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Items: 1 to 50 of 410

1.

The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma.

Ziebart A, Huber U, Jeske S, Laban S, Doescher J, Hoffmann TK, Brunner C, Jackson EK, Schuler PJ.

Oncotarget. 2017 Dec 20;9(5):5834-5847. doi: 10.18632/oncotarget.23533. eCollection 2018 Jan 19.

PMID:
29464038
2.

BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro.

Jackson TC, Kotermanski SE, Jackson EK, Kochanek PM.

Exp Neurol. 2018 Feb;300:232-246. doi: 10.1016/j.expneurol.2017.11.013. Epub 2017 Dec 1.

3.

SDF-1α (Stromal Cell-Derived Factor 1α) Induces Cardiac Fibroblasts, Renal Microvascular Smooth Muscle Cells, and Glomerular Mesangial Cells to Proliferate, Cause Hypertrophy, and Produce Collagen.

Jackson EK, Zhang Y, Gillespie DD, Zhu X, Cheng D, Jackson TC.

J Am Heart Assoc. 2017 Nov 7;6(11). pii: e007253. doi: 10.1161/JAHA.117.007253.

4.

Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia.

Hong CS, Sharma P, Yerneni SS, Simms P, Jackson EK, Whiteside TL, Boyiadzis M.

Sci Rep. 2017 Oct 31;7(1):14684. doi: 10.1038/s41598-017-14661-w.

5.

8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects.

Jackson EK, Mi Z.

J Pharmacol Exp Ther. 2017 Dec;363(3):358-366. doi: 10.1124/jpet.117.243758. Epub 2017 Sep 19.

PMID:
28928119
6.

Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms.

Muller L, Simms P, Hong CS, Nishimura MI, Jackson EK, Watkins SC, Whiteside TL.

Oncoimmunology. 2017 Jul 19;6(8):e1261243. doi: 10.1080/2162402X.2016.1261243. eCollection 2017.

PMID:
28919985
7.

Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway.

Keller AS, Diederich L, Panknin C, DeLalio LJ, Drake JC, Sherman R, Jackson EK, Yan Z, Kelm M, Cortese-Krott MM, Isakson BE.

Am J Physiol Cell Physiol. 2017 Dec 1;313(6):C593-C603. doi: 10.1152/ajpcell.00178.2017. Epub 2017 Aug 30.

PMID:
28855161
8.

Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway.

Long KR, Shipman KE, Rbaibi Y, Menshikova EV, Ritov VB, Eshbach ML, Jiang Y, Jackson EK, Baty CJ, Weisz OA.

Mol Biol Cell. 2017 Sep 15;28(19):2508-2517. doi: 10.1091/mbc.E17-04-0211. Epub 2017 Jul 18.

9.

Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck Cancer.

Ludwig S, Floros T, Theodoraki MN, Hong CS, Jackson EK, Lang S, Whiteside TL.

Clin Cancer Res. 2017 Aug 15;23(16):4843-4854. doi: 10.1158/1078-0432.CCR-16-2819. Epub 2017 Apr 11.

PMID:
28400428
10.

Adenosine production by brain cells.

Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM.

J Neurochem. 2017 Jun;141(5):676-693. doi: 10.1111/jnc.14018. Epub 2017 Apr 6.

PMID:
28294336
11.

Editorial for "Hypertension's 3 Dilemmas & 3 Solutions: Pharmacology of the Kidney in Hypertension".

Jackson EK.

J Cardiovasc Pharmacol. 2017 Mar;69(3):127-128. doi: 10.1097/FJC.0000000000000457. No abstract available.

PMID:
28267686
12.

Alkaline Phosphatase Inhibitors Attenuate Renovascular Responses to Norepinephrine.

Jackson EK, Zhang Y, Cheng D.

Hypertension. 2017 Mar;69(3):484-493. doi: 10.1161/HYPERTENSIONAHA.116.08623. Epub 2017 Jan 30.

