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Development of a prediction tool for patients presenting with acute cough in primary care: a prognostic study spanning six European countries.

Bruyndonckx R, Hens N, Verheij TJ, Aerts M, Ieven M, Butler CC, Little P, Goossens H, Coenen S; GRACE project group.

Br J Gen Pract. 2018 Apr 9. pii: bjgp18X695789. doi: 10.3399/bjgp18X695789. [Epub ahead of print]


Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries.

Ieven M, Coenen S, Loens K, Lammens C, Coenjaerts F, Vanderstraeten A, Henriques-Normark B, Crook D, Huygen K, Butler CC, Verheij TJM, Little P, Zlateva K, van Loon A, Claas ECJ, Goossens H; GRACE consortium.

Clin Microbiol Infect. 2018 Feb 12. pii: S1198-743X(18)30152-6. doi: 10.1016/j.cmi.2018.02.004. [Epub ahead of print]


Human papillomavirus genotype and viral load agreement between paired first-void urine and clinician-collected cervical samples.

Van Keer S, Tjalma WAA, Pattyn J, Biesmans S, Pieters Z, Van Ostade X, Ieven M, Van Damme P, Vorsters A.

Eur J Clin Microbiol Infect Dis. 2018 Feb 7. doi: 10.1007/s10096-017-3179-1. [Epub ahead of print]


Laboratory preparedness and response with a focus on arboviruses in Europe.

Reusken CB, Ieven M, Sigfrid L, Eckerle I, Koopmans M.

Clin Microbiol Infect. 2018 Mar;24(3):221-228. doi: 10.1016/j.cmi.2017.12.010. Epub 2017 Dec 20. Review.


Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood-brain barrier dysfunction.

Mertens JC, Leenaerts D, Brouns R, Engelborghs S, Ieven M, De Deyn PP, Lambeir AM, Hendriks D.

J Thromb Haemost. 2018 Feb;16(2):342-348. doi: 10.1111/jth.13914. Epub 2017 Dec 26.


Amoxicillin for acute lower respiratory tract infection in primary care: subgroup analysis by bacterial and viral aetiology.

Bruyndonckx R, Stuart B, Little P, Hens N, Ieven M, Butler CC, Verheij T, Goossens H, Coenen S; GRACE project group.

Clin Microbiol Infect. 2017 Nov 3. pii: S1198-743X(17)30626-2. doi: 10.1016/j.cmi.2017.10.032. [Epub ahead of print]


First-void urine: A potential biomarker source for triage of high-risk human papillomavirus infected women.

Van Keer S, Pattyn J, Tjalma WAA, Van Ostade X, Ieven M, Van Damme P, Vorsters A.

Eur J Obstet Gynecol Reprod Biol. 2017 Sep;216:1-11. doi: 10.1016/j.ejogrb.2017.06.036. Epub 2017 Jun 27. Review.


Emergence of antimicrobial resistance to Pseudomonas aeruginosa in the intensive care unit: association with the duration of antibiotic exposure and mode of administration.

Yusuf E, Van Herendael B, Verbrugghe W, Ieven M, Goovaerts E, Bergs K, Wouters K, Jorens PG, Goossens H.

Ann Intensive Care. 2017 Dec;7(1):72. doi: 10.1186/s13613-017-0296-z. Epub 2017 Jun 29.


The first clonal spread of vanA-positive Enterococcus raffinosus in a nursing home.

Yusuf E, Loens K, Jans B, Cox P, Ieven M, Goossens H.

J Hosp Infect. 2017 May;96(1):72-74. doi: 10.1016/j.jhin.2017.03.008. Epub 2017 Mar 11. No abstract available.


Disease Course of Lower Respiratory Tract Infection With a Bacterial Cause.

Teepe J, Broekhuizen BD, Loens K, Lammens C, Ieven M, Goossens H, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Verheij T; GRACE Consortium.

