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Exosomes in cancer development and clinical applications.

Tai YL, Chen KC, Hsieh JT, Shen TL.

Cancer Sci. 2018 Jun 16. doi: 10.1111/cas.13697. [Epub ahead of print] Review.


Perceptions of a mobile health intervention for Community Case Management in Malawi: Opportunities and challenges for Health Surveillance Assistants in a community setting.

Chirambo GB, Hardy VE, Heavin C, O'Connor Y, O'Donoghue J, Mastellos N, Tran T, Hsieh J, Wu JT, Carlsson S, Andersson B, Muula AS, Thompson M.

Malawi Med J. 2018 Mar;30(1):6-12. doi: 10.4314/mmj.v30i1.2.


Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic Consequences.

Molusky MM, Hsieh J, Lee SX, Ramakrishnan R, Tascau L, Haeusler RA, Accili D, Tall AR.

Arterioscler Thromb Vasc Biol. 2018 May 31. pii: ATVBAHA.118.311212. doi: 10.1161/ATVBAHA.118.311212. [Epub ahead of print]


Bombesin functionalized 64Cu-copper sulfide nanoparticles for targeted imaging of orthotopic prostate cancer.

Cai H, Xie F, Mulgaonkar A, Chen L, Sun X, Hsieh JT, Peng F, Tian R, Li L, Wu C, Ai H.

Nanomedicine (Lond). 2018 May 22. doi: 10.2217/nnm-2018-0062. [Epub ahead of print]


Promoting porcelain-zirconia bonding using different atmospheric pressure gas plasmas.

Liu YC, Hsieh JP, Chen YC, Kang LL, Hwang CS, Chuang SF.

Dent Mater. 2018 May 18. pii: S0109-5641(17)31279-4. doi: 10.1016/ [Epub ahead of print]


KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function.

Gala K, Li Q, Sinha A, Razavi P, Dorso M, Sanchez-Vega F, Chung YR, Hendrickson R, Hsieh J, Berger M, Schultz N, Pastore A, Abdel-Wahab O, Chandarlapaty S.

Oncogene. 2018 May 14. doi: 10.1038/s41388-018-0273-5. [Epub ahead of print]


The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma.

McKay RR, Bossé D, Xie W, Wankowicz SAM, Flaifel A, Brandao R, Lalani AA, Martini DJ, Wei XX, Braun DA, Van Allen E, Castellano D, De Velasco G, Wells JC, Heng DY, Fay AP, Schutz FA, Hsu J, Pal SK, Lee JL, Hsieh JJ, Harshman LC, Signoretti S, Motzer RJ, Feldman D, Choueiri TK.

Cancer Immunol Res. 2018 May 10. doi: 10.1158/2326-6066.CIR-17-0475. [Epub ahead of print]


The conversion and deglycosylation of isoflavones and anthocyanins in black soymilk process.

Hsiao YH, Hsieh JF.

Food Chem. 2018 Sep 30;261:8-14. doi: 10.1016/j.foodchem.2018.03.152. Epub 2018 Apr 2.


Blooming Artifact Reduction in Coronary Artery Calcification by A New De-blooming Algorithm: Initial Study.

Li P, Xu L, Yang L, Wang R, Hsieh J, Sun Z, Fan Z, Leipsic JA.

Sci Rep. 2018 May 2;8(1):6945. doi: 10.1038/s41598-018-25352-5.


Functional CT assessment of extravascular contrast distribution volume and myocardial perfusion in acute myocardial infarction.

So A, Wisenberg G, Teefy P, Yadegari A, Bagur R, Hadway J, Morrison L, MacDonald A, Gaskin D, Butler J, Biernaski H, Skanes S, Park SD, Islam A, Hsieh J, Lee TY.

Int J Cardiol. 2018 Sep 1;266:15-23. doi: 10.1016/j.ijcard.2018.02.101. Epub 2018 Apr 26.


Autocrine CCL5 promotes tumor progression in esophageal squamous cell carcinoma in vitro.

Wu YC, Shen YC, Chang JW, Hsieh JJ, Chu Y, Wang CH.

