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Items: 1 to 50 of 77

1.

Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.

Hino K, Horigome K, Nishio M, Komura S, Nagata S, Zhao C, Jin Y, Kawakami K, Yamada Y, Ohta A, Toguchida J, Ikeya M.

J Clin Invest. 2017 Sep 1;127(9):3339-3352. doi: 10.1172/JCI93521. Epub 2017 Jul 31.

2.

Characterization of Mesenchymal Stem Cell-Like Cells Derived From Human iPSCs via Neural Crest Development and Their Application for Osteochondral Repair.

Chijimatsu R, Ikeya M, Yasui Y, Ikeda Y, Ebina K, Moriguchi Y, Shimomura K, Hart DA, Hideki Y, Norimasa N.

Stem Cells Int. 2017;2017:1960965. doi: 10.1155/2017/1960965. Epub 2017 May 10.

3.

SOX10-Nano-Lantern Reporter Human iPS Cells; A Versatile Tool for Neural Crest Research.

Horikiri T, Ohi H, Shibata M, Ikeya M, Ueno M, Sotozono C, Kinoshita S, Sato T.

PLoS One. 2017 Jan 20;12(1):e0170342. doi: 10.1371/journal.pone.0170342. eCollection 2017.

4.

BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.

Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13057-13062. Epub 2016 Oct 28.

5.

[Application of disease-specific iPS cells for intractable diseases-from pathomechanisms to drug discovery].

Toguchida J, Hino K, Ikeya M.

Clin Calcium. 2016 Apr;26(4):593-600. doi: CliCa1604593600. Japanese.

PMID:
27013631
6.

Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives.

Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Xiang L, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K.

Methods. 2016 May 15;101:43-55. doi: 10.1016/j.ymeth.2015.12.012. Epub 2015 Dec 18.

7.

Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.

Hino K, Ikeya M, Horigome K, Matsumoto Y, Ebise H, Nishio M, Sekiguchi K, Shibata M, Nagata S, Matsuda S, Toguchida J.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15438-43. doi: 10.1073/pnas.1510540112. Epub 2015 Nov 30.

8.

SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.

Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T Jr, Toguchida J.

PLoS One. 2015 Nov 16;10(11):e0142991. doi: 10.1371/journal.pone.0142991. eCollection 2015.

9.

Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.

Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J.

PLoS One. 2015 Jul 10;10(7):e0131998. doi: 10.1371/journal.pone.0131998. eCollection 2015.

10.

New Protocol to Optimize iPS Cells for Genome Analysis of Fibrodysplasia Ossificans Progressiva.

Matsumoto Y, Ikeya M, Hino K, Horigome K, Fukuta M, Watanabe M, Nagata S, Yamamoto T, Otsuka T, Toguchida J.

Stem Cells. 2015 Jun;33(6):1730-42. doi: 10.1002/stem.1981.

11.

Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.

Fukuta M, Nakai Y, Kirino K, Nakagawa M, Sekiguchi K, Nagata S, Matsumoto Y, Yamamoto T, Umeda K, Heike T, Okumura N, Koizumi N, Sato T, Nakahata T, Saito M, Otsuka T, Kinoshita S, Ueno M, Ikeya M, Toguchida J.

PLoS One. 2014 Dec 2;9(12):e112291. doi: 10.1371/journal.pone.0112291. eCollection 2014.

12.

Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.

Yokoyama K, Ikeya M, Umeda K, Oda H, Nodomi S, Nasu A, Matsumoto Y, Izawa K, Horigome K, Kusaka T, Tanaka T, Saito MK, Yasumi T, Nishikomori R, Ohara O, Nakayama N, Nakahata T, Heike T, Toguchida J.

Arthritis Rheumatol. 2015 Jan;67(1):302-14. doi: 10.1002/art.38912.

13.

Orai-2 is localized on secretory granules and regulates antigen-evoked Ca²⁺ mobilization and exocytosis in mast cells.

Ikeya M, Yamanoue K, Mochizuki Y, Konishi H, Tadokoro S, Tanaka M, Suzuki R, Hirashima N.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):62-7. doi: 10.1016/j.bbrc.2014.07.060. Epub 2014 Jul 17.

PMID:
25044118
14.

Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation.

Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC.

Orphanet J Rare Dis. 2013 Dec 9;8:190. doi: 10.1186/1750-1172-8-190.

15.

Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro.

Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe K, Kimura E, Sakurai H.

PLoS One. 2013 Apr 23;8(4):e61540. doi: 10.1371/journal.pone.0061540. Print 2013.