Ann Fam Med. 2016 Nov;14(6):534-539. doi: 10.1370/afm.1974.


The endotracheal tube microbiome associated with Pseudomonas aeruginosa or Staphylococcus epidermidis.

Hotterbeekx A, Xavier BB, Bielen K, Lammens C, Moons P, Schepens T, Ieven M, Jorens PG, Goossens H, Kumar-Singh S, Malhotra-Kumar S.

Sci Rep. 2016 Nov 4;6:36507. doi: 10.1038/srep36507.


Predicting the presence of bacterial pathogens in the airways of primary care patients with acute cough.

Teepe J, Broekhuizen BD, Loens K, Lammens C, Ieven M, Goossens H, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Verheij TJ; GRACE Consortium.

CMAJ. 2016 Oct 24. pii: cmaj.151364. [Epub ahead of print]


Sepsis Caused by Achromobacter Xylosoxidans in a Child with Cystic Fibrosis and Severe Lung Disease.

Stobbelaar K, Van Hoorenbeeck K, Lequesne M, De Dooy J, Ho E, Vlieghe E, Ieven M, Verhulst S.

Am J Case Rep. 2016 Aug 8;17:562-6.


Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections: a randomized, placebo-controlled study.

Malhotra-Kumar S, Van Heirstraeten L, Coenen S, Lammens C, Adriaenssens N, Kowalczyk A, Godycki-Cwirko M, Bielicka Z, Hupkova H, Lannering C, Mölstad S, Fernandez-Vandellos P, Torres A, Parizel M, Ieven M, Butler CC, Verheij T, Little P, Goossens H; GRACE study group.

J Antimicrob Chemother. 2016 Nov;71(11):3258-3267. Epub 2016 Jun 26.


Long-Term Follow-up of HPV Infection Using Urine and Cervical Quantitative HPV DNA Testing.

Vorsters A, Van Keer S, Biesmans S, Hens A, De Coster I, Goossens H, Ieven M, Van Damme P.

Int J Mol Sci. 2016 May 17;17(5). pii: E750. doi: 10.3390/ijms17050750.


Characterizing the in vitro biofilm phenotype of Staphylococcus epidermidis isolates from central venous catheters.

Van Kerckhoven M, Hotterbeekx A, Lanckacker E, Moons P, Lammens C, Kerstens M, Ieven M, Delputte P, Jorens PG, Malhotra-Kumar S, Goossens H, Maes L, Cos P.

J Microbiol Methods. 2016 Aug;127:95-101. doi: 10.1016/j.mimet.2016.05.009. Epub 2016 May 16.


Evaluation of the Bio-Rad Dx CT/NG/MG® assay for simultaneous detection of Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium in urine.

Ursi D, Crucitti T, Smet H, Ieven M.

Eur J Clin Microbiol Infect Dis. 2016 Jul;35(7):1159-63. doi: 10.1007/s10096-016-2646-4. Epub 2016 Apr 26.


Mycoplasma pneumoniae: Current Knowledge on Nucleic Acid Amplification Techniques and Serological Diagnostics.

Loens K, Ieven M.

Front Microbiol. 2016 Mar 31;7:448. doi: 10.3389/fmicb.2016.00448. eCollection 2016. Review.


Cellular Interferon Gamma and Granzyme B Responses to Cytomegalovirus-pp65 and Influenza N1 Are Positively Associated in Elderly.

Theeten H, Mathei C, Peeters K, Ogunjimi B, Goossens H, Ieven M, Van Damme P, Cools N.

Viral Immunol. 2016 Apr;29(3):169-75. doi: 10.1089/vim.2015.0071. Epub 2016 Mar 22.


Amoxicillin for clinically unsuspected pneumonia in primary care: subgroup analysis.

Teepe J, Little P, Elshof N, Broekhuizen BD, Moore M, Stuart B, Butler CC, Hood K, Ieven M, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Eur Respir J. 2016 Jan;47(1):327-30. doi: 10.1183/13993003.00611-2015. Epub 2015 Nov 5. No abstract available.


