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Items: 13

1.

Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.

O'Donoghue AJ, Ivry SL, Chaudhury C, Hostetter DR, Hanahan D, Craik CS.

Biol Chem. 2016 Sep 1;397(9):871-81. doi: 10.1515/hsz-2016-0138.

2.

Imaging active urokinase plasminogen activator in prostate cancer.

LeBeau AM, Sevillano N, Markham K, Winter MB, Murphy ST, Hostetter DR, West J, Lowman H, Craik CS, VanBrocklin HF.

Cancer Res. 2015 Apr 1;75(7):1225-35. doi: 10.1158/0008-5472.CAN-14-2185. Epub 2015 Feb 11.

3.

Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index.

Desnoyers LR, Vasiljeva O, Richardson JH, Yang A, Menendez EE, Liang TW, Wong C, Bessette PH, Kamath K, Moore SJ, Sagert JG, Hostetter DR, Han F, Gee J, Flandez J, Markham K, Nguyen M, Krimm M, Wong KR, Liu S, Daugherty PS, West JW, Lowman HB.

Sci Transl Med. 2013 Oct 16;5(207):207ra144. doi: 10.1126/scitranslmed.3006682.

4.

Global identification of peptidase specificity by multiplex substrate profiling.

O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS.

Nat Methods. 2012 Nov;9(11):1095-100. doi: 10.1038/nmeth.2182. Epub 2012 Sep 30.

5.

Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis.

Ray M, Hostetter DR, Loeb CR, Simko J, Craik CS.

Prostate. 2012 Jun 1;72(8):846-55. doi: 10.1002/pros.21486. Epub 2011 Sep 14.

6.

Human and mouse granzyme M display divergent and species-specific substrate specificities.

de Poot SA, Westgeest M, Hostetter DR, Van Damme P, Plasman K, Demeyer K, Broekhuizen R, Gevaert K, Craik CS, Bovenschen N.

Biochem J. 2011 Aug 1;437(3):431-42. doi: 10.1042/BJ20110210.

PMID:
21564021
7.

Prediction of protease substrates using sequence and structure features.

Barkan DT, Hostetter DR, Mahrus S, Pieper U, Wells JA, Craik CS, Sali A.

Bioinformatics. 2010 Jul 15;26(14):1714-22. doi: 10.1093/bioinformatics/btq267. Epub 2010 May 26.

8.

Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration.

Duriseti S, Goetz DH, Hostetter DR, LeBeau AM, Wei Y, Craik CS.

J Biol Chem. 2010 Aug 27;285(35):26878-88. doi: 10.1074/jbc.M109.077677. Epub 2010 May 25.

9.

Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level.

Jun YW, Sheikholeslami S, Hostetter DR, Tajon C, Craik CS, Alivisatos AP.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17735-40. doi: 10.1073/pnas.0907367106. Epub 2009 Oct 1.

10.

Temperature dependence of myosin-II tail fragment assembly.

McMahon PM, Hostetter DR, Rice SE.

J Muscle Res Cell Motil. 2008;29(2-5):109-18. doi: 10.1007/s10974-008-9144-y. Epub 2008 Sep 11.

PMID:
18784979
11.

Hip is a pro-survival substrate of granzyme B.

Hostetter DR, Loeb CR, Chu F, Craik CS.

J Biol Chem. 2007 Sep 21;282(38):27865-74. Epub 2007 Jul 9.

12.

The myosin coiled-coil is a truly elastic protein structure.

Schwaiger I, Sattler C, Hostetter DR, Rief M.

Nat Mater. 2002 Dec;1(4):232-5.

PMID:
12618784
13.

Partially formed native tertiary interactions in the A-state of cytochrome c.

Hostetter DR, Weatherly GT, Beasley JR, Bortone K, Cohen DS, Finger SA, Hardwidge P, Kakouras DS, Saunders AJ, Trojak SK, Waldner JC, Pielak GJ.

J Mol Biol. 1999 Jun 11;289(3):639-44.

PMID:
10356334

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