Cytokine. 2018 Apr 26;110:94-103. doi: 10.1016/j.cyto.2018.04.027. [Epub ahead of print]


RASAL2 inhibits tumor angiogenesis via p-AKT/ETS1 signaling in bladder cancer.

Hui K, Wu S, Yue Y, Gu Y, Guan B, Wang X, Hsieh JT, Chang LS, He D, Wu K.

Cell Signal. 2018 Aug;48:38-44. doi: 10.1016/j.cellsig.2018.04.006. Epub 2018 Apr 24.


In silico toxicology protocols.

Myatt GJ, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A, Auerbach S, Beilke L, Bellion P, Benigni R, Bercu J, Booth ED, Bower D, Brigo A, Burden N, Cammerer Z, Cronin MTD, Cross KP, Custer L, Dettwiler M, Dobo K, Ford KA, Fortin MC, Gad-McDonald SE, Gellatly N, Gervais V, Glover KP, Glowienke S, Van Gompel J, Gutsell S, Hardy B, Harvey JS, Hillegass J, Honma M, Hsieh JH, Hsu CW, Hughes K, Johnson C, Jolly R, Jones D, Kemper R, Kenyon MO, Kim MT, Kruhlak NL, Kulkarni SA, Kümmerer K, Leavitt P, Majer B, Masten S, Miller S, Moser J, Mumtaz M, Muster W, Neilson L, Oprea TI, Patlewicz G, Paulino A, Lo Piparo E, Powley M, Quigley DP, Reddy MV, Richarz AN, Ruiz P, Schilter B, Serafimova R, Simpson W, Stavitskaya L, Stidl R, Suarez-Rodriguez D, Szabo DT, Teasdale A, Trejo-Martin A, Valentin JP, Vuorinen A, Wall BA, Watts P, White AT, Wichard J, Witt KL, Woolley A, Woolley D, Zwickl C, Hasselgren C.

Regul Toxicol Pharmacol. 2018 Jul;96:1-17. doi: 10.1016/j.yrtph.2018.04.014. Epub 2018 Apr 17.


Intermittent Hypoxia Inhibits Na+-H+ Exchange-Mediated Acid Extrusion Via Intracellular Na+ Accumulation in Cardiomyocytes.

Chang HR, Lien CF, Jeng JR, Hsieh JC, Chang CW, Lin JH, Yang KT.

Cell Physiol Biochem. 2018;46(3):1252-1262. doi: 10.1159/000489076. Epub 2018 Apr 16.


Curcumin accelerates cutaneous wound healing via multiple biological actions: The involvement of TNF-α, MMP-9, α-SMA, and collagen.

Yen YH, Pu CM, Liu CW, Chen YC, Chen YC, Liang CJ, Hsieh JH, Huang HF, Chen YL.

Int Wound J. 2018 Apr 16. doi: 10.1111/iwj.12904. [Epub ahead of print]


Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, Hazell S, Eichler-Jonsson C, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Jabbar F, Spain L, Lall S, Guarch R, Falzon M, Proctor I, Pickering L, Gore M, Watkins TBK, Ward S, Stewart A, DiNatale R, Becerra MF, Reznik E, Hsieh JJ, Richmond TA, Mayhew GF, Hill SM, McNally CD, Jones C, Rosenbaum H, Stanislaw S, Burgess DL, Alexander NR, Swanton C; PEACE; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):581-594.e12. doi: 10.1016/j.cell.2018.03.057. Epub 2018 Apr 12.


Electroencephalographic delta/alpha frequency activity differentiates psychotic disorders: a study of schizophrenia, bipolar disorder and methamphetamine-induced psychotic disorder.

Howells FM, Temmingh HS, Hsieh JH, van Dijen AV, Baldwin DS, Stein DJ.

Transl Psychiatry. 2018 Apr 12;8(1):75. doi: 10.1038/s41398-018-0105-y. Review.


The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.

Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG; Cancer Genome Atlas Research Network, Spellman PT, Rathmell WK, Linehan WM.