Prevalence, diagnosis, and disease course of pertussis in adults with acute cough: a prospective, observational study in primary care.

Teepe J, Broekhuizen BD, Ieven M, Loens K, Huygen K, Kretzschmar M, de Melker H, Butler CC, Little P, Stuart B, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2015 Oct;65(639):e662-7. doi: 10.3399/bjgp15X686917.


Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care.

van Vugt SF, Broekhuizen BD, Zuithoff NP, van Essen GA, Ebell MH, Coenen S, Ieven M, Lammens C, Goossens H, Butler CC, Hood K, Little P, Verheij TJ; GRACE Consortium.

Fam Pract. 2015 Aug;32(4):408-14. doi: 10.1093/fampra/cmv039. Epub 2015 Jun 4.


The added diagnostic value of five different C-reactive protein point-of-care test devices in detecting pneumonia in primary care: A nested case-control study.

Minnaard MC, van de Pol AC, de Groot JA, De Wit NJ, Hopstaken RM, van Delft S, Goossens H, Ieven M, Lammens C, Little P, Butler CC, Broekhuizen BD, Verheij TJ.

Scand J Clin Lab Invest. 2015 Jul;75(4):291-5. doi: 10.3109/00365513.2015.1006136. Epub 2015 Feb 27.


Identification of a novel human rhinovirus C type by antibody capture VIDISCA-454.

Jazaeri Farsani SM, Oude Munnink BB, Canuti M, Deijs M, Cotten M, Jebbink MF, Verhoeven J, Kellam P, Loens K, Goossens H, Ieven M, van der Hoek L.

Viruses. 2015 Jan 19;7(1):239-51. doi: 10.3390/v7010239.


Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses.

Farsani SM, Deijs M, Dijkman R, Molenkamp R, Jeeninga RE, Ieven M, Goossens H, van der Hoek L.

Influenza Other Respir Viruses. 2015 Jan;9(1):51-7. doi: 10.1111/irv.12297. Epub 2014 Dec 8.


Whole genome mapping as a fast-track tool to assess genomic stability of sequenced Staphylococcus aureus strains.

Sabirova JS, Xavier BB, Ieven M, Goossens H, Malhotra-Kumar S.

BMC Res Notes. 2014 Oct 8;7:704. doi: 10.1186/1756-0500-7-704.


Metagenomic analysis of a sample from a patient with respiratory tract infection reveals the presence of a γ-papillomavirus.

Canuti M, Deijs M, Jazaeri Farsani SM, Holwerda M, Jebbink MF, de Vries M, van Vugt S, Brugman C, Verheij T, Lammens C, Goossens H, Loens K, Ieven M, van der Hoek L.

Front Microbiol. 2014 Jul 8;5:347. doi: 10.3389/fmicb.2014.00347. eCollection 2014.


Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNA-transfected dendritic cells.

Van Craenenbroeck AH, Smits EL, Anguille S, Van de Velde A, Stein B, Braeckman T, Van Camp K, Nijs G, Ieven M, Goossens H, Berneman ZN, Van Tendeloo VF, Verpooten GA, Van Damme P, Cools N.

Transplantation. 2015 Jan;99(1):120-7. doi: 10.1097/TP.0000000000000272.


Complete Genome Sequences of Two Prolific Biofilm-Forming Staphylococcus aureus Isolates Belonging to USA300 and EMRSA-15 Clonal Lineages.

Sabirova JS, Xavier BB, Hernalsteens JP, De Greve H, Ieven M, Goossens H, Malhotra-Kumar S.

Genome Announc. 2014 Jun 26;2(3). pii: e00610-14. doi: 10.1128/genomeA.00610-14.


Optimization of HPV DNA detection in urine by improving collection, storage, and extraction.

