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Risk Prediction Model for Major Adverse Outcome in Proximal Thoracic Aortic Surgery.

Wagner MA, Wang H, Benrashid E, Keenan JE, Ganapathi AM, Englum BR, Hughes GC.

Ann Thorac Surg. 2018 Nov 8. pii: S0003-4975(18)31620-5. doi: 10.1016/j.athoracsur.2018.09.052. [Epub ahead of print]


Acute aortic dissections with entry tear in the arch: A report from the International Registry of Acute Aortic Dissection.

Trimarchi S, de Beaufort HWL, Tolenaar JL, Bavaria JE, Desai ND, Di Eusanio M, Di Bartolomeo R, Peterson MD, Ehrlich M, Evangelista A, Montgomery DG, Myrmel T, Hughes GC, Appoo JJ, De Vincentiis C, Yan TD, Nienaber CA, Isselbacher EM, Deeb GM, Gleason TG, Patel HJ, Sundt TM, Eagle KA.

J Thorac Cardiovasc Surg. 2018 Sep 21. pii: S0022-5223(18)32352-3. doi: 10.1016/j.jtcvs.2018.07.101. [Epub ahead of print]


Trends in human immunodeficiency virus diagnoses among men who have sex with men in North America, Western Europe, and Australia, 2000-2014.

Chapin-Bardales J, Schmidt AJ, Guy RJ, Kaldor JM, McGregor S, Sasse A, Archibald C, Rank C, Casabona Barbarà J, Folch C, Vives N, Cowan SA, Cazein F, Velter A, An der Heiden M, Gunsenheimer-Bartmeyer B, Marcus U, Op de Coul ELM, van Sighem A, Aldir I, Cortes Martins H, Berglund T, Velicko I, Gebhardt M, Delpech V, Hughes G, Nardone A, Hall HI, Johnson AS, Sullivan PS.

Ann Epidemiol. 2018 Oct 9. pii: S1047-2797(18)30773-7. doi: 10.1016/j.annepidem.2018.09.006. [Epub ahead of print]


pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.

Jones GN, Rooney C, Griffin N, Roudier M, Young LA, Garcia-Trinidad A, Hughes GD, Whiteaker JR, Wilson Z, Odedra R, Zhao L, Ivey RG, Howat WJ, Harrington EA, Barrett JC, Ramos-Montoya A, Lau A, Paulovich AG, Cadogan EB, Pierce AJ.

Br J Cancer. 2018 Nov 2. doi: 10.1038/s41416-018-0286-4. [Epub ahead of print]


Mycoplasma genitalium: the next sexually transmitted superbug?

Hughes G, Saunders J.

BMJ. 2018 Oct 29;363:k4376. doi: 10.1136/bmj.k4376. No abstract available. Erratum in: BMJ. 2018 Oct 31;363:k4573.


STI Risk Perception in the British Population and How It Relates to Sexual Behaviour and STI Healthcare Use: Findings From a Cross-sectional Survey (Natsal-3).

Clifton S, Mercer CH, Sonnenberg P, Tanton C, Field N, Gravningen K, Hughes G, Mapp F, Johnson AM.

EClinicalMedicine. 2018 Aug-Sep;2-3:29-36. doi: 10.1016/j.eclinm.2018.08.001.


Point-of-care tests for chlamydia and gonorrhoea in Indigenous communities.

Hughes G, Fifer H.

Lancet Infect Dis. 2018 Oct;18(10):1054-1055. doi: 10.1016/S1473-3099(18)30486-9. No abstract available.


Not so crystal clear: observations from a case of crystalline arthritis with cytokine release syndrome (CRS) after chimeric antigen receptor (CAR)-T cell therapy.

Chung SH, Hughes G, Koffman B, Turtle CJ, Maloney DG, Acharya UH.

Bone Marrow Transplant. 2018 Oct 5. doi: 10.1038/s41409-018-0357-4. [Epub ahead of print] No abstract available.


Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone.