PMID:
28137984
13.

RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells.

Zhu X, Jackson EK.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F565-F576. doi: 10.1152/ajprenal.00547.2016. Epub 2017 Jan 18.

PMID:
28100502
14.

Context-dependent effects of dipeptidyl peptidase 4 inhibitors.

Jackson EK.

Curr Opin Nephrol Hypertens. 2017 Mar;26(2):83-90. doi: 10.1097/MNH.0000000000000303.

PMID:
27898522
15.

A pilot study of health and wellness coaching for fibromyalgia.

Hackshaw KV, Plans-Pujolras M, Rodriguez-Saona LE, Moore MA, Jackson EK, Sforzo GA, Buffington CA.

BMC Musculoskelet Disord. 2016 Nov 8;17(1):457.

16.

The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney.

Ramani K, Garg AV, Jawale CV, Conti HR, Whibley N, Jackson EK, Shiva SS, Horne W, Kolls JK, Gaffen SL, Biswas PS.

PLoS Pathog. 2016 Nov 4;12(11):e1005952. doi: 10.1371/journal.ppat.1005952. eCollection 2016 Nov.

17.

8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity.

Jackson EK, Gillespie DG, Mi Z.

J Pharmacol Exp Ther. 2016 Dec;359(3):420-435. Epub 2016 Sep 27. Erratum in: J Pharmacol Exp Ther. 2017 Dec;363(3):411.

18.

Estrogens in Men: Another Layer of Complexity of Estradiol Metabolism in Pulmonary Hypertension.

Tofovic SP, Jackson EK.

Am J Respir Crit Care Med. 2016 May 15;193(10):1087-90. doi: 10.1164/rccm.201512-2541ED. No abstract available.

19.

Phenotypic and functional characteristics of CD39high human regulatory B cells (Breg).

Figueiró F, Muller L, Funk S, Jackson EK, Battastini AM, Whiteside TL.

Oncoimmunology. 2016 Feb 26;5(2):e1082703. eCollection 2016 Feb.

20.

Adenosine metabolism of human mesenchymal stromal cells isolated from patients with head and neck squamous cell carcinoma.

Schuler PJ, Westerkamp AM, Kansy BA, Bruderek K, Dissmann PA, Dumitru CA, Lang S, Jackson EK, Brandau S.

Immunobiology. 2017 Jan;222(1):66-74. doi: 10.1016/j.imbio.2016.01.013. Epub 2016 Jan 30.

PMID:
26898925
21.

Purines: forgotten mediators in traumatic brain injury.

Jackson EK, Boison D, Schwarzschild MA, Kochanek PM.

J Neurochem. 2016 Apr;137(2):142-53. doi: 10.1111/jnc.13551. Epub 2016 Feb 25. Review.

22.

2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism.

Schaufelberger SA, Rosselli M, Barchiesi F, Gillespie DG, Jackson EK, Dubey RK.

Am J Physiol Endocrinol Metab. 2016 Mar 1;310(5):E313-22. doi: 10.1152/ajpendo.00418.2015. Epub 2016 Jan 5.

23.

Discovery and Roles of 2',3'-cAMP in Biological Systems.

Jackson EK.

Handb Exp Pharmacol. 2017;238:229-252. doi: 10.1007/164_2015_40. Review.

PMID:
26721674
24.

Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction.

Tofovic SP, Salah EM, Smits GJ, Whalley ET, Ticho B, Deykin A, Jackson EK.

J Pharmacol Exp Ther. 2016 Feb;356(2):333-40. doi: 10.1124/jpet.115.228841. Epub 2015 Nov 19.

25.

Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion.

Jackson EK, Menshikova EV, Mi Z, Verrier JD, Bansal R, Janesko-Feldman K, Jackson TC, Kochanek PM.

