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Items: 1 to 50 of 794

1.

A Case of Intractable Hemophagocytic Syndrome Associated with Systemic Lupus Erythematosus Resistant to Corticosteroids and Intravenous Cyclophosphamide that Was Successfully Treated with Cyclosporine A.

Toko H, Tsuboi H, Umeda N, Honda F, Ohyama A, Takahashi H, Abe S, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sumida T.

Intern Med. 2018 May 18. doi: 10.2169/internalmedicine.0571-17. [Epub ahead of print]

2.

Dynamics of sister chromatids through the cell cycle: Together and apart.

Takahashi M, Hirota T.

J Cell Biol. 2018 May 15. pii: jcb.201804091. doi: 10.1083/jcb.201804091. [Epub ahead of print]

PMID:
29764905
3.

Quantitative analyses of the metaphase-to-anaphase transition reveal differential kinetic regulation for securin and cyclin B1.

Konishi M, Shindo N, Komiya M, Tanaka K, Itoh T, Hirota T.

Biomed Res. 2018;39(2):75-85. doi: 10.2220/biomedres.39.75.

4.

Positive association of plasma leptin with sleep quality in obese type 2 diabetes patients.

Hirota T, Morioka T, Yoda K, Toi N, Hayashi N, Maruo S, Yamazaki Y, Kurajoh M, Motoyama K, Yamada S, Shoji T, Emoto M, Inaba M.

J Diabetes Investig. 2018 Feb 26. doi: 10.1111/jdi.12826. [Epub ahead of print]

5.

Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene.

Takechi T, Hirota T, Sakai T, Maeda N, Kobayashi D, Ieiri I.

Drug Metab Dispos. 2018 May;46(5):628-635. doi: 10.1124/dmd.117.079061. Epub 2018 Feb 2.

PMID:
29437875
6.

Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T.

Nat Cell Biol. 2018 Apr;20(4):503. doi: 10.1038/s41556-018-0044-0.

PMID:
29434373
7.

Clinical practice guideline for Sjögren's syndrome 2017.

Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I, Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nishiyama S, Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H.

Mod Rheumatol. 2018 May;28(3):383-408. doi: 10.1080/14397595.2018.1438093. Epub 2018 Mar 13.

PMID:
29409370
8.

Vacuolar Protein Degradation via Autophagy Provides Substrates to Amino Acid Catabolic Pathways as an Adaptive Response to Sugar Starvation in Arabidopsis thaliana.

Hirota T, Izumi M, Wada S, Makino A, Ishida H.

Plant Cell Physiol. 2018 Jan 30. doi: 10.1093/pcp/pcy005. [Epub ahead of print]

PMID:
29390157
9.

Protective effect of a newly developed fucose-deficient recombinant antithrombin against histone-induced endothelial damage.

Iba T, Hirota T, Sato K, Nagaoka I.

Int J Hematol. 2018 May;107(5):528-534. doi: 10.1007/s12185-018-2402-x. Epub 2018 Jan 20.

PMID:
29353463
10.

Patients' Characteristics and Clinical Course of Hypertrophic Cardiomyopathy in a Regional Japanese Cohort - Results From Kochi RYOMA Study.

Kubo T, Hirota T, Baba Y, Ochi Y, Takahashi A, Yamasaki N, Hamashige N, Yamamoto K, Kondo F, Bando K, Yamada E, Furuno T, Yabe T, Doi YL, Kitaoka H.

Circ J. 2018 Feb 23;82(3):824-830. doi: 10.1253/circj.CJ-17-0845. Epub 2018 Jan 13.

11.

Conformational dynamics of human protein kinase CK2α and its effect on function and inhibition.

Srivastava A, Hirota T, Irle S, Tama F.

Proteins. 2018 Mar;86(3):344-353. doi: 10.1002/prot.25444. Epub 2017 Dec 25.

PMID:
29243286
12.

