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Items: 46


Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells.

Cho S, Abbas A, Irianto J, Ivanovska IL, Xia Y, Tewari M, Discher DE.

Nucleus. 2018 Jan 1;9(1):230-245. doi: 10.1080/19491034.2018.1460185.


Filomicelles Deliver a Chemo-Differentiation Combination of Paclitaxel and Retinoic Acid That Durably Represses Carcinomas in Liver to Prolong Survival.

Nair PR, Alvey C, Jin X, Irianto J, Ivanovska I, Discher DE.

Bioconjug Chem. 2018 Apr 18;29(4):914-927. doi: 10.1021/acs.bioconjchem.7b00816. Epub 2018 Mar 1.


Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation.

Ivanovska IL, Swift J, Spinler K, Dingal D, Cho S, Discher DE.

Mol Biol Cell. 2017 Jul 7;28(14):2010-2022. doi: 10.1091/mbc.E17-01-0010. Epub 2017 May 31.


Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor.

Elwood F, Witter DJ, Piesvaux J, Kraybill B, Bays N, Alpert C, Goldenblatt P, Qu Y, Ivanovska I, Lee HH, Chiu CS, Tang H, Scott ME, Deshmukh SV, Zielstorff M, Byford A, Chakravarthy K, Dorosh L, Rivkin A, Klappenbach J, Pan BS, Kariv I, Dinsmore C, Slipetz D, Dandliker PJ.

J Pharmacol Exp Ther. 2017 May;361(2):229-244. doi: 10.1124/jpet.116.239723. Epub 2017 Feb 13.


"Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors.

Sosale NG, Ivanovska II, Tsai RK, Swift J, Hsu JW, Alvey CM, Zoltick PW, Discher DE.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16080. doi: 10.1038/mtm.2016.80. eCollection 2016.


Nuclear constriction segregates mobile nuclear proteins away from chromatin.

Irianto J, Pfeifer CR, Bennett RR, Xia Y, Ivanovska IL, Liu AJ, Greenberg RA, Discher DE.

Mol Biol Cell. 2016 Dec 15;27(25):4011-4020. Epub 2016 Oct 26.


Nuclear lamins in cancer.

Irianto J, Pfeifer CR, Ivanovska IL, Swift J, Discher DE.

Cell Mol Bioeng. 2016 Jun;9(2):258-267. Epub 2016 Apr 18.


Stem cell mechanobiology: diverse lessons from bone marrow.

Ivanovska IL, Shin JW, Swift J, Discher DE.

Trends Cell Biol. 2015 Sep;25(9):523-32. doi: 10.1016/j.tcb.2015.04.003. Epub 2015 Jun 2. Review.


Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PC, Ivanovska IL, Discher DE.

J Cell Biol. 2014 Mar 3;204(5):669-82. doi: 10.1083/jcb.201308029. Epub 2014 Feb 24.


Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells.

Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE.

Cell Stem Cell. 2014 Jan 2;14(1):81-93. doi: 10.1016/j.stem.2013.10.009. Epub 2013 Nov 21.


Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.

Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, Rehfeldt F, Speicher DW, Discher DE.

Science. 2013 Aug 30;341(6149):1240104. doi: 10.1126/science.1240104.


Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates.

Shin JW, Swift J, Ivanovska I, Spinler KR, Buxboim A, Discher DE.

Differentiation. 2013 Oct;86(3):77-86. doi: 10.1016/j.diff.2013.05.001. Epub 2013 Jun 19. Review.


Probing the impact of loading rate on the mechanical properties of viral nanoparticles.

Snijder J, Ivanovska IL, Baclayon M, Roos WH, Wuite GJ.

Micron. 2012 Dec;43(12):1343-50. doi: 10.1016/j.micron.2012.04.011. Epub 2012 Apr 27.


Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma.

Ivanovska I, Zhang C, Liu AM, Wong KF, Lee NP, Lewis P, Philippar U, Bansal D, Buser C, Scott M, Mao M, Poon RT, Fan ST, Cleary MA, Luk JM, Dai H.

