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Items: 23

1.

Urinary miRNAs as Biomarkers for Noninvasive Evaluation of Radiation-Induced Renal Tubular Injury.

Bhayana S, Song F, Jacob J, Fadda P, Denko NC, Xu-Welliver M, Chakravarti A, Jacob NK.

Radiat Res. 2017 Dec;188(6):626-635. doi: 10.1667/RR14828.1. Epub 2017 Oct 4.

PMID:
28977780
2.

A novel interaction of PAK4 with PPARĪ³ to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma.

Kesanakurti D, Maddirela D, Banasavadi-Siddegowda YK, Lai TH, Qamri Z, Jacob NK, Sampath D, Mohanam S, Kaur B, Puduvalli VK.

Oncogene. 2017 Sep 14;36(37):5309-5320. doi: 10.1038/onc.2016.261. Epub 2017 May 22.

3.

Detection of Acute Radiation Sickness: A Feasibility Study in Non-Human Primates Circulating miRNAs for Triage in Radiological Events.

Menon N, Rogers CJ, Lukaszewicz AI, Axtelle J, Yadav M, Song F, Chakravarti A, Jacob NK.

PLoS One. 2016 Dec 1;11(12):e0167333. doi: 10.1371/journal.pone.0167333. eCollection 2016.

4.

MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches.

Markowitz J, Abrams Z, Jacob NK, Zhang X, Hassani JN, Latchana N, Wei L, Regan KE, Brooks TR, Uppati SR, Levine KM, Bekaii-Saab T, Kendra KL, Lesinski GB, Howard JH, Olencki T, Payne PR, Carson WE 3rd.

Onco Targets Ther. 2016 Sep 29;9:5931-5941. eCollection 2016.

5.

Alterative Expression and Localization of Profilin 1/VASPpS157 and Cofilin 1/VASPpS239 Regulates Metastatic Growth and Is Modified by DHA Supplementation.

Ali M, Heyob K, Jacob NK, Rogers LK.

Mol Cancer Ther. 2016 Sep;15(9):2220-31. doi: 10.1158/1535-7163.MCT-16-0092. Epub 2016 Aug 5.

6.

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma.

Wojton J, Meisen WH, Jacob NK, Thorne AH, Hardcastle J, Denton N, Chu Z, Dmitrieva N, Marsh R, Van Meir EG, Kwon CH, Chakravarti A, Qi X, Kaur B.

Oncotarget. 2014 Oct 30;5(20):9703-9.

7.

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.

Gasparini P, Lovat F, Fassan M, Casadei L, Cascione L, Jacob NK, Carasi S, Palmieri D, Costinean S, Shapiro CL, Huebner K, Croce CM.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4536-41. doi: 10.1073/pnas.1402604111. Epub 2014 Mar 10. Erratum in: Proc Natl Acad Sci U S A. 2017 Mar 7;114(10 ):E2065.

8.

Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.

Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton JT, Smith PL, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon CH, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA.

Cancer Res. 2014 Mar 15;74(6):1752-65. doi: 10.1158/0008-5472.CAN-13-0884. Epub 2014 Jan 22.

9.

Isolation and analysis of linker histones across cellular compartments.

Harshman SW, Chen MM, Branson OE, Jacob NK, Johnson AJ, Byrd JC, Freitas MA.

J Proteomics. 2013 Oct 8;91:595-604. doi: 10.1016/j.jprot.2013.08.022. Epub 2013 Sep 5.

10.

Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle.

Chettiar SN, Cooley JV, Park IH, Bhasin D, Chakravarti A, Li PK, Li C, Jacob NK.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5429-33. doi: 10.1016/j.bmcl.2013.07.034. Epub 2013 Jul 24.

PMID:
23968825
11.

Glycovariant anti-CD37 monospecific protein therapeutic exhibits enhanced effector cell-mediated cytotoxicity against chronic and acute B cell malignancies.

Rafiq S, Siadak A, Butchar JP, Cheney C, Lozanski G, Jacob NK, Lapalombella R, McGourty J, Moledor M, Lowe R, Setter B, Jones J, Flynn JM, Andritsos L, Devine S, Mo X, Jarjoura D, Tridandapani S, Algate P, Byrd JC, Muthusamy N.

MAbs. 2013 Sep-Oct;5(5):723-35. doi: 10.4161/mabs.25282. Epub 2013 Jun 7.

12.

Self care integrative treatment demonstrated in rural community setting improves health related quality of life of lymphatic filariasis patients in endemic villages.

Aggithaya MG, Narahari SR, Vayalil S, Shefuvan M, Jacob NK, Sushma KV.

Acta Trop. 2013 Jun;126(3):198-204. doi: 10.1016/j.actatropica.2013.02.022. Epub 2013 Mar 13.

PMID:
23499714
13.

Identification of sensitive serum microRNA biomarkers for radiation biodosimetry.

Jacob NK, Cooley JV, Yee TN, Jacob J, Alder H, Wickramasinghe P, Maclean KH, Chakravarti A.

PLoS One. 2013;8(2):e57603. doi: 10.1371/journal.pone.0057603. Epub 2013 Feb 25.

14.

Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation.

Jacob NK, Cooley JV, Shirai K, Chakravarti A.

Onco Targets Ther. 2012;5:7-20. doi: 10.2147/OTT.S28147. Epub 2012 Feb 15.

15.

RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair.

Wang J, Jacob NK, Ladner KJ, Beg A, Perko JD, Tanner SM, Liyanarachchi S, Fishel R, Guttridge DC.

EMBO Rep. 2009 Nov;10(11):1272-8. doi: 10.1038/embor.2009.197. Epub 2009 Sep 25.

16.

Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography-mass spectrometry.

Su X, Jacob NK, Amunugama R, Hsu PH, Fishel R, Freitas MA.

Anal Biochem. 2009 May 1;388(1):47-55. doi: 10.1016/j.ab.2009.01.033. Epub 2009 Feb 3.

17.

Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1.

Nadella KS, Saji M, Jacob NK, Pavel E, Ringel MD, Kirschner LS.

EMBO Rep. 2009 Jun;10(6):599-605. doi: 10.1038/embor.2009.58. Epub 2009 May 8. Erratum in: EMBO Rep. 2009 Sep;10(9):1066.

18.

Liquid chromatography mass spectrometry profiling of histones.

Su X, Jacob NK, Amunugama R, Lucas DM, Knapp AR, Ren C, Davis ME, Marcucci G, Parthun MR, Byrd JC, Fishel R, Freitas MA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):440-54. Epub 2007 Jan 7.

19.

Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint.

Jacob NK, Lescasse R, Linger BR, Price CM.

Mol Cell Biol. 2007 Mar;27(5):1592-601. Epub 2006 Dec 11.

20.

Engineering the end: DNA processing at human telomeres.

Price C, Jacob NK.

Mol Cell. 2005 Apr 15;18(2):147-8.

21.

Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres.

Jacob NK, Stout AR, Price CM.

Mol Biol Cell. 2004 Aug;15(8):3719-28. Epub 2004 May 28.

22.

Generation of telomeric G strand overhangs involves both G and C strand cleavage.

Jacob NK, Kirk KE, Price CM.

Mol Cell. 2003 Apr;11(4):1021-32.

23.

G-overhang dynamics at Tetrahymena telomeres.

Jacob NK, Skopp R, Price CM.

EMBO J. 2001 Aug 1;20(15):4299-308.

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