Boron and nitrogen co-doped ordered microporous carbons with high surface areas.

Castro-Muñiz A, Nishihara H, Hirota T, Ohwada M, Li LX, Tsuda T, Kuwabata S, Maruyama J, Kyotani T.

Chem Commun (Camb). 2017 Dec 14;53(100):13348-13351. doi: 10.1039/c7cc08390d.

PMID:
29192698
13.

Association of interleukin 1 receptor-like 1 gene polymorphisms with eosinophilic phenotype in Japanese adults with asthma.

Inoue H, Ito I, Niimi A, Matsumoto H, Oguma T, Tajiri T, Iwata T, Nagasaki T, Kanemitsu Y, Morishima T, Hirota T, Tamari M, Wenzel SE, Mishima M.

Respir Investig. 2017 Nov;55(6):338-347. doi: 10.1016/j.resinv.2017.08.006. Epub 2017 Sep 22.

PMID:
29153414
14.

DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line.

ElInati E, Russell HR, Ojarikre OA, Sangrithi M, Hirota T, de Rooij DG, McKinnon PJ, Turner JMA.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12536-12541. doi: 10.1073/pnas.1712530114. Epub 2017 Nov 7.

15.

How important is allergic sensitization as a cause of atopic asthma?

Kanazawa J, Masuko H, Yamada H, Yatagai Y, Sakamoto T, Kitazawa H, Iijima H, Naito T, Hirota T, Tamari M, Hizawa N.

Allergol Int. 2018 Apr;67(2):292-294. doi: 10.1016/j.alit.2017.10.005. Epub 2017 Nov 2. No abstract available.

16.
17.

Population Pharmacodynamic Analysis of Uric Acid-Lowering Effects of Febuxostat Based on Electronic Medical Records in Two Hospitals.

Muraki S, Moriki K, Shigematsu S, Fukae M, Kakara M, Yamashita D, Hirota T, Takane H, Shimada M, Hirakawa M, Ieiri I.

J Clin Pharmacol. 2017 Oct 18. doi: 10.1002/jcph.1023. [Epub ahead of print]

PMID:
29045766
18.

Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.

Hirata J, Hirota T, Ozeki T, Kanai M, Sudo T, Tanaka T, Hizawa N, Nakagawa H, Sato S, Mushiroda T, Saeki H, Tamari M, Okada Y.

J Invest Dermatol. 2018 Mar;138(3):542-548. doi: 10.1016/j.jid.2017.10.001. Epub 2017 Oct 12.

19.

Recurrent Kikuchi-Fujimoto Disease Successfully Treated by the Concomitant Use of Hydroxychloroquine and Corticosteroids.

Honda F, Tsuboi H, Toko H, Ohyama A, Takahashi H, Abe S, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sumida T.

Intern Med. 2017 Dec 15;56(24):3373-3377. doi: 10.2169/internalmedicine.9205-17. Epub 2017 Oct 11.

20.

Fertile offspring from sterile sex chromosome trisomic mice.

Hirota T, Ohta H, Powell BE, Mahadevaiah SK, Ojarikre OA, Saitou M, Turner JMA.

Science. 2017 Sep 1;357(6354):932-935. doi: 10.1126/science.aam9046. Epub 2017 Aug 17.

21.

Synthesis of ordered carbonaceous frameworks from organic crystals.

Nishihara H, Hirota T, Matsuura K, Ohwada M, Hoshino N, Akutagawa T, Higuchi T, Jinnai H, Koseki Y, Kasai H, Matsuo Y, Maruyama J, Hayasaka Y, Konaka H, Yamada Y, Yamaguchi S, Kamiya K, Kamimura T, Nobukuni H, Tani F.

Nat Commun. 2017 Jul 24;8(1):109. doi: 10.1038/s41467-017-00152-z.

22.

Diffusion-weighted magnetic resonance imaging of parotid glands before and after abatacept therapy in patients with Sjögren's syndrome associated with rheumatoid arthritis: Utility to evaluate and predict response to treatment.

