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Estimating genetic kin relationships in prehistoric populations.

Monroy Kuhn JM, Jakobsson M, Günther T.

PLoS One. 2018 Apr 23;13(4):e0195491. doi: 10.1371/journal.pone.0195491. eCollection 2018.


Four millennia of Iberian biomolecular prehistory illustrate the impact of prehistoric migrations at the far end of Eurasia.

Valdiosera C, Günther T, Vera-Rodríguez JC, Ureña I, Iriarte E, Rodríguez-Varela R, Simões LG, Martínez-Sánchez RM, Svensson EM, Malmström H, Rodríguez L, Bermúdez de Castro JM, Carbonell E, Alday A, Hernández Vera JA, Götherström A, Carretero JM, Arsuaga JL, Smith CI, Jakobsson M.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3428-3433. doi: 10.1073/pnas.1717762115. Epub 2018 Mar 12.


Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis.

Tainio K, Athanasiou A, Tikkinen KAO, Aaltonen R, Cárdenas J, Hernándes, Glazer-Livson S, Jakobsson M, Joronen K, Kiviharju M, Louvanto K, Oksjoki S, Tähtinen R, Virtanen S, Nieminen P, Kyrgiou M, Kalliala I.

BMJ. 2018 Feb 27;360:k499. doi: 10.1136/bmj.k499. Review.


Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation.

Jakobsson ME, Małecki J, Falnes PØ.

RNA Biol. 2018 Mar 9:1-6. doi: 10.1080/15476286.2018.1440875. [Epub ahead of print]


Identification of FAM173B as a protein methyltransferase promoting chronic pain.

Willemen HLDM, Kavelaars A, Prado J, Maas M, Versteeg S, Nellissen LJJ, Tromp J, Gonzalez Cano R, Zhou W, Jakobsson ME, Małecki J, Posthuma G, Habib AM, Heijnen CJ, Falnes PØ, Eijkelkamp N.

PLoS Biol. 2018 Feb 14;16(2):e2003452. doi: 10.1371/journal.pbio.2003452. eCollection 2018 Feb.


Patterns of variation in cis-regulatory regions: examining evidence of purifying selection.

Naidoo T, Sjödin P, Schlebusch C, Jakobsson M.

BMC Genomics. 2018 Jan 26;19(1):95. doi: 10.1186/s12864-017-4422-y.


Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Günther T, Malmström H, Svensson EM, Omrak A, Sánchez-Quinto F, Kılınç GM, Krzewińska M, Eriksson G, Fraser M, Edlund H, Munters AR, Coutinho A, Simões LG, Vicente M, Sjölander A, Jansen Sellevold B, Jørgensen R, Claes P, Shriver MD, Valdiosera C, Netea MG, Apel J, Lidén K, Skar B, Storå J, Götherström A, Jakobsson M.

PLoS Biol. 2018 Jan 9;16(1):e2003703. doi: 10.1371/journal.pbio.2003703. eCollection 2018 Jan.


BedMachine v3: Complete Bed Topography and Ocean Bathymetry Mapping of Greenland From Multibeam Echo Sounding Combined With Mass Conservation.

Morlighem M, Williams CN, Rignot E, An L, Arndt JE, Bamber JL, Catania G, Chauché N, Dowdeswell JA, Dorschel B, Fenty I, Hogan K, Howat I, Hubbard A, Jakobsson M, Jordan TM, Kjeldsen KK, Millan R, Mayer L, Mouginot J, Noël BPY, O'Cofaigh C, Palmer S, Rysgaard S, Seroussi H, Siegert MJ, Slabon P, Straneo F, van den Broeke MR, Weinrebe W, Wood M, Zinglersen KB.

Geophys Res Lett. 2017 Nov 16;44(21):11051-11061. doi: 10.1002/2017GL074954. Epub 2017 Nov 1.


Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low-intensity exercise with negative energy balance.

Moberg M, Hendo G, Jakobsson M, Mattsson CM, Ekblom-Bak E, Flockhart M, Pontén M, Söderlund K, Ekblom B.

Physiol Rep. 2017 Dec;5(23). doi: 10.14814/phy2.13518.


Risk of preterm birth in women with cervical intraepithelial neoplasia grade one: a population-based cohort study.

Heinonen A, Gissler M, Paavonen J, Tapper AM, Jakobsson M.

Acta Obstet Gynecol Scand. 2018 Feb;97(2):135-141. doi: 10.1111/aogs.13256. Epub 2017 Dec 1.


Acoustic Mapping of Thermohaline Staircases in the Arctic Ocean.

Stranne C, Mayer L, Weber TC, Ruddick BR, Jakobsson M, Jerram K, Weidner E, Nilsson J, Gårdfeldt K.