Griffin R, Psarelli EE, Cox TF, Khedr M, Milan AM, Davison AS, Hughes AT, Usher JL, Taylor S, Loftus N, Daroszewska A, West E, Jones A, Briggs M, Fisher M, McCormick M, Judd S, Vinjamuri S, Sireau N, Dillon JP, Devine JM, Hughes G, Harrold J, Barton GJ, Jarvis JC, Gallagher JA, Ranganath LR.

Data Brief. 2018 Sep 12;20:1620-1628. doi: 10.1016/j.dib.2018.09.021. eCollection 2018 Oct.


Microbiome Interaction Networks and Community Structure From Laboratory-Reared and Field-Collected Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus Mosquito Vectors.

Hegde S, Khanipov K, Albayrak L, Golovko G, Pimenova M, Saldaña MA, Rojas MM, Hornett EA, Motl GC, Fredregill CL, Dennett JA, Debboun M, Fofanov Y, Hughes GL.

Front Microbiol. 2018 Sep 10;9:2160. doi: 10.3389/fmicb.2018.02160. eCollection 2018.


Self-Expanding Transcatheter Aortic Valve Replacement or Surgical Valve Replacement in High-Risk Patients: 5-Year Outcomes.

Gleason TG, Reardon MJ, Popma JJ, Deeb GM, Yakubov SJ, Lee JS, Kleiman NS, Chetcuti S, Hermiller JB Jr, Heiser J, Merhi W, Zorn GL 3rd, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Conte JV, Mumtaz M, Oh JK, Huang J, Adams DH; CoreValve U.S. Pivotal High Risk Trial Clinical Investigators.

J Am Coll Cardiol. 2018 Sep 18. pii: S0735-1097(18)38290-1. doi: 10.1016/j.jacc.2018.08.2146. [Epub ahead of print]


In this October issue.

Hughes G.

Emerg Med Australas. 2018 Oct;30(5):599. doi: 10.1111/1742-6723.13176. No abstract available.


Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors.

Watt JE, Hughes GR, Walpole S, Monaco S, Stephenson GR, Bulman Page PC, Hemmings AM, Angulo J, Chantry A.

Chemistry. 2018 Sep 12. doi: 10.1002/chem.201804169. [Epub ahead of print]


The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure.

Wang A, Ganapathi AM, Wang A, Hughes GC.

J Heart Valve Dis. 2017 Nov;26(6):735-737.


Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry.

Vora AN, Dai D, Matsuoka R, Harrison JK, Hughes GC 4th, Sherwood MW, Piccini JP, Bhardwaj B, Lopes RD, Cohen D, Holmes DR Jr, Thourani VH, Peterson E, Kirtane A, Kapadia S, Vemulapalli S.

JACC Cardiovasc Interv. 2018 Sep 10;11(17):1746-1756. doi: 10.1016/j.jcin.2018.05.042.


AGILE: an assembled genome mining pipeline.

Hughes GM, Teeling EC.

Bioinformatics. 2018 Sep 4. doi: 10.1093/bioinformatics/bty781. [Epub ahead of print]


Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone.

Bhadra S, Riedel TE, Saldaña MA, Hegde S, Pederson N, Hughes GL, Ellington AD.

PLoS Negl Trop Dis. 2018 Aug 30;12(8):e0006671. doi: 10.1371/journal.pntd.0006671. eCollection 2018 Aug.


Classic hybrid arch debranching (type I hybrid arch repair) without circulatory arrest.

Hughes GC.

Ann Cardiothorac Surg. 2018 May;7(3):443-450. doi: 10.21037/acs.2018.05.06. No abstract available.


In this August issue.

Hughes G.

Emerg Med Australas. 2018 Aug;30(4):445. doi: 10.1111/1742-6723.13155. No abstract available.


Discovery of a Series of 3-Cinnoline Carboxamides as Orally Bioavailable, Highly Potent, and Selective ATM Inhibitors.

