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Items: 17

1.

HEx: A heterologous expression platform for the discovery of fungal natural products.

Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME.

Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr.

2.

Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain.

Hang L, Tang MC, Harvey CJB, Page CG, Li J, Hung YS, Liu N, Hillenmeyer ME, Tang Y.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9556-9560. doi: 10.1002/anie.201705237. Epub 2017 Jul 5.

PMID:
28679030
3.

Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli.

Vandova GA, O'Brien RV, Lowry B, Robbins TF, Fischer CR, Davis RW, Khosla C, Harvey CJ, Hillenmeyer ME.

J Antibiot (Tokyo). 2017 Jul;70(7):859-863. doi: 10.1038/ja.2017.38. Epub 2017 Apr 12. No abstract available.

4.

Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.

Li YF, Tsai KJS, Harvey CJB, Li JJ, Ary BE, Berlew EE, Boehman BL, Findley DM, Friant AG, Gardner CA, Gould MP, Ha JH, Lilley BK, McKinstry EL, Nawal S, Parry RC, Rothchild KW, Silbert SD, Tentilucci MD, Thurston AM, Wai RB, Yoon Y, Aiyar RS, Medema MH, Hillenmeyer ME, Charkoudian LK.

Fungal Genet Biol. 2016 Apr;89:18-28. doi: 10.1016/j.fgb.2016.01.012. Epub 2016 Jan 22.

5.

Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters.

Hillenmeyer ME, Vandova GA, Berlew EE, Charkoudian LK.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13952-7. doi: 10.1073/pnas.1511688112. Epub 2015 Oct 23.

6.

Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast.

Tang MC, Lin HC, Li D, Zou Y, Li J, Xu W, Cacho RA, Hillenmeyer ME, Garg NK, Tang Y.

J Am Chem Soc. 2015 Nov 4;137(43):13724-7. doi: 10.1021/jacs.5b06108. Epub 2015 Oct 21.

7.

Computational identification and analysis of orphan assembly-line polyketide synthases.

O'Brien RV, Davis RW, Khosla C, Hillenmeyer ME.

J Antibiot (Tokyo). 2014 Jan;67(1):89-97. doi: 10.1038/ja.2013.125. Epub 2013 Dec 4.

8.

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action.

Hillenmeyer ME, Ericson E, Davis RW, Nislow C, Koller D, Giaever G.

Genome Biol. 2010;11(3):R30. doi: 10.1186/gb-2010-11-3-r30. Epub 2010 Mar 12.

9.

Comparative analysis of the global transcriptome of Anopheles funestus from Mali, West Africa.

Serazin AC, Dana AN, Hillenmeyer ME, Lobo NF, Coulibaly MB, Willard MB, Harker BW, Sharakhov IV, Collins FH, Ribeiro JM, Besansky NJ.

PLoS One. 2009 Nov 19;4(11):e7976. doi: 10.1371/journal.pone.0007976.

10.

The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.

11.

Update of the Anopheles gambiae PEST genome assembly.

Sharakhova MV, Hammond MP, Lobo NF, Krzywinski J, Unger MF, Hillenmeyer ME, Bruggner RV, Birney E, Collins FH.

Genome Biol. 2007;8(1):R5.

12.

Introns regulate RNA and protein abundance in yeast.

Juneau K, Miranda M, Hillenmeyer ME, Nislow C, Davis RW.

Genetics. 2006 Sep;174(1):511-8. Epub 2006 Jul 2.

13.
14.

Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast.

Deutschbauer AM, Jaramillo DF, Proctor M, Kumm J, Hillenmeyer ME, Davis RW, Nislow C, Giaever G.

Genetics. 2005 Apr;169(4):1915-25. Epub 2005 Feb 16.

15.

Gene expression patterns associated with blood-feeding in the malaria mosquito Anopheles gambiae.

Dana AN, Hong YS, Kern MK, Hillenmeyer ME, Harker BW, Lobo NF, Hogan JR, Romans P, Collins FH.

BMC Genomics. 2005 Jan 14;6:5.

16.

Inversions and gene order shuffling in Anopheles gambiae and A. funestus.

Sharakhov IV, Serazin AC, Grushko OG, Dana A, Lobo N, Hillenmeyer ME, Westerman R, Romero-Severson J, Costantini C, Sagnon N, Collins FH, Besansky NJ.

Science. 2002 Oct 4;298(5591):182-5.

17.

The genome sequence of the malaria mosquito Anopheles gambiae.

Holt RA, Subramanian GM, Halpern A, Sutton GG, Charlab R, Nusskern DR, Wincker P, Clark AG, Ribeiro JM, Wides R, Salzberg SL, Loftus B, Yandell M, Majoros WH, Rusch DB, Lai Z, Kraft CL, Abril JF, Anthouard V, Arensburger P, Atkinson PW, Baden H, de Berardinis V, Baldwin D, Benes V, Biedler J, Blass C, Bolanos R, Boscus D, Barnstead M, Cai S, Center A, Chaturverdi K, Christophides GK, Chrystal MA, Clamp M, Cravchik A, Curwen V, Dana A, Delcher A, Dew I, Evans CA, Flanigan M, Grundschober-Freimoser A, Friedli L, Gu Z, Guan P, Guigo R, Hillenmeyer ME, Hladun SL, Hogan JR, Hong YS, Hoover J, Jaillon O, Ke Z, Kodira C, Kokoza E, Koutsos A, Letunic I, Levitsky A, Liang Y, Lin JJ, Lobo NF, Lopez JR, Malek JA, McIntosh TC, Meister S, Miller J, Mobarry C, Mongin E, Murphy SD, O'Brochta DA, Pfannkoch C, Qi R, Regier MA, Remington K, Shao H, Sharakhova MV, Sitter CD, Shetty J, Smith TJ, Strong R, Sun J, Thomasova D, Ton LQ, Topalis P, Tu Z, Unger MF, Walenz B, Wang A, Wang J, Wang M, Wang X, Woodford KJ, Wortman JR, Wu M, Yao A, Zdobnov EM, Zhang H, Zhao Q, Zhao S, Zhu SC, Zhimulev I, Coluzzi M, della Torre A, Roth CW, Louis C, Kalush F, Mural RJ, Myers EW, Adams MD, Smith HO, Broder S, Gardner MJ, Fraser CM, Birney E, Bork P, Brey PT, Venter JC, Weissenbach J, Kafatos FC, Collins FH, Hoffman SL.

Science. 2002 Oct 4;298(5591):129-49.

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