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Items: 29

1.

An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.

Wang T, Lu R, Kapur P, Jaiswal BS, Hannan R, Zhang Z, Pedrosa I, Luke JJ, Zhang H, Goldstein LD, Yousuf Q, Gu YF, McKenzie T, Joyce A, Kim MS, Wang X, Luo D, Onabolu O, Stevens C, Xie Z, Chen M, Filatenkov A, Torrealba J, Luo X, Guo W, He J, Stawiski E, Modrusan Z, Durinck S, Seshagiri S, Brugarolas J.

Cancer Discov. 2018 Jun 8. pii: CD-17-1246. doi: 10.1158/2159-8290.CD-17-1246. [Epub ahead of print]

PMID:
29884728
2.

ERK mutations and amplification confer resistance to ERK-inhibitor therapy.

Jaiswal BS, Durinck S, Stawiski E, Yin J, Wang W, Lin E, Moffat JG, Martin S, Modrusan Z, Seshagiri S.

Clin Cancer Res. 2018 May 14. pii: clincanres.3674.2017. doi: 10.1158/1078-0432.CCR-17-3674. [Epub ahead of print]

PMID:
29760222
3.

Next-Generation Sequencing Reveals Novel Mutations in X-linked Intellectual Disability.

Muthusamy B, Selvan LDN, Nguyen TT, Manoj J, Stawiski EW, Jaiswal BS, Wang W, Raja R, Ramprasad VL, Gupta R, Murugan S, Kadandale JS, Prasad TSK, Reddy K, Peterson A, Pandey A, Seshagiri S, Girimaji SC, Gowda H.

OMICS. 2017 May;21(5):295-303. doi: 10.1089/omi.2017.0009.

4.

Antioxidant and anti-inflammatory activities of Aerva pseudotomentosa leaves.

Pandey A, Kaushik A, Wanjari M, Dey YN, Jaiswal BS, Dhodi A.

Pharm Biol. 2017 Dec;55(1):1688-1697. doi: 10.1080/13880209.2017.1321022. Erratum in: Pharm Biol. 2017 Dec;55(1):2298.

PMID:
28454506
5.

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.

Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S.

Nat Genet. 2016 Apr;48(4):407-16. doi: 10.1038/ng.3520. Epub 2016 Feb 29.

PMID:
26928227
6.

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.

Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S.

Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17.

7.

Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration.

Mooz J, Oberoi-Khanuja TK, Harms GS, Wang W, Jaiswal BS, Seshagiri S, Tikkanen R, Rajalingam K.

Sci Signal. 2014 Aug 5;7(337):ra73. doi: 10.1126/scisignal.2005484.

PMID:
25097033
8.

An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins.

Hazen M, Bhakta S, Vij R, Randle S, Kallop D, Chiang V, Hötzel I, Jaiswal BS, Ervin KE, Li B, Weimer RM, Polakis P, Scheller RH, Junutula JR, Hongo JA.

MAbs. 2014 Jan-Feb;6(1):95-107.

9.

Oncogenic ERBB3 mutations in human cancers.

Jaiswal BS, Kljavin NM, Stawiski EW, Chan E, Parikh C, Durinck S, Chaudhuri S, Pujara K, Guillory J, Edgar KA, Janakiraman V, Scholz RP, Bowman KK, Lorenzo M, Li H, Wu J, Yuan W, Peters BA, Kan Z, Stinson J, Mak M, Modrusan Z, Eigenbrot C, Firestein R, Stern HM, Rajalingam K, Schaefer G, Merchant MA, Sliwkowski MX, de Sauvage FJ, Seshagiri S.

Cancer Cell. 2013 May 13;23(5):603-17. doi: 10.1016/j.ccr.2013.04.012. Erratum in: Cancer Cell. 2014 Apr 14;25(4):543-4.

10.

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.

Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, Gentleman R, Chaudhuri S, Janakiraman V, Jaiswal BS, Parikh C, Yuan W, Zhang Z, Koeppen H, Wu TD, Stern HM, Yauch RL, Huffman KE, Paskulin DD, Illei PB, Varella-Garcia M, Gazdar AF, de Sauvage FJ, Bourgon R, Minna JD, Brock MV, Seshagiri S.

Nat Genet. 2012 Oct;44(10):1111-6. doi: 10.1038/ng.2405. Epub 2012 Sep 2.

11.

Recurrent R-spondin fusions in colon cancer.

Seshagiri S, Stawiski EW, Durinck S, Modrusan Z, Storm EE, Conboy CB, Chaudhuri S, Guan Y, Janakiraman V, Jaiswal BS, Guillory J, Ha C, Dijkgraaf GJ, Stinson J, Gnad F, Huntley MA, Degenhardt JD, Haverty PM, Bourgon R, Wang W, Koeppen H, Gentleman R, Starr TK, Zhang Z, Largaespada DA, Wu TD, de Sauvage FJ.

Nature. 2012 Aug 30;488(7413):660-4. doi: 10.1038/nature11282.

12.

In vitro initiated sperm forward motility in caput spermatozoa: weak and transient.