Barlaam B, Cadogan E, Campbell A, Colclough N, Dishington A, Durant S, Goldberg K, Hassall LA, Hughes GD, MacFaul PA, McGuire TM, Pass M, Patel A, Pearson S, Petersen J, Pike KG, Robb G, Stratton N, Xin G, Zhai B.

ACS Med Chem Lett. 2018 Jul 13;9(8):809-814. doi: 10.1021/acsmedchemlett.8b00200. eCollection 2018 Aug 9.


Sexual behaviours and sexually transmitted infection outcomes in a cohort of HIV-negative men who have sex with men attending sexual health clinics in England.

Desai S, Burns F, Schembri G, Williams D, Sullivan A, McOwan A, Antonucci S, Mercey D, Hughes G, Hart G, Gill ON, Nardone A.

Int J STD AIDS. 2018 Aug 16:956462418789333. doi: 10.1177/0956462418789333. [Epub ahead of print]


Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing.

Chaverra-Rodriguez D, Macias VM, Hughes GL, Pujhari S, Suzuki Y, Peterson DR, Kim D, McKeand S, Rasgon JL.

Nat Commun. 2018 Aug 1;9(1):3008. doi: 10.1038/s41467-018-05425-9.


Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.

Ranganath LR, Khedr M, Milan AM, Davison AS, Hughes AT, Usher JL, Taylor S, Loftus N, Daroszewska A, West E, Jones A, Briggs M, Fisher M, McCormick M, Judd S, Vinjamuri S, Griffin R, Psarelli EE, Cox TF, Sireau N, Dillon JP, Devine JM, Hughes G, Harrold J, Barton GJ, Jarvis JC, Gallagher JA.

Mol Genet Metab. 2018 Sep;125(1-2):127-134. doi: 10.1016/j.ymgme.2018.07.011. Epub 2018 Jul 24.


Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone.

Davison AS, Harrold JA, Hughes G, Norman BP, Devine J, Usher J, Hughes AT, Khedr M, Gallagher JA, Milan AM, J C G H, Ranganath LR.

Mol Genet Metab. 2018 Sep;125(1-2):135-143. doi: 10.1016/j.ymgme.2018.07.008. Epub 2018 Jul 19.


A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.

Paskins Z, Hughes G, Myers H, Hughes E, Hennings S, Cherrington A, Evans A, Holden M, Stevenson K, Menon A, Bromley K, Roberts P, Hall A, Peat G, Jinks C, Oppong R, Lewis M, Foster NE, Mallen C, Roddy E.

BMC Musculoskelet Disord. 2018 Jul 18;19(1):218. doi: 10.1186/s12891-018-2153-0.


Evaluation of a toolkit for standardizing clinical measures of muscle tone.

McGibbon CA, Sexton A, Hughes G, Wilson A, Jones M, O'Connell C, Parker K, Adans-Dester C, O'Brien A, Bonato P.

Physiol Meas. 2018 Aug 8;39(8):085001. doi: 10.1088/1361-6579/aad424.


Hydroxychloroquine: an update.

Hughes G.

Lupus. 2018 Aug;27(9):1402-1403. doi: 10.1177/0961203318787040. No abstract available.


Nursing students' knowledge, attitude and practices of infection prevention and control guidelines at a tertiary institution in the Western Cape: A cross sectional study.

Rahiman F, Chikte U, Hughes GD.

Nurse Educ Today. 2018 Oct;69:20-25. doi: 10.1016/j.nedt.2018.06.021. Epub 2018 Jun 30.


Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.

Eyre DW, Sanderson ND, Lord E, Regisford-Reimmer N, Chau K, Barker L, Morgan M, Newnham R, Golparian D, Unemo M, Crook DW, Peto TE, Hughes G, Cole MJ, Fifer H, Edwards A, Andersson MI.

Euro Surveill. 2018 Jul;23(27). doi: 10.2807/1560-7917.ES.2018.23.27.1800323.


Intestinal Myiasis Caused by Sarcophaga spp. in Cusco, Peru: A Case Report and Review of the Literature.

Ly P, Aizenberg A, Martin T, Lopez M, Arturo Saldaña M, Hughes GL, Cabada MM.