Sci Rep. 2017 Nov 9;7(1):15192. doi: 10.1038/s41598-017-15486-3.


Genomic Analyses of Pre-European Conquest Human Remains from the Canary Islands Reveal Close Affinity to Modern North Africans.

Rodríguez-Varela R, Günther T, Krzewińska M, Storå J, Gillingwater TH, MacCallum M, Arsuaga JL, Dobney K, Valdiosera C, Jakobsson M, Götherström A, Girdland-Flink L.

Curr Biol. 2017 Nov 6;27(21):3396-3402.e5. doi: 10.1016/j.cub.2017.09.059. Epub 2017 Oct 26.


Evidence of marine ice-cliff instability in Pine Island Bay from iceberg-keel plough marks.

Wise MG, Dowdeswell JA, Jakobsson M, Larter RD.

Nature. 2017 Oct 25;550(7677):506-510. doi: 10.1038/nature24458.


Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago.

Schlebusch CM, Malmström H, Günther T, Sjödin P, Coutinho A, Edlund H, Munters AR, Vicente M, Steyn M, Soodyall H, Lombard M, Jakobsson M.

Science. 2017 Nov 3;358(6363):652-655. doi: 10.1126/science.aao6266. Epub 2017 Sep 28.


Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation.

Małecki J, Jakobsson ME, Ho AYY, Moen A, Rustan AC, Falnes PØ.

J Biol Chem. 2017 Oct 27;292(43):17950-17962. doi: 10.1074/jbc.M117.808451. Epub 2017 Sep 8.


A female Viking warrior confirmed by genomics.

Hedenstierna-Jonson C, Kjellström A, Zachrisson T, Krzewińska M, Sobrado V, Price N, Günther T, Jakobsson M, Götherström A, Storå J.

Am J Phys Anthropol. 2017 Dec;164(4):853-860. doi: 10.1002/ajpa.23308. Epub 2017 Sep 8.


Cancer risk of Lichen planus: A cohort study of 13,100 women in Finland.

Halonen P, Jakobsson M, Heikinheimo O, Riska A, Gissler M, Pukkala E.

Int J Cancer. 2018 Jan 1;142(1):18-22. doi: 10.1002/ijc.31025. Epub 2017 Sep 8.


Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.

Hollfelder N, Schlebusch CM, Günther T, Babiker H, Hassan HY, Jakobsson M.

PLoS Genet. 2017 Aug 24;13(8):e1006976. doi: 10.1371/journal.pgen.1006976. eCollection 2017 Aug.


Overall survival in Swedish patients with renal cell carcinoma treated in the period 2002 to 2012: Update of the RENCOMP study with subgroup analysis of the synchronous metastatic and elderly populations.

Lindskog M, Wahlgren T, Sandin R, Kowalski J, Jakobsson M, Lundstam S, Ljungberg B, Harmenberg U.

Urol Oncol. 2017 Sep;35(9):541.e15-541.e22. doi: 10.1016/j.urolonc.2017.05.013. Epub 2017 Jun 13.


Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.

Jakobsson ME, Malecki J, Nilges BS, Moen A, Leidel SA, Falnes PØ.

Nucleic Acids Res. 2017 Aug 21;45(14):8239-8254. doi: 10.1093/nar/gkx432.


Reply to Lazaridis and Reich: Robust model-based inference of male-biased admixture during Bronze Age migration from the Pontic-Caspian Steppe.

Goldberg A, Günther T, Rosenberg NA, Jakobsson M.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3875-E3877. doi: 10.1073/pnas.1704442114. Epub 2017 May 5. No abstract available.


Mode of first delivery and severe maternal complications in the subsequent pregnancy.

Colmorn LB, Krebs L, Klungsøyr K, Jakobsson M, Tapper AM, Gissler M, Lindqvist PG, Källen K, Gottvall K, Bordahl PE, Bjarnadóttir RI, Langhoff-Roos J.

Acta Obstet Gynecol Scand. 2017 Sep;96(9):1053-1062. doi: 10.1111/aogs.13163. Epub 2017 Jun 26.


National Rates of Uterine Rupture are not Associated with Rates of Previous Caesarean Delivery: Results from the Nordic Obstetric Surveillance Study.

Colmorn LB, Langhoff-Roos J, Jakobsson M, Tapper AM, Gissler M, Lindqvist PG, Källen K, Gottvall K, Klungsøyr K, Bøhrdahl P, Bjarnadóttir RI, Krebs L.

Paediatr Perinat Epidemiol. 2017 May;31(3):176-182. doi: 10.1111/ppe.12356. Epub 2017 Apr 20.


Adaptation to infectious disease exposure in indigenous Southern African populations.