PLoS One. 2011;6(9):e24582. doi: 10.1371/journal.pone.0024582. Epub 2011 Sep 16.


Discrete fracture patterns of virus shells reveal mechanical building blocks.

Ivanovska IL, Miranda R, Carrascosa JL, Wuite GJ, Schmidt CF.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12611-6. doi: 10.1073/pnas.1105586108. Epub 2011 Jul 18.


Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.

Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE.

PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5.


DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival.

Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, Lee NP, Fan ST, Poon RT, Ivanovska I, Philippar U, Cleary MA, Buser CA, Shaw PM, Lee CN, Tenen DG, Dai H, Mao M.

J Biol Chem. 2011 Sep 2;286(35):30706-13. doi: 10.1074/jbc.M111.229831. Epub 2011 Jul 7.


Control of chromatin structure by spt6: different consequences in coding and regulatory regions.

Ivanovska I, Jacques PÉ, Rando OJ, Robert F, Winston F.

Mol Cell Biol. 2011 Feb;31(3):531-41. doi: 10.1128/MCB.01068-10. Epub 2010 Nov 22.


Effects of salts on internal DNA pressure and mechanical properties of phage capsids.

Evilevitch A, Roos WH, Ivanovska IL, Jeembaeva M, Jönsson B, Wuite GJ.

J Mol Biol. 2011 Jan 7;405(1):18-23. doi: 10.1016/j.jmb.2010.10.039. Epub 2010 Oct 28. Review.


Physical plasticity of the nucleus and its manipulation.

Ivanovska I, Swift J, Harada T, Pajerowski JD, Discher DE.

Methods Cell Biol. 2010;98:207-20. doi: 10.1016/S0091-679X(10)98009-6. Review.


Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

Buxboim A, Ivanovska IL, Discher DE.

J Cell Sci. 2010 Feb 1;123(Pt 3):297-308. doi: 10.1242/jcs.041186.


Characterization of microRNAs involved in embryonic stem cell states.

Stadler B, Ivanovska I, Mehta K, Song S, Nelson A, Tan Y, Mathieu J, Darby C, Blau CA, Ware C, Peters G, Miller DG, Shen L, Cleary MA, Ruohola-Baker H.

Stem Cells Dev. 2010 Jul;19(7):935-50. doi: 10.1089/scd.2009.0426.


microRNAs regulate human embryonic stem cell division.

Qi J, Yu JY, Shcherbata HR, Mathieu J, Wang AJ, Seal S, Zhou W, Stadler BM, Bourgin D, Wang L, Nelson A, Ware C, Raymond C, Lim LP, Magnus J, Ivanovska I, Diaz R, Ball A, Cleary MA, Ruohola-Baker H.

Cell Cycle. 2009 Nov 15;8(22):3729-41. Epub 2009 Nov 10.


Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.

Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, Choi YJ, Kleinhanz R, Shang J, Zhou YP, Howard AD, Zhang BB, Kendziorski C, Thornberry NA, Yandell BS, Schadt EE, Attie AD.

Mamm Genome. 2009 Aug;20(8):476-85. doi: 10.1007/s00335-009-9217-2.


Elastic properties of hollow colloidal particles.

Zoldesi CI, Ivanovska IL, Quilliet C, Wuite GJ, Imhof A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Nov;78(5 Pt 1):051401. Epub 2008 Nov 5.


Combinatorial microRNAs: working together to make a difference.

Ivanovska I, Cleary MA.

Cell Cycle. 2008 Oct;7(20):3137-42. Epub 2008 Oct 4. Review.


MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression.

Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM, Kobayashi SV, Lim L, Burchard J, Jackson AL, Linsley PS, Cleary MA.

Mol Cell Biol. 2008 Apr;28(7):2167-74. doi: 10.1128/MCB.01977-07. Epub 2008 Jan 22.