Case Rep Infect Dis. 2018 May 27;2018:3685439. doi: 10.1155/2018/3685439. eCollection 2018.


Thoracic endovascular aortic repair for the ascending aorta: experience and pitfalls.

Plichta RP, Hughes GC.

J Vis Surg. 2018 May 9;4:92. doi: 10.21037/jovs.2018.03.01. eCollection 2018. Review.


Response to Enoch et al.

Talento AF, Hughes G, Cottrell E, Bergin C.

J Hosp Infect. 2018 Oct;100(2):147-148. doi: 10.1016/j.jhin.2018.06.013. Epub 2018 Jun 20. No abstract available.


HIV incidence among sexual health clinic attendees in England: First estimates for black African heterosexuals using a biomarker, 2009-2013.

Aghaizu A, Tosswill J, De Angelis D, Ward H, Hughes G, Murphy G, Delpech V.

PLoS One. 2018 Jun 20;13(6):e0197939. doi: 10.1371/journal.pone.0197939. eCollection 2018.


Use of gender distribution in routine surveillance data to detect potential transmission of gastrointestinal infections among men who have sex with men in England.

Mook P, Gardiner D, Kanagarajah S, Kerac M, Hughes G, Field N, McCarthy N, Rawlings C, Simms I, Lane C, Crook PD.

Epidemiol Infect. 2018 Aug;146(11):1468-1477. doi: 10.1017/S0950268818001681. Epub 2018 Jun 20.


Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium.

Khan MR, Dudhia J, David FH, De Godoy R, Mehra V, Hughes G, Dakin SG, Carr AJ, Goodship AE, Smith RKW.

Stem Cell Res Ther. 2018 Jun 19;9(1):169. doi: 10.1186/s13287-018-0900-7.


Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy.

Jokl EJ, Hughes GL, Cracknell T, Pownall ME, Blanco G.

Dis Model Mech. 2018 Jul 6;11(7). pii: dmm033225. doi: 10.1242/dmm.033225.


Anticoagulation and Antiplatelet Strategies After On-X Mechanical Aortic Valve Replacement.

Puskas JD, Gerdisch M, Nichols D, Fermin L, Rhenman B, Kapoor D, Copeland J, Quinn R, Hughes GC, Azar H, McGrath M, Wait M, Kong B, Martin T, Douville EC, Meyer S, Ye J, Jamieson WRE, Landvater L, Hagberg R, Trotter T, Armitage J, Askew J, Accola K, Levy P, Duncan D, Yanagawa B, Ely J, Graeve A; PROACT Investigators.

J Am Coll Cardiol. 2018 Jun 19;71(24):2717-2726. doi: 10.1016/j.jacc.2018.03.535.


Full gait cycle analysis of lower limb and trunk kinematics and muscle activations during walking in participants with and without ankle instability.

Northeast L, Gautrey CN, Bottoms L, Hughes G, Mitchell ACS, Greenhalgh A.

Gait Posture. 2018 Jul;64:114-118. doi: 10.1016/j.gaitpost.2018.06.001. Epub 2018 Jun 7.


Persistence of an outbreak of gonorrhoea with high-level resistance to azithromycin in England, November 2014‒May 2018.

Smolarchuk C, Wensley A, Padfield S, Fifer H, Lee A, Hughes G.

Euro Surveill. 2018 Jun;23(23). doi: 10.2807/1560-7917.ES.2018.23.23.1800287.


Stroke and Cardiovascular Outcomes in Patients With Carotid Disease Undergoing Transcatheter Aortic Valve Replacement.

Kochar A, Li Z, Harrison JK, Hughes GC, Thourani VH, Mack MJ, Matsouaka RA, Cohen DJ, Peterson ED, Jones WS, Vemulapalli S.

Circ Cardiovasc Interv. 2018 Jun;11(6):e006322. doi: 10.1161/CIRCINTERVENTIONS.117.006322.


In this June issue.

Hughes G.

