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Items: 46

1.

Botulinum Neurotoxins Serotypes A and B induce paralysis of mouse striated and smooth muscles with different potencies.

Maignel-Ludop J, Huchet M, Krupp J.

Pharmacol Res Perspect. 2017 Jan 31;5(1):e00289. doi: 10.1002/prp2.289. eCollection 2017 Feb.

2.

Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design.

Allan GM, Vicker N, Lawrence HR, Tutill HJ, Day JM, Huchet M, Ferrandis E, Reed MJ, Purohit A, Potter BV.

Bioorg Med Chem. 2008 Apr 15;16(8):4438-56. doi: 10.1016/j.bmc.2008.02.059. Epub 2008 Mar 7.

PMID:
18329273
3.

Butyl 2-(4-[1.1'-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain.

Liberatore AM, Schulz J, Favre-Guilmard C, Pommier J, Lannoy J, Pawlowski E, Barthelemy MA, Huchet M, Auguet M, Chabrier PE, Bigg D.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1746-9. Epub 2006 Dec 22.

PMID:
17234409
4.

Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.

Prévost GP, Lonchampt MO, Holbeck S, Attoub S, Zaharevitz D, Alley M, Wright J, Brezak MC, Coulomb H, Savola A, Huchet M, Chaumeron S, Nguyen QD, Forgez P, Bruyneel E, Bracke M, Ferrandis E, Roubert P, Demarquay D, Gespach C, Kasprzyk PG.

Cancer Res. 2006 Sep 15;66(18):9227-34.

5.

BN80927: a novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo.

Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Camara J, Kasprzyk PG, Prévost G, Bigg DC.

Cancer Res. 2004 Jul 15;64(14):4942-9.

6.

2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators.

Liberatore AM, Schulz J, Pommier J, Barthelemy MA, Huchet M, Chabrier PE, Bigg D.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3521-3.

PMID:
15177465
7.

A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.

Bailly C, Laine W, Baldeyrou B, Demarquay D, Huchet M, Coulomb H, Lanco C, Lavergne O, Bigg DC.

Anticancer Drug Des. 2001 Feb;16(1):27-36.

PMID:
11762642
8.

The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison.

Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Kasprzyk PG, Bailly C, Camara J, Bigg DC.

Anticancer Drugs. 2001 Jan;12(1):9-19.

PMID:
11272292
9.

The dual topoisomerase inhibitor, BN 80927, is highly potent against cell proliferation and tumor growth.

Huchet M, Demarquay D, Coulomb H, Kasprzyk P, Carlson M, Lauer J, Lavergne O, Bigg D.

Ann N Y Acad Sci. 2000;922:303-5. No abstract available.

PMID:
11193907
10.

The homocamptothecin, BN 80927, is a potent topoisomerase I poison and topoisomerase II catalytic inhibitor.

Demarquay D, Coulomb H, Huchet M, Lesueur-Ginot L, Camara J, Lavergne O, Bigg D.

Ann N Y Acad Sci. 2000;922:301-2. No abstract available.

PMID:
11193906
11.

Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins.

Lavergne O, Demarquay D, Bailly C, Lanco C, Rolland A, Huchet M, Coulomb H, Muller N, Baroggi N, Camara J, Le Breton C, Manginot E, Cazaux JB, Bigg DC.

J Med Chem. 2000 Jun 1;43(11):2285-9.

PMID:
10841808
12.

Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.

Bailly C, Lansiaux A, Dassonneville L, Demarquay D, Coulomb H, Huchet M, Lavergne O, Bigg DC.

Biochemistry. 1999 Nov 23;38(47):15556-63.

PMID:
10569939
13.

BN 80927: a novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II.

Lavergne O, Harnett J, Rolland A, Lanco C, Lesueur-Ginot L, Demarquay D, Huchet M, Coulomb H, Bigg DC.

Bioorg Med Chem Lett. 1999 Sep 6;9(17):2599-602.

PMID:
10498216
14.

Reduced antinociception in mice lacking neuronal nicotinic receptor subunits.

Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Léna C, Le Novère N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP.

Nature. 1999 Apr 29;398(6730):805-10.

PMID:
10235262
15.

The early expression of Rev-erbbeta occurs in the developing nervous system of mouse embryo.

Huchet M, Cassia R, Zakin L, Cereghini S, Zakin MM.

Cell Mol Biol (Noisy-le-grand). 1998 May;44(3):553-6.

PMID:
9620453
16.

Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle.

Antony C, Huchet M, Changeux JP, Cartaud J.

J Cell Biol. 1995 Aug;130(4):959-68.

17.

Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization.

Legay C, Huchet M, Massoulié J, Changeux JP.

Eur J Neurosci. 1995 Aug 1;7(8):1803-9.

PMID:
7582132
18.

New antineoplastic aza-phospholipids - synthesis, in-vitro cytotoxicity and differential cellular-sensitivity against 70 human tumor-cell lines.

Principe P, Broquet C, Paull K, Grever M, Coulomb H, Huchet M, Menciahuerta J, Braquet P.

Int J Oncol. 1994 Jan;4(1):29-36.

PMID:
21566885
19.

Compartmentalized expression of the alpha- and gamma-subunits of the acetylcholine receptor in recently fused myofibers.

Piette J, Huchet M, Houzelstein D, Changeux JP.

Dev Biol. 1993 May;157(1):205-13.

PMID:
8482411
20.

Localization of mRNAs coding for CMD1, myogenin and the alpha-subunit of the acetylcholine receptor during skeletal muscle development in the chicken.

Piette J, Huchet M, Duclert A, Fujisawa-Sehara A, Changeux JP.

Mech Dev. 1992 Mar;37(1-2):95-106.

PMID:
1318730
21.