16.

Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin.

Nasu A, Ikeya M, Yamamoto T, Watanabe A, Jin Y, Matsumoto Y, Hayakawa K, Amano N, Sato S, Osafune K, Aoyama T, Nakamura T, Kato T, Toguchida J.

PLoS One. 2013;8(1):e53771. doi: 10.1371/journal.pone.0053771. Epub 2013 Jan 31.

17.

Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells.

Hayakawa K, Ikeya M, Fukuta M, Woltjen K, Tamaki S, Takahara N, Kato T Jr, Sato S, Otsuka T, Toguchida J.

Biochem Biophys Res Commun. 2013 Mar 22;432(4):713-9. doi: 10.1016/j.bbrc.2013.01.003. Epub 2013 Jan 10.

PMID:
23313505
18.

Unusual Childhood Waking as a Possible Precursor of the 1995 Kobe Earthquake.

Ikeya M, Whitehead NE.

Animals (Basel). 2013 Mar 5;3(1):228-37. doi: 10.3390/ani3010228.

19.

Lateral medullary syndrome in a boy with hereditary dysfibrinogenemia.

Kibe T, Ikeya M, Yokochi K, Okumura N.

Brain Dev. 2012 Nov;34(10):857-60. doi: 10.1016/j.braindev.2012.02.010. Epub 2012 Mar 24.

PMID:
22449744
20.

Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors.

Ikeya M, Fukushima K, Kawada M, Onishi S, Furuta Y, Yonemura S, Kitamura T, Nosaka T, Sasai Y.

Dev Biol. 2010 Jan 15;337(2):405-14. doi: 10.1016/j.ydbio.2009.11.013. Epub 2009 Nov 13.

21.

Analysis of plasmin generation and clot lysis of plasma fibrinogen purified from a heterozygous dysfibrinogenemia, BbetaGly15Cys (Hamamatsu II).

Kamijyo Y, Hirota-Kawadobora M, Yamauchi K, Terasawa F, Honda T, Ikeya M, Okumura N.

Blood Coagul Fibrinolysis. 2009 Dec;20(8):726-32. doi: 10.1097/MBC.0b013e328332aa09.

PMID:
19809304
22.

Changes in blood parameters and coagulation-related gene expression in pregnant rats.

Urasoko Y, He XJ, Ebata T, Kinoshita Y, Kobayashi J, Mochizuki M, Ikeya M.

J Am Assoc Lab Anim Sci. 2009 May;48(3):272-8.

23.

5-fluorouracil-induced histopathological changes in the central nervous system of rat fetuses.

Yamaguchi Y, Aoki A, Fukunaga Y, Matsushima K, Ebata T, Ikeya M, Tamura K.

Histol Histopathol. 2009 Feb;24(2):133-9. doi: 10.14670/HH-24.133.

PMID:
19085829
24.

Studies of the toxicological potential of capsinoids: IX. Teratology studies of dihydrocapsiate in rats and rabbits.

Bernard BK, Watanabe E, Kodama T, Tsubuku S, Otabe A, Ikeya M, Matsuoka T, Masuyama T.

Int J Toxicol. 2008;27 Suppl 3:119-36. doi: 10.1080/10915810802513643.

PMID:
19037803
25.

Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice.

Ikeya M, Nosaka T, Fukushima K, Kawada M, Furuta Y, Kitamura T, Sasai Y.

Mech Dev. 2008 Sep-Oct;125(9-10):832-42. doi: 10.1016/j.mod.2008.06.011. Epub 2008 Jul 3.

26.

Galactosamine-induced acute liver injury in rats reduces hepatic alpha-tocopherol transfer protein production.

Takenaka A, Kita A, Ikeya M, Arai H, Igarashi K.

J Nutr Sci Vitaminol (Tokyo). 2007 Aug;53(4):366-71.

27.

The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo.

Arakawa A, Matsuo-Takasaki M, Takai A, Inomata H, Matsumura M, Ikeya M, Takahashi K, Miyachi Y, Sasai N, Sasai Y.

Dev Biol. 2007 Jun 1;306(1):160-9. Epub 2007 Mar 13.

28.

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.

Ikeya M, Kawada M, Kiyonari H, Sasai N, Nakao K, Furuta Y, Sasai Y.

Development. 2006 Nov;133(22):4463-73. Epub 2006 Oct 11.

29.

[A case report of autoimmune pancreatitis with abnormal elevation of CA19-9 and patholocal findings].

