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Items: 29

1.

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A.

EMBO J. 2018 May 15. pii: e98133. doi: 10.15252/embj.201798133. [Epub ahead of print]

2.

Multimodal label-free ex vivo imaging using a dual-wavelength microscope with axial chromatic aberration compensation.

Filippi A, Dal Sasso E, Iop L, Armani A, Gintoli M, Sandri M, Gerosa G, Romanato F, Borile G.

J Biomed Opt. 2018 Mar;23(9):1-9. doi: 10.1117/1.JBO.23.9.091403.

PMID:
29516689
3.

Native Bovine and Porcine Pericardia Respond to Load With Additive Recruitment of Collagen Fibers.

Bagno A, Aguiari P, Fiorese M, Iop L, Spina M, Gerosa G.

Artif Organs. 2017 Dec 27. doi: 10.1111/aor.13065. [Epub ahead of print]

PMID:
29280157
4.

The Rapidly Evolving Concept of Whole Heart Engineering.

Iop L, Dal Sasso E, Menabò R, Di Lisa F, Gerosa G.

Stem Cells Int. 2017;2017:8920940. doi: 10.1155/2017/8920940. Epub 2017 Nov 9. Review.

5.

A sterilization method for decellularized xenogeneic cardiovascular scaffolds.

Fidalgo C, Iop L, Sciro M, Harder M, Mavrilas D, Korossis S, Bagno A, Palù G, Aguiari P, Gerosa G.

Acta Biomater. 2018 Feb;67:282-294. doi: 10.1016/j.actbio.2017.11.035. Epub 2017 Dec 2.

PMID:
29183849
6.

The Light and Shadow of Senescence and Inflammation in Cardiovascular Pathology and Regenerative Medicine.

Iop L, Dal Sasso E, Schirone L, Forte M, Peruzzi M, Cavarretta E, Palmerio S, Gerosa G, Sciarretta S, Frati G.

Mediators Inflamm. 2017;2017:7953486. doi: 10.1155/2017/7953486. Epub 2017 Oct 8. Review.

7.

The Vietnamese pig as a translational animal model to evaluate tissue engineered heart valves: promising early experience.

Gallo M, Poser H, Bottio T, Bonetti A, Franci P, Naso F, Buratto E, Zanella F, Perona G, Dal Lin C, Bianco R, Spina M, Busetto R, Marchini M, Ortolani F, Iop L, Gerosa G.

Int J Artif Organs. 2017 May 9;40(4):142-149. doi: 10.5301/ijao.5000568. Epub 2017 Mar 27.

PMID:
28362047
8.

Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative for Heart Valve Replacement: In Vitro Assessment Before Clinical Translation.

Iop L, Paolin A, Aguiari P, Trojan D, Cogliati E, Gerosa G.

J Cardiovasc Transl Res. 2017 Apr;10(2):93-103. doi: 10.1007/s12265-017-9738-0. Epub 2017 Mar 9.

PMID:
28281241
9.

In vitro comparative assessment of decellularized bovine pericardial patches and commercial bioprosthetic heart valves.

Aguiari P, Iop L, Favaretto F, Fidalgo CM, Naso F, Milan G, Vindigni V, Spina M, Bassetto F, Bagno A, Vettor R, Gerosa G.

Biomed Mater. 2017 Feb 3;12(1):015021. doi: 10.1088/1748-605X/aa5644.

PMID:
28157718
10.

Decellularized aortic conduits: could their cryopreservation affect post-implantation outcomes? A morpho-functional study on porcine homografts.

Gallo M, Bonetti A, Poser H, Naso F, Bottio T, Bianco R, Paolin A, Franci P, Busetto R, Frigo AC, Buratto E, Spina M, Marchini M, Ortolani F, Iop L, Gerosa G.

Heart Vessels. 2016 Nov;31(11):1862-1873. Epub 2016 Apr 26.

PMID:
27115146
11.

Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells.

Di Liddo R, Aguiari P, Barbon S, Bertalot T, Mandoli A, Tasso A, Schrenk S, Iop L, Gandaglia A, Parnigotto PP, Conconi MT, Gerosa G.

Int J Nanomedicine. 2016 Oct 12;11:5041-5055. eCollection 2016.

12.

Guided tissue regeneration in heart valve replacement: from preclinical research to first-in-human trials.

Iop L, Gerosa G.

Biomed Res Int. 2015;2015:432901. doi: 10.1155/2015/432901. Epub 2015 Oct 1. Review.

13.

Mechanical testing of pericardium for manufacturing prosthetic heart valves.

Aguiari P, Fiorese M, Iop L, Gerosa G, Bagno A.

Interact Cardiovasc Thorac Surg. 2016 Jan;22(1):72-84. doi: 10.1093/icvts/ivv282. Epub 2015 Oct 21. Review.

PMID:
26489665
14.

Present and future perspectives on total artificial hearts.

Gerosa G, Scuri S, Iop L, Torregrossa G.

Ann Cardiothorac Surg. 2014 Nov;3(6):595-602. doi: 10.3978/j.issn.2225-319X.2014.09.05.

15.

Extracellular pyrophosphate is reduced in aortic interstitial valve cells acquiring a calcifying profile: implications for aortic valve calcification.

Rattazzi M, Bertacco E, Iop L, D'Andrea S, Puato M, Buso G, Causin V, Gerosa G, Faggin E, Pauletto P.

Atherosclerosis. 2014 Dec;237(2):568-76. doi: 10.1016/j.atherosclerosis.2014.10.027. Epub 2014 Oct 22.

PMID:
25463090
16.

Cellular, molecular, genomic changes occurring in the heart under mechanical circulatory support.