Cell Rep. 2018 Apr 3;23(1):313-326.e5. doi: 10.1016/j.celrep.2018.03.075.


Passive Detection of Atrial Fibrillation Using a Commercially Available Smartwatch.

Tison GH, Sanchez JM, Ballinger B, Singh A, Olgin JE, Pletcher MJ, Vittinghoff E, Lee ES, Fan SM, Gladstone RA, Mikell C, Sohoni N, Hsieh J, Marcus GM.

JAMA Cardiol. 2018 May 1;3(5):409-416. doi: 10.1001/jamacardio.2018.0136.


CD40-mediated HIF-1α expression underlying microangiopathy in diabetic nerve pathology.

Kan HW, Hsieh JH, Chien HF, Lin YH, Yeh TY, Chao CC, Hsieh ST.

Dis Model Mech. 2018 Apr 26;11(4). pii: dmm033647. doi: 10.1242/dmm.033647.


Improving the food waste composting facilities site selection for sustainable development using a hybrid modified MADM model.

Liu KM, Lin SH, Hsieh JC, Tzeng GH.

Waste Manag. 2018 May;75:44-59. doi: 10.1016/j.wasman.2018.02.017. Epub 2018 Mar 2.


Effect of germination on composition profiling and antioxidant activity of the polysaccharide-protein conjugate in black soybean [Glycinemax (L.) Merr.].

Lee AL, Yu YP, Hsieh JF, Kuo MI, Ma YS, Lu CP.

Int J Biol Macromol. 2018 Jul 1;113:601-606. doi: 10.1016/j.ijbiomac.2018.02.145. Epub 2018 Feb 24.


A Prognostic Model Based on Circulating Tumour Cells is Useful for Identifying the Poorest Survival Outcome in Patients with Metastatic Colorectal Cancer.

Chou WC, Wu MH, Chang PH, Hsu HC, Chang GJ, Huang WK, Wu CE, Hsieh JC.

Int J Biol Sci. 2018 Jan 12;14(2):137-146. doi: 10.7150/ijbs.23182. eCollection 2018.


HIF-1α promotes ZEB1 expression and EMT in a human bladder cancer lung metastasis animal model.

Zhu J, Huang Z, Zhang M, Wang W, Liang H, Zeng J, Wu K, Wang X, Hsieh JT, Guo P, Fan J.

Oncol Lett. 2018 Mar;15(3):3482-3489. doi: 10.3892/ol.2018.7764. Epub 2018 Jan 10.


A high-throughput approach to identify specific neurotoxicants/ developmental toxicants in human neuronal cell function assays.

Delp J, Gutbier S, Klima S, Hoelting L, Pinto-Gil K, Hsieh JH, Aichem M, Klein K, Schreiber F, Tice RR, Pastor M, Behl M, Leist M.

ALTEX. 2018 Jan 21. doi: 10.14573/altex.1712182. [Epub ahead of print]


Circadian anosmia: A rare clinical presentation.

Landis BN, Hsieh JW, Coppin G.

Laryngoscope. 2018 Feb 5. doi: 10.1002/lary.27106. [Epub ahead of print]


In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R)-4-Fluoroglutamine.

Dunphy MPS, Harding JJ, Venneti S, Zhang H, Burnazi EM, Bromberg J, Omuro AM, Hsieh JJ, Mellinghoff IK, Staton K, Pressl C, Beattie BJ, Zanzonico PB, Gerecitano JF, Kelsen DP, Weber W, Lyashchenko SK, Kung HF, Lewis JS.

Radiology. 2018 May;287(2):667-675. doi: 10.1148/radiol.2017162610. Epub 2018 Jan 31.


Cilium Length and Intraflagellar Transport Regulation by Kinases PKG-1 and GCK-2 in Caenorhabditis elegans Sensory Neurons.

Muthaiyan Shanmugam M, Bhan P, Huang HY, Hsieh J, Hua TE, Wu GH, Punjabi H, Lee Aplícano VD, Chen CW, Wagner OI.