Owers KA, Sjödin P, Schlebusch CM, Skoglund P, Soodyall H, Jakobsson M.

Proc Biol Sci. 2017 Apr 12;284(1852). pii: 20170226. doi: 10.1098/rspb.2017.0226.


Late Danubian mitochondrial genomes shed light into the Neolithisation of Central Europe in the 5th millennium BC.

Chyleński M, Juras A, Ehler E, Malmström H, Piontek J, Jakobsson M, Marciniak A, Dabert M.

BMC Evol Biol. 2017 Mar 16;17(1):80. doi: 10.1186/s12862-017-0924-0.


Ancient X chromosomes reveal contrasting sex bias in Neolithic and Bronze Age Eurasian migrations.

Goldberg A, Günther T, Rosenberg NA, Jakobsson M.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2657-2662. doi: 10.1073/pnas.1616392114. Epub 2017 Feb 21.


Pain Sensation During Colposcopy and Cervical Biopsy, With or Without Local Anesthesia: A Randomized Trial.

Kiviharju M, Kalliala I, Nieminen P, Dyba T, Riska A, Jakobsson M.

J Low Genit Tract Dis. 2017 Apr;21(2):102-107. doi: 10.1097/LGT.0000000000000292.


Lichen sclerosus and risk of cancer.

Halonen P, Jakobsson M, Heikinheimo O, Riska A, Gissler M, Pukkala E.

Int J Cancer. 2017 May 1;140(9):1998-2002. doi: 10.1002/ijc.30621. Epub 2017 Feb 10.


The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).

Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sørensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PØ.

Nucleic Acids Res. 2017 May 5;45(8):4370-4389. doi: 10.1093/nar/gkx002.


Tracing the peopling of the world through genomics.

Nielsen R, Akey JM, Jakobsson M, Pritchard JK, Tishkoff S, Willerslev E.

Nature. 2017 Jan 18;541(7637):302-310. doi: 10.1038/nature21347. Review.


Massive remobilization of permafrost carbon during post-glacial warming.

Tesi T, Muschitiello F, Smittenberg RH, Jakobsson M, Vonk JE, Hill P, Andersson A, Kirchner N, Noormets R, Dudarev O, Semiletov I, Gustafsson Ö.

Nat Commun. 2016 Nov 29;7:13653. doi: 10.1038/ncomms13653.


Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.

Juras A, Chyleński M, Krenz-Niedbała M, Malmström H, Ehler E, Pospieszny Ł, Łukasik S, Bednarczyk J, Piontek J, Jakobsson M, Dabert M.

Forensic Sci Int Genet. 2017 Jan;26:30-39. doi: 10.1016/j.fsigen.2016.10.008. Epub 2016 Oct 14.


Genes mirror migrations and cultures in prehistoric Europe-a population genomic perspective.

Günther T, Jakobsson M.

Curr Opin Genet Dev. 2016 Dec;41:115-123. doi: 10.1016/j.gde.2016.09.004. Epub 2016 Sep 27. Review.


The disappearing San of southeastern Africa and their genetic affinities.

Schlebusch CM, Prins F, Lombard M, Jakobsson M, Soodyall H.

Hum Genet. 2016 Dec;135(12):1365-1373. Epub 2016 Sep 20.


Inferring Past Effective Population Size from Distributions of Coalescent Times.

Gattepaille L, Günther T, Jakobsson M.

Genetics. 2016 Nov;204(3):1191-1206. doi: 10.1534/genetics.115.185058. Epub 2016 Sep 16.


Palliative care consultation team on acute wards-an intervention study with pre-post comparisons.

Friedrichsen M, Hajradinovic Y, Jakobsson M, Milberg P, Milberg A.

Support Care Cancer. 2017 Feb;25(2):371-380. doi: 10.1007/s00520-016-3406-9. Epub 2016 Sep 16.


Use of the PREPARE (PREhabilitation, Physical Activity and exeRcisE) program to improve outcomes after lumbar fusion surgery for severe low back pain: a study protocol of a person-centred randomised controlled trial.

Lotzke H, Jakobsson M, Brisby H, Gutke A, Hägg O, Smeets R, den Hollander M, Olsson LE, Lundberg M.

BMC Musculoskelet Disord. 2016 Aug 18;17(1):349. doi: 10.1186/s12891-016-1203-8.


The Demographic Development of the First Farmers in Anatolia.

Kılınç GM, Omrak A, Özer F, Günther T, Büyükkarakaya AM, Bıçakçı E, Baird D, Dönertaş HM, Ghalichi A, Yaka R, Koptekin D, Açan SC, Parvizi P, Krzewińska M, Daskalaki EA, Yüncü E, Dağtaş ND, Fairbairn A, Pearson J, Mustafaoğlu G, Erdal YS, Çakan YG, Togan İ, Somel M, Storå J, Jakobsson M, Götherström A.