Vorsters A, Van den Bergh J, Micalessi I, Biesmans S, Bogers J, Hens A, De Coster I, Ieven M, Van Damme P.

Eur J Clin Microbiol Infect Dis. 2014 Nov;33(11):2005-14. doi: 10.1007/s10096-014-2147-2. Epub 2014 Jun 12.


Prolonged shedding of rhinovirus and re-infection in adults with respiratory tract illness.

Zlateva KT, de Vries JJ, Coenjaerts FE, van Loon AM, Verheij T, Little P, Butler CC, Goossens H, Ieven M, Claas EC; GRACE Study Group.

Eur Respir J. 2014 Jul;44(1):169-77. doi: 10.1183/09031936.00172113. Epub 2014 May 29. Erratum in: Eur Respir J. 2014 Aug;44(2):556.


Pseudo-outbreak of pre-extensively drug-resistant (Pre-XDR) tuberculosis in Kinshasa: collateral damage caused by false detection of fluoroquinolone resistance by GenoType MTBDRsl.

Kaswa MK, Aloni M, Nkuku L, Bakoko B, Lebeke R, Nzita A, Muyembe JJ, de Jong BC, de Rijk P, Verhaegen J, Boelaert M, Ieven M, Van Deun A.

J Clin Microbiol. 2014 Aug;52(8):2876-80. doi: 10.1128/JCM.00398-14. Epub 2014 May 28.


Is acyclovir effective among critically ill patients with herpes simplex in the respiratory tract?

Traen S, Bochanen N, Ieven M, Schepens T, Bruynseels P, Verbrugghe W, Jorens PG.

J Clin Virol. 2014 Jul;60(3):215-21. doi: 10.1016/j.jcv.2014.04.010. Epub 2014 Apr 18.


Autologous antibody capture to enrich immunogenic viruses for viral discovery.

Oude Munnink BB, Jazaeri Farsani SM, Deijs M, Jonkers J, Verhoeven JT, Ieven M, Goossens H, de Jong MD, Berkhout B, Loens K, Kellam P, Bakker M, Canuti M, Cotten M, van der Hoek L.

PLoS One. 2013 Nov 4;8(11):e78454. doi: 10.1371/journal.pone.0078454. eCollection 2013.


Fourth Belgian multicentre survey of antibiotic susceptibility of anaerobic bacteria.

Wybo I, Van den Bossche D, Soetens O, Vekens E, Vandoorslaer K, Claeys G, Glupczynski Y, Ieven M, Melin P, Nonhoff C, Rodriguez-Villalobos H, Verhaegen J, Piérard D.

J Antimicrob Chemother. 2014 Jan;69(1):155-61. doi: 10.1093/jac/dkt344. Epub 2013 Sep 5.


IFITM3 and susceptibility to respiratory viral infections in the community.

Mills TC, Rautanen A, Elliott KS, Parks T, Naranbhai V, Ieven MM, Butler CC, Little P, Verheij T, Garrard CS, Hinds C, Goossens H, Chapman S, Hill AV.

J Infect Dis. 2014 Apr 1;209(7):1028-31. doi: 10.1093/infdis/jit468. Epub 2013 Aug 30.


Use of serum C reactive protein and procalcitonin concentrations in addition to symptoms and signs to predict pneumonia in patients presenting to primary care with acute cough: diagnostic study.

van Vugt SF, Broekhuizen BD, Lammens C, Zuithoff NP, de Jong PA, Coenen S, Ieven M, Butler CC, Goossens H, Little P, Verheij TJ; GRACE consortium.

BMJ. 2013 Apr 30;346:f2450. doi: 10.1136/bmj.f2450.


Staphylococcus jettensis sp. nov., a coagulase-negative staphylococcal species isolated from human clinical specimens.

De Bel A, Van Hoorde K, Wybo I, Vandoorslaer K, Echahidi F, De Brandt E, Schumann P, Ieven M, Soetens O, Piérard D, Vandamme P.

