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Items: 32

1.

Discovery and characterization of a novel dihydroisoxazole class of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiators.

Patel NC, Schwarz J, Hou XJ, Hoover DJ, Xie L, Fliri AJ, Gallaschun RJ, Lazzaro JT, Bryce DK, Hoffmann WE, Hanks AN, McGinnis D, Marr ES, Gazard JL, Hajós M, Scialis RJ, Hurst RS, Shaffer CL, Pandit J, O'Donnell CJ.

J Med Chem. 2013 Nov 27;56(22):9180-91. doi: 10.1021/jm401274b. Epub 2013 Nov 11.

PMID:
24215237
2.

Expression of the chitinase family glycoprotein YKL-40 in undifferentiated, differentiated and trans-differentiated mesenchymal stem cells.

Hoover DJ, Zhu V, Chen R, Briley K Jr, Rameshwar P, Cohen S, Coffman FD.

PLoS One. 2013 May 9;8(5):e62491. doi: 10.1371/journal.pone.0062491. Print 2013. Erratum in: PLoS One. 2014;9(4):e96230. Briley, Ken [corrected to Briley, Kenneth Jr].

3.

Nonpeptidic lysosomal modulators derived from z-phe-ala-diazomethylketone for treating protein accumulation diseases.

Viswanathan K, Hoover DJ, Hwang J, Wisniewski ML, Ikonne US, Bahr BA, Wright DL.

ACS Med Chem Lett. 2012 Sep 9;3(11):920-4. doi: 10.1021/ml300197h. eCollection 2012 Nov 8.

4.

Prophylactic mastectomy in high risk patients: a practice-based review of the indications. Do we follow guidelines?

Hoover DJ, Paragi PR, Santoro E, Schafer S, Chamberlain RS.

Breast Dis. 2010;31(1):19-27. doi: 10.3233/BD-2009-0291.

PMID:
20519802
5.

Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

Ekins S, Mankowski DC, Hoover DJ, Lawton MP, Treadway JL, Harwood HJ Jr.

Drug Metab Dispos. 2007 Mar;35(3):493-500. Epub 2006 Dec 28. Erratum in: Drug Metab Dispos. 2007 Jul;35(7):1246.

6.

Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors.

Yu LJ, Chen Y, Treadway JL, McPherson RK, McCoid SC, Gibbs EM, Hoover DJ.

J Pharmacol Exp Ther. 2006 Jun;317(3):1230-7. Epub 2006 Mar 14.

7.

Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.

Harwood HJ Jr, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL.

J Lipid Res. 2005 Mar;46(3):547-63. Epub 2004 Dec 16.

8.

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL.

Chem Biol. 2002 Aug;9(8):915-24.

9.

Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus.

Treadway JL, Mendys P, Hoover DJ.

Expert Opin Investig Drugs. 2001 Mar;10(3):439-54. Review.

PMID:
11227044
10.

X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.

Cronin NB, Badasso MO, J Tickle I, Dreyer T, Hoover DJ, Rosati RL, Humblet CC, Lunney EA, Cooper JB.

J Mol Biol. 2000 Nov 10;303(5):745-60.

PMID:
11061973
11.

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ.

Chem Biol. 2000 Sep;7(9):677-82.

12.

Lead interaction with human protamine (HP2) as a mechanism of male reproductive toxicity.

Quintanilla-Vega B, Hoover DJ, Bal W, Silbergeld EK, Waalkes MP, Anderson LD.

Chem Res Toxicol. 2000 Jul;13(7):594-600.

PMID:
10898591
13.
14.

Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.

Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL.

J Med Chem. 1998 Jul 30;41(16):2934-8. No abstract available.

PMID:
9685232
15.

Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo.

Martin WH, Hoover DJ, Armento SJ, Stock IA, McPherson RK, Danley DE, Stevenson RW, Barrett EJ, Treadway JL.

Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1776-81.

16.

The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae.

Aguilar CF, Cronin NB, Badasso M, Dreyer T, Newman MP, Cooper JB, Hoover DJ, Wood SP, Johnson MS, Blundell TL.

J Mol Biol. 1997 Apr 11;267(4):899-915.

PMID:
9135120
17.

Discovery of inhibitors of human renin with high oral bioavailability.

Hoover DJ, Lefker BA, Rosati RL, Wester RT, Kleinman EF, Bindra JS, Holt WF, Murphy WR, Mangiapane ML, Hockel GM, et al.

Adv Exp Med Biol. 1995;362:167-80.

PMID:
8540316
18.

Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes.

Parris KD, Hoover DJ, Damon DB, Davies DR.

Biochemistry. 1992 Sep 8;31(35):8125-41.

PMID:
1525154
19.

Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases.

Veerapandian B, Cooper JB, Sali A, Blundell TL, Rosati RL, Dominy BW, Damon DB, Hoover DJ.

Protein Sci. 1992 Mar;1(3):322-8.

21.

X-ray analysis of a difluorostatone renin inhibitor bound as the tetrahedral hydrate to the aspartic protease endothiapepsin.

Hoover DJ, Veerapandian B, Cooper JB, Damon DB, Dominy BW, Rosati RL, Blundell TL.

Adv Exp Med Biol. 1991;306:269-73. No abstract available.

PMID:
1812716
22.

Crystal structures of rhizopuspepsin/inhibitor complexes.

Parris KD, Hoover DJ, Davies DR.

Adv Exp Med Biol. 1991;306:217-31. No abstract available.

PMID:
1812709
25.

Pharmacokinetics of erythromycin in foals and in adult horses.

Prescott JF, Hoover DJ, Dohoo IR.

J Vet Pharmacol Ther. 1983 Mar;6(1):67-73.

PMID:
6854734
26.

Hormonal control of inhibin secretion.

Anderson LD, Hoover DJ.

Adv Exp Med Biol. 1982;147:53-78. No abstract available.

PMID:
6817606
27.

The role of nonsteroidal regulators in control of oocyte and follicular maturation.

Channing CP, Anderson LD, Hoover DJ, Kolena J, Osteen KG, Pomerantz SH, Tanabe K.

Recent Prog Horm Res. 1982;38:331-408. Review. No abstract available.

PMID:
6289394
28.

Inhibitory effects of porcine follicular fluid on monkey serum FSH levels and follicular maturation.

Channing CP, Anderson LD, Hoover DJ, Gagliano P, Hodgen G.

Biol Reprod. 1981 Nov;25(4):885-903. No abstract available.

PMID:
6796149
29.

Relationship between human follicular fluid inhibin F activity and steroid content.

Channing CP, Gagliano P, Hoover DJ, Tanabe K, Batta SK, Sulewski J, Lebech P.

J Clin Endocrinol Metab. 1981 Jun;52(6):1193-8. No abstract available.

PMID:
7014598
30.

Acetaldehyde concentration in rat blood and brain during the calcium carbimide--ethanol interaction.

Hoover DJ, Brien JF.

Can J Physiol Pharmacol. 1981 Jan;59(1):65-70.

PMID:
7214210
31.

Gas-liquid chromatographic determination of ethanol and acetaldehyde in tissues.

Brien JF, Hoover DJ.

J Pharmacol Methods. 1980 Aug;4(1):51-8.

PMID:
7401649
32.

Ozone deterioration.

Hoover DJ.

Hosp Top. 1976 May-Jun;54(3):45-6. No abstract available.

PMID:
1278918

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