Mol Cell Biol. 2018 Mar 15;38(7). pii: e00612-17. doi: 10.1128/MCB.00612-17. Print 2018 Apr 1.


Family Related Factors and Concurrent Heroin Use in Methadone Maintenance Treatment in China.

Feng N, Lin C, Hsieh J, Rou K, Li L.

Subst Use Misuse. 2018 Jan 29:1-7. doi: 10.1080/10826084.2018.1424913. [Epub ahead of print]


Tox21 Enricher: Web-based Chemical/Biological Functional Annotation Analysis Tool Based on Tox21 Toxicity Screening Platform.

Hur J, Danes L, Hsieh JH, McGregor B, Krout D, Auerbach S.

Mol Inform. 2018 May;37(5):e1700129. doi: 10.1002/minf.201700129. Epub 2018 Jan 29.


Functional Characteristics of the Flying Squirrel's Cecal Microbiota under a Leaf-Based Diet, Based on Multiple Meta-Omic Profiling.

Lu HP, Liu PY, Wang YB, Hsieh JF, Ho HC, Huang SW, Lin CY, Hsieh CH, Yu HT.

Front Microbiol. 2018 Jan 4;8:2622. doi: 10.3389/fmicb.2017.02622. eCollection 2017.


Updates on the molecular epidemiology of Enterovirus D68 after installation of screening test among acute flaccid paralysis patients in Taiwan.

Wei HY, Yeh TK, Hsieh JY, Lin IP, Yang JY.

J Microbiol Immunol Infect. 2018 Jan 3. pii: S1684-1182(17)30264-5. doi: 10.1016/j.jmii.2017.12.001. [Epub ahead of print]


The Hospice Information System and its association with the congruence between the preferred and actual place of death.

Lin HR, Wang JH, Hsieh JG, Wang YW, Kao SL.

Ci Ji Yi Xue Za Zhi. 2017 Oct-Dec;29(4):213-217. doi: 10.4103/tcmj.tcmj_125_17.


Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision.

Hsieh JJ, Le V, Cao D, Cheng EH, Creighton CJ.

J Pathol. 2018 Apr;244(5):525-537. doi: 10.1002/path.5022. Epub 2018 Feb 14. Review.


Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia.

Hsieh J, Liu JW, Harn HJ, Hsueh KW, Rajamani K, Deng YC, Chia CM, Shyu WC, Lin SZ, Chiou TW.

Cell Transplant. 2017 Oct;26(10):1611-1621. doi: 10.1177/0963689717732578.


You Have Brains in Your Head, You Have Organoids in Your Dish, You Can Steer Yourself in any Direction You Wish.

Thodeson DM, Hsieh J.

Epilepsy Curr. 2017 Sep-Oct;17(5):311-313. doi: 10.5698/1535-7597.17.5.311. No abstract available.


Ultra-low dose quantitative CT myocardial perfusion imaging with sparse-view dynamic acquisition and image reconstruction: A feasibility study.

Enjilela E, Lee TY, Hsieh J, Wisenberg G, Teefy P, Yadegari A, Bagur R, Islam A, Branch K, So A.

Int J Cardiol. 2018 Mar 1;254:272-281. doi: 10.1016/j.ijcard.2017.11.030. Epub 2017 Nov 16.


Identification of Estrogen-Related Receptor α Agonists in the Tox21 Compound Library.

Lynch C, Zhao J, Huang R, Kanaya N, Bernal L, Hsieh JH, Auerbach SS, Witt KL, Merrick BA, Chen S, Teng CT, Xia M.

Endocrinology. 2018 Feb 1;159(2):744-753. doi: 10.1210/en.2017-00658.


ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival.

Wang GX, Tu HC, Dong Y, Skanderup AJ, Wang Y, Takeda S, Ganesan YT, Han S, Liu H, Hsieh JJ, Cheng EH.

Cell Rep. 2017 Dec 5;21(10):2926-2939. doi: 10.1016/j.celrep.2017.11.030.


Development of an in Vitro-Based Risk Assessment Framework for Predicting Ambient Particulate Matter-Bound Polycyclic Aromatic Hydrocarbon-Activated Toxicity Pathways.