Gallo M, Tarzia V, Iop L, Bejko J, Bortolussi G, Bianco R, Bottio T, Gerosa G.

Ann Cardiothorac Surg. 2014 Sep;3(5):496-504. doi: 10.3978/j.issn.2225-319X.2014.08.23. No abstract available.

17.

Decellularized allogeneic heart valves demonstrate self-regeneration potential after a long-term preclinical evaluation.

Iop L, Bonetti A, Naso F, Rizzo S, Cagnin S, Bianco R, Dal Lin C, Martini P, Poser H, Franci P, Lanfranchi G, Busetto R, Spina M, Basso C, Marchini M, Gandaglia A, Ortolani F, Gerosa G.

PLoS One. 2014 Jun 18;9(6):e99593. doi: 10.1371/journal.pone.0099593. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e107601.

18.

Are FDA and CE sacrificing safety for a faster commercialization of xenogeneic tissue devices? Unavoidable need for legislation in decellularized tissue manufacturing.

Naso F, Iop L, Spina M, Gerosa G.

Tissue Antigens. 2014 Mar;83(3):193-4. doi: 10.1111/tan.12275. Epub 2014 Jan 7. No abstract available.

PMID:
24397352
19.

First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprostheses.

Naso F, Gandaglia A, Bottio T, Tarzia V, Nottle MB, d'Apice AJ, Cowan PJ, Cozzi E, Galli C, Lagutina I, Lazzari G, Iop L, Spina M, Gerosa G.

Xenotransplantation. 2013 Jul-Aug;20(4):252-61. doi: 10.1111/xen.12044. Epub 2013 Jul 19.

PMID:
23865597
20.

Alpha-Gal detectors in xenotransplantation research: a word of caution.

Naso F, Gandaglia A, Iop L, Spina M, Gerosa G.

Xenotransplantation. 2012 Jul-Aug;19(4):215-20. doi: 10.1111/j.1399-3089.2012.00714.x. Review.

PMID:
22909134
21.

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia.

Jung CB, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL.

EMBO Mol Med. 2012 Mar;4(3):180-91. doi: 10.1002/emmm.201100194. Epub 2012 Jan 25.

22.

First quantitative assay of alpha-Gal in soft tissues: presence and distribution of the epitope before and after cell removal from xenogeneic heart valves.

Naso F, Gandaglia A, Iop L, Spina M, Gerosa G.

Acta Biomater. 2011 Apr;7(4):1728-34. doi: 10.1016/j.actbio.2010.11.030. Epub 2010 Nov 29.

PMID:
21118731
23.

Proteomic analysis of clonal interstitial aortic valve cells acquiring a pro-calcific profile.

Bertacco E, Millioni R, Arrigoni G, Faggin E, Iop L, Puato M, Pinna LA, Tessari P, Pauletto P, Rattazzi M.

J Proteome Res. 2010 Nov 5;9(11):5913-21. doi: 10.1021/pr100682g. Epub 2010 Oct 18.

PMID:
20825172
24.

Human bone marrow-derived CD133(+) cells delivered to a collagen patch on cryoinjured rat heart promote angiogenesis and arteriogenesis.

Pozzobon M, Bollini S, Iop L, De Gaspari P, Chiavegato A, Rossi CA, Giuliani S, Fascetti Leon F, Elvassore N, Sartore S, De Coppi P.

Cell Transplant. 2010;19(10):1247-60. doi: 10.3727/096368910X505864. Epub 2010 May 4.

PMID:
20447342
25.

The influence of heart valve leaflet matrix characteristics on the interaction between human mesenchymal stem cells and decellularized scaffolds.

Iop L, Renier V, Naso F, Piccoli M, Bonetti A, Gandaglia A, Pozzobon M, Paolin A, Ortolani F, Marchini M, Spina M, De Coppi P, Sartore S, Gerosa G.

Biomaterials. 2009 Sep;30(25):4104-16. doi: 10.1016/j.biomaterials.2009.04.031. Epub 2009 May 29.

PMID:
19481252
26.

Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate.

Rattazzi M, Iop L, Faggin E, Bertacco E, Zoppellaro G, Baesso I, Puato M, Torregrossa G, Fadini GP, Agostini C, Gerosa G, Sartore S, Pauletto P.

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2165-72. doi: 10.1161/ATVBAHA.108.174342. Epub 2008 Oct 2.

27.

Different cardiovascular potential of adult- and fetal-type mesenchymal stem cells in a rat model of heart cryoinjury.

Iop L, Chiavegato A, Callegari A, Bollini S, Piccoli M, Pozzobon M, Rossi CA, Calamelli S, Chiavegato D, Gerosa G, De Coppi P, Sartore S.

Cell Transplant. 2008;17(6):679-94.

PMID:
18819256
28.

Neovascularization induced by porous collagen scaffold implanted on intact and cryoinjured rat hearts.

Callegari A, Bollini S, Iop L, Chiavegato A, Torregrossa G, Pozzobon M, Gerosa G, De Coppi P, Elvassore N, Sartore S.

Biomaterials. 2007 Dec;28(36):5449-61. Epub 2007 Oct 1.

PMID:
17905428
29.

Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat.

Chiavegato A, Bollini S, Pozzobon M, Callegari A, Gasparotto L, Taiani J, Piccoli M, Lenzini E, Gerosa G, Vendramin I, Cozzi E, Angelini A, Iop L, Zanon GF, Atala A, De Coppi P, Sartore S.

J Mol Cell Cardiol. 2007 Apr;42(4):746-59. Epub 2006 Dec 23.

PMID:
17300799

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