Takahashi H, Tsuboi H, Yokosawa M, Asashima H, Hirota T, Kondo Y, Matsumoto I, Sumida T.

Mod Rheumatol. 2018 Mar;28(2):300-307. doi: 10.1080/14397595.2017.1349234. Epub 2017 Jul 19.

PMID:
28722506
23.

Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies.

Hatori M, Gronfier C, Van Gelder RN, Bernstein PS, Carreras J, Panda S, Marks F, Sliney D, Hunt CE, Hirota T, Furukawa T, Tsubota K.

NPJ Aging Mech Dis. 2017 Jun 16;3:9. doi: 10.1038/s41514-017-0010-2. eCollection 2017. Review.

24.

Association study of childhood food allergy with genome-wide association studies-discovered loci of atopic dermatitis and eosinophilic esophagitis.

Hirota T, Nakayama T, Sato S, Yanagida N, Matsui T, Sugiura S, Takaoka Y, Hizawa N, Fujieda S, Miyatake A, Sasaki T, Amagai M, Doi S, Ito K, Ebisawa M, Tamari M.

J Allergy Clin Immunol. 2017 Dec;140(6):1713-1716. doi: 10.1016/j.jaci.2017.05.034. Epub 2017 Jun 16. No abstract available.

PMID:
28629743
25.

cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren's syndrome.

Takahashi H, Tsuboi H, Asashima H, Hirota T, Kondo Y, Moriyama M, Matsumoto I, Nakamura S, Sumida T.

Clin Exp Immunol. 2017 Oct;190(1):96-109. doi: 10.1111/cei.13000. Epub 2017 Jul 21.

PMID:
28621822
26.

Suppression of GPI-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands.

Hirota T, Tsuboi H, Takahashi H, Asashima H, Ohta M, Wakasa Y, Matsumoto I, Takaiwa F, Sumida T.

Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(1):28-34. doi: 10.2177/jsci.40.28. Review. Japanese.

27.

Functional Analysis of Dendritic Cells Generated from T-iPSCs from CD4+ T Cell Clones of Sjögren's Syndrome.

Iizuka-Koga M, Asashima H, Ando M, Lai CY, Mochizuki S, Nakanishi M, Nishimura T, Tsuboi H, Hirota T, Takahashi H, Matsumoto I, Otsu M, Sumida T.

Stem Cell Reports. 2017 May 9;8(5):1155-1163. doi: 10.1016/j.stemcr.2017.04.010.

28.

The Prevalence of Internet Addiction Among a Japanese Adolescent Psychiatric Clinic Sample With Autism Spectrum Disorder and/or Attention-Deficit Hyperactivity Disorder: A Cross-Sectional Study.

So R, Makino K, Fujiwara M, Hirota T, Ohcho K, Ikeda S, Tsubouchi S, Inagaki M.

J Autism Dev Disord. 2017 Jul;47(7):2217-2224. doi: 10.1007/s10803-017-3148-7.

PMID:
28474226
29.

Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients.

Tsuboi H, Hagiwara S, Asashima H, Takahashi H, Hirota T, Noma H, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Matsumoto I, Sumida T.

Ann Rheum Dis. 2017 Dec;76(12):1980-1985. doi: 10.1136/annrheumdis-2016-210758. Epub 2017 Mar 22.

30.

Intervertebral disc calcification with ossification of the posterior longitudinal ligament.

Mizukawa K, Kobayashi T, Yamada N, Hirota T.

Pediatr Int. 2017 May;59(5):622-624. doi: 10.1111/ped.13243. Epub 2017 Mar 21.

PMID:
28326638
31.

IL4Rα and ADAM33 as genetic markers in asthma exacerbations and type-2 inflammatory endotype.