Das K, Das S, Bhoumik A, Jaiswal BS, Majumder GC, Dungdung SR.

Andrologia. 2012 May;44 Suppl 1:807-12. doi: 10.1111/j.1439-0272.2011.01161.x. Epub 2011 May 19.

PMID:
21592177
13.

Diverse somatic mutation patterns and pathway alterations in human cancers.

Kan Z, Jaiswal BS, Stinson J, Janakiraman V, Bhatt D, Stern HM, Yue P, Haverty PM, Bourgon R, Zheng J, Moorhead M, Chaudhuri S, Tomsho LP, Peters BA, Pujara K, Cordes S, Davis DP, Carlton VE, Yuan W, Li L, Wang W, Eigenbrot C, Kaminker JS, Eberhard DA, Waring P, Schuster SC, Modrusan Z, Zhang Z, Stokoe D, de Sauvage FJ, Faham M, Seshagiri S.

Nature. 2010 Aug 12;466(7308):869-73. doi: 10.1038/nature09208. Epub 2010 Jul 28.

PMID:
20668451
14.

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.

Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S.

Nature. 2010 Mar 18;464(7287):431-5. doi: 10.1038/nature08833. Epub 2010 Feb 3.

PMID:
20130576
15.

Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation.

Jaiswal BS, Janakiraman V, Kljavin NM, Chaudhuri S, Stern HM, Wang W, Kan Z, Dbouk HA, Peters BA, Waring P, Dela Vega T, Kenski DM, Bowman KK, Lorenzo M, Li H, Wu J, Modrusan Z, Stinson J, Eby M, Yue P, Kaminker JS, de Sauvage FJ, Backer JM, Seshagiri S.

Cancer Cell. 2009 Dec 8;16(6):463-74. doi: 10.1016/j.ccr.2009.10.016.

16.

Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants.

Wu H, Shekar SC, Flinn RJ, El-Sibai M, Jaiswal BS, Sen KI, Janakiraman V, Seshagiri S, Gerfen GJ, Girvin ME, Backer JM.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20258-63. doi: 10.1073/pnas.0902369106. Epub 2009 Nov 13.

17.

Purification and characterization of a motility initiating protein from caprine epididymal plasma.

Jaiswal BS, Das K, Saha S, Dungdung SR, Majumder GC.

J Cell Physiol. 2010 Jan;222(1):254-63. doi: 10.1002/jcp.21947.

PMID:
19795390
18.

Effect of Solanum torvum on blood pressure and metabolic alterations in fructose hypertensive rats.

Mohan M, Jaiswal BS, Kasture S.

J Ethnopharmacol. 2009 Oct 29;126(1):86-9. doi: 10.1016/j.jep.2009.08.008. Epub 2009 Aug 13.

PMID:
19683046
19.

Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.

Jaiswal BS, Janakiraman V, Kljavin NM, Eastham-Anderson J, Cupp JE, Liang Y, Davis DP, Hoeflich KP, Seshagiri S.

PLoS One. 2009 May 27;4(5):e5717. doi: 10.1371/journal.pone.0005717.

20.

Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.

Xie F, Garcia MA, Carlson AE, Schuh SM, Babcock DF, Jaiswal BS, Gossen JA, Esposito G, van Duin M, Conti M.

Dev Biol. 2006 Aug 15;296(2):353-62. Epub 2006 Jun 7.

21.

Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.

Esposito G, Jaiswal BS, Xie F, Krajnc-Franken MA, Robben TJ, Strik AM, Kuil C, Philipsen RL, van Duin M, Conti M, Gossen JA.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2993-8. Epub 2004 Feb 19. Erratum in: Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5180. Jaiswal Byjay S [corrected to Jaiswal Bijay S].

22.

Calcium regulation of the soluble adenylyl cyclase expressed in mammalian spermatozoa.

Jaiswal BS, Conti M.

Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10676-81. Epub 2003 Sep 4.

23.

Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase.

Jaiswal BS, Conti M.

J Biol Chem. 2001 Aug 24;276(34):31698-708. Epub 2001 Jun 21.

24.
25.

Detection of partial and complete acrosome reaction in human spermatozoa: which inducers and probes to use?

Jaiswal BS, Eisenbach M, Tur-Kaspa I.

Mol Hum Reprod. 1999 Mar;5(3):214-9.

PMID:
10333354
26.

Human sperm chemotaxis: is progesterone a chemoattractant?

Jaiswal BS, Tur-Kaspa I, Dor J, Mashiach S, Eisenbach M.

Biol Reprod. 1999 Jun;60(6):1314-9.

PMID:
10330086
27.

Sperm capacitation is, after all, a prerequisite for both partial and complete acrosome reaction.

Jaiswal BS, Cohen-Dayag A, Tur-Kaspa I, Eisenbach M.

FEBS Lett. 1998 May 8;427(2):309-13.

28.

In-vitro initiation of forward motility in testicular spermatozoa.

Jaiswal BS, Majumder GC.

Int J Androl. 1996 Apr;19(2):97-102.

PMID:
8737040
29.

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