Kageyama F, Takehira Y, Yamada M, Murohisa G, Kataoka H, Sano M, Iwaoka Y, Kawata K, Takahashi Y, Ikeya M, Terai T, Noritake H, Watanabe S, Ogiku M, Nishiwaki Y, Ozawa T, Yasumi K.

Nihon Shokakibyo Gakkai Zasshi. 2006 Jan;103(1):57-63. Japanese. No abstract available.

PMID:
16444987
30.

Functional analysis of chick ONT1 reveals distinguishable activities among olfactomedin-related signaling factors.

Sakuragi M, Sasai N, Ikeya M, Kawada M, Onai T, Katahira T, Nakamura H, Sasai Y.

Mech Dev. 2006 Feb;123(2):114-23. Epub 2006 Jan 18.

31.

Gene disruption/knock-in analysis of mONT3: vector construction by employing both in vivo and in vitro recombinations.

Ikeya M, Kawada M, Nakazawa Y, Sakuragi M, Sasai N, Ueno M, Kiyonari H, Nakao K, Sasai Y.

Int J Dev Biol. 2005;49(7):807-23.

34.

Comparison of an oxidative stress biomarker "urinary8-hydroxy-2'-deoxyguanosine," between smokers and non-smokers.

Kanaya S, Ikeya M, Yamamoto K, Moriya T, Furuhashi K, Sonoda M, Goto K, Ochi H.

Biofactors. 2004;22(1-4):255-8.

PMID:
15630293
35.
36.

ESR study of Gd3+ and Mn2+ ions sorbed on hydroxyapatite.

Matsuda T, Yamanaka C, Ikeya M.

Appl Radiat Isot. 2005 Feb;62(2):353-7.

PMID:
15607474
38.

Possibility of precipitated CaCO3 with vitamin C as a new dosimetric material.

Sato H, Ikeya M.

Appl Radiat Isot. 2005 Feb;62(2):337-41.

PMID:
15607471
39.

Electron spin resonance of particulate soot samples from automobiles to help environmental studies.

Yamanaka C, Matsuda T, Ikeya M.

Appl Radiat Isot. 2005 Feb;62(2):307-11.

PMID:
15607466
40.

Nitrogen dioxide (NO2) created by gamma-rays in Antarctic ice and rime ice.

Yada T, Norizawa K, Tani A, Ikeya M.

Appl Radiat Isot. 2005 Feb;62(2):255-9.

PMID:
15607458
41.

Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells.

Mizuseki K, Sakamoto T, Watanabe K, Muguruma K, Ikeya M, Nishiyama A, Arakawa A, Suemori H, Nakatsuji N, Kawasaki H, Murakami F, Sasai Y.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):5828-33. Epub 2003 Apr 30.

42.

Mouse circadian rhythm before the Kobe earthquake in 1995.

Yokoi S, Ikeya M, Yagi T, Nagai K.

Bioelectromagnetics. 2003 May;24(4):289-91.

PMID:
12696089
43.

Prenatal upper gastrointestinal bleeding.

Ryo E, Ikeya M, Kasai Y, Sugimoto M.

Ultrasound Obstet Gynecol. 2002 Sep;20(3):308-10. No abstract available.

44.

Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord.

Muroyama Y, Fujihara M, Ikeya M, Kondoh H, Takada S.

Genes Dev. 2002 Mar 1;16(5):548-53.

45.

Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.

Nomi M, Oishi I, Kani S, Suzuki H, Matsuda T, Yoda A, Kitamura M, Itoh K, Takeuchi S, Takeda K, Akira S, Ikeya M, Takada S, Minami Y.

Mol Cell Biol. 2001 Dec;21(24):8329-35.

46.

Expression of vinexin alpha in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal.

Kawauchi T, Ikeya M, Takada S, Ueda K, Shirai M, Takihara Y, Kioka N, Amachi T.

Mech Dev. 2001 Aug;106(1-2):147-50.

47.

Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.

Matsuda T, Nomi M, Ikeya M, Kani S, Oishi I, Terashima T, Takada S, Minami Y.

Mech Dev. 2001 Jul;105(1-2):153-6.

49.

Radiation effects in dry ice: models for a peak on the Arrhenius curve

Norizawa K, Kanosue K, Ikeya M.

Appl Radiat Isot. 2000 May;52(5):1259-63.

PMID:
10836440
50.

Metal ion-organic compound for high sensitive ESR dosimetry

Hassan GM, Ikeya M.

Appl Radiat Isot. 2000 May;52(5):1247-54.

PMID:
10836438

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