Int J Syst Evol Microbiol. 2013 Sep;63(Pt 9):3250-6. doi: 10.1099/ijs.0.044438-0. Epub 2013 Mar 1.


Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism.

Dijkman R, Jebbink MF, Koekkoek SM, Deijs M, Jónsdóttir HR, Molenkamp R, Ieven M, Goossens H, Thiel V, van der Hoek L.

J Virol. 2013 Jun;87(11):6081-90. doi: 10.1128/JVI.03368-12. Epub 2013 Feb 20.


A tropical diabetic foot.

Henckaerts L, Naesens R, Vlieghe E, Jansens H, Gielen J, Ieven M, Moorkens G.

Acta Clin Belg. 2012 Sep-Oct;67(5):362-4.


Cost analysis in favor of a combined approach for cytomegalovirus after kidney transplantation: a single-center experience.

Hellemans R, Beutels P, Ieven M, Verpooten GA, Bosmans JL.

Transpl Infect Dis. 2013 Feb;15(1):70-8. doi: 10.1111/tid.12023. Epub 2012 Nov 23.


European quality clearance of new microbiological diagnostics.

Ieven M, Finch R, van Belkum A.

Clin Microbiol Infect. 2013 Jan;19(1):29-38. doi: 10.1111/1469-0691.12052. Epub 2012 Oct 29. Review.


No novel coronaviruses identified in a large collection of human nasopharyngeal specimens using family-wide CODEHOP-based primers.

Zlateva KT, Coenjaerts FE, Crusio KM, Lammens C, Leus F, Viveen M, Ieven M, Spaan WJ, Claas EC, Gorbalenya AE.

Arch Virol. 2013 Jan;158(1):251-5. doi: 10.1007/s00705-012-1487-4. Epub 2012 Sep 28.


A real-time PCR approach based on SPF10 primers and the INNO-LiPA HPV Genotyping Extra assay for the detection and typing of human papillomavirus.

Micalessi MI, Boulet GA, Vorsters A, De Wit K, Jannes G, Mijs W, Ieven M, Van Damme P, Bogers JJ.

J Virol Methods. 2013 Jan;187(1):166-71. doi: 10.1016/j.jviromet.2012.09.013. Epub 2012 Sep 24.


The first complete genome sequences of clinical isolates of human coronavirus 229E.

Farsani SM, Dijkman R, Jebbink MF, Goossens H, Ieven M, Deijs M, Molenkamp R, van der Hoek L.

Virus Genes. 2012 Dec;45(3):433-9. doi: 10.1007/s11262-012-0807-9. Epub 2012 Aug 25.


Continuous infusion of antibiotics in the critically ill: The new holy grail for beta-lactams and vancomycin?

Van Herendael B, Jeurissen A, Tulkens PM, Vlieghe E, Verbrugghe W, Jorens PG, Ieven M.

Ann Intensive Care. 2012 Jul 2;2(1):22. doi: 10.1186/2110-5820-2-22.


Bench-to-bedside review: Rapid molecular diagnostics for bloodstream infection--a new frontier?

Afshari A, Schrenzel J, Ieven M, Harbarth S.

Crit Care. 2012 May 29;16(3):222. doi: 10.1186/cc11202. Review.


WITHDRAWN: A real-time PCR approach based on SPF10 primers and the INNO-LiPA HPV Genotyping Extra assay for the detection and typing of human papillomavirus.

Micalessi MI, Boulet GA, Vorsters A, De Wit K, Jannes G, Mijs W, Ieven M, Van Damme P, Bogers JJ.

J Virol Methods. 2012 May 22. [Epub ahead of print]


High susceptibility to cytomegalovirus infection of pregnant women in Flanders, Belgium.

Leuridan E, Ieven M, Hens N, Van Damme P.

Facts Views Vis Obgyn. 2012;4(2):76-81.

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