Sunadome H, Matsumoto H, Petrova G, Kanemitsu Y, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Nagasaki T, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Hirota T, Tamari M, Yokoyama T, Niimi A, Izuhara K, Mishima M.

Clin Exp Allergy. 2017 Aug;47(8):998-1006. doi: 10.1111/cea.12927. Epub 2017 Apr 21.

PMID:
28326636
32.

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP.

Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y.

J Pharm Sci. 2017 Sep;106(9):2688-2694. doi: 10.1016/j.xphs.2017.03.010. Epub 2017 Mar 18.

PMID:
28322941
33.

Optimum soil frost depth to alleviate climate change effects in cold region agriculture.

Yanai Y, Iwata Y, Hirota T.

Sci Rep. 2017 Mar 21;7:44860. doi: 10.1038/srep44860.

34.

Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations.

Kanazawa J, Masuko H, Yatagai Y, Sakamoto T, Yamada H, Kaneko Y, Kitazawa H, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N.

Allergol Int. 2017 Oct;66(4):563-567. doi: 10.1016/j.alit.2017.02.012. Epub 2017 Mar 17.

35.

Effects of Simvastatin on Alveolar Regeneration and Its Relationship to Exposure in Mice with Dexamethasone-Induced Emphysema.

Hirooka S, Ueno M, Fukuda S, Miyajima A, Hirota T.

Biol Pharm Bull. 2017;40(2):155-160. doi: 10.1248/bpb.b16-00637.

36.

Prognostic Significance of Non-Dilated Left Ventricular Size and Mitral Regurgitation in Patients With Dilated Phase of Hypertrophic Cardiomyopathy.

Kubo T, Baba Y, Hirota T, Tanioka K, Yamasaki N, Doi YL, Kitaoka H.

Int Heart J. 2017 Feb 7;58(1):63-68. doi: 10.1536/ihj.16-109. Epub 2017 Jan 11.

37.

Staphylococcus aureus enterotoxin sensitization involvement and its association with the CysLTR1 variant in different asthma phenotypes.

Matsumoto H, Kanemitsu Y, Nagasaki T, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Izuhara Y, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Ono J, Ohta S, Hirota T, Kawaguchi T, Tamari M, Yokoyama T, Tabara Y, Matsuda F, Izuhara K, Niimi A, Mishima M.

Ann Allergy Asthma Immunol. 2017 Feb;118(2):197-203. doi: 10.1016/j.anai.2016.11.013. Epub 2016 Dec 27.

PMID:
28034578
38.

N-terminal pro-brain natriuretic peptide is a useful marker to identify latent heart failure patients in older adults in a rural outpatient clinic.

Hamagawa K, Kubo T, Nishimura K, Baba Y, Hirota T, Yamasaki N, Kitaoka H.

Geriatr Gerontol Int. 2017 Oct;17(10):1648-1653. doi: 10.1111/ggi.12951. Epub 2016 Nov 17.

PMID:
27860152
39.

Population pharmacokinetic-pharmacodynamic modeling and model-based prediction of docetaxel-induced neutropenia in Japanese patients with non-small cell lung cancer.

Fukae M, Shiraishi Y, Hirota T, Sasaki Y, Yamahashi M, Takayama K, Nakanishi Y, Ieiri I.

Cancer Chemother Pharmacol. 2016 Nov;78(5):1013-1023. Epub 2016 Oct 5.

PMID:
27709284
40.

Pharmacokinetics of ivermectin applied topically by whole-body bathing method in healthy volunteers.

Miyajima A, Hirota T, Tashiro M, Noguchi W, Kawano Y, Hanawa T, Kigure A, Anata T, Yamamoto Y, Yuasa N, Koshino M, Shiraishi Y, Yuzawa K, Akagi K, Yoshimasu T, Makigami K, Komoda M.

J Dermatol. 2017 Apr;44(4):406-413. doi: 10.1111/1346-8138.13628. Epub 2016 Oct 15.

PMID:
27743408
41.

RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjögren's syndrome-like sialadenitis.

Tahara M, Tsuboi H, Segawa S, Asashima H, Iizuka-Koga M, Hirota T, Takahashi H, Kondo Y, Matsui M, Matsumoto I, Sumida T.

Clin Exp Immunol. 2017 Feb;187(2):213-224. doi: 10.1111/cei.12868. Epub 2016 Oct 11.

42.

Condensin I-mediated mitotic chromosome assembly requires association with chromokinesin KIF4A.

Takahashi M, Wakai T, Hirota T.

Genes Dev. 2016 Sep 1;30(17):1931-6. doi: 10.1101/gad.282855.116. Epub 2016 Sep 15.

43.

Epigenetic regulation of drug transporter expression in human tissues.

Hirota T, Tanaka T, Takesue H, Ieiri I.

Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):19-30. Epub 2016 Sep 7. Review.

PMID:
27579666
44.

Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines.

Gotanda K, Hirota T, Saito J, Fukae M, Egashira Y, Izumi N, Deguchi M, Kimura M, Matsuki S, Irie S, Ieiri I.

Sci Rep. 2016 Aug 30;6:32299. doi: 10.1038/srep32299.

45.

Prevalence and clinical features of Fabry disease in Japanese male patients with diagnosis of hypertrophic cardiomyopathy.

Kubo T, Ochi Y, Baba Y, Hirota T, Tanioka K, Yamasaki N, Yoshimitsu M, Higuchi K, Takenaka T, Nakajima K, Togawa T, Tsukimura T, Sano S, Tei C, Sakuraba H, Kitaoka H.

J Cardiol. 2017 Jan;69(1):302-307. doi: 10.1016/j.jjcc.2016.05.014. Epub 2016 Aug 21.

46.

Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase.

Hirota T, Tsuboi H, Iizuka-Koga M, Takahashi H, Asashima H, Yokosawa M, Kondo Y, Ohta M, Wakasa Y, Matsumoto I, Takaiwa F, Sumida T.

Mod Rheumatol. 2017 May;27(3):457-465. doi: 10.1080/14397595.2016.1218598. Epub 2017 Feb 1.

PMID:
27539357
47.

Effectiveness of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis. An open label, multicenter, one-year, prospective study: ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjögren's syndrome Endocrinopathy) trial.

Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Yagishita M, Takahashi H, Kurata I, Ohyama A, Honda F, Asashima H, Miki H, Umeda N, Kondo Y, Hirata S, Saito K, Tanaka Y, Horai Y, Nakamura H, Kawakami A, Sumida T.

Mod Rheumatol. 2016 Nov;26(6):891-899. doi: 10.3109/14397595.2016.1158773. Epub 2016 Jul 26.

PMID:
27459020
48.

Chromosomal instability: A common feature and a therapeutic target of cancer.

Tanaka K, Hirota T.

Biochim Biophys Acta. 2016 Aug;1866(1):64-75. doi: 10.1016/j.bbcan.2016.06.002. Epub 2016 Jun 21. Review.

PMID:
27345585
49.

Population pharmacodynamic analysis of hemoglobin A1c-lowering effects by adding treatment of DPP-4 inhibitors (sitagliptin) in type 2 diabetes mellitus patients based on electronic medical records.

Kakara M, Nomura H, Ezaki M, Fukae M, Hirota T, Matsubayashi S, Hirakawa M, Ieiri I.

J Diabetes Complications. 2016 Sep-Oct;30(7):1282-6. doi: 10.1016/j.jdiacomp.2016.06.009. Epub 2016 Jun 14.

PMID:
27338508
50.

Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers.

Ikuta N, Okamoto H, Furune T, Uekaji Y, Terao K, Uchida R, Iwamoto K, Miyajima A, Hirota T, Sakamoto N.

Int J Mol Sci. 2016 Jun 15;17(6). pii: E949. doi: 10.3390/ijms17060949.

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