Emerg Med Australas. 2018 Jun;30(3):291. doi: 10.1111/1742-6723.13104. No abstract available.


Nitrogen reactive ion etch processes for the selective removal of poly-(4-vinylpyridine) in block copolymer films.

Flynn SP, Bogan J, Lundy R, Khalafalla KE, Shaw M, Rodriguez BJ, Swift P, Daniels S, O'Connor R, Hughes G, Kelleher SM.

Nanotechnology. 2018 Aug 31;29(35):355302. doi: 10.1088/1361-6528/aacae4. Epub 2018 Jun 6.


Cardiac β-adrenergic responsiveness of obese Zucker rats: The role of AMPK.

Bussey CT, Thaung HPA, Hughes G, Bahn A, Lamberts RR.

Exp Physiol. 2018 Aug;103(8):1067-1075. doi: 10.1113/EP087054. Epub 2018 Jun 29.


The Association Between Believing in Free Will and Subjective Well-Being Is Confounded by a Sense of Personal Control.

Gooding PLT, Callan MJ, Hughes G.

Front Psychol. 2018 May 7;9:623. doi: 10.3389/fpsyg.2018.00623. eCollection 2018.


Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial.

Tripathy D, Im SA, Colleoni M, Franke F, Bardia A, Harbeck N, Hurvitz SA, Chow L, Sohn J, Lee KS, Campos-Gomez S, Villanueva Vazquez R, Jung KH, Babu KG, Wheatley-Price P, De Laurentiis M, Im YH, Kuemmel S, El-Saghir N, Liu MC, Carlson G, Hughes G, Diaz-Padilla I, Germa C, Hirawat S, Lu YS.

Lancet Oncol. 2018 Jul;19(7):904-915. doi: 10.1016/S1470-2045(18)30292-4. Epub 2018 May 24.


Outcomes of Planned Two-Stage Hybrid Aortic Repair With Dacron-Replaced Proximal Landing Zone.

Ranney DN, Yerokun BA, Benrashid E, Bishawi M, Williams A, McCann RL, Hughes GC.

Ann Thorac Surg. 2018 Oct;106(4):1136-1142. doi: 10.1016/j.athoracsur.2018.04.044. Epub 2018 Aug 23.


Volatile and Contact Chemical Cues Associated with Host and Mate Recognition Behavior of Sphenophorus venatus and Sphenophorus parvulus (Coleoptera: Dryophthoridae).

Duffy AG, Hughes GP, Ginzel MD, Richmond DS.

J Chem Ecol. 2018 May 17. doi: 10.1007/s10886-018-0967-8. [Epub ahead of print]


Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.

Karlin J, Allen J, Ahmad SF, Hughes G, Sheridan V, Odedra R, Farrington P, Cadogan EB, Riches LC, Garcia-Trinidad A, Thomason AG, Patel B, Vincent J, Lau A, Pike KG, Hunt TA, Sule A, Valerie NCK, Biddlestone-Thorpe L, Kahn J, Beckta JM, Mukhopadhyay N, Barlaam B, Degorce SL, Kettle J, Colclough N, Wilson J, Smith A, Barrett IP, Zheng L, Zhang T, Wang Y, Chen K, Pass M, Durant ST, Valerie K.

Mol Cancer Ther. 2018 Aug;17(8):1637-1647. doi: 10.1158/1535-7163.MCT-17-0975. Epub 2018 May 16.


Management of dystonia in paediatric palliative care.

Slater T, Hughes G, Lumsden DE, Laddie J.

Arch Dis Child. 2018 May 16. pii: archdischild-2018-315002. doi: 10.1136/archdischild-2018-315002. [Epub ahead of print] No abstract available.


Analysing the role of complexity in explaining the fortunes of technology programmes: empirical application of the NASSS framework.

Greenhalgh T, Wherton J, Papoutsi C, Lynch J, Hughes G, A'Court C, Hinder S, Procter R, Shaw S.

BMC Med. 2018 May 14;16(1):66. doi: 10.1186/s12916-018-1050-6.

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