Internal DNA pressure modifies stability of WT phage.

Ivanovska I, Wuite G, Jönsson B, Evilevitch A.

Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9603-8. Epub 2007 May 29.


Viral capsids: mechanical characteristics, genome packaging and delivery mechanisms.

Roos WH, Ivanovska IL, Evilevitch A, Wuite GJ.

Cell Mol Life Sci. 2007 Jun;64(12):1484-97. Review.


Failure of viral shells.

Klug WS, Bruinsma RF, Michel JP, Knobler CM, Ivanovska IL, Schmidt CF, Wuite GJ.

Phys Rev Lett. 2006 Dec 1;97(22):228101. Epub 2006 Nov 27.


Anti-tumor therapeutic molecules that target the programmed cell death machinery.

Ivanovska I, Muhoro CN, Irusta PM.

Mini Rev Med Chem. 2006 Sep;6(9):1033-42. Review.


Histone modifications and the chromatin scaffold for meiotic chromosome architecture.

Ivanovska I, Orr-Weaver TL.

Cell Cycle. 2006 Sep;5(18):2064-71. Epub 2006 Sep 15. Review.


Mitochondrial factors with dual roles in death and survival.

Cheng WC, Berman SB, Ivanovska I, Jonas EA, Lee SJ, Chen Y, Kaczmarek LK, Pineda F, Hardwick JM.

Oncogene. 2006 Aug 7;25(34):4697-705. Review.


Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength.

Michel JP, Ivanovska IL, Gibbons MM, Klug WS, Knobler CM, Wuite GJ, Schmidt CF.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6184-9. Epub 2006 Apr 10.


A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes.

Ivanovska I, Khandan T, Ito T, Orr-Weaver TL.

Genes Dev. 2005 Nov 1;19(21):2571-82. Epub 2005 Oct 17.


Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.

Jonas EA, Hickman JA, Chachar M, Polster BM, Brandt TA, Fannjiang Y, Ivanovska I, Basañez G, Kinnally KW, Zimmerberg J, Hardwick JM, Kaczmarek LK.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13590-5. Epub 2004 Sep 1.


BAD is a pro-survival factor prior to activation of its pro-apoptotic function.

Seo SY, Chen YB, Ivanovska I, Ranger AM, Hong SJ, Dawson VL, Korsmeyer SJ, Bellows DS, Fannjiang Y, Hardwick JM.

J Biol Chem. 2004 Oct 1;279(40):42240-9. Epub 2004 Jul 1.


Bacteriophage capsids: tough nanoshells with complex elastic properties.

Ivanovska IL, de Pablo PJ, Ibarra B, Sgalari G, MacKintosh FC, Carrascosa JL, Schmidt CF, Wuite GJ.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7600-5. Epub 2004 May 7.


The Drosophila MOS ortholog is not essential for meiosis.

Ivanovska I, Lee E, Kwan KM, Fenger DD, Orr-Weaver TL.

Curr Biol. 2004 Jan 6;14(1):75-80.


Regulation of cell death in the lymphoid system by Bcl-2 family proteins.

Ivanovska I, Galonek HL, Hildeman DA, Hardwick JM.

Acta Haematol. 2004;111(1-2):42-55. Review.


Functional interaction between the PKC1 pathway and CDC31 network of SPB duplication genes.

Khalfan W, Ivanovska I, Rose MD.

Genetics. 2000 Aug;155(4):1543-59.


A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch.

Kaye FJ, Modi S, Ivanovska I, Koonin EV, Thress K, Kubo A, Kornbluth S, Rose MD.

FEBS Lett. 2000 Feb 11;467(2-3):348-55.


SLG1 plays a role during G1 in the decision to enter or exit the cell cycle.

Ivanovska I, Rose MD.

Mol Gen Genet. 2000 Jan;262(6):1147-56.


Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center.

Biggins S, Ivanovska I, Rose MD.

J Cell Biol. 1996 Jun;133(6):1331-46.

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