J Am Soc Nephrol. 2016 Jul;27(7):2069-81. doi: 10.1681/ASN.2015040397. Epub 2015 Nov 16.

26.

2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.

Rigassi L, Barchiesi Bozzolo F, Lucchinetti E, Zaugg M, Fingerle J, Rosselli M, Imthurn B, Jackson EK, Dubey RK.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E995-1007. doi: 10.1152/ajpendo.00267.2015. Epub 2015 Oct 20.

27.

Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.

Dubey RK, Fingerle J, Gillespie DG, Mi Z, Rosselli M, Imthurn B, Jackson EK.

Hypertension. 2015 Dec;66(6):1207-19. doi: 10.1161/HYPERTENSIONAHA.115.05912. Epub 2015 Sep 28.

28.

NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4.

Zhu X, Gillespie DG, Jackson EK.

Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1528-42. doi: 10.1152/ajpheart.00070.2015. Epub 2015 Sep 14.

29.

Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons.

Jackson TC, Manole MD, Kotermanski SE, Jackson EK, Clark RS, Kochanek PM.

Neuroscience. 2015 Oct 1;305:268-78. doi: 10.1016/j.neuroscience.2015.08.012. Epub 2015 Aug 8.

30.

Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.

He T, Brocca-Cofano E, Gillespie DG, Xu C, Stock JL, Ma D, Policicchio BB, Raehtz KD, Rinaldo CR, Apetrei C, Jackson EK, Macatangay BJ, Pandrea I.

J Virol. 2015 Sep;89(18):9616-30. doi: 10.1128/JVI.01196-15. Epub 2015 Jul 15.

31.

Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.

Diamond ML, Ritter AC, Jackson EK, Conley YP, Kochanek PM, Boison D, Wagner AK.

Epilepsia. 2015 Aug;56(8):1198-206. doi: 10.1111/epi.13044. Epub 2015 Jun 4.

32.

Chromothripsis from DNA damage in micronuclei.

Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D.

Nature. 2015 Jun 11;522(7555):179-84. doi: 10.1038/nature14493. Epub 2015 May 27.

33.

Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.

Rahaman MM, Reinders FG, Koes D, Nguyen AT, Mutchler SM, Sparacino-Watkins C, Alvarez RA, Miller MP, Cheng D, Chen BB, Jackson EK, Camacho CJ, Straub AC.

J Biol Chem. 2015 Jul 3;290(27):16861-72. doi: 10.1074/jbc.M114.629964. Epub 2015 May 22.

34.

Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP.

Verrier JD, Kochanek PM, Jackson EK.

J Pharmacol Exp Ther. 2015 Aug;354(2):175-83. doi: 10.1124/jpet.115.225219. Epub 2015 May 21.

35.

Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies.

Jackson TC, Bayir H, Ikonomovic MD, Janesko-Feldman K, Mi Z, Gao T, Jackson EK, Kochanek PM.

Sci Rep. 2015 Apr 1;5:9377. doi: 10.1038/srep09377.

36.

Immunological mechanisms of the antitumor effects of supplemental oxygenation.

Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, Podack ER, Ohta A, Sitkovsky MV.

Sci Transl Med. 2015 Mar 4;7(277):277ra30. doi: 10.1126/scitranslmed.aaa1260.

37.

Emerging therapies in traumatic brain injury.

Kochanek PM, Jackson TC, Ferguson NM, Carlson SW, Simon DW, Brockman EC, Ji J, Bayır H, Poloyac SM, Wagner AK, Kline AE, Empey PE, Clark RS, Jackson EK, Dixon CE.

Semin Neurol. 2015 Feb;35(1):83-100. doi: 10.1055/s-0035-1544237. Epub 2015 Feb 25. Review.

38.

The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.

Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM.

J Cereb Blood Flow Metab. 2015 Mar 31;35(4):655-66. doi: 10.1038/jcbfm.2014.242.

39.

Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema.