Chou WC, Hsu CY, Ho CC, Hsieh JH, Chiang HC, Tsou TC, Chen YC, Lin P.

Environ Sci Technol. 2017 Dec 19;51(24):14262-14272. doi: 10.1021/acs.est.7b02002. Epub 2017 Dec 1.


Encoding of menstrual pain experience with theta oscillations in women with primary dysmenorrhea.

Lee PS, Low I, Chen YS, Tu CH, Chao HT, Hsieh JC, Chen LF.

Sci Rep. 2017 Nov 22;7(1):15977. doi: 10.1038/s41598-017-16039-4.


[Improve the Rate of Bone Collection at Human Tissue Banks].

Hsieh JM, Chung PS, Liu SP.

Hu Li Za Zhi. 2017 Dec;64(6):85-90. doi: 10.6224/JN.000086. Chinese.


Dose Dependencies and Biocompatibility of Renal Clearable Gold Nanoparticles: From Mice to Non-human Primates.

Xu J, Yu M, Peng C, Carter P, Tian J, Ning X, Zhou Q, Tu Q, Zhang G, Dao A, Jiang X, Kapur P, Hsieh JT, Zhao X, Liu P, Zheng J.

Angew Chem Int Ed Engl. 2018 Jan 2;57(1):266-271. doi: 10.1002/anie.201710584. Epub 2017 Dec 5.


Transcriptome Profiling of Melaleuca quinquenervia Challenged by Myrtle Rust Reveals Differences in Defense Responses Among Resistant Individuals.

Hsieh JF, Chuah A, Patel HR, Sandhu KS, Foley WJ, Külheim C.

Phytopathology. 2018 Apr;108(4):495-509. doi: 10.1094/PHYTO-09-17-0307-R. Epub 2018 Feb 14.


Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations.

Manley BJ, Reznik E, Ghanaat M, Kashan M, Becerra MF, Casuscelli J, Tennenbaum D, Redzematovic A, Carlo MI, Sato Y, Arcila M, Voss MH, Feldman DR, Motzer RJ, Russo P, Coleman J, Hsieh JJ, Hakimi AA.

Urol Oncol. 2017 Nov 10. pii: S1078-1439(17)30549-5. doi: 10.1016/j.urolonc.2017.10.012. [Epub ahead of print]


A microdialysis-based analytical system for dynamic monitoring of arsenic transformation under microbial activity.

Hsu KC, Hsieh JR, Chen YC, Hsu PF, Hung CC, Huang YL.

Analyst. 2017 Dec 4;142(24):4737-4743. doi: 10.1039/c7an01399j.


Incorporation of a Ligand Peptide for Immune Inhibitory Receptor LAIR-1 on Biomaterial Surfaces Inhibits Macrophage Inflammatory Responses.

Kim YK, Chu SH, Hsieh JY, Kamoku CM, Tenner AJ, Liu WF, Wang SW.

Adv Healthc Mater. 2017 Dec;6(24). doi: 10.1002/adhm.201700707. Epub 2017 Oct 30.


Thoracoscopic purse-string suture technique for managing superior vena caval impalement from central venous catheterization.

Liu YW, Lee YL, Hsieh JS, Lee JY, Chou SH.

J Trauma Acute Care Surg. 2017 Nov;83(5):899-902. doi: 10.1097/TA.0000000000001653. No abstract available.


SMELL-S and SMELL-R: Olfactory tests not influenced by odor-specific insensitivity or prior olfactory experience.

Hsieh JW, Keller A, Wong M, Jiang RS, Vosshall LB.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11275-11284. doi: 10.1073/pnas.1711415114. Epub 2017 Oct 10.


Disparity of end-of-life care in cancer patients with and without schizophrenia: A nationwide population-based cohort study.

Huang HK, Wang YW, Hsieh JG, Hsieh CJ.

Schizophr Res. 2018 May;195:434-440. doi: 10.1016/j.schres.2017.10.029. Epub 2017 Oct 21.


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