Occurrence of neuropeptide K-like immunoreactivity in ventral horn cells of the chicken spinal cord during development.

Villar MJ, Roa M, Huchet M, Changeux JP, Valentino KL, Hökfelt T.

Brain Res. 1991 Feb 8;541(1):149-53.

PMID:
2029616
22.

Survival in vitro of motoneurons identified or purified by novel antibody-based methods is selectively enhanced by muscle-derived factors.

Bloch-Gallego E, Huchet M, el M'Hamdi H, Xie FK, Tanaka H, Henderson CE.

Development. 1991 Jan;111(1):221-32.

23.

Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor alpha-subunit gene.

Piette J, Bessereau JL, Huchet M, Changeux JP.

Nature. 1990 May 24;345(6273):353-5.

PMID:
2342565
24.

Immunoreactive Calcitonin Gene-Related Peptide, Vasoactive Intestinal Polypeptide, and Somatostatin in Developing Chicken Spinal Cord Motoneurons.

Villar MJ, Roa M, Huchet M, Hökfelt T, Changeux JP, Fahrenkrug J, Brown JC, Epstein M, Hersh L.

Eur J Neurosci. 1989 May;1(3):269-287.

PMID:
12106158
26.

A subpopulation of embryonic telencephalic neurons survive and develop in vitro in response to factors derived from the periphery.

Taguchi T, Huchet M, Roa M, Changeux JP, Henderson CE.

Brain Res. 1987 Dec 15;465(1-2):125-32.

PMID:
3440197
27.

Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons.

Henderson CE, Hauser SL, Huchet M, Dessi F, Hentati F, Taguchi T, Changeux JP, Fardeau M.

Neurology. 1987 Aug;37(8):1361-4.

PMID:
3614658
28.

Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases.

Hauser SL, Cazenave PA, Lyon-Caen O, Taguchi T, Huchet M, Nuret H, Changeux JP, Henderson CE.

Neurology. 1986 Dec;36(12):1614-8.

PMID:
3785679
29.

Increase of neurite-promoting activity for spinal neurons in muscles of 'paralysé' mice and tenotomised rats.

Henderson CE, Benoit P, Huchet M, Guenet JL, Changeux JP.

Brain Res. 1986 Feb;390(1):65-70.

PMID:
3948032
30.

[Assuming responsibility of a child with head injuries by a care team from the time of awakening to the time of socialization].

Leduc MF, Derrey N, Peltier F, Huchet M, Lanoiselée JM, Potagas C.

Soins Chir. 1985 Aug-Sep;(54-55):59-62. French. No abstract available.

PMID:
3852376
31.

[Orthostatic postural behavior of a population of aged subjects with atherosclerosis from the spectral analysis of their stabilogram].

Patat A, Foulhoux P, Huchet M, Memin Y, Venet R.

Agressologie. 1985 Jan;26(1):73-7. French. No abstract available.

PMID:
3876038
32.

Neurite-promoting activities for embryonic spinal neurons and their developmental changes in the chick.

Henderson CE, Huchet M, Changeux JP.

Dev Biol. 1984 Aug;104(2):336-47.

PMID:
6378691
33.

Denervation increases a neurite-promoting activity in extracts of skeletal muscle.

Henderson CE, Huchet M, Changeux JP.

Nature. 1983 Apr 14;302(5909):609-11.

PMID:
6835393
34.

Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells.

Henderson CE, Huchet M, Changeux JP.

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2625-9.

35.
36.

[Models in orcology].

Brunet M, Huchet M, Berlie J, Garbe E.

Nouv Presse Med. 1976 Jun 12;5(24):1541, 1543-4. French. No abstract available.

PMID:
940754
38.

A protein difference associated with defects of the Purkinje cell in staggerer and nervous mutant mice.

Mallet J, Huchet M, Pougeois R, Changeux JP.

FEBS Lett. 1975 Apr 1;52(2):216-20. No abstract available.

39.

Protein differences associated with the absence of granule cells in the cerebella from the mutant weaver mouse and from x-irradiated rat.

Mallet J, Huchet M, Shelanski M, Changeux JP.

FEBS Lett. 1974 Sep 15;46(1):243-6. No abstract available.

40.

Purification from Torpedo marmorata electric tissue of membrane fragments particularly rich in cholinergic receptor protein.

Cohen JB, Weber M, Huchet M, Changeux JP.

FEBS Lett. 1972 Oct 1;26(1):43-7. No abstract available.

41.

[Partial reconstitution of an excitable membrane after dissolution by sodium deoxycholate].

Changeux JP, Huchet M, Cartaud J.

C R Acad Sci Hebd Seances Acad Sci D. 1972 Jan 3;274(1):122-5. French. No abstract available.

PMID:
4622026
43.

[Separation of the receptor protein of acetylcholine and acetylcholinesterase].

Meunier JC, Huchet M, Boquet P, Changeux JP.

C R Acad Sci Hebd Seances Acad Sci D. 1971 Jan 4;272(1):117-20. French. No abstract available.

PMID:
4994956
44.

[Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine].

Changeux JP, Kasai M, Huchet M, Meunier JC.

C R Acad Sci Hebd Seances Acad Sci D. 1970 Jun 8;270(23):2864-7. French. No abstract available.

PMID:
4987937
45.

Purification of membrane fragments derived from the non excitable surface of the eel electroplax.

Bauman A, Changeux J, Benda P, Huchet M.

FEBS Lett. 1970 Jun 1;8(3):145-148. No abstract available.

46.

Specific binding of acetylcholine to acetylcholinesterase in the presence of eserine.

Changeux J, Leuzinger W, Huchet M.

FEBS Lett. 1968 Dec;2(2):77-80. No abstract available.

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