Miller RL, Denny GO, Knuepfer MM, Kleyman TR, Jackson EK, Salkoff LB, Loewy AD.

Brain Res. 2015 Mar 19;1601:40-51. doi: 10.1016/j.brainres.2014.12.048. Epub 2014 Dec 31.

40.

2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors.

Newell EA, Exo JL, Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Kochanek PM, Jackson EK.

Brain Res. 2015 Jan 12;1594:27-35. doi: 10.1016/j.brainres.2014.10.059. Epub 2014 Nov 3.

41.

Effect of dipeptidyl peptidase 4 inhibition on arterial blood pressure is context dependent.

Jackson EK, Mi Z, Tofovic SP, Gillespie DG.

Hypertension. 2015 Jan;65(1):238-49. doi: 10.1161/HYPERTENSIONAHA.114.04631. Epub 2014 Nov 3. Erratum in: Hypertension. 2015 Apr;65(4):e17.

42.

Prevention of skin carcinogenesis by the β-blocker carvedilol.

Chang A, Yeung S, Thakkar A, Huang KM, Liu MM, Kanassatega RS, Parsa C, Orlando R, Jackson EK, Andresen BT, Huang Y.

Cancer Prev Res (Phila). 2015 Jan;8(1):27-36. doi: 10.1158/1940-6207.CAPR-14-0193. Epub 2014 Nov 3.

43.

Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.

Hatfield SM, Kjaergaard J, Lukashev D, Belikoff B, Schreiber TH, Sethumadhavan S, Abbott R, Philbrook P, Thayer M, Shujia D, Rodig S, Kutok JL, Ren J, Ohta A, Podack ER, Karger B, Jackson EK, Sitkovsky M.

J Mol Med (Berl). 2014 Dec;92(12):1283-92. doi: 10.1007/s00109-014-1189-3. Epub 2014 Aug 15.

44.

Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation.

Wei Y, Liao Y, Zavilowitz B, Ren J, Liu W, Chan P, Rohatgi R, Estilo G, Jackson EK, Wang WH, Satlin LM.

Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F833-43. doi: 10.1152/ajprenal.00141.2014. Epub 2014 Aug 6.

45.

The guanosine-adenosine interaction exists in vivo.

Jackson EK, Mi Z.

J Pharmacol Exp Ther. 2014 Sep;350(3):719-26. doi: 10.1124/jpet.114.216978. Epub 2014 Jul 7.

46.

Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP.

Jackson EK, Cheng D, Verrier JD, Janesko-Feldman K, Kochanek PM.

Am J Physiol Renal Physiol. 2014 Sep 15;307(6):F680-5. doi: 10.1152/ajprenal.00312.2014. Epub 2014 Jul 2.

47.

Guanosine regulates adenosine levels in the kidney.

Jackson EK, Cheng D, Mi Z, Gillespie DG.

Physiol Rep. 2014 May 28;2(5). pii: e12028. doi: 10.14814/phy2.12028. Print 2014 May 1.

48.

Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway.

Jackson EK, Gillespie DG, Mi Z, Cheng D, Bansal R, Janesko-Feldman K, Kochanek PM.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F14-24. doi: 10.1152/ajprenal.00134.2014. Epub 2014 May 7.

49.

Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice.

Shein SL, Shellington DK, Exo JL, Jackson TC, Wisniewski SR, Jackson EK, Vagni VA, Bayır H, Clark RS, Dixon CE, Janesko-Feldman KL, Kochanek PM.

J Neurotrauma. 2014 Aug 15;31(16):1386-95. doi: 10.1089/neu.2013.2985.

50.

Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.

Schuler PJ, Saze Z, Hong CS, Muller L, Gillespie DG, Cheng D, Harasymczuk M, Mandapathil M, Lang S, Jackson EK, Whiteside TL.

Clin Exp Immunol. 2014 Aug;177(2):531-43. doi: 10.1111/cei.12354.

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