Curr Biol. 2016 Oct 10;26(19):2659-2666. doi: 10.1016/j.cub.2016.07.057. Epub 2016 Aug 4.


Randomised trial on treatment of vaginal intraepithelial neoplasia-Imiquimod, laser vaporisation and expectant management.

Tainio K, Jakobsson M, Louvanto K, Kalliala I, Paavonen J, Nieminen P, Riska A.

Int J Cancer. 2016 Nov 15;139(10):2353-8. doi: 10.1002/ijc.30275. Epub 2016 Jul 28.


Protein lysine methylation by seven-β-strand methyltransferases.

Falnes PØ, Jakobsson ME, Davydova E, Ho A, Małecki J.

Biochem J. 2016 Jul 15;473(14):1995-2009. doi: 10.1042/BCJ20160117. Review.


Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc.

Jeong C, Ozga AT, Witonsky DB, Malmström H, Edlund H, Hofman CA, Hagan RW, Jakobsson M, Lewis CM, Aldenderfer MS, Di Rienzo A, Warinner C.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7485-90. doi: 10.1073/pnas.1520844113. Epub 2016 Jun 20.


Correspondence: On the enzymology and significance of HSPA1 lysine methylation.

Jakobsson ME, Moen A, Falnes PØ.

Nat Commun. 2016 Jun 20;7:11464. doi: 10.1038/ncomms11464. No abstract available.


The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa.

Hervella M, Svensson EM, Alberdi A, Günther T, Izagirre N, Munters AR, Alonso S, Ioana M, Ridiche F, Soficaru A, Jakobsson M, Netea MG, de-la-Rua C.

Sci Rep. 2016 May 19;6:25501. doi: 10.1038/srep25501.


Evidence for an ice shelf covering the central Arctic Ocean during the penultimate glaciation.

Jakobsson M, Nilsson J, Anderson L, Backman J, Björk G, Cronin TM, Kirchner N, Koshurnikov A, Mayer L, Noormets R, O'Regan M, Stranne C, Ananiev R, Barrientos Macho N, Cherniykh D, Coxall H, Eriksson B, Flodén T, Gemery L, Gustafsson Ö, Jerram K, Johansson C, Khortov A, Mohammad R, Semiletov I.

Nat Commun. 2016 Jan 18;7:10365. doi: 10.1038/ncomms10365.


Genomic Evidence Establishes Anatolia as the Source of the European Neolithic Gene Pool.

Omrak A, Günther T, Valdiosera C, Svensson EM, Malmström H, Kiesewetter H, Aylward W, Storå J, Jakobsson M, Götherström A.

Curr Biol. 2016 Jan 25;26(2):270-275. doi: 10.1016/j.cub.2015.12.019. Epub 2015 Dec 31.


Arsenic stress after the Proterozoic glaciations.

Fru EC, Arvestål E, Callac N, El Albani A, Kilias S, Argyraki A, Jakobsson M.

Sci Rep. 2015 Dec 4;5:17789. doi: 10.1038/srep17789.


Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.

Jakobsson ME, Moen A, Davidson B, Falnes PØ.

PLoS One. 2015 Oct 8;10(10):e0140168. doi: 10.1371/journal.pone.0140168. eCollection 2015.


Neonatal outcomes after the obstetric near-miss events uterine rupture, abnormally invasive placenta and emergency peripartum hysterectomy - prospective data from the 2009-2011 Finnish NOSS study.

Jakobsson M, Tapper AM, Palomäki O, Ojala K, Pallasmaa N, Ordén MR, Gissler M.

Acta Obstet Gynecol Scand. 2015 Dec;94(12):1387-94. doi: 10.1111/aogs.12780. Epub 2015 Oct 15.


Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques.

Günther T, Valdiosera C, Malmström H, Ureña I, Rodriguez-Varela R, Sverrisdóttir ÓO, Daskalaki EA, Skoglund P, Naidoo T, Svensson EM, Bermúdez de Castro JM, Carbonell E, Dunn M, Storå J, Iriarte E, Arsuaga JL, Carretero JM, Götherström A, Jakobsson M.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11917-22. doi: 10.1073/pnas.1509851112. Epub 2015 Sep 8.


HaploPOP: a software that improves population assignment by combining markers into haplotypes.

Duforet-Frebourg N, Gattepaille LM, Blum MG, Jakobsson M.

BMC Bioinformatics. 2015 Jul 31;16:242. doi: 10.1186/s12859-015-0661-6.

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