doi: 10.1016/j.yexcr.2013.05.017. Epub 2013 Jun 5. Review.


Mechanics in neuronal development and repair.

Franze K, Janmey PA, Guck J.

Annu Rev Biomed Eng. 2013;15:227-51. doi: 10.1146/annurev-bioeng-071811-150045. Epub 2013 May 3. Review.


Extremely charged and incredibly soft: physical characterization of the pericellular matrix.

van Oosten AS, Janmey PA.

Biophys J. 2013 Mar 5;104(5):961-3. doi: 10.1016/j.bpj.2013.01.035. No abstract available.


Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury.

Perepelyuk M, Terajima M, Wang AY, Georges PC, Janmey PA, Yamauchi M, Wells RG.

Am J Physiol Gastrointest Liver Physiol. 2013 Mar 15;304(6):G605-14. doi: 10.1152/ajpgi.00222.2012. Epub 2013 Jan 17.

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